Works by Choi, Jang Hyun

Results: 39

RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2.

Published in:

Biomedical Reports, 2018, v. 9, n. 3, p. 241, doi. 10.3892/br.2018.1119

By:

Shin, Yoonjae;
Kim, Yong Woo;
Kim, Hyemin;
Shin, Nakyoung;
Kim, Tae Sung;
Kwon, Taeg Kyu;
Choi, Jang Hyun;
Chang, Jong-Soo

Publication type:

Article

PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 343, doi. 10.3390/cells9020343

By:

Khim, Keon Woo;
Choi, Sun Sil;
Jang, Hyun-Jun;
Lee, Yo Han;
Lee, Eujin;
Hyun, Ji-Min;
Eom, Hye-Jin;
Yoon, Sora;
Choi, Jeong-Won;
Park, Tae-Eun;
Nam, Dougu;
Choi, Jang Hyun

Publication type:

Article

The Small-Molecule Wnt Inhibitor ICG-001 Efficiently Inhibits Colorectal Cancer Stemness and Metastasis by Suppressing MEIS1 Expression.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13413, doi. 10.3390/ijms222413413

By:

Choi, Jang-Hyun;
Jang, Tae-Young;
Jeon, So-El;
Kim, Jee-Heun;
Lee, Choong-Jae;
Yun, Hyeon-Ji;
Jung, Ji-Youn;
Park, So-Yeon;
Nam, Jeong-Seok

Publication type:

Article

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy.

Published in:

Experimental & Molecular Medicine EMM, 2023, v. 55, n. 8, p. 1720, doi. 10.1038/s12276-023-01047-4

By:

Jang, Hyun-Jun;
Lee, Yo Han;
Dao, Tam;
Jo, Yunju;
Khim, Keon Woo;
Eom, Hye-jin;
Lee, Ju Eun;
Song, Yi Jin;
Choi, Sun Sil;
Park, Kieun;
Ji, Haneul;
Chae, Young Chan;
Myung, Kyungjae;
Kim, Hongtae;
Ryu, Dongryeol;
Park, Neung Hwa;
Park, Sung Ho;
Choi, Jang Hyun

Publication type:

Article

Thrap3 promotes R-loop resolution via interaction with methylated DDX5.

Published in:

Experimental & Molecular Medicine EMM, 2021, v. 53, n. 10, p. 1602, doi. 10.1038/s12276-021-00689-6

By:

Kang, Hyun Je;
Eom, Hye-jin;
Kim, Hongtae;
Myung, Kyungjae;
Kwon, Hyug Moo;
Choi, Jang Hyun

Publication type:

Article

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis.

Published in:

Experimental & Molecular Medicine EMM, 2020, v. 52, n. 6, p. 940, doi. 10.1038/s12276-020-0448-3

By:

Choi, Sun Sil;
Lee, Sang Kwon;
Kim, Joong Kwan;
Park, Hye-Kyung;
Lee, Eujin;
Jang, Jinho;
Lee, Yo Han;
Khim, Keon Woo;
Hyun, Ji-Min;
Eom, Hye-jin;
Lee, Semin;
Kang, Byuong Heon;
Chae, Young Chan;
Myung, Kyungjae;
Myung, Seung-Jae;
Park, Chan Young;
Choi, Jang Hyun

Publication type:

Article

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.70472

By:

Yo Han Lee;
Hyun-Jun Jang;
Sounkou Kim;
Sun Sil Choi;
Keon Woo Khim;
Hye-jin Eom;
Jimin Hyun;
Kyeong Jin Shin;
Young Chan Chae;
Hongtae Kim;
Jiyoung Park;
Neung Hwa Park;
Chang-Yun Woo;
Chung Hwan Hong;
Eun Hee Koh;
Dougu Nam;
Jang Hyun Choi

Publication type:

Article

The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1405-7

By:

Park, So-Yeon;
Lee, Choong-Jae;
Choi, Jang-Hyun;
Kim, Jee-Heun;
Kim, Ji-Won;
Kim, Ji-Young;
Nam, Jeong-Seok

Publication type:

Article

Targeting Cancer Stem Cells in Triple-Negative Breast Cancer.

