Found: 17
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Detecting LDoS Attacks based on Abnormal Network Traffic.
- Published in:
- KSII Transactions on Internet & Information Systems, 2012, v. 6, n. 7, p. 1831, doi. 10.3837/tiis.2012.07.007
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- Article
Adaptive EWMA Method Based on Abnormal Network Traffic for LDoS Attacks.
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- Mathematical Problems in Engineering, 2014, p. 1, doi. 10.1155/2014/496376
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- Article
Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455–456 synergistically enhances antibody evasion and ACE2 binding.
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- PLoS Pathogens, 2023, v. 19, n. 12, p. 1, doi. 10.1371/journal.ppat.1011868
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- Article
Transcoelomic spread of cancer cells across the peritoneal cavity occurs in most initially diagnosed ovarian cancer (OC) patients and accounts for most cancer-related death. However, how OC cells interact with peritoneal stromal cells to evade the immune surveillance remains largely unexplored. Here, through an in vivo genome-wide CRISPR/Cas9 screen, we identified IL20RA, which decreased dramatically in OC patients during peritoneal metastasis, as a key factor preventing the transcoelomic metastasis of OC. Reconstitution of IL20RA in highly metastatic OC cells greatly suppresses the transcoelomic metastasis. OC cells, when disseminate into the peritoneal cavity, greatly induce peritoneum mesothelial cells to express IL-20 and IL-24, which in turn activate the IL20RA downstream signaling in OC cells to produce mature IL-18, eventually resulting in the polarization of macrophages into the M1-like subtype to clear the cancer cells. Thus, we show an IL-20/IL20RA-mediated crosstalk between OC and mesothelial cells that supports a metastasis-repressing immune microenvironment.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.66222
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- Article
The impact of bitwise operators on hash uniformity in network packet processing.
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- International Journal of Communication Systems, 2014, v. 27, n. 11, p. 3158, doi. 10.1002/dac.2532
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- Article
DCBLD2 Mediates Epithelial-Mesenchymal Transition-Induced Metastasis by Cisplatin in Lung Adenocarcinoma.
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- Cancers, 2021, v. 13, n. 6, p. 1403, doi. 10.3390/cancers13061403
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- Article
PAX6/CXCL14 regulatory axis promotes the repair of corneal injury by enhancing corneal epithelial cell proliferation.
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- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05270-z
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- Article
Spirulina platensis alleviates chronic inflammation with modulation of gut microbiota and intestinal permeability in rats fed a high‐fat diet.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 15, p. 8603, doi. 10.1111/jcmm.15489
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- Article
A Mesoscale CFD Simulation Study of Basic Wind Pressure in Complex Terrain—A Case Study of Taizhou City.
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- Applied Sciences (2076-3417), 2022, v. 12, n. 20, p. N.PAG, doi. 10.3390/app122010481
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- Article
"M1/M2" Muscularis Macrophages Are Associated with Reduction of Interstitial Cells of Cajal and Glial Cells in Achalasia.
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- Digestive Diseases & Sciences, 2023, v. 68, n. 4, p. 1260, doi. 10.1007/s10620-022-07734-y
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- Article
Single-cell spatiotemporal analysis reveals alveolar dendritic cell–T cell immunity hubs defending against pulmonary infection.
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- Cell Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41421-024-00733-5
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- Article
Single-cell spatiotemporal analysis of the lungs reveals Slamf9<sup>+</sup> macrophages involved in viral clearance and inflammation resolution.
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- Cell Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41421-024-00734-4
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- Article
Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia.
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- Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0067-4
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- Article
Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia.
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- Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0067-4
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- Publication type:
- Article
Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents.
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- Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01237-y
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- Article
Generation of triacyl lipopeptide-modified glycoproteins by metabolic glycoengineering as the neoantigen to boost anti-tumor immune response.
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- Theranostics, 2021, v. 11, n. 15, p. 7425, doi. 10.7150/thno.60211
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- Article
Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer.
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- Theranostics, 2021, v. 11, n. 14, p. 6950, doi. 10.7150/thno.58956
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- Article