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A novel DNA intercalator, 8-methoxy pyrimido[4′,5′:4,5]thieno (2,3-b)quinoline-4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor.
- Published in:
- Molecular Carcinogenesis, 2013, v. 52, n. 6, p. 413, doi. 10.1002/mc.21867
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- Article
MicroRNA, miR-501 regulate the V(D)J recombination in B cells.
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- Biochemical Journal, 2023, v. 480, n. 24, p. 2061, doi. 10.1042/BCJ20230250
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- Article
ST08 Altered NF-κB Pathway in Breast Cancer Cells In Vitro as Revealed by miRNA-mRNA Analysis and Enhanced the Effect of Cisplatin on Tumour Reduction in EAC Mouse Model.
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- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.835027
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- Article
Differential genomic arrangements in Caryophyllales through deep transcriptome sequencing of A. hypochondriacus.
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- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0180528
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- Article
Znc2 module of RAG1 contributes towards structure-specific nuclease activity of RAGs.
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- Biochemical Journal, 2020, v. 477, n. 18, p. 3567, doi. 10.1042/BCJ20200361
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- Article
Good Cop, Bad Cop: Profiling the Immune Landscape in Multiple Myeloma.
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- Biomolecules (2218-273X), 2023, v. 13, n. 11, p. 1629, doi. 10.3390/biom13111629
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- Article
Identification and characterization of mercaptopyrimidine‐based small molecules as inhibitors of nonhomologous DNA end joining.
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- FEBS Journal, 2023, v. 290, n. 3, p. 796, doi. 10.1111/febs.16615
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- Article
Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner.
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- FEBS Journal, 2018, v. 285, n. 21, p. 3959, doi. 10.1111/febs.14661
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- Article
Identification of a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain.
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- FEBS Journal, 2016, v. 283, n. 18, p. 3408, doi. 10.1111/febs.13815
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- Article
A Coumarin–Imidazothiadiazole Derivative, SP11 Abrogates Tumor Growth by Targeting HSP90 and Its Client Proteins.
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- Molecules, 2023, v. 28, n. 13, p. 5226, doi. 10.3390/molecules28135226
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- Article
ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models.
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- Molecules, 2020, v. 25, n. 19, p. 4499, doi. 10.3390/molecules25194499
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- Article
Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis.
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- Cells (2073-4409), 2023, v. 12, n. 9, p. 1228, doi. 10.3390/cells12091228
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- Article
Expression of circulating tumour cells in oral squamous cell carcinoma: An ex vivo pilot study.
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- Journal of Oral & Maxillofacial Pathology (0973029X), 2023, v. 27, n. 3, p. 489, doi. 10.4103/jomfp.jomfp_131_23
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- Article
Whole transcriptome sequencing reveals HOXD11-AGAP3, a novel fusion transcript in the Indian acute leukemia cohort.
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- Frontiers in Genetics, 2023, v. 14, p. 1, doi. 10.3389/fgene.2023.1100587
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- Article
Multi-omics analysis of the Indian ovarian cancer cohort revealed histotype-specific mutation and gene expression patterns.
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- Frontiers in Genetics, 2023, v. 14, p. 01, doi. 10.3389/fgene.2023.1102114
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- Article
Exposure to endosulfan can cause long term effects on general biology, including the reproductive system of mice.
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- Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.1047746
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- Article
Integrated Transcriptome and Metabolomic Analysis Reveal Anti-Angiogenic Properties of Disarib, a Novel Bcl2-Specific Inhibitor.
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- Genes, 2022, v. 13, n. 7, p. 1208, doi. 10.3390/genes13071208
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- Article
Efficiency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism.
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- Cellular & Molecular Life Sciences, 2011, v. 68, n. 4, p. 661, doi. 10.1007/s00018-010-0472-x
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- Article
Genome-wide differential DNA methylation analysis of MDA-MB-231 breast cancer cells treated with curcumin derivatives, ST08 and ST09.
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- BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-09041-2
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- Article
Regioselective synthesis and biological studies of novel 1-aryl-3, 5-bis (het) aryl pyrazole derivatives as potential antiproliferative agents.
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- Molecular & Cellular Biochemistry, 2017, v. 426, n. 1/2, p. 149, doi. 10.1007/s11010-016-2887-7
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- Article
Curcumin alters distinct molecular pathways in breast cancer subtypes revealed by integrated miRNA/mRNA expression analysis.
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- Cancer Reports, 2022, v. 5, n. 10, p. 1, doi. 10.1002/cnr2.1596
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- Article
SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining.
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- Cancer Reports, 2021, v. 4, n. 3, p. 1, doi. 10.1002/cnr2.1341
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- Article
Triple-negative breast cancer: A run-through of features, classification and current therapies.
