Found: 11

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  • Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of <italic>C9ORF72</italic>-repeat induced toxicity.

    Published in:
    Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0545-x
    By:
    • Nicholson, Alexandra M.;
    • Zhou, Xiaolai;
    • Perkerson, Ralph B.;
    • Parsons, Tammee M.;
    • Chew, Jeannie;
    • Brooks, Mieu;
    • DeJesus-Hernandez, Mariely;
    • Finch, NiCole A.;
    • Matchett, Billie J.;
    • Kurti, Aishe;
    • Jansen-West, Karen R.;
    • Perkerson, Emilie;
    • Daughrity, Lillian;
    • Castanedes-Casey, Monica;
    • Rousseau, Linda;
    • Phillips, Virginia;
    • Hu, Fenghua;
    • Gendron, Tania F.;
    • Murray, Melissa E.;
    • Dickson, Dennis W.
    Publication type:
    Article

  • Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging.

    Published in:
    Nature Communications, 2016, v. 7, n. 10, p. 13283, doi. 10.1038/ncomms13283
    By:
    • Tian, Feng;
    • Yang, Wenlong;
    • Mordes, Daniel A.;
    • Wang, Jin-Yuan;
    • Salameh, Johnny S.;
    • Mok, Joanie;
    • Chew, Jeannie;
    • Sharma, Aarti;
    • Leno-Duran, Ester;
    • Suzuki-Uematsu, Satomi;
    • Suzuki, Naoki;
    • Han, Steve S.;
    • Lu, Fa-Ke;
    • Ji, Minbiao;
    • Zhang, Rosanna;
    • Liu, Yue;
    • Strominger, Jack;
    • Shneider, Neil A.;
    • Petrucelli, Leonard;
    • Xie, X. Sunney
    Publication type:
    Article

  • Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 383, p. 1, doi. 10.1126/scitranslmed.aai7866
    By:
    • Gendron, Tania F.;
    • Chew, Jeannie;
    • Stankowski, Jeannette N.;
    • Hayes, Lindsey R.;
    • Yong-Jie Zhang;
    • Prudencio, Mercedes;
    • Carlomagno, Yari;
    • Daughrity, Lillian M.;
    • Jansen-West, Karen;
    • Perkerson, Emilie A.;
    • O'Raw, Aliesha;
    • Cook, Casey;
    • Pregent, Luc;
    • Belzil, Veronique;
    • van Blitterswijk, Marka;
    • Tabassian, Lilia J.;
    • Lee, Chris W.;
    • Mei Yue;
    • Jimei Tong;
    • Yuping Song
    Publication type:
    Article

  • Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 6, p. 1467, doi. 10.1093/hmg/ddt534
    By:
    • Lee, Wing C.;
    • Almeida, Sandra;
    • Prudencio, Mercedes;
    • Caulfield, Thomas R.;
    • Zhang, Yong-Jie;
    • Tay, William M.;
    • Bauer, Peter O.;
    • Chew, Jeannie;
    • Sasaguri, Hiroki;
    • Jansen-West, Karen R.;
    • Gendron, Tania F.;
    • Stetler, Caroline T.;
    • Finch, NiCole;
    • Mackenzie, Ian R.;
    • Rademakers, Rosa;
    • Gao, Fen-Biao;
    • Petrucelli, Leonard
    Publication type:
    Article

  • Correction to: ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.

    Published in:
    2019
    By:
    • Moore, Stephen;
    • Alsop, Eric;
    • Lorenzini, Ileana;
    • Starr, Alexander;
    • Rabichow, Benjamin E.;
    • Mendez, Emily;
    • Levy, Jennifer L.;
    • Burciu, Camelia;
    • Reiman, Rebecca;
    • Chew, Jeannie;
    • Belzil, Veronique V.;
    • Dickson, Dennis;
    • Robertson, Janice;
    • Staats, Kim A.;
    • Ichida, Justin K.;
    • Petrucelli, Leonard;
    • Van Keuren-Jensen, Kendall;
    • Sattler, Rita
    Publication type:
    Correction Notice

  • ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 1, p. 49, doi. 10.1007/s00401-019-01999-w
    By:
    • Lorenzini, Ileana;
    • Starr, Alexander;
    • Rabichow, Benjamin E.;
    • Mendez, Emily;
    • Levy, Jennifer L.;
    • Burciu, Camelia;
    • Sattler, Rita;
    • Moore, Stephen;
    • Alsop, Eric;
    • Reiman, Rebecca;
    • Van Keuren-Jensen, Kendall;
    • Chew, Jeannie;
    • Belzil, Veronique V.;
    • W. Dickson, Dennis;
    • Petrucelli, Leonard;
    • Robertson, Janice;
    • Staats, Kim A.;
    • Ichida, Justin K.
    Publication type:
    Article

  • In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers.

