Works matching AU Chial, Heidi J

Results: 29
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    Plasma biomarkers of neurodegeneration in the brain (UCH‐L1 and NfL) become exponentially higher with age from early childhood, and treatment of Alzheimer's disease participants with granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) lowers age‐associated levels of plasma UCH‐L1 by six decades

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.092726
    By:
    • Sillau, Stefan H;
    • Coughlan, Christina M;
    • Ahmed, Md. Mahiuddin;
    • Nair, Kavita V;
    • Araya, Paula;
    • Galbraith, Matthew D.;
    • Bettcher, Brianne M;
    • Espinosa, Joaquin M.;
    • Chial, Heidi J;
    • Epperson, Neill;
    • Boyd, Timothy D.;
    • Potter, Huntington
    Publication type:
    Article
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    The immune cytokine granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) is an effective treatment for both Alzheimer's disease and the viral diseases caused by West Nile Virus and SARS‐CoV‐2 infection, indicating that inflammation and viral infection may be partners and therapeutic co‐targets in many brain disorders

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080184
    By:
    • Potter, Huntington;
    • Boyd, Timothy D.;
    • Woodcock, Jonathan H;
    • Sillau, Stefan H;
    • Ahmed, Md. Mahiuddin;
    • Wang, Athena Ching‐Jung;
    • Chial, Heidi J;
    • Coughlan, Christina M;
    • Kendall, Lon V.;
    • Bosco‐Lauth, Angela;
    • Markham, Neil;
    • Stonedahl, Sarah;
    • Fong, Derek;
    • Clarke, Penny;
    • Tyler, Kenneth L.
    Publication type:
    Article
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    Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer’s disease.

    Published in:
    Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2021, v. 7, n. 1, p. 1, doi. 10.1002/trc2.12158
    By:
    • Potter, Huntington;
    • Woodcock, Jonathan H.;
    • Boyd, Timothy D.;
    • Coughlan, Christina M.;
    • O’Shaughnessy, John R.;
    • Borges, Manuel T.;
    • Thaker, Ashesh A.;
    • Raj, Balaibail A.;
    • Adamszuk, Katarzyna;
    • Scott, David;
    • Adame, Vanesa;
    • Anton, Paige;
    • Chial, Heidi J.;
    • Gray, Helen;
    • Daniels, Joseph;
    • Stocker, Michelle E.;
    • Sillau, Stefan H.
    Publication type:
    Article
    12

    Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer’s disease.

    Published in:
    Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2021, v. 7, n. 1, p. 1, doi. 10.1002/trc2.12158
    By:
    • Potter, Huntington;
    • Woodcock, Jonathan H.;
    • Boyd, Timothy D.;
    • Coughlan, ChristinaM.;
    • O’Shaughnessy, John R.;
    • Borges, Manuel T.;
    • Thaker, Ashesh A.;
    • Raj, Balaibail A.;
    • Adamszuk, Katarzyna;
    • Scott, David;
    • Adame, Vanesa;
    • Anton, Paige;
    • Chial, Heidi J.;
    • Gray, Helen;
    • Daniels, Joseph;
    • Stocker, Michelle E.;
    • Sillau, Stefan H.
    Publication type:
    Article
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    Increased Expression of Kif11/Kinesin‐5 mRNA Offsets Cognitive Deficits In An Alzheimer's Mouse Model, Blocks Aβ‐Mediated Decreases in Long‐Term Potentiation and Spine Density, and is Associated With Better Cognitive Performance in Alzheimer's Patients

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.068051
    By:
    • Lucero, Esteban M;
    • Freund, Ron;
    • Smith, Alexandra N.;
    • Johnson, Noah R;
    • Dooling, Breanna;
    • Sullivan, Emily;
    • Prikhodko, Olga;
    • Ahmed, Md. Mahiuddin;
    • Bennett, David A;
    • Hohman, Timothy J.;
    • DellAcqua, Mark;
    • Chial, Heidi J;
    • Potter, Huntington
    Publication type:
    Article
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    Granulocyte‐Macrophage Colony‐Stimulating Factor Reduces Two Major Pathological Hallmarks of Alzheimer's Disease and Astrogliosis in the TgF344‐AD Rat Model.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067785
    By:
    • Ahmed, Md. Mahiuddin;
    • Wang, Athena Ching‐Jung;
    • Boyd, Timothy D.;
    • Solano, D. Adriana;
    • Vielle, Anne;
    • Markham, Neil;
    • Coughlan, Christina M;
    • Chial, Heidi J;
    • Vergara, M. Natalia;
    • Potter, Huntington
    Publication type:
    Article
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    Identification of small molecule drugs that target apolipoprotein E4‐catalyzed amyloid‐β fibrillization: A new therapeutic approach to Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054678
    By:
    • Johnson, Noah R;
    • Wang, Athena Ching‐Jung;
    • Coughlan, Christina M;
    • Sillau, Stefan H;
    • Lucero, Esteban M;
    • Viltz, Lisa;
    • Markham, Neil;
    • Allen, Cody;
    • Dhanasekaran, A. Ranjitha;
    • Chial, Heidi J;
    • Potter, Huntington
    Publication type:
    Article
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    Small molecule inhibitors of apolipoprotein E4‐catalyzed amyloid‐β fibrillization as novel therapeutics for Alzheimer's disease: Development of new models and analysis methods/screening studies/platforms.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043353
    By:
    • Johnson, Noah R.;
    • Wang, Athena Ching‐Jung;
    • Coughlan, Christina M.;
    • Lucero, Esteban M.;
    • Viltz, Lisa;
    • Allen, Cody;
    • Markham, Neil;
    • Chial, Heidi J.;
    • Potter, Huntington
    Publication type:
    Article
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