Works by Chiba, Peter

Results: 35

A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood-Brain Barrier with (R)-<sup>11</sup>C-Verapamil and PET.

Published in:

Journal of Nuclear Medicine, 2009, v. 50, n. 12, p. 1954, doi. 10.2967/jnumed.109.063289

By:

Wagner, Claudia C.;
Bauer, Martin;
Karch, Rudolf;
Feurstein, Thomas;
Kopp, Stephan;
Chiba, Peter;
Kletter, Kurt;
Löscher, Wolfgang;
Müller, Markus;
Zeitlinger, Markus;
Langer, Oliver

Publication type:

Article

The noncanonical nucleotide binding site 1 of the bile salt export pump is optimized for proper function of the transporter.

Published in:

Cell Biology International, 2024, v. 48, n. 5, p. 638, doi. 10.1002/cbin.12136

By:

Sohail, Imran;
Hassan, Mahmood Ul;
Schmid, Diethart;
Chiba, Peter

Publication type:

Article

The versatility of external quality assessment for the surveillance of laboratory and in vitro diagnostic performance: SARS-CoV-2 viral genome detection in Austria.

Published in:

Clinical Chemistry & Laboratory Medicine, 2021, v. 59, n. 10, p. 1735, doi. 10.1515/cclm-2021-0604

By:

Buchta, Christoph;
Camp, Jeremy V.;
Jovanovic, Jovana;
Chiba, Peter;
Puchhammer-Stöckl, Elisabeth;
Mayerhofer, Maximilian;
Plicka, Helga;
Lercher, Alexander;
Popa, Alexandra M.;
Endler, Lukas;
Bergthaler, Andreas;
Huf, Wolfgang;
Benka, Bernhard;
Delatour, Vincent;
Müller, Mathias M.;
Griesmacher, Andrea;
Aberle, Stephan W.;
Görzer, Irene

Publication type:

Article

Variability of cycle threshold values in an external quality assessment scheme for detection of the SARS-CoV-2 virus genome by RT-PCR.

Published in:

Clinical Chemistry & Laboratory Medicine, 2021, v. 59, n. 5, p. 987, doi. 10.1515/cclm-2020-1602

By:

Buchta, Christoph;
Görzer, Irene;
Chiba, Peter;
Camp, Jeremy V.;
Holzmann, Heidemarie;
Puchhammer-Stöckl, Elisabeth;
Mayerhofer, Maximilian;
Müller, Mathias M.;
Aberle, Stephan W.

Publication type:

Article

Data-driven homology modelling of P-glycoprotein in the ATP-bound state indicates flexibility of the transmembrane domains.

Published in:

FEBS Journal, 2009, v. 276, n. 4, p. 964, doi. 10.1111/j.1742-4658.2008.06832.x

By:

Stockner, Thomas;
de Vries, Sjoerd J.;
Bonvin, Alexandre M. J. J.;
Ecker, Gerhard F.;
Chiba, Peter

Publication type:

Article

Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. 5, p. 906, doi. 10.1093/jac/dkq082

By:

Janneh, Omar;
Bray, Patrick G.;
Jones, Elizabeth;
Wyen, Christoph;
Chiba, Peter;
Back, David J.;
Khoo, Saye H.

Publication type:

Article

Active transport of rhodamine 123 by the human multidrug transporter P-glycoprotein involves two independent outer gates.

Published in:

Pharmacology Research & Perspectives, 2020, v. 8, n. 2, p. 1, doi. 10.1002/prp2.572

By:

Nasim, Fauzia;
Schmid, Diethart;
Szakács, Gergely;
Sohail, Azmat;
Sitte, Harald H.;
Chiba, Peter;
Stockner, Thomas

Publication type:

Article

The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 784, doi. 10.3390/ijms22020784

By:

Sohail, Muhammad Imran;
Dönmez-Cakil, Yaprak;
Szöllősi, Dániel;
Stockner, Thomas;
Chiba, Peter

Publication type:

Article

2D- and 3D-QSAR studies of a series of benzopyranes and benzopyrano[3,4b][1,4]-oxazines as inhibitors of the multidrug transporter P-glycoprotein.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 2, p. 161, doi. 10.1007/s10822-013-9635-9

By:

Jabeen, Ishrat;
Wetwitayaklung, Penpun;
Chiba, Peter;
Pastor, Manuel;
Ecker, Gerhard

Publication type:

Article

MCASE study of the multidrug resistance reversal activity of propafenone analogs.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 5/6, p. 291, doi. 10.1023/A:1026124505322

By:

Klopman, Gilles;
Hao Zhu;
Ecker, Gerhard;
Chiba, Peter

Publication type:

Article

Simvastatin-induced compartmentalisation of doxorubicin sharpens up nuclear topoisomerase II inhibition in human rhabdomyosarcoma cells.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2013, v. 386, n. 7, p. 605, doi. 10.1007/s00210-013-0859-y

By:

Werner, Martin;
Atil, Bihter;
Sieczkowski, Evelyn;
Chiba, Peter;
Hohenegger, Martin

Publication type:

Article

Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells.

