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A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
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- Cancer Cell International, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12935-023-02984-w
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- Article
Synthesis and Anticancer Evaluation of 4-Anilinoquinolinylchalcone Derivatives.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6034, doi. 10.3390/ijms24076034
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- Article
Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization.
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- Molecules, 2021, v. 26, n. 16, p. 4840, doi. 10.3390/molecules26164840
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- Article
Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators.
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- Molecules, 2020, v. 25, n. 14, p. 3133, doi. 10.3390/molecules25143133
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- Article
DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models.
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- Cancers, 2020, v. 12, n. 5, p. 1348, doi. 10.3390/cancers12051348
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- Article
Discovery of 2-Substituted 3-Arylquinoline Derivatives as Potential Anti-Inflammatory Agents Through Inhibition of LPS-Induced Inflammatory Responses in Macrophages.
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- Molecules, 2019, v. 24, n. 6, p. 1162, doi. 10.3390/molecules24061162
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- Article
Discovery of 3-Amino-2-Hydroxypropoxyisoflavone Derivatives as Potential Anti-HCV Agents.
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- Molecules, 2018, v. 23, n. 11, p. 2863, doi. 10.3390/molecules23112863
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- Article
Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3061, doi. 10.3390/ijms19103061
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- Article
Discovery of Pyrazolo[4,3-c]quinolines Derivatives as Potential Anti-Inflammatory Agents through Inhibiting of NO Production.
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- Molecules, 2018, v. 23, n. 5, p. 1036, doi. 10.3390/molecules23051036
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- Article
Cooperative Effects in Copper Polyamidoamine Dendrimer Complexes Catalyzing the Reduction of Molecular Oxygen.
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- European Journal of Inorganic Chemistry, 2016, v. 2016, n. 30, p. 4937, doi. 10.1002/ejic.201601144
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- Article
Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species.
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- Archivum Immunologiae & Therapiae Experimentalis, 2016, v. 64, n. 2, p. 139, doi. 10.1007/s00005-015-0368-4
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- Article
Cooperative Effects in Copper Polyamidoamine Dendrimer Complexes Catalyzing the Reduction of Molecular Oxygen.
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- European Journal of Inorganic Chemistry, 2015, v. 2015, n. 29, p. 4839, doi. 10.1002/ejic.201500540
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- Article
CFS-1686 Causes Cell Cycle Arrest at Intra-S Phase by Interference of Interaction of Topoisomerase 1 with DNA.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113832
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- Article
Inhibitory action of naphtho[1,2- b]furan-4,5-dione on hepatocyte growth factor-induced migration and invasion of MDA- MB-231 cells: Mechanisms of action.
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- Clinical & Experimental Pharmacology & Physiology, 2014, v. 41, n. 9, p. 716, doi. 10.1111/1440-1681.12272
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- Article
Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells.
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- Integrative Cancer Therapies, 2014, v. 13, n. 3, p. NP18, doi. 10.1177/1534735411433834
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- Article
Naphtho[1,2- b]furan-4,5-dione inhibits MDA-MB-231 cell migration and invasion by suppressing Src-mediated signaling pathways.
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- Molecular & Cellular Biochemistry, 2014, v. 387, n. 1/2, p. 101, doi. 10.1007/s11010-013-1875-4
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- Article
Discovery of indeno[1,2- $$c$$ ]quinoline derivatives as dual topoisomerases I/II inhibitors: Part 3.
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- Molecular Diversity, 2013, v. 17, n. 4, p. 781, doi. 10.1007/s11030-013-9475-5
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- Article
TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells.
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- Breast Cancer Research & Treatment, 2013, v. 138, n. 2, p. 383, doi. 10.1007/s10549-013-2441-1
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- Article
Combretastatin A-4 derivatives: synthesis and evaluation of 2,4,5-triaryl-1 H-imidazoles as potential agents against H1299 (non-small cell lung cancer cell).
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- Molecular Diversity, 2012, v. 16, n. 4, p. 697, doi. 10.1007/s11030-012-9396-8
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- Article
Identification of furo[3′, 2′:3,4]naphtho[1,2- d]imidazole derivatives as orally active and selective inhibitors of microsomal prostaglandin E synthase-1 (mPGES-1).
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- Molecular Diversity, 2012, v. 16, n. 2, p. 215, doi. 10.1007/s11030-011-9347-9
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- Article
Loss of IKKβ activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis.
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- Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 3, p. 687, doi. 10.1111/j.1582-4934.2009.00712.x
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- Article
Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells.
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- Journal of Biochemical & Molecular Toxicology, 2008, v. 22, n. 6, p. 396, doi. 10.1002/jbt.20254
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- Article
Synthesis and Antiproliferative Evaluation of 4-Anilino- n-methoxyfuro[2,3- b]quinoline Derivatives ( n=6, 7). Part 5.
