Works by Chen, Xiaojiang S.

Results: 38

Antigenic variations of recent street rabies virus.

Published in:

Emerging Microbes & Infections, 2019, v. 8, n. 1, p. 1584, doi. 10.1080/22221751.2019.1683436

By:

Wang, Wenbo;
Ma, Jian;
Nie, Jianhui;
Li, Jia;
Cao, Shouchun;
Wang, Lan;
Yu, Chuanfei;
Huang, Weijin;
Li, Yuhua;
Yu, Yongxin;
Liang, Mifang;
Zirkle, Brett;
Chen, Xiaojiang S.;
Li, Xuguang;
Kong, Wei;
Wang, Youchun

Publication type:

Article

Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45909-5

By:

Sanchez, Ambrocio;
Ortega, Pedro;
Sakhtemani, Ramin;
Manjunath, Lavanya;
Oh, Sunwoo;
Bournique, Elodie;
Becker, Alexandrea;
Kim, Kyumin;
Durfee, Cameron;
Temiz, Nuri Alpay;
Chen, Xiaojiang S.;
Harris, Reuben S.;
Lawrence, Michael S.;
Buisson, Rémi

Publication type:

Article

Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40955-x

By:

Ito, Fumiaki;
Alvarez-Cabrera, Ana L.;
Kim, Kyumin;
Zhou, Z. Hong;
Chen, Xiaojiang S.

Publication type:

Article

Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization.

Published in:

2017

By:

Tingting Ning;
Wolfe, Aaron;
Jianhui Nie;
Weijin Huang;
Chen, Xiaojiang S.;
Youchun Wang;
Ning, Tingting;
Nie, Jianhui;
Huang, Weijin;
Wang, Youchun

Publication type:

journal article

Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication.

Published in:

EMBO Journal, 2003, v. 22, n. 23, p. 6205, doi. 10.1093/emboj/cdg612

By:

Maria G. Gomez-Lorenzo;
Mikel Valle;
Joachim Frank;
Claudia Gruss;
Carlos Oscar S. Sorzano;
Xiaojiang S. Chen;
Luis Enrique Donate;
Jose Maria Carazo

Publication type:

Article

Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 447, doi. 10.1038/nsmb.2505

By:

Patrick, Aaron N;
Cabrera, Joshua H;
Smith, Anna L;
Chen, Xiaojiang S;
Ford, Heide L;
Zhao, Rui

Publication type:

Article

The structure of a DnaB-family replicative helicase and its interactions with primase.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 1, p. 94, doi. 10.1038/nsmb1356

By:

Ganggang Wang;
Klein, Michael G.;
Tokonzaba, Etienne;
Yi Zhang;
Holden, Lauren G.;
Xiaojiang S. Chen

Publication type:

Article

Structure of the Epstein-Barr virus major envelope glycoprotein.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 11, p. 996, doi. 10.1038/nsmb1161

By:

Szakonyi, Gerda;
Klein, Michael G.;
Hannan, Jonathan P.;
Young, Kendra A.;
Ma, Runlin Z.;
Asokan, Rengasamy;
Holers, V. Michael;
Chen, Xiaojiang S.

Publication type:

Article

A Computational Analysis of ATP Binding of SV40 Large Tumor Antigen Helicase Motor.

Published in:

PLoS Computational Biology, 2009, v. 5, n. 9, p. 1, doi. 10.1371/journal.pcbi.1000514

By:

Yemin Shi;
Hanbin Liu;
Dahai Gai;
Jianpeng Ma;
Xiaojiang S. Chen

Publication type:

Article

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.

Published in:

Nature, 2008, v. 456, n. 7218, p. 121, doi. 10.1038/nature07357

By:

Holden, Lauren G.;
Prochnow, Courtney;
Chang, Y. Paul;
Bransteitter, Ronda;
Chelico, Linda;
Sen, Udayaditya;
Stevens, Raymond C.;
Goodman, Myron F.;
Chen, Xiaojiang S.

Publication type:

Article

Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52671-1

By:

Yang, Hanjing;
Pacheco, Josue;
Kim, Kyumin;
Bokani, Ayub;
Ito, Fumiaki;
Ebrahimi, Diako;
Chen, Xiaojiang S.

Publication type:

Article

Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicaseactivity and DNA binding.

