Works by Chiu, Philip C. N.

Results: 32

Application of a JEG-3 organoid model to study HLA-G function in the trophoblast.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1130308

By:

Bai-Mei Zhuang;
Dan-Dan Cao;
Xiao-Feng Liu;
Li Wang;
Xiao-Li Lin;
Yong-Gang Duan;
Cheuk-Lun Lee;
Chiu, Philip C. N.;
Yeung, William S. B.;
Yuan-Qing Yao

Publication type:

Article

The role of spermatozoa-zona pellucida interaction in selecting fertilization-competent spermatozoa in humans.

Published in:

Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1135973

By:

Leung, Erica T. Y.;
Lee, Brayden K. M.;
Cheuk-Lun Lee;
Xinyi Tian;
Lam, Kevin K. W.;
Li, Raymond H. W.;
Ng, Ernest H. Y.;
Yeung, William S. B.;
Jian-Ping Ou;
Chiu, Philip C. N.

Publication type:

Article

Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes.

Published in:

Journal of Nanobiotechnology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12951-022-01283-2

By:

Bai, Kunfeng;
Lee, Cheuk-Lun;
Liu, Xiaofeng;
Li, Jianlin;
Cao, Dandan;
Zhang, Li;
Hu, Duanlin;
Li, Hong;
Hou, Yanqing;
Xu, Yue;
Kan, Anita S. Y.;
Cheung, Ka-Wang;
Ng, Ernest H. Y.;
Yeung, William S. B.;
Chiu, Philip C. N.

Publication type:

Article

The functional roles of protein glycosylation in human maternal–fetal crosstalk.

Published in:

Human Reproduction Update, 2024, v. 30, n. 1, p. 81, doi. 10.1093/humupd/dmad024

By:

Zhong, Jiangming;
Li, Jianlin;
Burton, Graham J;
Koistinen, Hannu;
Cheung, Ka Wang;
Ng, Ernest H Y;
Yao, Yuanqing;
Yeung, William S B;
Lee, Cheuk-Lun;
Chiu, Philip C N

Publication type:

Article

The regulatory role of placental extracellular vesicle on trophoblast and endothelial cell functions.

Published in:

Frontiers in Cell & Developmental Biology, 2025, p. 1, doi. 10.3389/fcell.2025.1528714

By:

Bai, Kunfeng;
Li, Xintong;
Guo, Yanjie;
Shang, Ye;
Lin, Leqian;
Chiu, Philip C. N.;
Lee, Cheuk-Lun

Publication type:

Article

The role of galectin-3 in spermatozoa-zona pellucida binding and its association with fertilization in vitro.

Published in:

Molecular Human Reproduction, 2019, v. 25, n. 8, p. 458, doi. 10.1093/molehr/gaz030

By:

Mei, Si;
Chen, Panyu;
Lee, Cheuk-Lun;
Zhao, Weie;
Wang, Ying;
Lam, Kevin K W;
Ho, Pak-Chung;
Yeung, William S B;
Fang, Cong;
Chiu, Philip C N

Publication type:

Article

Sperm fucosyltransferase-5 mediates spermatozoa-oviductal epithelial cell interaction to protect human spermatozoa from oxidative damage.

Published in:

Molecular Human Reproduction, 2015, v. 21, n. 6, p. 516, doi. 10.1093/molehr/gav015

By:

Venus Wenxin Huang;
Cheuk-Lun Lee;
Yin-Lau Lee;
Lam, Kevin K. W.;
Ko, Jennifer K. Y.;
Yeung, William S. B.;
Pak-Chung Ho;
Chiu, Philip C. N.

Publication type:

Article

Placenta exosomal miRNA-30d-5p facilitates decidual macrophage polarization by targeting HDAC9.

