Works by Chen, Horng H.

Results: 44

Dopamine vs nesiritide for acute heart failure with renal dysfunction--reply.
Published in:
2014
By:
- Chen, Horng H;
- Redfield, Margaret M
Publication type:
commentary
Dopamine vs Nesiritide for Acute Heart Failure With Renal Dysfunction.
Published in:
2014
By:
- Chen, Horng H.;
- Redfield, Margaret M.
Publication type:
Letter to the Editor
Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.
Published in:
2013
By:
- Chen, Horng H;
- Anstrom, Kevin J;
- Givertz, Michael M;
- Stevenson, Lynne W;
- Semigran, Marc J;
- Goldsmith, Steven R;
- Bart, Bradley A;
- Bull, David A;
- Stehlik, Josef;
- LeWinter, Martin M;
- Konstam, Marvin A;
- Huggins, Gordon S;
- Rouleau, Jean L;
- O'Meara, Eileen;
- Tang, W H Wilson;
- Starling, Randall C;
- Butler, Javed;
- Deswal, Anita;
- Felker, G Michael;
- O'Connor, Christopher M
Publication type:
journal article
Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction.
Published in:
JAMA: Journal of the American Medical Association, 2013, v. 310, n. 23, p. 2533, doi. 10.1001/jama.2013.282190
By:
- Horng H. Chen;
- Anstrom, Kevin J.;
- Givertz, Michael M.;
- Stevenson, Lynne W.;
- Semigran, Marc J.;
- Goldsmith, Steven R.;
- Bart, Bradley A.;
- Bull, David A.;
- Stehlik, Josef;
- LeWinter, Martin M.;
- Konstam, Marvin A.;
- Huggins, Gordon S.;
- Rouleau, Jean L.;
- O'Meara, Eileen;
- Wilson Tang, W. H.;
- Starling, Randall C.;
- Butler, Javed;
- Deswal, Anita;
- Felker, G. Michael;
- O'Connor, Christopher M.
Publication type:
Article
Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial.
Published in:
2013
By:
- Redfield, Margaret M;
- Chen, Horng H;
- Borlaug, Barry A;
- Semigran, Marc J;
- Lee, Kerry L;
- Lewis, Gregory;
- LeWinter, Martin M;
- Rouleau, Jean L;
- Bull, David A;
- Mann, Douglas L;
- Deswal, Anita;
- Stevenson, Lynne W;
- Givertz, Michael M;
- Ofili, Elizabeth O;
- O'Connor, Christopher M;
- Felker, G Michael;
- Goldsmith, Steven R;
- Bart, Bradley A;
- McNulty, Steven E;
- Ibarra, Jenny C
Publication type:
journal article
Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction.
Published in:
JAMA: Journal of the American Medical Association, 2013, v. 309, n. 12, p. 1268, doi. 10.1001/jama.2013.2024
By:
- Redfield, Margaret M.;
- Chen, Horng H.;
- Borlaug, Barry A.;
- Semigran, Marc J.;
- Lee, Kerry L.;
- Lewis, Gregory;
- LeWinter, Martin M.;
- Bouleau, Jean L.;
- Bull, David A.;
- Mann, Douglas L.;
- Deswal, Anita;
- Stevenson, Lynne W.;
- Givertz, Michael M.;
- Ofili, Elizabeth O.;
- O'Connor, Christopher M.;
- Felker, G. Michael;
- Goldsmith, Steven B.;
- Bart, Bradley A.;
- McNulty, Steven E.;
- Ibarra, Jenny C.
Publication type:
Article
Acute oral pegylated human BNP activates cGMP and decreases mean arterial pressure in normal dogs
Published in:
2005
By:
- Cataliotti, Alessandro;
- Schirger, John A.;
- Martin, Fernando L.;
- Chen, Horng H.;
- James, Kenneth D.;
- Miller, Mark A.;
- Malkar, Navdeep B.;
- Ekwuribe, Nnoch N.;
- Burnett, John C.
Publication type:
Abstract
BNP enhances renal actions of lasix and suppresses lasix-induced aldosterone activation in experimental heart failure
Published in:
2003
By:
- Cataliotti, Alessandro;
- Boerrigter, Guido;
- Costello-Boerrigter, Lisa C.;
- Tsuruda, Toshihiro;
- Schirger, John A.;
- Chen, Horng H.;
- Malatino, Lorenzo S.;
- Burnett Jr, John C.
Publication type:
Abstract
Effects of phosphodiesterase V inhibition alone and in combination with BNP on cardiovascular and renal response to volume load in human preclinical diastolic dysfunction.