Published in:

Cancers, 2019, v. 11, n. 7, p. 965, doi. 10.3390/cancers11070965

By:

Park, So-Yeon;
Choi, Jang-Hyun;
Nam, Jeong-Seok

Publication type:

Article

C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 8, p. 1, doi. 10.1128/MCB.01447-12

By:

Koh, Ara;
Mi Nam Lee;
Yong Ryoul Yang;
Heeyoon Jeong;
Jaewang Ghim;
Jeongeun Noh;
Jaeyoon Kim;
Dongryeol Ryu;
Park, Sehoon;
Parkyong Song;
Seung-Hoi Koo;
Leslie, Nick R.;
Berggren, Per-Olof;
Jang Hyun Choi;
Pann-Ghill Suh;
Sung Ho Ryu

Publication type:

Article

O-GlcNAcase is essential for embryonic development and maintenance of genomic stability.

Published in:

Aging Cell, 2012, v. 11, n. 3, p. 439, doi. 10.1111/j.1474-9726.2012.00801.x

By:

Yang, Yong Ryoul;
Song, Minseok;
Lee, Ho;
Jeon, Yoon;
Choi, Eun-Jeong;
Jang, Hyun-Jun;
Moon, Hyo Youl;
Byun, Ha-Young;
Kim, Eung-Kyun;
Kim, Dae Hyun;
Lee, Mi Nam;
Koh, Ara;
Ghim, Jaewang;
Choi, Jang Hyun;
Lee-Kwon, Whaseon;
Kim, Kyong Tai;
Ryu, Sung Ho;
Suh, Pann-Ghill

Publication type:

Article

DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis.

Published in:

Theranostics, 2022, v. 12, n. 12, p. 5258, doi. 10.7150/thno.72037

By:

Jee-Heun Kim;
So-Yeon Park;
So-El Jeon;
Jang-Hyun Choi;
Choong-Jae Lee;
Tae-Young Jang;
Hyeon-Ji Yun;
Yuno Lee;
Pilho Kim;
Sang Hee Cho;
Ji Shin Lee;
Jeong-Seok Nam

Publication type:

Article

Dysadherin awakens mechanical forces and promotes colorectal cancer progression.

Published in:

Theranostics, 2022, v. 12, n. 9, p. 4399, doi. 10.7150/thno.72354

By:

So-Yeon Park;
Choong-Jae Lee;
Jang-Hyun Choi;
Jee-Heun Kim;
Won-Jae Lee;
Tae-Young Jang;
So-El Jeon;
Jae-Hyun Kim;
Sang-Hee Cho;
Ji-Shin Lee;
Jeong-Seok Nam

Publication type:

Article

Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells.

Published in:

Theranostics, 2021, v. 11, n. 18, p. 8755, doi. 10.7150/thno.63446

By:

So-Yeon Park;
Ji-Young Kim;
Gyu-Beom Jang;
Jang-Hyun Choi;
Jee-Heun Kim;
Choong-Jae Lee;
Sunjae Lee;
Jeong-Heum Baek;
Kwan-Kyu Park;
Jin-Man Kim;
Hee Jin Chang;
Nam-Chul Cho;
Jeong-Seok Nam

Publication type:

Article

Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation.

Published in:

Nutrients, 2020, v. 12, n. 3, p. 773, doi. 10.3390/nu12030773

By:

Lee, Jae Min;
Choi, Sun Sil;
Park, Mi Hyeon;
Jang, Hyunduk;
Lee, Yo Han;
Khim, Keon Woo;
Oh, Sei Ryang;
Park, Jiyoung;
Ryu, Hyung Won;
Choi, Jang Hyun

Publication type:

Article

Potential Inhibition of PDK1/Akt Signaling by Phenothiazines Suppresses Cancer Cell Proliferation and Survival.

Published in:

Annals of the New York Academy of Sciences, 2008, v. 1138, p. 393, doi. 10.1196/annals.1414.041

By:

Choi, Jang Hyun;
Yang, Yong Ryoul;
Lee, Seul Ki;
Kim, Sun‐Hee;
Kim, Yun‐Hee;
Cha, Joo‐Young;
Oh, Se‐Woong;
Ha, Jong‐Ryul;
Ryu, Sung Ho;
Suh, Pann‐Ghill

Publication type:

Article

Rücktitelbild: Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy (Angew. Chem. 20/2014).