Published in:

Journal of Leukocyte Biology, 2023, v. 113, n. 5, p. 434, doi. 10.1093/jleuko/qiad022

By:

Bai, Kunfeng;
Li, Jianlin;
Lin, Leqian;
Zhang, Qingqing;
Zhong, Jiangming;
Liu, Xiaofeng;
Cao, Dandan;
Duan, Yong-Gang;
Yao, Yuanqing;
Li, Raymond H W;
Cheung, Ka-Wang;
Yeung, William S B;
Chiu, Philip C N;
Lee, Cheuk-Lun

Publication type:

Article

Platelet‐activating factor induces acrosome reaction via the activation of extracellular signal‐regulated kinase in human spermatozoa.

Published in:

Andrologia, 2020, v. 52, n. 5, p. 1, doi. 10.1111/and.13565

By:

Wu, Haitao;
Gao, Jing;
Wang, Xia;
Leung, Tsz Ying;
Duan, Yong‐Gang;
Chiu, Philip C. N.

Publication type:

Article

Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization.

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 2, p. 791, doi. 10.1007/s00216-010-3991-2

By:

Lam, Maggie P. Y.;
Siu, S. O.;
Lau, Edward;
Mao, Xiuli;
Sun, H. Z.;
Chiu, Philip C. N.;
Yeung, William S. B.;
Cox, David M.;
Chu, Ivan K.

Publication type:

Article

Computational approaches for predicting variant impact: An overview from resources, principles to applications.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.981005

By:

Ye Liu;
Yeung, William S. B.;
Chiu, Philip C. N.;
Cao, Dandan

Publication type:

Article

Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation.

Published in:

Reproductive Biology & Endocrinology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12958-022-00973-8

By:

Li, Xintong;
Kodithuwakku, Suranga P.;
Chan, Rachel W. S.;
Yeung, William S. B.;
Yao, Yuanqing;
Ng, Ernest H. Y.;
Chiu, Philip C. N.;
Lee, Cheuk-Lun

Publication type:

Article

B cells: roles in physiology and pathology of pregnancy.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1456171

By:

Jin-Chuan Liu;
Qunxiong Zeng;
Yong-Gang Duan;
Yeung, William S. B.;
H. W. Li, Raymond;
Ng, Ernest H. Y.;
Ka-Wang Cheung;
Qingqing Zhang;
Chiu, Philip C. N.

Publication type:

Article

Interleukin 6 at menstruation promotes the proliferation and self-renewal of endometrial mesenchymal stromal/stem cells through the WNT/β-catenin signaling pathway.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1378863

By:

Tianqi Li;
Li, Raymond H. W.;
Ng, Ernest H. Y.;
Yeung, William S. B.;
Chiu, Philip C. N.;
Chan, Rachel W. S.

Publication type:

Article

Transcriptomic analysis of mid‐secretory endometrium reveals essential immune factors associated with pregnancy after single euploid blastocyst transfer.

Published in:

American Journal of Reproductive Immunology, 2023, v. 89, n. 3, p. 1, doi. 10.1111/aji.13672

By:

Cheng, Yanfei;
Wang, Hui;
Shang, Jin;
Wang, Jue;
Yin, Jingwen;
Zhang, Jinning;
Guo, Xinmeng;
Wang, Sidong;
Duan, Yong‐Gang;
Lee, Cheuk‐Lun;
Chiu, Philip C. N.;
Zhang, Jian;
Yeung, William S. B.;
Cao, Dandan;
Yao, Yuanqing

Publication type:

Article

Alteration of the immune cell profiles in the pathophysiology of tubal ectopic pregnancy.

Published in:

American Journal of Reproductive Immunology, 2019, v. 81, n. 4, p. N.PAG, doi. 10.1111/aji.13093

By:

Wang, Xia;
Lee, Cheuk‐Lun;
Li, Raymond H. W.;
Vijayan, Madhavi;
Duan, Yong‐Gang;
Yeung, William S. B.;
Zhang, Yuanzhen;
Chiu, Philip C. N.

