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Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks.
- Published in:
- Proteomics, 2022, v. 22, n. 19, p. 1, doi. 10.1002/pmic.202100247
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- Publication type:
- Article
Mouse model of Alzheimer's disease demonstrates differential effects of early disease pathology on various brain regions.
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- Proteomics, 2021, v. 21, n. 7/8, p. 1, doi. 10.1002/pmic.202000213
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- Publication type:
- Article
Unravelling the Therapeutic Potential of Nano-Delivered Functional Foods in Chronic Respiratory Diseases.
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- Nutrients, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/nu14183828
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- Publication type:
- Article
Interaction studies of Alzheimer's Cathepsin B protein with inhibitors in presence and absence of water.
- Published in:
- 2014
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- Publication type:
- Abstract
Amyloid β Induces Early Changes in the Ribosomal Machinery, Cytoskeletal Organization and Oxidative Phosphorylation in Retinal Photoreceptor Cells.
- Published in:
- Frontiers in Molecular Neuroscience, 2019, p. 1, doi. 10.3389/fnmol.2019.00024
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- Publication type:
- Article
The role of myelin in neurodegeneration: implications for drug targets and neuroprotection strategies.
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- Reviews in the Neurosciences, 2024, v. 35, n. 3, p. 271, doi. 10.1515/revneuro-2023-0081
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- Publication type:
- Article
Retinal proteomics of experimental glaucoma model reveal intraocular pressure‐induced mediators of neurodegenerative changes.
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- Journal of Cellular Biochemistry, 2020, v. 121, n. 12, p. 4931, doi. 10.1002/jcb.29822
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- Publication type:
- Article
Retinal proteomics of experimental glaucoma model reveal intraocular pressure‐induced mediators of neurodegenerative changes.
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- Journal of Cellular Biochemistry, 2020, v. 121, n. 12, p. 4931, doi. 10.1002/jcb.29822
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- Publication type:
- Article
Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand‐activated transcription factors, retinoid X receptors.
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- Journal of Cellular Biochemistry, 2019, v. 120, n. 7, p. 11745, doi. 10.1002/jcb.28455
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- Publication type:
- Article
A Proteomic View of Cellular and Molecular Effects of Cannabis.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 10, p. 1411, doi. 10.3390/biom11101411
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- Publication type:
- Article
Neuroserpin as a Neuroprotective Molecule in the Central Nervous System, Implications for Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083261
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- Publication type:
- Article
Quantitative Proteomics Reveal Region-Specific Alterations in Neuroserpin-Deficient Mouse Brain and Retina: Insights into Serpini1 Function.
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- Proteomes, 2024, v. 12, n. 1, p. 7, doi. 10.3390/proteomes12010007
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- Publication type:
- Article
Oxidative Stress Induced Dysfunction of Protein Synthesis in 661W Mice Photoreceptor Cells.
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- Proteomes, 2023, v. 11, n. 2, p. 12, doi. 10.3390/proteomes11020012
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- Publication type:
- Article
Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions.
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- Cells (2073-4409), 2022, v. 11, n. 22, p. 3665, doi. 10.3390/cells11223665
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- Publication type:
- Article
Key Genes and Biochemical Networks in Various Brain Regions Affected in Alzheimer's Disease.
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- Cells (2073-4409), 2022, v. 11, n. 6, p. 987, doi. 10.3390/cells11060987
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- Publication type:
- Article
Identification of Novel Cathepsin B Inhibitors with Implications in Alzheimer's Disease: Computational Refining and Biochemical Evaluation.
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- Cells (2073-4409), 2021, v. 10, n. 8, p. 1946, doi. 10.3390/cells10081946
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- Publication type:
- Article
Regulation of Brain-Derived Neurotrophic Factor and Growth Factor Signaling Pathways by Tyrosine Phosphatase Shp2 in the Retina: A Brief Review.
- Published in:
- Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2018.00085
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- Publication type:
- Article
Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell–cell interactions in the pathophysiology of neurological disease.
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- Cellular & Molecular Life Sciences, 2022, v. 79, n. 3, p. 1, doi. 10.1007/s00018-022-04185-6
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- Publication type:
- Article
One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina.
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- Cellular & Molecular Life Sciences, 2016, v. 73, n. 22, p. 4279, doi. 10.1007/s00018-016-2295-x
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- Publication type:
- Article
Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CL<sup>pro</sup> targeting repurposed drug candidates.
- Published in:
- 2020
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- Publication type:
- journal article
Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent manner.