    Published in:
    Acta Neuropathologica, 2017, v. 134, n. 2, p. 255, doi. 10.1007/s00401-017-1725-7
    By:
    • DeJesus-Hernandez, Mariely;
    • Finch, NiCole;
    • Wang, Xue;
    • Gendron, Tania;
    • Bieniek, Kevin;
    • Heckman, Michael;
    • Vasilevich, Aliaksei;
    • Murray, Melissa;
    • Rousseau, Linda;
    • Weesner, Rachael;
    • Lucido, Anthony;
    • Parsons, Meeia;
    • Chew, Jeannie;
    • Josephs, Keith;
    • Parisi, Joseph;
    • Knopman, David;
    • Petersen, Ronald;
    • Boeve, Bradley;
    • Graff-Radford, Neill;
    • de Boer, Jan
    Publication type:
    Article

  • Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.

    Published in:
    Acta Neuropathologica, 2014, v. 128, n. 4, p. 505, doi. 10.1007/s00401-014-1336-5
    By:
    • Zhang, Yong-Jie;
    • Jansen-West, Karen;
    • Xu, Ya-Fei;
    • Gendron, Tania;
    • Bieniek, Kevin;
    • Lin, Wen-Lang;
    • Sasaguri, Hiroki;
    • Caulfield, Thomas;
    • Hubbard, Jaime;
    • Daughrity, Lillian;
    • Chew, Jeannie;
    • Belzil, Veronique;
    • Prudencio, Mercedes;
    • Stankowski, Jeannette;
    • Castanedes-Casey, Monica;
    • Whitelaw, Ena;
    • Ash, Peter;
    • DeTure, Michael;
    • Rademakers, Rosa;
    • Boylan, Kevin
    Publication type:
    Article

  • Antisense transcripts of the expanded <i>C9ORF72</i> hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.

    Published in:
    Acta Neuropathologica, 2013, v. 126, n. 6, p. 829, doi. 10.1007/s00401-013-1192-8
    By:
    • Gendron, Tania F.;
    • Bieniek, Kevin F.;
    • Zhang, Yong-Jie;
    • Jansen-West, Karen;
    • Ash, Peter E. A.;
    • Caulfield, Thomas;
    • Daughrity, Lillian;
    • Dunmore, Judith H.;
    • Castanedes-Casey, Monica;
    • Chew, Jeannie;
    • Cosio, Danielle M.;
    • van Blitterswijk, Marka;
    • Lee, Wing C.;
    • Rademakers, Rosa;
    • Boylan, Kevin B.;
    • Dickson, Dennis W.;
    • Petrucelli, Leonard
    Publication type:
    Article

  • The lysosomal protein cathepsin L is a progranulin protease.

    Published in:
    Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0196-6
    By:
    • Lee, Chris W.;
    • Stankowski, Jeannette N.;
    • Jeannie Chew;
    • Cook, Casey N.;
    • Ying-Wai Lam;
    • Almeida, Sandra;
    • Carlomagno, Yari;
    • Kwok-Fai Lau;
    • Prudencio, Mercedes;
    • Fen-Biao Gao;
    • Bogyo, Matthew;
    • Dickson, Dennis W.;
    • Petrucelli, Leonard
    Publication type:
    Article

  • Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.

    Published in:
    Molecular Neurodegeneration, 2019, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13024-019-0310-z
    By:
    • Chew, Jeannie;
    • Cook, Casey;
    • Gendron, Tania F.;
    • Jansen-West, Karen;
    • del Rosso, Giulia;
    • Daughrity, Lillian M.;
    • Castanedes-Casey, Monica;
    • Kurti, Aishe;
    • Stankowski, Jeannette N.;
    • Disney, Matthew D.;
    • Rothstein, Jeffrey D.;
    • Dickson, Dennis W.;
    • Fryer, John D.;
    • Zhang, Yong-Jie;
    • Petrucelli, Leonard
    Publication type:
    Article