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The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.
Published in:
Nature Reviews Drug Discovery, 2013, v. 12, n. 1, p. 25, doi. 10.1038/nrd3859
By:
- Stevens, Raymond C.;
- Cherezov, Vadim;
- Katritch, Vsevolod;
- Abagyan, Ruben;
- Kuhn, Peter;
- Rosen, Hugh;
- Wüthrich, Kurt
Publication type:
Article
Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.
Published in:
2020
By:
- Marin, Egor;
- Luginina, Aleksandra;
- Gusach, Anastasiia;
- Kovalev, Kirill;
- Bukhdruker, Sergey;
- Khorn, Polina;
- Polovinkin, Vitaly;
- Lyapina, Elizaveta;
- Rogachev, Andrey;
- Gordeliy, Valentin;
- Mishin, Alexey;
- Cherezov, Vadim;
- Borshchevskiy, Valentin
Publication type:
Correction Notice
Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.
Published in:
Scientific Data, 2020, v. 7, n. 1, p. N.PAG, doi. 10.1038/s41597-020-00729-2
By:
- Marin, Egor;
- Luginina, Aleksandra;
- Gusach, Anastasiia;
- Kovalev, Kirill;
- Bukhdruker, Sergey;
- Khorn, Polina;
- Polovinkin, Vitaly;
- Lyapina, Elizaveta;
- Rogachev, Andrey;
- Gordeliy, Valentin;
- Mishin, Alexey;
- Cherezov, Vadim;
- Borshchevskiy, Valentin
Publication type:
Article
Structural insights on ligand recognition at the human leukotriene B4 receptor 1.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23149-1
By:
- Michaelian, Nairie;
- Sadybekov, Anastasiia;
- Besserer-Offroy, Élie;
- Han, Gye Won;
- Krishnamurthy, Harini;
- Zamlynny, Beata A.;
- Fradera, Xavier;
- Siliphaivanh, Phieng;
- Presland, Jeremy;
- Spencer, Kerrie B.;
- Soisson, Stephen M.;
- Popov, Petr;
- Sarret, Philippe;
- Katritch, Vsevolod;
- Cherezov, Vadim
Publication type:
Article
Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists.
Published in:
EMBO Journal, 2023, v. 42, n. 11, p. 1, doi. 10.15252/embj.2022112940
By:
- Zhang, Dongqi;
- Liu, Yongfeng;
- Zaidi, Saheem A;
- Xu, Lingyi;
- Zhan, Yuting;
- Chen, Anqi;
- Guo, Jiangtao;
- Huang, Xi‐Ping;
- Roth, Bryan L;
- Katritch, Vsevolod;
- Cherezov, Vadim;
- Zhang, Haitao
Publication type:
Article
High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022348
By:
- Tiefenbrunn, Theresa;
- Wei Liu;
- Ying Chen;
- Katritch, Vsevolod;
- Stout, C. David;
- Fee, James A.;
- Cherezov, Vadim
Publication type:
Article
In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.
Published in:
Proteins, 2008, v. 71, n. 1, p. 24, doi. 10.1002/prot.21841
By:
- Cherezov, Vadim;
- Liu, Wei;
- Derrick, Jeremy P.;
- Luan, Binquan;
- Aksimentiev, Aleksei;
- Katritch, Vsevolod;
- Caffrey, Martin
Publication type:
Article
Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR.
Published in:
Biomolecules (2218-273X), 2020, v. 10, n. 12, p. 1634, doi. 10.3390/biom10121634
By:
- Sadybekov, Arman A.;
- Brouillette, Rebecca L.;
- Marin, Egor;
- Sadybekov, Anastasiia V.;
- Luginina, Aleksandra;
- Gusach, Anastasiia;
- Mishin, Alexey;
- Besserer-Offroy, Élie;
- Longpré, Jean-Michel;
- Borshchevskiy, Valentin;
- Cherezov, Vadim;
- Sarret, Philippe;
- Katritch, Vsevolod
Publication type:
Article
Structural insights into melatonin receptors.
Published in:
FEBS Journal, 2020, v. 287, n. 8, p. 1496, doi. 10.1111/febs.15128