Publication type:

Article

The Pleiotropic Effect of Glycodelin-A in Early Pregnancy.

Published in:

American Journal of Reproductive Immunology, 2016, v. 75, n. 3, p. 290, doi. 10.1111/aji.12471

By:

Vijayan, Madhavi;
Lee, Cheuk-Lun;
Ng, Ernest H. Y.;
Yeung, William S. B.;
Chiu, Philip C. N.;
Lam, Kevin K. W.;
Koistinen, Hannu;
Seppala, Markku

Publication type:

Article

Placenta-Derived Exosomes as a Modulator in Maternal Immune Tolerance During Pregnancy.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.671093

By:

Bai, Kunfeng;
Li, Xintong;
Zhong, Jiangming;
Ng, Ernest H. Y.;
Yeung, William S.B.;
Lee, Cheuk-Lun;
Chiu, Philip C. N.

Publication type:

Article

Glycosylation failure extends to glycoproteins in gestational diabetes mellitus: evidence from reduced α2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A.

Published in:

2011

By:

Lee CL;
Chiu PC;
Pang PC;
Chu IK;
Lee KF;
Koistinen R;
Koistinen H;
Seppälä M;
Morris HR;
Tissot B;
Panico M;
Dell A;
Yeung WS;
Lee, Cheuk-Lun;
Chiu, Philip C N;
Pang, Poh-Choo;
Chu, Ivan K;
Lee, Kai-Fai;
Koistinen, Riitta;
Koistinen, Hannu

Publication type:

journal article

MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-25

By:

Pang, Ronald T. K.;
Leung, Carmen O. N.;
Cheuk-Lun Lee;
Lam, Kevin K. W.;
Tian-Min Ye;
Chiu, Philip C. N.;
Yeung, William S. B.

Publication type:

Article

Long-read sequencing on the SMRT platform enables efficient haplotype linkage analysis in preimplantation genetic testing for β-thalassemia.

Published in:

Journal of Assisted Reproduction & Genetics, 2022, v. 39, n. 3, p. 739, doi. 10.1007/s10815-022-02415-1

By:

Wu, Haitao;
Chen, Dongjia;
Zhao, Qiang;
Shen, Xiaoting;
Liao, Yongbin;
Li, Ping;
Chiu, Philip C. N.;
Zhou, Canquan

Publication type:

Article

Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility.

Published in:

Molecular Reproduction & Development, 2014, v. 81, n. 6, p. 482, doi. 10.1002/mrd.22331

By:

Lee, Cheuk‐Lun;
Li, Kunming;
Lam, Kevin K. W.;
Ng, Ernest H. Y.;
Koistinen, Hannu;
Seppälä, Markku;
Yeung, William S. B.;
Chiu, Philip C. N.

Publication type:

Article

Glycodelin-A stimulates the conversion of human peripheral blood CD16-CD56bright NK cell to a decidual NK cell-like phenotype.

Published in:

2019

By:

Lee, Cheuk-Lun;
Vijayan, Madhavi;
Wang, Xia;
Lam, Kevin K W;
Koistinen, Hannu;
Seppala, Markku;
Li, Raymond H W;
Ng, Ernest H Y;
Yeung, William S B;
Chiu, Philip C N

Publication type:

journal article

The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding.

Published in:

2017

By:

Chi-Wai Wong;
Lam, Kevin K. W.;
Cheuk-Lun Lee;
Yeung, William S. B.;
Zhao, Wei E.;
Pak-Chung Ho;
Jian-Ping Ou;
Chiu, Philip C. N.;
Wong, Chi-Wai;
Lee, Cheuk-Lun;
Ho, Pak-Chung;
Ou, Jian-Ping

Publication type:

journal article

Soluble human leukocyte antigen G5 polarizes differentiation of macrophages toward a decidual macrophage-like phenotype.