Published in:

Angewandte Chemie, 2014, v. 126, n. 20, p. 5316, doi. 10.1002/ange.201401129

By:

Koh, Minseob;
Park, Jongmin;
Koo, Ja Young;
Lim, Donghyun;
Cha, Mi Young;
Jo, Ala;
Choi, Jang Hyun;
Park, Seung Bum

Publication type:

Article

Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy.

Published in:

Angewandte Chemie, 2014, v. 126, n. 20, p. 5202, doi. 10.1002/ange.201310618

By:

Koh, Minseob;
Park, Jongmin;
Koo, Ja Young;
Lim, Donghyun;
Cha, Mi Young;
Jo, Ala;
Choi, Jang Hyun;
Park, Seung Bum

Publication type:

Article

Preparation of micron-size monodisperse poly(methyl methacrylate) particles using poly(2-oxazoline) macromonomer.

Published in:

Polymer International, 1994, v. 30, n. 2, p. 265, doi. 10.1002/pi.4990300221

By:

Kobayashi, Shiro;
Uyama, Hiroshi;
Choi, Jang Hyun;
Matsumoto, Yasuhiro

Publication type:

Article

Rational Design and Synthesis of Reversible Covalent PPARγ Antagonistic Ligands Inhibiting Ser273 Phosphorylation.

Published in:

Asian Journal of Organic Chemistry, 2019, v. 8, n. 9, p. 1698, doi. 10.1002/ajoc.201800668

By:

Kim, Hyunsoo;
Jo, Ala;
Choi, Sun‐Sil;
Nam, Hyunsung;
Byun, Wan Gi;
Bae, Hwan;
Choi, Jang Hyun;
Park, Seung Bum

Publication type:

Article

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 15, p. 7936, doi. 10.1093/nar/gkad543

By:

Kang, Yujin;
Han, Ye Gi;
Khim, Keon Woo;
Choi, Woo Gyun;
Ju, Min Kyung;
Park, Kibeom;
Shin, Kyeong Jin;
Chae, Young Chan;
Choi, Jang Hyun;
Kim, Hongtae;
Lee, Ja Yil

Publication type:

Article

NSMF promotes the replication stress-induced DNA damage response for genome maintenance.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 10, p. 5605, doi. 10.1093/nar/gkab311

By:

Ju, Min Kyung;
Shin, Kyeong Jin;
Lee, Joo Rak;
Khim, Keon Woo;
A. Lee, Eun;
Ra, Jae Sun;
Kim, Byung-Gyu;
Jo, Han-seul;
Yoon, Jong Hyuk;
Kim, Tae Moon;
Myung, Kyungjae;
Choi, Jang Hyun;
Kim, Hongtae;
Chae, Young Chan

Publication type:

Article

Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer.

Published in:

FASEB Journal, 2020, v. 34, n. 1, p. 1270, doi. 10.1096/fj.201901437R

By:

Jang, Hyun‐Jun;
Lim, Seyoung;
Kim, Jung‐Min;
Yoon, Sora;
Lee, Chae Young;
Hwang, Hyeon‐Jeong;
Shin, Jeong Woo;
Shin, Kyeong Jin;
Kim, Hye Yun;
Park, Kwang Il;
Nam, Dougu;
Lee, Ja Yil;
Yea, Kyungmoo;
Hirabayashi, Yoshio;
Lee, Yu Jin;
Chae, Young Chan;
Suh, Pann‐Ghill;
Choi, Jang Hyun

Publication type:

Article

Phospholipase C-β1 potentiates glucose-stimulated insulin secretion.

Published in:

FASEB Journal, 2019, v. 33, n. 10, p. 10668, doi. 10.1096/fj.201802732RR

By:

Hyeon-Jeong Hwang;
Yong Ryoul Yang;
Hye Yun Kim;
Yoonji Choi;
Kyoung-Su Park;
Ho Lee;
Ji Su Ma;
Masahiro Yamamoto;
Jaeyoon Kim;
Young Chan Chae;
Jang Hyun Choi;
Lucio Cocco;
Berggren, Per-Olof;
Hyun-Jun Jang;
Pann-Ghill Suh

Publication type:

Article

PPARγ Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue.

