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Enhanced Na<sup>+</sup> -K<sup>+</sup> -2Cl<sup>-</sup> cotransporter 1 underlies motor dysfunction in huntington's disease.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Altered behavioral responses to gamma-aminobutyric acid pharmacological agents in a mouse model of Huntington's disease.
- Published in:
- 2017
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- Publication type:
- journal article
Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D<sub>2</sub> and adenosine A<sub>2A</sub> receptors.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0529-z
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- Publication type:
- Article
Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect.
- Published in:
- Scientific Reports, 2015, p. 1, doi. 10.1038/srep14992
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- Publication type:
- Article
Exploring the role of hub and network dysfunction in brain connectomes of schizophrenia using functional magnetic resonance imaging.
- Published in:
- Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2023.1305359
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- Publication type:
- Article
The D2 Dopamine Receptor Interferes With the Protective Effect of the A<sub>2A</sub> Adenosine Receptor on TDP-43 Mislocalization in Experimental Models of Motor Neuron Degeneration.
- Published in:
- Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00187
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- Publication type:
- Article
Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis.
- Published in:
- FEBS Letters, 2015, v. 589, n. 4, p. 432, doi. 10.1016/j.febslet.2014.12.029
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- Publication type:
- Article
Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.
- Published in:
- Cellular & Molecular Life Sciences, 2012, v. 69, n. 24, p. 4107, doi. 10.1007/s00018-012-1025-2
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- Publication type:
- Article
Expanded-Polyglutamine Huntingtin Protein Suppresses the Secretion and Production of a Chemokine (CCL5/RANTES) by Astrocytes.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 13, p. 3277, doi. 10.1523/JNEUROSCI.0116-08.2008
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- Publication type:
- Article
Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms.
- Published in:
- Journal of Neurochemistry, 2011, v. 116, n. 6, p. 1112, doi. 10.1111/j.1471-4159.2010.07166.x
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- Publication type:
- Article
CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.
- Published in:
- Journal of Neurochemistry, 2005, v. 93, n. 2, p. 310, doi. 10.1111/j.1471-4159.2005.03029.x
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- Publication type:
- Article
Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington's disease.
- Published in:
- Journal of Cell Biology, 2011, v. 194, n. 2, p. 209, doi. 10.1083/jcb.201105010
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- Publication type:
- Article
Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 6, p. 1602, doi. 10.1093/hmg/ddu574
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- Publication type:
- Article
Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 3, p. 787, doi. 10.1093/hmg/ddu497
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- Publication type:
- Article
Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 16, p. 4328, doi. 10.1093/hmg/ddu151
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- Publication type:
- Article
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2013, v. 22, n. 9, p. 1826, doi. 10.1093/hmg/ddt036
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- Publication type:
- Article
Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 20, p. 4043, doi. 10.1093/hmg/ddq322
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- Publication type:
- Article
The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin–proteasome system.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 16, p. 2929, doi. 10.1093/hmg/ddp230
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- Publication type:
- Article
Dysregulation of C/EBPα by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 5, p. 483, doi. 10.1093/hmg/ddl481
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- Publication type:
- Article
Emerging roles of dysregulated adenosine homeostasis in brain disorders with a specific focus on neurodegenerative diseases.
- Published in:
- Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00766-y
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- Publication type:
- Article
Contribution of Energy Dysfunction to Impaired Protein Translation in Neurodegenerative Diseases.
- Published in:
- Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.668500
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- Publication type:
- Article
Beneficial Effect of a Selective Adenosine A<sub>2A</sub> Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnmol.2018.00235
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- Publication type:
- Article
Microglial Lectins in Health and Neurological Diseases.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00158
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- Publication type:
- Article
Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Aberrant astrocytes impair vascular reactivity in Huntington disease.
- Published in:
- Annals of Neurology, 2015, v. 78, n. 2, p. 178, doi. 10.1002/ana.24428
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- Publication type:
- Article
The Impact of Dysregulated microRNA Biogenesis Machinery and microRNA Sorting on Neurodegenerative Diseases.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3443, doi. 10.3390/ijms24043443
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- Publication type:
- Article
Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord Injury.
- Published in:
- Molecular Neurobiology, 2023, v. 60, n. 1, p. 369, doi. 10.1007/s12035-022-03080-2
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- Publication type:
- Article
Twist1 Plays an Anti-apoptotic Role in Mutant Huntingtin Expression Striatal Progenitor Cells.
- Published in:
- Molecular Neurobiology, 2020, v. 57, n. 3, p. 1688, doi. 10.1007/s12035-019-01836-x
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- Publication type:
- Article
Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 12, p. 8936, doi. 10.1007/s12035-018-1030-z
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- Publication type:
- Article
Targeting Glial Cells to Elucidate the Pathogenesis of Huntington’s Disease.