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- Theranostics, 2021, v. 11, n. 13, p. 6154, doi. 10.7150/thno.55472
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- Publication type:
- Article
Loss of neuroserpin exacerbates retinal ganglion cell dysfunction in neuroserpin knockout mice following chronic increase in intraocular pressure.
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- Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.0576
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- Publication type:
- Article
Adeno‐associated virus (AAV) knock‐down of amyloid precursor protein attenuates retinal ganglion cell degeneration in experimental glaucoma.
- Published in:
- Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.0560
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- Publication type:
- Article
Relationship of APOE ε4 allele and BDNF Val66Met polymorphism to retinal structural and vascular OCTA parameters in aging cohort: Optic nerve decline and cognitive change study.
- Published in:
- Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.0326
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- Publication type:
- Article
Tau hyperphosphorylation in the retinal ganglion cells is attenuated upon silencing of SHP2 phosphatase: Molecular and cell biology: Neurodegeneration versus neuroprotection.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046753
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- Publication type:
- Article
Retinal inhibition of glycogen synthase kinase 3 beta protects against tau phosphorylation and stabilises microtubule assembly: Molecular and cell biology/neurodegeneration and neuroprotection.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046558
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- Publication type:
- Article
P3‐199: PTPN11 IS INVOLVED IN REGULATING TAU PROTEIN PHOSPHORYLATION IN THE RETINA.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1005, doi. 10.1016/j.jalz.2019.06.3228
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- Publication type:
- Article
Comprehensive Review of Methodology to Detect Reactive Oxygen Species (ROS) in Mammalian Species and Establish Its Relationship with Antioxidants and Cancer.
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- Antioxidants, 2021, v. 10, n. 1, p. 128, doi. 10.3390/antiox10010128
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- Publication type:
- Article
Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer’s disease: a meta-analysis.
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- Neural Regeneration Research, 2023, v. 18, n. 11, p. 2504, doi. 10.4103/1673-5374.371380
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- Publication type:
- Article
Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma.
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- Neural Regeneration Research, 2023, v. 18, n. 4, p. 840, doi. 10.4103/1673-5374.344952
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- Publication type:
- Article
Demyelination precedes axonal loss in the transneuronal spread of human neurodegenerative disease.
- Published in:
- 2019
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- Publication type:
- journal article
Tau modulation through AAV9 therapy augments Akt/Erk survival signalling in glaucoma mitigating the retinal degenerative phenotype.
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- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01804-0
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- Publication type:
- Article
S1PR1 signaling attenuates apoptosis of retinal ganglion cells via modulation of cJun/Bim cascade and Bad phosphorylation in a mouse model of glaucoma.
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- FASEB Journal, 2023, v. 37, n. 1, p. 1, doi. 10.1096/fj.202201346R
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- Publication type:
- Article
Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 9, p. 21087, doi. 10.3390/ijms160921087
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- Publication type:
- Article
Anti-inflammatory Effects of Siponimod in a Mouse Model of Excitotoxicity-Induced Retinal Injury.
- Published in:
- Molecular Neurobiology, 2023, v. 60, n. 12, p. 7222, doi. 10.1007/s12035-023-03535-0
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- Publication type:
- Article
Correction to: Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement.
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- 2022
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- Publication type:
- Correction Notice
Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement.
- Published in:
- Molecular Neurobiology, 2022, v. 59, n. 4, p. 2027, doi. 10.1007/s12035-021-02709-y
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- Publication type:
- Article
Caveolin-1 Ablation Imparts Partial Protection Against Inner Retinal Injury in Experimental Glaucoma and Reduces Apoptotic Activation.
- Published in:
- Molecular Neurobiology, 2020, v. 57, n. 9, p. 3759, doi. 10.1007/s12035-020-01948-9
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- Publication type:
- Article
Upregulation of Proteolytic Pathways and Altered Protein Biosynthesis Underlie Retinal Pathology in a Mouse Model of Alzheimer's Disease.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 9, p. 6017, doi. 10.1007/s12035-019-1479-4
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- Publication type:
- Article
Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 12, p. 9043, doi. 10.1007/s12035-018-1041-9
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- Publication type:
- Article
Comparative Analysis of Aducanumab, Zagotenemab and Pioglitazone as Targeted Treatment Strategies for Alzheimer's Disease.
- Published in:
- Aging & Disease, 2021, v. 12, n. 8, p. 1964, doi. 10.14336/AD.2021.0719
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- Publication type:
- Article