Published in:

2016

By:

Sun-Sil Choi;
Eun-Sun Kim;
Ji-Eun Jung;
Marciano, David P.;
Ala Jo;
Ja Young Koo;
Soo Youn Choi;
Yong Ryoul Yang;
Hyun-Jun Jang;
Eung-Kyun Kim;
Jiyoung Park;
Hyug Moo Kwon;
In Hee Lee;
Seung Bum Park;
Kyung-Jae Myung;
Suh, Pann-Ghill;
Griffin, Patrick R.;
Jang Hyun Choi;
Choi, Sun-Sil;
Kim, Eun-Sun

Publication type:

journal article

Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acid.

Published in:

Journal of Neurochemistry, 2006, v. 99, n. 2, p. 458, doi. 10.1111/j.1471-4159.2006.04108.x

By:

Kim, Hyeon Soo;
Song, Minseok;
Yumkham, Sanatombi;
Choi, Jang Hyun;
Lee, Taehoon;
Kwon, Joseph;
Lee, Sung Jae;
Kim, Jong-In;
Lee, Kang-Woo;
Han, Pyung-Lim;
Shin, Seung Woo;
Baik, Ja-Hyun;
Kim, Yong Sik;
Ryu, Sung Ho;
Suh, Pann-Ghill

Publication type:

Article

Zafirlukast promotes insulin secretion by increasing calcium influx through L‐type calcium channels.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 11, p. 8701, doi. 10.1002/jcp.26750

By:

Hwang, Hyeon‐Jeong;
Park, Kyoung‐Su;
Choi, Jang Hyun;
Cocco, Lucio;
Jang, Hyun‐Jun;
Suh, Pann‐Ghill

Publication type:

Article

Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells.

Published in:

Clinical & Translational Medicine, 2021, v. 11, n. 11, p. 1, doi. 10.1002/ctm2.552

By:

Park, So‐Yeon;
Kim, Jee‐Heun;
Choi, Jang‐Hyun;
Lee, Choong‐Jae;
Lee, Won‐Jae;
Park, Sehoon;
Park, Zee‐Yong;
Baek, Jeong‐Heum;
Nam, Jeong‐Seok

Publication type:

Article

Phospholipase Cγ1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B.

Published in:

Nature Cell Biology, 2006, v. 8, n. 12, p. 1389, doi. 10.1038/ncb1509

By:

Jang Hyun Choi;
Hyeon Soo Kim;
Sun-Hee Kim;
Yong Ryoul Yang;
Yun Soo Bae;
Jong-Soo Chang;
Moo Kwon, H.;
Sung Ho Ryu;
Pann-Ghill Suh

Publication type:

Article

Boström et al. reply.

Published in:

Nature, 2012, v. 488, n. 7413, p. E10, doi. 10.1038/nature11365

By:

Boström, Pontus;
Wu, Jun;
Jedrychowski, Mark P.;
Korde, Anisha;
Ye, Li;
Lo, James C.;
Rasbach, Kyle A.;
Boström, Elisabeth Almer;
Choi, Jang Hyun;
Long, Jonathan Z.;
Kajimura, Shingo;
Zingaretti, Maria Cristina;
Vind, Birgitte F.;
Tu, Hua;
Cinti, Saverio;
Højlund, Kurt;
Gygi, Steven P.;
Spiegelman, Bruce M.

Publication type:

Article

A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.

Published in:

Nature, 2012, v. 481, n. 7382, p. 463, doi. 10.1038/nature10777

By:

Boström, Pontus;
Wu, Jun;
Jedrychowski, Mark P.;
Korde, Anisha;
Ye, Li;
Lo, James C.;
Rasbach, Kyle A.;
Boström, Elisabeth Almer;
Choi, Jang Hyun;
Long, Jonathan Z.;
Kajimura, Shingo;
Zingaretti, Maria Cristina;
Vind, Birgitte F.;
Tu, Hua;
Cinti, Saverio;
Højlund, Kurt;
Gygi, Steven P.;
Spiegelman, Bruce M.