By:
- Stauch, Benjamin;
- Johansson, Linda C.;
- Cherezov, Vadim
Publication type:
Article
Structure of the human histamine H1 receptor complex with doxepin.
Published in:
Nature, 2011, v. 475, n. 7354, p. 65, doi. 10.1038/nature10236
By:
- Shimamura, Tatsuro;
- Shiroishi, Mitsunori;
- Weyand, Simone;
- Tsujimoto, Hirokazu;
- Winter, Graeme;
- Katritch, Vsevolod;
- Abagyan, Ruben;
- Cherezov, Vadim;
- Wei Liu;
- Han, Gye Won;
- Kobayashi, Takuya;
- Stevens, Raymond C.;
- Iwata, So
Publication type:
Article
Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.74989
By:
- Barekatain, Mahta;
- Yameng Liu;
- Archambeau, Ashley;
- Cherezov, Vadim;
- Fraser, Scott;
- White, Kate L.;
- Hayes, Mark A.
Publication type:
Article
On the Origin of the Anomalous Behavior of Lipid Membrane Properties in the Vicinity of the Chain-Melting Phase Transition.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62577-9
By:
- Kuklin, Alexander;
- Zabelskii, Dmitrii;
- Gordeliy, Ivan;
- Teixeira, José;
- Brûlet, Annie;
- Chupin, Vladimir;
- Cherezov, Vadim;
- Gordeliy, Valentin
Publication type:
Article
Structural dynamics of the A2A adenosine receptor revealed by single‐molecule FRET.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04977
By:
- Maslov, Ivan;
- Volkov, Oleksandr;
- Khorn, Polina;
- Orekhov, Philipp;
- Gusach, Anastasiia;
- Kuzmichev, Pavel;
- Gerasimov, Andrey;
- Luginina, Aleksandra;
- Coucke, Quinten;
- Bogorodskiy, Andrey;
- Gordeliy, Valentin;
- Wanninger, Simon;
- Barth, Anders;
- Mishin, Alexey;
- Hofkens, Johan;
- Cherezov, Vadim;
- Gensch, Thomas;
- Hendrix, Jelle;
- Borshchevskiy, Valentin
Publication type:
Article
Interaction of Polyunsaturated Fatty Acids with Cholesterol: A Role in Lipid Raft Phase Separation.
Published in:
Macromolecular Symposia, 2005, v. 219, n. 1, p. 73, doi. 10.1002/masy.200550108
By:
- Wassall, Stephen R.;
- Shaikh, Saame Raza;
- Brzustowicz, Michael R.;
- Cherezov, Vadim;
- Siddiqui, Rafat A.;
- Caffrey, Martin;
- Stillwell, William
Publication type:
Article
Analysis of full and partial agonists binding to β.
Published in:
Journal of Molecular Recognition, 2009, v. 22, n. 4, p. 307, doi. 10.1002/jmr.949
By:
- Katritch, Vsevolod;
- Reynolds, Kimberly A.;
- Cherezov, Vadim;
- Hanson, Michael A.;
- Roth, Christopher B.;
- Yeager, Mark;
- Abagyan, Ruben
Publication type:
Article
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Published in:
Nature Communications, 2017, v. 8, n. 5, p. 15383, doi. 10.1038/ncomms15383
By:
- Zhang, Xianjun;
- Zhao, Fei;
- Wu, Yiran;
- Yang, Jun;
- Han, Gye Won;
- Zhao, Suwen;
- Ishchenko, Andrii;
- Ye, Lintao;
- Lin, Xi;
- Ding, Kang;
- Dharmarajan, Venkatasubramanian;
- Griffin, Patrick R.;
- Gati, Cornelius;
- Nelson, Garrett;
- Hunter, Mark S.;
- Hanson, Michael A.;
- Cherezov, Vadim;
- Stevens, Raymond C.;
- Tan, Wenfu;
- Tao, Houchao
Publication type:
Article
Ternary structure reveals mechanism of a membrane diacylglycerol kinase.
Published in:
Nature Communications, 2015, v. 6, n. 12, p. 10140, doi. 10.1038/ncomms10140
By:
- Li, Dianfan;
- Stansfeld, Phillip J.;
- Sansom, Mark S. P.;
- Keogh, Aaron;
- Vogeley, Lutz;
- Howe, Nicole;
