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Carfilzomib induces leukaemia cell apoptosis via inhibiting ELK1/ KIAA1524 (Elk-1/ CIP2A) and activating PP2A not related to proteasome inhibition.
Published in:
British Journal of Haematology, 2017, v. 177, n. 5, p. 726, doi. 10.1111/bjh.14620
By:
- Liu, Chun‐Yu;
- Hsieh, Feng‐Shu;
- Chu, Pei‐Yi;
- Tsai, Wen‐Chun;
- Huang, Chun‐Teng;
- Yu, Yuan‐Bin;
- Huang, Tzu‐Ting;
- Ko, Po‐Shen;
- Hung, Man‐Hsin;
- Wang, Wan‐Lun;
- Shiau, Chung‐Wai;
- Chen, Kuen‐Feng
Publication type:
Article
Corrigendum: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.
Published in:
Scientific Reports, 2017, p. 45612, doi. 10.1038/srep45612
By:
- Teng, Hao-Wei;
- Hung, Man-Hsin;
- Chen, Li-Ju;
- Chang, Mao-Ju;
- Hsieh, Feng-Shu;
- Tsai, Ming-Hsien;
- Huang, Jui-Wen;
- Lin, Chih-Lung;
- Tseng, Hsiang-Wen;
- Kuo, Zong-Keng;
- Jiang, Jeng-Kai;
- Yang, Shung-Haur;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
Article
Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.
Published in:
Scientific Reports, 2016, p. 35308, doi. 10.1038/srep35308
By:
- Teng, Hao-Wei;
- Hung, Man-Hsin;
- Chen, Li-Ju;
- Chang, Mao-Ju;
- Hsieh, Feng-Shu;
- Tsai, Ming-Hsien;
- Huang, Jui-Wen;
- Lin, Chih-Lung;
- Tseng, Hsiang-Wen;
- Kuo, Zong-Keng;
- Jiang, Jeng-Kai;
- Yang, Shung-Haur;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
Article
Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis.
Published in:
Scientific Reports, 2016, p. 28888, doi. 10.1038/srep28888
By:
- Su, Jung-Chen;
- Mar, Ai-Chung;
- Wu, Szu-Hsien;
- Tai, Wei-Tien;
- Chu, Pei-Yi;
- Wu, Chia-Yun;
- Tseng, Ling-Ming;
- Lee, Te-Chang;
- Chen, Kuen-Feng;
- Liu, Chun-Yu;
- Chiu, Hao-Chieh;
- Shiau, Chung-Wai
Publication type:
Article
Cancerous Inhibitor of Protein Phosphatase 2A Mediates Bortezomib-Induced Autophagy in Hepatocellular Carcinoma Independent of Proteasome.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055705
By:
- Yu, Hui-Chuan;
- Hou, Duen-Ren;
- Liu, Chun-Yu;
- Lin, Chen-Si;
- Shiau, Chung-Wai;
- Cheng, Ann-Lii;
- Chen, Kuen-Feng
Publication type:
Article
Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.
Published in:
2017
By:
- Liu, Chun-Yu;
- Tseng, Ling-Ming;
- Su, Jung-Chen;
- Chang, Kung-Chi;
- Chu, Pei-Yi;
- Tai, Wei-Tien;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
journal article
Serine/threonine protein phosphatase 5 is a potential therapeutic target in cholangiocarcinoma.
Published in:
Liver International, 2018, v. 38, n. 12, p. 2248, doi. 10.1111/liv.13887
By:
- Kao, Jia‐Horng;
- Hu, Ming‐Hung;
- Huang, Tzu‐Ting;
- Liu, Chun‐Yu;
- Chao, Tzu‐I;
- Chen, Li‐Ju;
- Tsai, Ming‐Hsien;
- Chen, Kuen‐Feng;
- Chen, Yen‐Lin
Publication type:
Article
Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells.
Published in:
Breast Cancer Research & Treatment, 2014, v. 146, n. 1, p. 71, doi. 10.1007/s10549-014-3000-0
By:
- Liu, Chun-Yu;
- Su, Jung-Chen;
- Ni, Mei-Huei;
- Tseng, Ling-Ming;
- Chu, Pei-Yi;
- Wang, Duen-Shian;
- Tai, Wei-Tien;
- Kao, Yuan-Ping;
- Hung, Man-Hsin;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
Article
Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells.
Published in:
2014
By:
- Liu, Chun-Yu;
- Hung, Man-Hsin;
- Wang, Duen-Shian;
- Chu, Pei-Yi;
- Su, Jung-Chen;
- Teng, Tsung-Han;
- Huang, Chun-Teng;
- Chao, Ting-Ting;
- Wang, Cheng-Yi;
- Shiau, Chung-Wai;
- Tseng, Ling-Ming;
- Chen, Kuen-Feng
Publication type:
journal article
Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.
Published in:
2013
By:
- Liu, Chun-Yu;
- Tseng, Ling-Ming;
- Su, Jung-Chen;
- Chang, Kung-Chi;
- Chu, Pei-Yi;
- Tai, Wei-Tien;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
journal article
CIP2A is a target of bortezomib in human triple negative breast cancer cells.