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- Chemistry & Biodiversity, 2008, v. 5, n. 2, p. 267, doi. 10.1002/cbdv.200890024
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- Article
Induction of G2/M phase arrest and apoptosis by a novel indoloquinoline derivative, IQDMA, in K562 cells.
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- Drug Development Research, 2006, v. 67, n. 9, p. 743, doi. 10.1002/ddr.20113
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- Article
Synthesis and Cytotoxic Evaluation of Certain 4-(Phenylamino)furo[2,3- b]quinoline and 2-(Furan-2-yl)-4-(phenylamino)quinoline Derivatives.
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- Chemistry & Biodiversity, 2005, v. 2, n. 2, p. 205, doi. 10.1002/cbdv.200590003
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- Article
Synthesis and Cytotoxic Evaluation of Some 4-Anilinofuro[2,3- b]quinoline Derivatives.
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- Helvetica Chimica Acta, 2002, v. 85, n. 7, p. 2214, doi. 10.1002/1522-2675(200207)85:7<2214::AID-HLCA2214>3.0.CO;2-W
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- Article
Synthesis and Cytotoxic Activities of α-Methylidene- γ-butyrolactones Bearing a Quinolin-4(1 H)-one Moiety.
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- Helvetica Chimica Acta, 2001, v. 84, n. 4, p. 874, doi. 10.1002/1522-2675(20010418)84:4<874::AID-HLCA874>3.0.CO;2-I
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- Article
Synthesis and Cytotoxicity Evaluation of Certain α-Methylidene- γ-butyrolactones Bearing Coumarin, Flavone, Xanthone, Carbazole, and Dibenzofuran Moieties.
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- Helvetica Chimica Acta, 2000, v. 83, n. 5, p. 989, doi. 10.1002/(SICI)1522-2675(20000510)83:5<989::AID-HLCA989>3.0.CO;2-E
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- Article
Synthesis and Antiplatelet-Activity Evaluation of α-Methylidene- γ-butyrolactones Bearing 3,4-Dihydroquinolin-2(1 H)-one Moieties.
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- Helvetica Chimica Acta, 2000, v. 83, n. 2, p. 349, doi. 10.1002/(SICI)1522-2675(20000216)83:2<349::AID-HLCA349>3.0.CO;2-B
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- Article
Geiparvarin Analogues: Synthesis and Anticancer Evaluation of α-Methylidene- γ-butyrolactone-Bearing Coumarins.
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- Helvetica Chimica Acta, 1999, v. 82, n. 2, p. 191, doi. 10.1002/(SICI)1522-2675(19990210)82:2<191::AID-HLCA191>3.0.CO;2-P
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- Article
Synthesis and antibacterial activity of 1-(substituted-benzyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acids and their 6,8-difluoro analogs.
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- Journal of Heterocyclic Chemistry, 1998, v. 35, n. 4, p. 955, doi. 10.1002/jhet.5570350429
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- Article
α-Methylidene-γ-butyrolactones: Synthesis and evaluation of quinolin-2(1 H)-one derivatives.
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- Helvetica Chimica Acta, 1998, v. 81, n. 5-8, p. 1038, doi. 10.1002/hlca.19980810517
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- Article
Synthesis and Evaluation of α-Methylidene-γ-butyrolactone bearing flavone and xanthone moieties.
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- Helvetica Chimica Acta, 1997, v. 80, n. 8, p. 2337, doi. 10.1002/hlca.19970800806
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- Article
Synthesis and Evaluation of 2-{[(2-Oxo-1 H-quinolin-8-yl)oxy]methyl}-Substituted α-Methylidene-γ-butyrolactones.
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- Helvetica Chimica Acta, 1997, v. 80, n. 4, p. 1161, doi. 10.1002/hlca.19970800413
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- Article
Antiplatelet α-Methylidene-γ-butyrolactones: Synthesis and evaluation of quinoline, flavone, and xanthone derivatives.
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- Helvetica Chimica Acta, 1996, v. 79, n. 6, p. 1620, doi. 10.1002/hlca.19960790612
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- Article
Synthesis of Coumarin Derivatives as Inhibitors of Platelet Aggregation.
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- Helvetica Chimica Acta, 1996, v. 79, n. 3, p. 651, doi. 10.1002/hlca.19960790308
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- Article
Condensed as-triazines. Synthesis of 7-aryl-8 H-[1,4]thiazino[2,3- e]-1,2,4-triazin-3(2 H)-one.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 1, p. 293, doi. 10.1002/jhet.5570300152
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- Article