Published in:

International Journal of Cancer, 1993, v. 55, n. 1, p. 92, doi. 10.1002/ijc.2910550117

By:

Pillwein, Konrad;
Schuchter, Katharina;
Ressmann, Gabi;
Gharehbaghi, Kamran;
Knoflach, Andreas;
Cermak, Benedikt;
Jayaram, Hiremagalur N.;
Szalay, Stefan M.;
Szekeres, Thomas;
Chiba, Peter

Publication type:

Article

GM-CSF: modulation of biochemical and cytotoxic effects of tiazofurin in HL-60 cells.

Published in:

British Journal of Haematology, 1993, v. 84, n. 3, p. 552, doi. 10.1111/j.1365-2141.1993.tb03120.x

By:

Fritzer, Monika;
Gharehbaghi, Kamran;
Pillwein, Konrad;
Chiba, Peter;
Goldenberg, Hans;
Szekeres, Thomas

Publication type:

Article

Conformation of membrane-inserted P-glycoprotein.

Published in:

2010

By:

Stockner, Thomas;
Sitte, Harald H.;
Chiba, Peter

Publication type:

Abstract

Long-term regulation of ATP-binding cassette transporters on mRNA and protein level by simvastatin in human rhabdomyosarcoma and neuroblastoma cells.

Published in:

2010

By:

Atil, Bihter;
Werner, Martin;
Sieczkowski, Evelyn;
Chiba, Peter;
Hohenegger, Martin

Publication type:

Abstract

Conversion of chemical to mechanical energy by the nucleotide binding domains of ABCB1.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59403-7

By:

Szöllősi, Dániel;
Chiba, Peter;
Szakacs, Gergely;
Stockner, Thomas

Publication type:

Article

Interactions between ABC-transport proteins and the secondary Fusarium metabolites enniatin and beauvericin.

Published in:

Molecular Nutrition & Food Research, 2009, v. 53, n. 7, p. 904, doi. 10.1002/mnfr.200800384

By:

Dornetshuber, Rita;
Heffeter, Petra;
Sulyok, Michael;
Schumacher, Rainer;
Chiba, Peter;
Kopp, Stephan;
Koellensperger, Gunda;
Micksche, Michael;
Lemmens-Gruber, Rosa;
Berger, Walter

Publication type:

Article

Aluminum ions stimulate the oxidizability of low density lipoprotein by Fe 2+ : Implication in hemodialysis mediated atherogenic LDL modification.

Published in:

Free Radical Research, 2005, v. 39, n. 11, p. 1225, doi. 10.1080/10715760500306968

By:

Kapiotis, Stylianos;
Hermann, Marcela;
Exner, Markus;
Sturm, Brigitte N.;
Scheiber-Mojdehkar, Barbara;
Goldenberg, Hans;
Kopp, Stefan;
Chiba, Peter;
Gmeiner, Bernhard M.K.

Publication type:

Article

Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P-Glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP).

Published in:

ChemMedChem, 2016, v. 11, n. 12, p. 1380, doi. 10.1002/cmdc.201500592

By:

Schwarz, Theresa;
Montanari, Floriane;
Cseke, Anna;
Wlcek, Katrin;
Visvader, Lene;
Palme, Sarah;
Chiba, Peter;
Kuchler, Karl;
Urban, Ernst;
Ecker, Gerhard F.

Publication type:

Article

Multispecificity of Drug Transporters: Probing Inhibitor Selectivity for the Human Drug Efflux Transporters ABCB1 and ABCG2.

Published in:

ChemMedChem, 2007, v. 2, n. 12, p. 1783, doi. 10.1002/cmdc.200700160

By:

Cramer, Joerg;
Kopp, Stephan;
Bates, Susan E.;
Chiba, Peter;
Ecker, Gerhard F.

Publication type:

Article

Aqueous extracts of Cimicifuga racemosa and phenolcarboxylic constituents inhibit production of proinflammatory cytokines in LPS-stimulated human whole blood.

Published in:

Canadian Journal of Physiology & Pharmacology, 2009, v. 87, n. 11, p. 963, doi. 10.1139/Y09-091

By:

Schmid, Diethart;
Woehs, Florian;
Svoboda, Martin;
Thalhammer, Theresia;
Chiba, Peter;
Moeslinger, Thomas

Publication type:

Article

Exhaustive Sampling of Docking Poses Reveals Binding Hypotheses for Propafenone Type Inhibitors of P-Glycoprotein.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pcbi.1002036

By:

Klepsch, Freya;
Chiba, Peter;
Ecker, Gerhard F.

Publication type:

Article

Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones.

Published in:

Parasitology Research, 2012, v. 110, n. 6, p. 2289, doi. 10.1007/s00436-011-2763-z

By:

Ganesh, Deepa;
Fuehrer, Hans-Peter;
Starzengrüber, Peter;
Swoboda, Paul;
Khan, Wasif;
Reismann, Johannes;
Mueller, Milena;
Chiba, Peter;
Noedl, Harald

Publication type:

Article

The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle.