Publication type:

Article

Antidiabetic actions of a non-agonist PPAR? ligand blocking Cdk5-mediated phosphorylation.

Published in:

Nature, 2011, v. 477, n. 7365, p. 477, doi. 10.1038/nature10383

By:

Jang Hyun Choi;
Banks, Alexander S.;
Kamenecka, Theodore M.;
Busby, Scott A.;
Chalmers, Michael J.;
Kumar, Naresh;
Kuruvilla, Dana S.;
Youseung Shin;
Yuanjun He;
Bruning, John B.;
Marciano, David P.;
Cameron, Michael D.;
Laznik, Dina;
Jurczak, Michael J.;
Schürer, Stephan C.;
Vidović, Dušica;
Shulman, Gerald I.;
Spiegelman, Bruce M.;
Griffin, Patrick R.

Publication type:

Article

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5.

Published in:

Nature, 2010, v. 466, n. 7305, p. 451, doi. 10.1038/nature09291

By:

Jang Hyun Choi;
Banks, Alexander S.;
Estall, Jennifer L.;
Kajimura, Shingo;
Boström, Pontus;
Laznik, Dina;
Ruas, Jorge L.;
Chalmers, Michael J.;
Kamenecka, Theodore M.;
Blüher, Matthias;
Griffin, Patrick R.;
Spiegelman, Bruce M.

Publication type:

Article

Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors.

Published in:

NAR Cancer, 2023, v. 5, n. 3, p. 1, doi. 10.1093/narcan/zcad042

By:

Minwoo Wie;
Keon Woo Khim;
Groehler IV, Arnold S.;
Soomin Heo;
Junhyeok Woo;
Kook Son;
Lee, Eun A.;
Jae Sun Ra;
Sung You Hong;
Schärer, Orlando D.;
Jang Hyun Choi;
Kyungjae Myung

Publication type:

Article

Comparison of Enhanced Photocatalytic Degradation Efficiency and Toxicity Evaluations of CeO2 Nanoparticles Synthesized Through Double-Modulation.

Published in:

Nanomaterials (2079-4991), 2020, v. 10, n. 8, p. 1543, doi. 10.3390/nano10081543

By:

Choi, Jang Hyun;
Hong, Jung-A;
Son, Ye Rim;
Wang, Jian;
Kim, Hyun Sung;
Lee, Hansol;
Lee, Hangil

Publication type:

Article

Back Cover: Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy (Angew. Chem. Int. Ed. 20/2014).

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 20, p. 5216, doi. 10.1002/anie.201401129

By:

Koh, Minseob;
Park, Jongmin;
Koo, Ja Young;
Lim, Donghyun;
Cha, Mi Young;
Jo, Ala;
Choi, Jang Hyun;
Park, Seung Bum

Publication type:

Article

Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 20, p. 5102, doi. 10.1002/anie.201310618

By:

Koh, Minseob;
Park, Jongmin;
Koo, Ja Young;
Lim, Donghyun;
Cha, Mi Young;
Jo, Ala;
Choi, Jang Hyun;
Park, Seung Bum

Publication type:

Article

COL6A3‐derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease.

Published in:

Journal of Pathology, 2019, v. 247, n. 1, p. 99, doi. 10.1002/path.5172

By:

Lee, Changhu;
Kim, Min;
Lee, Jun Ho;
Oh, Jiyoung;
Shin, Hyun‐Hee;
Lee, Sang Min;
Scherer, Philipp E;
Kwon, Hyug Moo;
Choi, Jang Hyun;
Park, Jiyoung

Publication type:

Article

The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ.

Published in:

Experimental & Molecular Medicine EMM, 2018, v. 50, n. 10, p. 1, doi. 10.1038/s12276-018-0162-6

By:

Lee, Jae Min;
Choi, Sun Sil;
Lee, Yo Han;
Khim, Keon Woo;
Yoon, Sora;
Kim, Byung-gyu;
Nam, Dougu;
Suh, Pann-Ghill;
Myung, Kyungjae;
Choi, Jang Hyun

Publication type:

Article