Published in:

2015

By:

Cheuk-Lun Lee;
Yi Fan Guo;
Kam-Hei So;
Vijayan, Madhavi;
Yue Guo;
Wong, Vera H. H.;
Yuan Qing Yao;
Kai-Fai Lee;
Chiu, Philip C. N.;
Yeung, William S. B.;
Lee, Cheuk-Lun;
Guo, YiFan;
So, Kam-Hei;
Guo, Yue;
Yao, YuanQing;
Lee, Kai-Fai

Publication type:

journal article

Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx.

Published in:

2010

By:

Chiu, Philip C. N.;
Wong, Ben S. T.;
Cheuk-Lun Lee;
Lam, Kevin K. W.;
Man-Kin Chung;
Kai-Fai Lee;
Koistinen, Riitta;
Koistinen, Hannu;
Gupta, Satish K.;
Seppälä, Markku;
Yeung, William S. B.;
Lee, Cheuk-Lun;
Chung, Man-Kin;
Lee, Kai-Fai;
Seppälä, Markku

Publication type:

journal article

Cumulus-associated alpha2-macroglobulin derivative retains proconceptive glycodelin-C in the human cumulus matrix.

Published in:

2009

By:

Man-Kin Chung;
Chiu, Philip C. N.;
Cheuk-Lun Lee;
Pang, Ronald T. K.;
Ng, E. H. Y.;
Kai-Fai Lee;
Koistinen, Riitta;
Koistinen, Hannu;
Seppala, Markku;
Yeung, William S. B.;
Chung, Man-Kin;
Lee, Cheuk-Lun;
Lee, Kai-Fai

Publication type:

journal article

Glycodelin-A as a modulator of trophoblast invasion.

Published in:

2009

By:

Lam, Kevin K. W.;
Chiu, Philip C. N.;
Chung, Man-Kin;
Lee, Cheuk-Lun;
Lee, Kai-Fai;
Koistinen, Riitta;
Koistinen, Hannu;
Seppala, Markku;
Ho, Pak-Chung;
Yeung, William S. B.

Publication type:

journal article

Annexin A2 Acts as an Adhesion Molecule on the Endometrial Epithelium during Implantation in Mice.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139506

By:

Wang, Bing;
Ye, Tian-Min;
Lee, Kai-Fai;
Chiu, Philip C. N.;
Pang, Ronald T. K.;
Ng, Ernest H. Y.;
Yeung, William S. B.

Publication type:

Article

MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.

Published in:

Carcinogenesis, 2010, v. 31, n. 6, p. 1037, doi. 10.1093/carcin/bgq066

By:

Pang, Ronald T. K.;
Leung, Carmen O. N.;
Tian-Min Ye;
Weimin Liu;
Chiu, Philip C. N.;
Lam, Kevin K. W.;
Kai-Fai Lee;
Yeung, William S. B.

Publication type:

Article

Sialyl Lewis<sup>x</sup>-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10334-6

By:

Li, Shan-Shan;
Ip, Carman K. M.;
Tang, Matthew Y. H.;
Tang, Maggie K. S.;
Tong, Yin;
Zhang, Jiangwen;
Hassan, Ayon Ahmed;
Mak, Abby S. C.;
Yung, Susan;
Chan, Tak-Mao;
Ip, Philip P.;
Lee, Cheuk Lun;
Chiu, Philip C. N.;
Lee, Leo Tsz On;
Lai, Hung-Cheng;
Zeng, Jin-Zhang;
Shum, Ho Cheung;
Wong, Alice S. T.

Publication type:

Article

The application of late amniocentesis: a retrospective study in a tertiary fetal medicine center in China.

Published in:

2021

By:

Li, Yingting;
Yan, Huanchen;
Chen, Jingsi;
Chen, Fei;
Jian, Wei;
Wang, Jiayan;
Ye, Xiaoqing;
Li, Yufan;
Li, Nan;
Chiu, Philip C. N.;
Chen, Min

Publication type:

journal article