- Lyons, Joseph A.;
- Aragao, David;
- Fromme, Petra;
- Fromme, Raimund;
- Basu, Shibom;
- Grotjohann, Ingo;
- Kupitz, Christopher;
- Rendek, Kimberley;
- Weierstall, Uwe;
- Zatsepin, Nadia A.;
- Cherezov, Vadim;
- Liu, Wei;
- Bandaru, Sateesh;
- English, Niall J.
Publication type:
Article
Constitutive phospholipid scramblase activity of a G protein-coupled receptor.
Published in:
Nature Communications, 2014, v. 5, n. 10, p. 5115, doi. 10.1038/ncomms6115
By:
- Goren, Michael A.;
- Morizumi, Takefumi;
- Menon, Indu;
- Joseph, Jeremiah S.;
- Dittman, Jeremy S.;
- Cherezov, Vadim;
- Stevens, Raymond C.;
- Ernst, Oliver P.;
- Menon, Anant K.
Publication type:
Article
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.
Published in:
Nature Communications, 2014, v. 5, n. 7, p. 4355, doi. 10.1038/ncomms5355
By:
- Wang, Chong;
- Wu, Huixian;
- Evron, Tama;
- Vardy, Eyal;
- Han, Gye Won;
- Huang, Xi-Ping;
- Hufeisen, Sandy J.;
- Mangano, Thomas J.;
- Urban, Dan J.;
- Katritch, Vsevolod;
- Cherezov, Vadim;
- Caron, Marc G.;
- Roth, Bryan L.;
- Stevens, Raymond C.
Publication type:
Article
GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.
Published in:
Naunyn-Schmiedeberg's Archives of Pharmacology, 2015, v. 388, n. 8, p. 883, doi. 10.1007/s00210-015-1111-8
By:
- Heifetz, Alexander;
- Schertler, Gebhard;
- Seifert, Roland;
- Tate, Christopher;
- Sexton, Patrick;
- Gurevich, Vsevolod;
- Fourmy, Daniel;
- Cherezov, Vadim;
- Marshall, Fiona;
- Storer, R.;
- Moraes, Isabel;
- Tikhonova, Irina;
- Tautermann, Christofer;
- Hunt, Peter;
- Ceska, Tom;
- Hodgson, Simon;
- Bodkin, Mike;
- Singh, Shweta;
- Law, Richard;
- Biggin, Philip
Publication type:
Article
Picolitre-scale crystallization of membrane proteins.
Published in:
Journal of Applied Crystallography, 2006, v. 39, n. 4, p. 604, doi. 10.1107/S0021889806022953
By:
- Cherezov, Vadim;
- Caffrey, Martin
Publication type:
Article
A simple and inexpensive nanoliter-volume dispenser for highly viscous materials used in membrane protein crystallization.
Published in:
Journal of Applied Crystallography, 2005, v. 38, n. 2, p. 398, doi. 10.1107/S0021889805001640
By:
- Cherezov, Vadim;
- Caffrey, Martin
Publication type:
Article
Nano-volume plates with excellent optical properties for fast, inexpensive crystallization screening of membrane proteins.
Published in:
Journal of Applied Crystallography, 2003, v. 36, n. 6, p. 1372, doi. 10.1107/S002188980301906X
By:
- Cherezov, Vadim;
- Caffrey, Martin
Publication type:
Article
Two disparate ligand-binding sites in the human P2Y1 receptor.
Published in:
Nature, 2015, v. 520, n. 7547, p. 317, doi. 10.1038/nature14287
By:
- Zhang, Dandan;
- Gao, Zhan-Guo;
- Zhang, Kaihua;
- Kiselev, Evgeny;
- Crane, Steven;
- Wang, Jiang;
- Paoletta, Silvia;
- Yi, Cuiying;
- Ma, Limin;
- Zhang, Wenru;
- Han, Gye Won;
- Liu, Hong;
- Cherezov, Vadim;
- Katritch, Vsevolod;
- Jiang, Hualiang;
- Stevens, Raymond C.;
- Jacobson, Kenneth A.;
- Zhao, Qiang;
- Wu, Beili
Publication type:
Article
Structure of the human P2Y12 receptor in complex with an antithrombotic drug.
Published in:
Nature, 2014, v. 509, n. 7498, p. 115, doi. 10.1038/nature13083
By:
- Zhang, Kaihua;
- Zhang, Jin;
- Gao, Zhan-Guo;
- Zhang, Dandan;
- Zhu, Lan;
- Han, Gye Won;
- Moss, Steven M.;
- Paoletta, Silvia;
- Kiselev, Evgeny;
- Lu, Weizhen;
- Fenalti, Gustavo;
- Zhang, Wenru;
- Müller, Christa E.;
- Yang, Huaiyu;
- Jiang, Hualiang;
- Cherezov, Vadim;
- Katritch, Vsevolod;
- Jacobson, Kenneth A.;
- Stevens, Raymond C.;
- Wu, Beili
Publication type:
Article
Agonist-bound structure of the human P2Y12 receptor.
Published in:
Nature, 2014, v. 509, n. 7498, p. 119, doi. 10.1038/nature13288
By:
- Zhang, Jin;
- Zhang, Kaihua;
- Gao, Zhan-Guo;
- Paoletta, Silvia;
- Zhang, Dandan;
- Han, Gye Won;
- Li, Tingting;
- Ma, Limin;
- Zhang, Wenru;
- Müller, Christa E.;
- Yang, Huaiyu;
- Jiang, Hualiang;
- Cherezov, Vadim;
- Katritch, Vsevolod;
- Jacobson, Kenneth A.;
- Stevens, Raymond C.;
- Wu, Beili;
- Zhao, Qiang
Publication type:
Article
Molecular control of δ-opioid receptor signalling.
Published in:
Nature, 2014, v. 506, n. 7487, p. 191, doi. 10.1038/nature12944
By:
- Fenalti, Gustavo;
- Giguere, Patrick M.;
- Katritch, Vsevolod;
- Huang, Xi-Ping;
- Thompson, Aaron A.;
- Cherezov, Vadim;
- Roth, Bryan L.;
- Stevens, Raymond C.
Publication type:
Article
Structure of the human glucagon class B G-protein-coupled receptor.
Published in:
Nature, 2013, v. 499, n. 7459, p. 444, doi. 10.1038/nature12393
By:
- Siu, Fai Yiu;
- He, Min;
- de Graaf, Chris;
- Han, Gye Won;
- Yang, Dehua;
- Zhang, Zhiyun;
- Zhou, Caihong;
- Xu, Qingping;
- Wacker, Daniel;
- Joseph, Jeremiah S.;
- Liu, Wei;
- Lau, Jesper;
- Cherezov, Vadim;
- Katritch, Vsevolod;
- Wang, Ming-Wei;
- Stevens, Raymond C.
Publication type:
Article
Structure of the human smoothened receptor bound to an antitumour agent.
Published in:
Nature, 2013, v. 497, n. 7449, p. 338, doi. 10.1038/nature12167
By:
- Wang, Chong;
- Wu, Huixian;
- Katritch, Vsevolod;
- Han, Gye Won;
- Huang, Xi-Ping;
- Liu, Wei;
- Siu, Fai Yiu;
- Roth, Bryan L.;
- Cherezov, Vadim;
- Stevens, Raymond C.
Publication type:
Article
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.
Published in:
Nature, 2012, v. 485, n. 7398, p. 395, doi. 10.1038/nature11085
By:
- Thompson, Aaron A.;
- Liu, Wei;
- Chun, Eugene;
- Katritch, Vsevolod;
- Wu, Huixian;
- Vardy, Eyal;
- Huang, Xi-Ping;
- Trapella, Claudio;
- Guerrini, Remo;
- Calo, Girolamo;
- Roth, Bryan L.;
- Cherezov, Vadim;
- Stevens, Raymond C.
Publication type:
Article
Structure of the human ?-opioid receptor in complex with JDTic.
Published in:
Nature, 2012, v. 485, n. 7398, p. 327, doi. 10.1038/nature10939
By:
- Wu, Huixian;
- Wacker, Daniel;
- Mileni, Mauro;
- Katritch, Vsevolod;
- Han, Gye Won;
- Vardy, Eyal;
- Liu, Wei;
- Thompson, Aaron A.;
- Huang, Xi-Ping;
- Carroll, F. Ivy;
- Mascarella, S. Wayne;
- Westkaemper, Richard B.;
- Mosier, Philip D.;
- Roth, Bryan L.;
- Cherezov, Vadim;
- Stevens, Raymond C.
Publication type:
Article
Cover Feature: Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity (Chem. Eur. J. 47/2020).
Published in:
Chemistry - A European Journal, 2020, v. 26, n. 47, p. 10646, doi. 10.1002/chem.202003569
By:
- Vrettos, Eirinaios I.;
- Valverde, Ibai E.;
- Mascarin, Alba;
- Pallier, Patrick N.;
- Cerofolini, Linda;