Published in:

FASEB Journal, 2014, v. 28, n. 10, p. 4335, doi. 10.1096/fj.13-245639

By:

Zolnerciks, Joseph K.;
Akkaya, Begum G.;
Snippe, Marjolein;
Chiba, Peter;
Seelig, Anna;
Linton, Kenneth J.

Publication type:

Article

Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.

Published in:

PLoS Genetics, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.pgen.1009016

By:

Goda, Katalin;
Dönmez-Cakil, Yaprak;
Tarapcsák, Szabolcs;
Szalóki, Gábor;
Szöllősi, Dániel;
Parveen, Zahida;
Türk, Dóra;
Szakács, Gergely;
Chiba, Peter;
Stockner, Thomas

Publication type:

Article

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells.

Published in:

Oncology Reports, 2018, v. 40, n. 2, p. 1055, doi. 10.3892/or.2018.6492

By:

Yuan, Yueling;
Chiba, Peter;
Cai, Tiange;
Callaghan, Richard;
Bai, Li;
Cole, Susan P.C.;
Cai, Yu

Publication type:

Article

An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action.

Published in:

Cellular & Molecular Life Sciences, 2012, v. 69, n. 1, p. 129, doi. 10.1007/s00018-011-0739-x

By:

Schmid, Diethart;
Stolzlechner, Michael;
Sorgner, Albin;
Bentele, Caterina;
Assinger, Alice;
Chiba, Peter;
Moeslinger, Thomas

Publication type:

Article

Characterization of a novel class of antimalarials and its applicability to plasmodial target identification.

Published in:

Wiener Klinische Wochenschrift, 2007, v. 119, p. 83, doi. 10.1007/s00508-007-0864-6

By:

Tasanor, Oumaporn;
Ernst, Marlies;
Thriemer, Kamala;
Ecker, Gerhard F.;
Noedl, Harald;
Chiba, Peter

Publication type:

Article

Intramolecular Distribution of Hydrophobicity Influences Pharmacological Activity of Propafenone-type MDR Modulators.

Published in:

Archiv der Pharmazie, 2004, v. 337, n. 6, p. 328, doi. 10.1002/ardp.200300862

By:

Karin Pleban;
Claudia Hoffer;
Stephan Kopp;
Michael Peer;
Peter Chiba;
Gerhard F. Ecker

Publication type:

Article

Lead Identification for Modulators of Multidrug Resistance based on in silico Screening with a Pharmacophoric Feature Model.

Published in:

Archiv der Pharmazie, 2004, v. 337, n. 6, p. 317, doi. 10.1002/ardp.200300817

By:

Thierry Langer;
Monika Eder;
Remy D. Hoffmann;
Peter Chiba

Publication type:

Article

Synthesis and Multidrug-Resistance Modulating Activity of a Series of Thienothiazines.

Published in:

Archiv der Pharmazie, 2002, v. 335, n. 5, p. 223, doi. 10.1002/1521-4184(200205)335:5<223::AID-ARDP223>3.0.CO;2-D

By:

Chiba, Peter;
Erker, Thomas;
Galanski, Maria;
Hitzler, Manuela;
Ecker, Gerhard F.

Publication type:

Article

A Combined Hansch/Free-Wilson Approach as Predictive Tool in QSAR Studies on Propafenone-Type Modulators of Multidrug Resistance.

Published in:

Archiv der Pharmazie, 1998, v. 331, n. 7/8, p. 233, doi. 10.1002/(SICI)1521-4184(199807)331:7/8<233::AID-ARDP233>3.0.CO;2-2

By:

Tmej, Claudia;
Chiba, Peter;
Huber, Mario;
Richter, Elisabeth;
Hitzler, Manuela;
Schaper, Klaus-Jürgen;
Ecker, Gerhard

Publication type:

Article

Studies on Propafenone-type Modulators of Multidrug-Resistance IV: Synthesis and Pharmacological Activity of 5-Hydroxy and 5-Benzyloxy Derivatives.

Published in:

Archiv der Pharmazie, 1997, v. 330, n. 11, p. 343, doi. 10.1002/ardp.19973301105

By:

Chiba, Peter;
Tell, Barbara;
Jäger, Walter;
Richter, Elisabeth;
Hitzlera, Manuela;
Ecker, Gerhard

Publication type:

Article

Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer.

Published in:

Drug Delivery, 2016, v. 23, n. 9, p. 3350, doi. 10.1080/10717544.2016.1178825

By:

Yuan, Yueling;
Cai, Tiange;
Xia, Xi;
Zhang, Ronghua;
Chiba, Peter;
Cai, Yu

Publication type:

Article

Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells.

Published in:

International Journal of Nanomedicine, 2019, v. 14, p. 2207, doi. 10.2147/IJN.S189924

By:

Yuan, Yueling;
Cai, Tiange;
Callaghan, Richard;
Li, Qianwen;
Huang, Yinghong;
Wang, Bingyue;
Huang, Qingqing;
Du, Manling;
Ma, Qianqian;
Chiba, Peter;
Cai, Yu

Publication type:

Article