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- Oncology Letters, 2021, v. 22, n. 1, p. N.PAG
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- Article
MiRAGDB: A Knowledgebase of RAG Regulators.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.863110
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- Article
Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells
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- FEBS Letters, 2008, v. 582, n. 29, p. 4066, doi. 10.1016/j.febslet.2008.11.001
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- Article
Nonamer dependent RAG cleavage at CpGs can explain mechanism of chromosomal translocations associated to lymphoid cancers.
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- PLoS Genetics, 2022, v. 18, n. 10, p. 1, doi. 10.1371/journal.pgen.1010421
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- Article
Evolutionary conservation of the gene Cvsox9 in the lizard, Calotes versicolor, and its expression during gonadal differentiation.
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- Development Genes & Evolution, 2000, v. 210, n. 5, p. 250, doi. 10.1007/s004270050311
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- Article
Classification of Grain Amaranths Using Chromosome-Level Genome Assembly of Ramdana, A. hypochondriacus.
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- Frontiers in Plant Science, 2020, v. 11, p. N.PAG, doi. 10.3389/fpls.2020.579529
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- Article
Propyl-2-(8-(3,4-Difluorobenzyl)-2′,5′-Dioxo-8-Azaspiro[Bicyclo[3.2.1] Octane-3,4′-Imidazolidine]-1′-yl) Acetate Induces Apoptosis in Human Leukemia Cells through Mitochondrial Pathway following Cell Cycle Arrest.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069103
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- Article
Extracts of Strawberry Fruits Induce Intrinsic Pathway of Apoptosis in Breast Cancer Cells and Inhibits Tumor Progression in Mice.
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- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047021
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- Article
Novel Levamisole Derivative Induces Extrinsic Pathway of Apoptosis in Cancer Cells and Inhibits Tumor Progression in Mice.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0043632
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- Publication type:
- Article
The Draft Genome and Transcriptome of Amaranthus hypochondriacus: A C4 Dicot Producing High-Lysine Edible Pseudo-Cereal.
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- DNA Research, 2014, v. 21, n. 6, p. 585, doi. 10.1093/dnares/dsu021
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- Article
A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells.
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- Investigational New Drugs, 2011, v. 29, n. 4, p. 523, doi. 10.1007/s10637-009-9379-5
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- Article
A novel DNA intercalator, butylamino-pyrimido[4′,5′:4,5]selenolo(2,3-b)quinoline, induces cell cycle arrest and apoptosis in leukemic cells.
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- Investigational New Drugs, 2010, v. 28, n. 1, p. 35, doi. 10.1007/s10637-008-9212-6
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- Article
The genome trilogy of Anopheles stephensi, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07462-3
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- Publication type:
- Article
Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02454-1
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- Article
Acute toxicity analysis of an inhibitor of BCL2, Disarib, in rats.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89387-x
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- Article
SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation.
- Published in:
- Molecular Carcinogenesis, 2021, v. 60, n. 9, p. 627, doi. 10.1002/mc.23329
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- Publication type:
- Article
Characterization of DNA double‐strand break repair pathways in diffuse large B cell lymphoma.
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- Molecular Carcinogenesis, 2019, v. 58, n. 2, p. 219, doi. 10.1002/mc.22921
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- Article
Identification and characterization of novel ligase I inhibitors.
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- Molecular Carcinogenesis, 2017, v. 56, n. 2, p. 550, doi. 10.1002/mc.22516
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- Article
Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.723162
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- Publication type:
- Article
A Near-Chromosome Level Genome Assembly of Anopheles stephensi.
- Published in:
- Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.565626
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- Publication type:
- Article
Whole-exome sequencing of Indian prostate cancer reveals a novel therapeutic target: POLQ.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 6, p. 2451, doi. 10.1007/s00432-022-04111-0
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- Publication type:
- Article
Acute toxicity analysis of Disarib, an inhibitor of BCL2.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72058-8
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- Publication type:
- Article
Vitamin B<sub>6,</sub> B<sub>12</sub> and folate modulate deregulated pathways and protein aggregation in yeast model of Huntington disease.
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- 3 Biotech, 2023, v. 13, n. 3, p. 1, doi. 10.1007/s13205-023-03525-y
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- Article
Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma.
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- Nucleic Acids Research, 2011, v. 39, n. 3, p. 936, doi. 10.1093/nar/gkq824
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- Article
Integration of exome-seq and mRNA-seq using DawnRank, identified genes involved in innate immunity as drivers of breast cancer in the Indian cohort.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.16033
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- Article
A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.
- Published in:
- Scientific Reports, 2016, p. 34653, doi. 10.1038/srep34653
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- Publication type:
- Article
Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis.
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- Scientific Reports, 2016, p. 24049, doi. 10.1038/srep24049
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- Publication type:
- Article
Extract of Vernonia condensata, Inhibits Tumor Progression and Improves Survival of Tumor-allograft Bearing Mouse.
- Published in:
- Scientific Reports, 2016, p. 23255, doi. 10.1038/srep23255
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- Article