Published in:

BMC Molecular Biology, 2010, v. 11, p. 62, doi. 10.1186/1471-2199-11-62

By:

Brewster, Aaron S.;
Slaymaker, Ian M.;
Afif, Samir A.;
Chen, Xiaojiang S.

Publication type:

Article

DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.

Published in:

Biochemical Journal, 2015, v. 471, n. 1, p. 25, doi. 10.1042/BJ20150382

By:

Yang Fu;
Fumiaki Ito;
Gewen Zhang;
Fernandez, Braulio;
Hanjing Yang;
Chen, Xiaojiang S.

Publication type:

Article

Structural basis for Polθ-helicase DNA binding and microhomology-mediated end-joining.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58441-x

By:

Ito, Fumiaki;
Li, Ziyuan;
Minakhin, Leonid;
Khant, Htet A.;
Pomerantz, Richard T.;
Chen, Xiaojiang S.

Publication type:

Article

The current structural and functional understanding of APOBEC deaminases.

Published in:

Cellular & Molecular Life Sciences, 2009, v. 66, n. 19, p. 3137, doi. 10.1007/s00018-009-0070-y

By:

Bransteitter, Ronda;
Prochnow, Courtney;
Chen, Xiaojiang S.

Publication type:

Article

Study of SV40 large T antigen nucleotide specificity for DNA unwinding.

Published in:

Virology Journal, 2017, v. 14, p. 1, doi. 10.1186/s12985-017-0733-5

By:

Damian Wang;
Álvarez-Cabrera, Ana Lucia;
Chen, Xiaojiang S.

Publication type:

Article

The Helicase Activity of Hyperthermophilic Archaeal MCM is Enhanced at High Temperatures by Lysine Methylation.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.01247

By:

Yisui Xia;
Yanling Niu;
Jiamin Cui;
Yang Fu;
Chen, Xiaojiang S.;
Huiqiang Lou;
Qinhong Cao;
Clouet-D'Orval, Béatrice;
Meersman, Filip

Publication type:

Article

Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry.

Published in:

EMBO Journal, 1998, v. 17, n. 12, p. 3233, doi. 10.1093/emboj/17.12.3233

By:

Chen, Xiaojiang S.;
Stehle, Thilo;
Harrison, Stephen C.

Publication type:

Article

Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 12, p. 7494, doi. 10.1093/nar/gkx362

By:

Xiao, Xiao;
Yang, Hanjing;
Arutiunian, Vagan;
Fang, Yao;
Besse, Guillaume;
Morimoto, Cherie;
Zirkle, Brett;
Chen, Xiaojiang S.

Publication type:

Article

Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 5, p. 3446, doi. 10.1093/nar/gkt022

By:

Slaymaker, Ian M.;
Fu, Yang;
Toso, Daniel B.;
Ranatunga, Nimna;
Brewster, Aaron;
Forsburg, Susan L.;
Zhou, Z. Hong;
Chen, Xiaojiang S.

Publication type:

Article

Crystal structures of APOBEC3G N-domain alone and its complex with DNA.

Published in:

Nature Communications, 2016, v. 7, n. 8, p. 12193, doi. 10.1038/ncomms12193

By:

Xiao, Xiao;
Li, Shu-Xing;
Yang, Hanjing;
Chen, Xiaojiang S.

Publication type:

Article

The structure and function of MCM from archaeal M. Thermoautotrophicum.

Published in:

Nature Structural Biology, 2003, v. 10, n. 3, p. 160, doi. 10.1038/nsb893

By:

Fletcher, Ryan J.;
Bishop, Brooke E.;
Leon, Ronald P.;
Sclafani, Robert A.;
Ogata, Craig M.;
Chen, Xiaojiang S.

Publication type:

Article

Structure-based engineering of papillomavirus major capsid L1: controlling particle assembly.

Published in:

Virology Journal, 2007, v. 4, p. 3, doi. 10.1186/1743-422X-4-3

By:

Bishop, Brooke;
Dasgupta, Jhimli;
Chen, Xiaojiang S.

Publication type:

Article

The APOBEC-2 crystal structure and functional implications for the deaminase AID.

Published in:

Nature, 2007, v. 445, n. 7126, p. 447, doi. 10.1038/nature05492

By:

Prochnow, Courtney;
Bransteitter, Ronda;
Klein, Michael G.;
Goodman, Myron F.;
Chen, Xiaojiang S.