- Published in:
- Molecular Neurobiology, 2010, v. 41, n. 2/3, p. 248, doi. 10.1007/s12035-009-8097-5
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- Publication type:
- Article
Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01213-7
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- Publication type:
- Article
The A<sub>2A</sub> adenosine receptor rescues neuritogenesis impaired by p53 blockage via KIF2A, a kinesin family member.
- Published in:
- Developmental Neurobiology (19328451), 2010, v. 70, n. 8, p. 604, doi. 10.1002/dneu.20802
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- Publication type:
- Article
Hydrogen peroxide induces loss of dopamine transporter activity: a calcium-dependent oxidative mechanism.
- Published in:
- Journal of Neurochemistry, 2003, v. 86, n. 5, p. 1247, doi. 10.1046/j.1471-4159.2003.01936.x
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- Publication type:
- Article
The 5' Untranslated Regions of the Rat A<sub>2A</sub> Adenosine Receptor Gene Function as Negative Translational Regulators.
- Published in:
- Journal of Neurochemistry, 1999, v. 73, n. 5, p. 1790, doi. 10.1046/j.1471-4159.1999.0731790.x
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- Publication type:
- Article
Modulation of Dopamine Transporter Activity by Nicotinic AcetylcholineReceptors and Membrane Depolarization in Rat Pheochromocytoma PC12 Cells.
- Published in:
- Journal of Neurochemistry, 1999, v. 72, n. 6, p. 2437, doi. 10.1046/j.1471-4159.1999.0722437.x
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- Publication type:
- Article
Activation of Phosphodiesterase IV During Desensitization of the A<sub>2A</sub> Adenosine Receptor-Mediated Cyclic AMP Response in Rat Pheochromocytoma (PC12) Cells.
- Published in:
- Journal of Neurochemistry, 1997, v. 69, n. 3, p. 1300, doi. 10.1046/j.1471-4159.1997.69031300.x
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- Publication type:
- Article
Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pgen.1005043
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- Publication type:
- Article
Anticonvulsant effect of equilibrative nucleoside transporters 1 inhibitor in a mouse model of Dravet syndrome.
- Published in:
- Hippocampus, 2024, v. 34, n. 1, p. 7, doi. 10.1002/hipo.23584
- By:
- Publication type:
- Article
Degeneration of ipRGCs in Mouse Models of Huntington's Disease Disrupts Non-Image-Forming Behaviors Before Motor Impairment.
- Published in:
- Journal of Neuroscience, 2019, v. 39, n. 8, p. 1505, doi. 10.1523/JNEUROSCI.0571-18.2018
- By:
- Publication type:
- Article
The Influence of Pathological Mutations and Proline Substitutions in TDP-43 Glycine-Rich Peptides on Its Amyloid Properties and Cellular Toxicity.
- Published in:
- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103644
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- Publication type:
- Article
Adenosine A<sub>2A</sub> Receptor Up-Regulates Retinal Wave Frequency via Starburst Amacrine Cells in the Developing Rat Retina.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095090
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- Publication type:
- Article
Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022924
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- Publication type:
- Article
A New Drug Design Targeting the Adenosinergic System for Huntington's Disease.
- Published in:
- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020934
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- Publication type:
- Article
Regulation of P-glycoprotein expression in brain capillaries in Huntington's disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 8, p. 1412, doi. 10.1177/0271678X15606459
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- Publication type:
- Article
Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning.
- Published in:
- Scientific Reports, 2016, p. 22529, doi. 10.1038/srep22529
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- Publication type:
- Article
Neurovascular abnormalities in brain disorders: highlights with angiogenesis and magnetic resonance imaging studies.
- Published in:
- Journal of Biomedical Science, 2013, v. 20, n. 1, p. 1, doi. 10.1186/1423-0127-20-47
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- Publication type:
- Article
Design and Synthesis of Novel Dual-Action Compounds Targeting the Adenosine A<sub>2A</sub> Receptor and Adenosine Transporter for Neuroprotection.
- Published in:
- ChemMedChem, 2011, v. 6, n. 8, p. 1390, doi. 10.1002/cmdc.201100126
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- Publication type:
- Article
Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration.
- Published in:
- Journal of Neuroscience, 2022, v. 42, n. 25, p. 5102, doi. 10.1523/JNEUROSCI.2006-21.2022
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- Publication type:
- Article
Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease.
- Published in:
- Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1519, doi. 10.1172/JCI43220
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- Publication type:
- Article
The TRAX, DISC1, and GSK3 complex in mental disorders and therapeutic interventions.
- Published in:
- Journal of Biomedical Science, 2018, v. 25, n. 1, p. N.PAG, doi. 10.1186/s12929-018-0473-x
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- Publication type:
- Article