Published in:
2012
By:
- Tseng, Ling-Ming;
- Liu, Chun-Yu;
- Chang, Kung-Chi;
- Chu, Pei-Yi;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng
Publication type:
journal article
RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells.
Published in:
Carcinogenesis, 2014, v. 35, n. 12, p. 2807
By:
- Su, Jung-Chen;
- Chiang, Heng-Chieh;
- Tseng, Ping-Hui;
- Tai, Wei-Tien;
- Hsu, Cheng-Yi;
- Li, Yong-Shi;
- Huang, Jui-Wen;
- Ko, Ching-Huai;
- Lin, Mai-Wei;
- Chu, Pei-Yi;
- Liu, Chun-Yu;
- Chen, Kuen-Feng;
- Shiau, Chung-Wai
Publication type:
Article
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Published in:
Cell Death & Disease, 2019, v. 10, n. 6, p. N.PAG, doi. 10.1038/s41419-019-1646-6
By:
- Hung, Man-Hsin;
- Chen, Yao-Li;
- Chen, Li-Ju;
- Chu, Pei-Yi;
- Hsieh, Feng-Shu;
- Tsai, Ming-Hsien;
- Shih, Chih-Ting;
- Chao, Tzu-I;
- Huang, Chao-Yuan;
- Chen, Kuen-Feng
Publication type:
Article
Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody.
Published in:
British Journal of Pharmacology, 2013, v. 168, n. 3, p. 658, doi. 10.1111/j.1476-5381.2012.02212.x
By:
- Chen, Kuen‐Feng;
- Chen, Hui‐Ling;
- Shiau, Chung‐Wai;
- Liu, Chun‐Yu;
- Chu, Pei‐Yi;
- Tai, Wei‐Tien;
- Ichikawa, Kimihisa;
- Chen, Pei‐Jer;
- Cheng, Ann‐Lii
Publication type:
Article
Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.
Published in:
Journal of Molecular Medicine, 2017, v. 95, n. 9, p. 965, doi. 10.1007/s00109-017-1549-x
By:
- Liu, Chun-Yu;
- Chen, Kuen-Feng;
- Chao, Tzu-I;
- Chu, Pei-Yi;
- Huang, Chun-Teng;
- Huang, Tzu-Ting;
- Yang, Hsiu-Ping;
- Wang, Wan-Lun;
- Lee, Chia-Han;
- Lau, Ka-Yi;
- Tsai, Wen-Chun;
- Su, Jung-Chen;
- Wu, Chia-Yun;
- Chen, Ming-Huang;
- Shiau, Chung-Wai;
- Tseng, Ling-Ming
Publication type:
Article
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Published in:
2015
By:
- Chen, Kuen-Feng;
- Yen, Chueh-Chuan;
- Lin, Jen-Kou;
- Chen, Wei-Shone;
- Yang, Shung-Haur;
- Jiang, Jeng-Kai;
- Lan, Yuan-Tzu;
- Lin, Chun-Chi;
- Yu, Hui-Chuan;
- Hsu, Hui-Mei;
- Lin, Wen-Ling;
- Teng, Hao-Wei
Publication type:
journal article
Sorafenib Action in Hepatitis B Virus X-Activated Oncogenic Androgen Pathway in Liver through SHP-1.
Published in:
2015
By:
- Sheng-Han Wang;
- Shiou-Hwei Yeh;
- Chung-Wai Shiau;
- Kuen-Feng Chen;
- Wei-Hsiang Lin;
- Ting-Fen Tsai;
- Yuan-Chi Teng;
- Ding-Shinn Chen;
- Pei-Jer Chen;
- Wang, Sheng-Han;
- Yeh, Shiou-Hwei;
- Shiau, Chung-Wai;
- Chen, Kuen-Feng;
- Lin, Wei-Hsiang;
- Tsai, Ting-Fen;
- Teng, Yuan-Chi;
- Chen, Ding-Shinn;
- Chen, Pei-Jer
Publication type:
journal article
Sorafenib analogue SC-60 induces apoptosis through the SHP-1/ STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells.
Published in:
Molecular Oncology, 2017, v. 11, n. 3, p. 266, doi. 10.1002/1878-0261.12033
By:
- Liu, Chun‐Yu;
- Su, Jung‐Chen;
- Huang, Tzu‐Ting;
- Chu, Pei‐Yi;
- Huang, Chun‐Teng;
- Wang, Wan‐Lun;
- Lee, Chia‐Han;
- Lau, Ka‐Yi;
- Tsai, Wen‐Chun;
- Yang, Hsiu‐Ping;
- Shiau, Chung‐Wai;
- Tseng, Ling‐Ming;
- Chen, Kuen‐Feng
Publication type:
Article
SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells.
Published in:
Journal of Orthopaedic Research, 2013, v. 31, n. 2, p. 335, doi. 10.1002/jor.22218
By:
- Wang, Chen‐Ti;
- Lin, Chen‐Si;
- Shiau, Chung‐Wai;
- Chu, Pei‐Yi;
- Hsiao, Chung‐Ching;
- Chiang, Yi‐Lun;
- Tai, Wei‐Tien;
- Chen, Kuen‐Feng
Publication type:
Article

Found: 19