Publication type:

Article

corrigendum: Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen.

Published in:

2003

By:

Dawei Li;
Rui Zhao;
Lilyestrom, Wayne;
Dahai Gai;
Rongguang Zhang;
DiCaprio, James A.;
Fanning, Ellen;
Joachimiak, Andrzej;
Szakonyi, Gerda;
Chen, Xiaojiang S.

Publication type:

Correction Notice

Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen.

Published in:

Nature, 2003, v. 423, n. 6939, p. 512, doi. 10.1038/nature01691

By:

Li, Dawei;
Zhao, Rui;
Lilyestrom, Wayne;
Gai, Dahai;
Zhang, Rongguang;
DeCaprio, James A.;
Fanning, Ellen;
Jochimiak, Andrzej;
Szakonyi, Gerda;
Chen, Xiaojiang S.

Publication type:

Article

A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 3, p. 569

By:

Orrú, Valeria;
Tsai, Sophia J.;
Rueda, Blanca;
Fiorillo, Edoardo;
Stanford, Stephanie M.;
Dasgupta, Jhimli;
Hartiala, Jaana;
Zhao, Lei;
Ortego-Centeno, Norberto;
D’Alfonso, Sandra;
Arnett, Frank C.;
Wu, Hui;
Gonzalez-Gay, Miguel A.;
Tsao, Betty P.;
Pons-Estel, Bernardo;
Alarcon-Riquelme, Marta E.;
He, Yantao;
Zhang, Zhong-Yin;
Allayee, Hooman;
Chen, Xiaojiang S.

Publication type:

Article

Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14377-y

By:

Yang, Hanjing;
Ito, Fumiaki;
Wolfe, Aaron D.;
Li, Shuxing;
Mohammadzadeh, Nazanin;
Love, Robin P.;
Yan, Maocai;
Zirkle, Brett;
Gaba, Amit;
Chelico, Linda;
Chen, Xiaojiang S.

Publication type:

Article

Insights into the Structures and Multimeric Status of APOBEC Proteins Involved in Viral Restriction and Other Cellular Functions.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 3, p. 497, doi. 10.3390/v13030497

By:

Chen, Xiaojiang S.;
Melikian, Gregory B.

Publication type:

Article

Hexameric helicase G40P unwinds DNA in single base pair steps.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.42001.001

By:

Schlierf, Michael;
Ganggang Wang;
Chen, Xiaojiang S.;
Ha, Taekjip

Publication type:

Article

The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.18129

By:

Gai, Dahai;
Damian Wang;
Shu-Xing Li;
Chen, Xiaojiang S.

Publication type:

Article

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-19067-x

By:

Kim, Kyumin;
Calabrese, Peter;
Wang, Shanshan;
Qin, Chao;
Rao, Youliang;
Feng, Pinghui;
Chen, Xiaojiang S.

Publication type:

Article

Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35201-9

By:

Yang, Hanjing;
Kim, Kyumin;
Li, Shuxing;
Pacheco, Josue;
Chen, Xiaojiang S.

Publication type:

Article

DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity.

Published in:

Genes, 2021, v. 12, n. 8, p. 1146, doi. 10.3390/genes12081146

By:

Chen, Xiaojiang S.;
Pomerantz, Richard T.

Publication type:

Article

Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.

Published in:

Protein & Cell, 2024, v. 15, n. 7, p. 547, doi. 10.1093/procel/pwae009

By:

Ito, Fumiaki;
Yang, Hanjing;
Zhou, Z Hong;
Chen, Xiaojiang S

Publication type:

Article

A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization.

Published in:

Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-14

By:

Wenbo Wang;
Jianhui Nie;
Prochnow, Courtney;
Truong, Carolyn;
Zheng Jia;
Suting Wang;
Xiaojiang S. Chen;
Youchun Wang

Publication type:

Article

Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7.

Published in:

BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-5

By:

Xu, Meng;
Chang, Y. Paul;
Chen, Xiaojiang S.

Publication type:

Article

Insights into the MCM functional mechanism: lessons learned from the archaeal MCM complex.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2010, v. 45, n. 3, p. 243, doi. 10.3109/10409238.2010.484836

By:

Brewster, Aaron S.;
Chen, Xiaojiang S.

Publication type:

Article