Published in:
Physiological Reports, 2021, v. 9, n. 16, p. 1, doi. 10.14814/phy2.14974
By:
- Wan, Siu‐Hin;
- McKie, Paul M.;
- Slusser, Joshua P.;
- Burnett, John C.;
- Hodge, David O.;
- Chen, Horng H.
Publication type:
Article
Natriuretic peptide pathways in heart failure: further therapeutic possibilities.
Published in:
Cardiovascular Research, 2022, v. 118, n. 18, p. 3416, doi. 10.1093/cvr/cvac125
By:
- Sangaralingham, S Jeson;
- Kuhn, Michaela;
- Cannone, Valentina;
- Chen, Horng H;
- Burnett, John C
Publication type:
Article
B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts.
Published in:
Journal of Cellular Physiology, 2010, v. 225, n. 1, p. 251, doi. 10.1002/jcp.22253
By:
- HUNTLEY, BRENDA K.;
- ICHIKI, TOMOKO;
- SANGARALINGHAM, S. JESON;
- CHEN, HORNG H.;
- BURNETT JR., JOHN C.
Publication type:
Article
Natriuretic peptide levels and predicting risk of developing new diabetes mellitus and metabolic syndrome.
Published in:
Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 777, doi. 10.1111/dom.16073
By:
- Singh, Jasraj;
- Adel, Fadi W.;
- Scott, Christopher G.;
- Chen, Horng H.
Publication type:
Article
The role of multimodality imaging in diabetic cardiomyopathy: a brief review.
Published in:
Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2024.1405031
By:
- Adel, Fadi W.;
- Chen, Horng H.
Publication type:
Article
Renal actions of synthetic Dendroaspis natriuretic peptide.
Published in:
Kidney International, 1999, v. 56, n. 2, p. 502, doi. 10.1046/j.1523-1755.1999.00573.x
By:
- Lisy, Ondrej;
- Jougasaki, Michihisa;
- Heublein, Denise M.;
- Schirger, John A.;
- Chen, Horng H.;
- Wennberg, Paul W.;
- Burnett, John C.
Publication type:
Article
Implications of peripheral oedema in heart failure with preserved ejection fraction: a heart failure network analysis.
Published in:
ESC Heart Failure, 2021, v. 8, n. 1, p. 662, doi. 10.1002/ehf2.13159
By:
- Fudim, Marat;
- Ashur, Nicolas;
- Jones, Aaron D.;
- Ambrosy, Andrew P.;
- Bart, Bradley A.;
- Butler, Javed;
- Chen, Horng H.;
- Greene, Stephen J.;
- Reddy, Yogesh;
- Redfield, Margaret M.;
- Sharma, Abhinav;
- Hernandez, Adrian F.;
- Felker, Gary Michael;
- Borlaug, Barry A.;
- Mentz, Robert J.
Publication type:
Article
The Importance of Natriuretic Peptides in Cardiometabolic Diseases.
Published in:
Journal of the Endocrine Society, 2020, v. 4, n. 6, p. 1, doi. 10.1210/jendso/bvaa052
By:
- Vinnakota, Shravya;
- Chen, Horng H
Publication type:
Article
Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.
Published in:
2018
By:
- Borlaug, Barry A.;
- Anstrom, Kevin J.;
- Lewis, Gregory D.;
- Shah, Sanjiv J.;
- Levine, James A.;
- Koepp, Gabe A.;
- Givertz, Michael M.;
- Felker, G. Michael;
- LeWinter, Martin M.;
- Mann, Douglas L.;
- Margulies, Kenneth B.;
- Smith, Andrew L.;
- Tang, W. H. Wilson;
- Whellan, David J.;
- Chen, Horng H.;
- Davila-Roman, Victor G.;
- McNulty, Steven;
- Desvigne-Nickens, Patrice;
- Hernandez, Adrian F.;
- Braunwald, Eugene
Publication type:
journal article
Pharmacodynamics of a Novel Designer Natriuretic Peptide, CD-NP, in a First-in-Human Clinical Trial in Healthy Subjects.
Published in:
Journal of Clinical Pharmacology, 2010, v. 50, n. 6, p. 668, doi. 10.1177/0091270009336233
By:
- Lee, Candace Y. W.;
- Chen, Horng H.;
- Lisy, Ondrej;
- Swan, Suzanne;
- Cannon, Courtney;
- Lieu, Hsiao D.;
- Burnett Jr., John C.
Publication type:
Article
Pharmacodynamics of a Novel Designer Natriuretic Peptide, CD-NP, in a First-in-Human Clinical Trial in Healthy Subjects.