- Fragai, Marco;
- Parigi, Giacomo;
- Hirmiz, Baydaa;
- Bekas, Nick;
- Grob, Nathalie M.;
- Stylos, Evgenios Κ.;
- Shaye, Hamidreza;
- Del Borgo, Mark;
- Aguilar, Marie‐Isabel;
- Magnani, Francesca;
- Syed, Nelofer;
- Crook, Timothy;
- Waqif, Emal;
- Ghazaly, Essam;
- Cherezov, Vadim
Publication type:
Article
Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.
Published in:
Chemistry - A European Journal, 2020, v. 26, n. 47, p. 10690, doi. 10.1002/chem.202000924
By:
- Vrettos, Eirinaios I.;
- Valverde, Ibai E.;
- Mascarin, Alba;
- Pallier, Patrick N.;
- Cerofolini, Linda;
- Fragai, Marco;
- Parigi, Giacomo;
- Hirmiz, Baydaa;
- Bekas, Nick;
- Grob, Nathalie M.;
- Stylos, Evgenios Κ.;
- Shaye, Hamidreza;
- Del Borgo, Mark;
- Aguilar, Marie‐Isabel;
- Magnani, Francesca;
- Syed, Nelofer;
- Crook, Timothy;
- Waqif, Emal;
- Ghazaly, Essam;
- Cherezov, Vadim
Publication type:
Article
High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.
Published in:
Nature Protocols, 2018, v. 13, n. 2, p. 260, doi. 10.1038/nprot.2017.135
By:
- Broecker, Jana;
- Morizumi, Takefumi;
- Ou, Wei-Lin;
- Klingel, Viviane;
- Kuo, Anling;
- Kissick, David J;
- Ishchenko, Andrii;
- Lee, Ming-Yue;
- Xu, Shenglan;
- Makarov, Oleg;
- Cherezov, Vadim;
- Ogata, Craig M;
- Ernst, Oliver P
Publication type:
Article
Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.
Published in:
Nature Protocols, 2014, v. 9, n. 9, p. 2123, doi. 10.1038/nprot.2014.141
By:
- Liu, Wei;
- Ishchenko, Andrii;
- Cherezov, Vadim
Publication type:
Article
Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline.
Published in:
Journal of Synchrotron Radiation, 2013, v. 20, n. 4, p. 531, doi. 10.1107/S0909049513007942
By:
- Madden, Jeremy T.;
- Toth, Scott J.;
- Dettmar, Christopher M.;
- Newman, Justin A.;
- Oglesbee, Robert A.;
- Hedderich, Hartmut G.;
- Everly, R. Michael;
- Becker, Michael;
- Ronau, Judith A.;
- Buchanan, Susan K.;
- Cherezov, Vadim;
- Morrow, Marie E.;
- Xu, Shenglan;
- Ferguson, Dale;
- Makarov, Oleg;
- Das, Chittaranjan;
- Fischetti, Robert;
- Simpson, Garth J.
Publication type:
Article
Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases.
Published in:
Journal of Synchrotron Radiation, 2002, v. 9, n. 6, p. 333, doi. 10.1107/S0909049502014528
By:
- Cherezov, Vadim;
- Riedl, Ken M.;
- Caffrey, Martin
Publication type:
Article
Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04727-z
By:
- Maslov, Ivan;
- Volkov, Oleksandr;
- Khorn, Polina;
- Orekhov, Philipp;
- Gusach, Anastasiia;
- Kuzmichev, Pavel;
- Gerasimov, Andrey;
- Luginina, Aleksandra;
- Coucke, Quinten;
- Bogorodskiy, Andrey;
- Gordeliy, Valentin;
- Wanninger, Simon;
- Barth, Anders;
- Mishin, Alexey;
- Hofkens, Johan;
- Cherezov, Vadim;
- Gensch, Thomas;
- Hendrix, Jelle;
- Borshchevskiy, Valentin
Publication type:
Article
The activation mechanism and antibody binding mode for orphan GPR20.
Published in:
Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00520-8
By:
- Lin, Xi;
- Jiang, Shan;
- Wu, Yiran;
- Wei, Xiaohu;
- Han, Gye-Won;
- Wu, Lijie;
- Liu, Junlin;
- Chen, Bo;
- Zhang, Zhibin;
- Zhao, Suwen;
- Cherezov, Vadim;
- Xu, Fei
Publication type:
Article

Found: 39

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.

Structural insights on ligand recognition at the human leukotriene B4 receptor 1.

Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists.

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment.

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR.

Structural insights into melatonin receptors.

Structure of the human histamine H<sub>1</sub> receptor complex with doxepin.

Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles.

On the Origin of the Anomalous Behavior of Lipid Membrane Properties in the Vicinity of the Chain-Melting Phase Transition.

Structural dynamics of the A<sub>2A</sub> adenosine receptor revealed by single‐molecule FRET.

Interaction of Polyunsaturated Fatty Acids with Cholesterol: A Role in Lipid Raft Phase Separation.

Analysis of full and partial agonists binding to β.

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.

Ternary structure reveals mechanism of a membrane diacylglycerol kinase.

Constitutive phospholipid scramblase activity of a G protein-coupled receptor.

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Picolitre-scale crystallization of membrane proteins.

A simple and inexpensive nanoliter-volume dispenser for highly viscous materials used in membrane protein crystallization.

Nano-volume plates with excellent optical properties for fast, inexpensive crystallization screening of membrane proteins.

Two disparate ligand-binding sites in the human P2Y<sub>1</sub> receptor.

Structure of the human P2Y<sub>12</sub> receptor in complex with an antithrombotic drug.

Agonist-bound structure of the human P2Y<sub>12</sub> receptor.

Molecular control of δ-opioid receptor signalling.

Structure of the human glucagon class B G-protein-coupled receptor.

Structure of the human smoothened receptor bound to an antitumour agent.

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.

Structure of the human ?-opioid receptor in complex with JDTic.

Cover Feature: Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity (Chem. Eur. J. 47/2020).

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.

High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.

Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline.

Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases.

Sub-millisecond conformational dynamics of the A<sub>2A</sub> adenosine receptor revealed by single-molecule FRET.

The activation mechanism and antibody binding mode for orphan GPR20.