Published in:
Journal of Clinical Pharmacology, 2009, v. 49, n. 6, p. 668, doi. 10.1177/0091270009336233
By:
- Lee, Candace Y. W.;
- Chen, Horng H.;
- Lisy, Ondrej;
- Swan, Suzanne;
- Cannon, Courtney;
- Lieu, Hsiao D.;
- Burnett Jr., John C.
Publication type:
Article
Biomarker-based risk prediction in the community.
Published in:
European Journal of Heart Failure. Supplements, 2016, v. 18, n. 11, p. 1342, doi. 10.1002/ejhf.663
By:
- Abou Ezzeddine, Omar F.;
- Mckie, Paul M.;
- Scott, Christopher G.;
- Rodeheffer, Richard J.;
- Chen, Horng H.;
- Felker, G. Michael;
- Jaffe, Allan S.;
- Burnett, John C.;
- Redfield, Margaret M.
Publication type:
Article
Effect of cardiac resynchronization therapy on broad neurohormone biomarkers in heart failure.
Published in:
Journal of Interventional Cardiac Electrophysiology, 2011, v. 30, n. 3, p. 241, doi. 10.1007/s10840-011-9551-7
By:
- Ying-xue Dong;
- Burnett Jr., John C.;
- Chen, Horng H.;
- Sandberg, Sharon;
- Yan-zhong Yang;
- Yanhua Zhang;
- Peng-Sheng Chen;
- Yong-Mei Cha
Publication type:
Article
Suppression of Tumorigenicity 2 in Heart Failure With Preserved Ejection Fraction.
Published in:
2017
By:
- AbouEzzeddine, Omar F.;
- McKie, Paul M.;
- Dunlay, Shannon M.;
- Stevens, Susanna R.;
- Felker, G. Michael;
- Borlaug, Barry A.;
- Chen, Horng H.;
- Tracy, Russell P.;
- Braunwald, Eugene;
- Redfield, Margaret M.
Publication type:
journal article
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
Published in:
2014
By:
- McKie, Paul M;
- Cataliotti, Alessandro;
- Ichiki, Tomoko;
- Sangaralingham, S Jeson;
- Chen, Horng H;
- Burnett, John C;
- Burnett, John C Jr
Publication type:
journal article
Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8547, doi. 10.3390/ijms24108547
By:
- Ma, Xiao;
- Iyer, Seethalakshmi R.;
- Ma, Xiaoyu;
- Reginauld, Shawn H.;
- Chen, Yang;
- Pan, Shuchong;
- Zheng, Ye;
- Moroni, Dante G.;
- Yu, Yue;
- Zhang, Lianwen;
- Cannone, Valentina;
- Chen, Horng H.;
- Ferrario, Carlos M.;
- Sangaralingham, S. Jeson;
- Burnett Jr., John C.
Publication type:
Article
Cardiac resynchronization therapy improves myocardial conduction.
Published in:
Pacing & Clinical Electrophysiology, 2019, v. 42, n. 2, p. 238, doi. 10.1111/pace.13581
By:
- Yang, Mei;
- Li, Xuping;
- Yang, Dachun;
- Li, Yigang;
- Zhou, Shenghua;
- Liang, Jinjun;
- Wu, Gang;
- Del‐Carpio Munoz, Freddy;
- Chen, Horng H.;
- Friedman, Paul A.;
- Cha, Yong‐Mei
Publication type:
Article
Cenderitide, a novel dual GC-A and GC-B receptor activator, is a potent chronic cardiorenal fibroinhibiting peptide which suppresses aldosterone and reduces proteinuria in models of ardiorenal fibrosis.
Published in:
2011
By:
- Martin, Fernando L.;
- McKie, Paul M.;
- Sangaralingham, Jeson S.;
- Ichiki, Tomoko;
- Harders, Gerald E.;
- Chen, Horng H.;
- Burnett, Jr, John C.
Publication type:
Abstract
Treatment with CBA-NP a novel chimeric natriuretic peptide attenuates cardiorenal fibrosis and improves diastolic dysfunction in diabetic rat model.
Published in:
2011
By:
- Ameenuddin, Syed;
- Oehler, Elise A.;
- Burnett, Jr, John C.;
- Chen, Horng H.
Publication type:
Abstract
Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure
Published in:
2011
By:
- Costello-Boerrigter, Lisa C.;
- Schirger, John A.;
- Miller, Wayne L.;
- Boerrigter, Guido;
- Chen, Horng H.;
- Kempf, Ruth;
- Lee, Candace Y.;
- Burnett, Jr, John C.
Publication type:
Abstract
Incidence of Preclinical Heart Failure in a Community Population.
Published in:
2022
By:
- Young, Kathleen A.;
- Scott, Christopher G.;
- Rodeheffer, Richard J.;
- Chen, Horng H.
Publication type:
journal article
Cardiorenal Effects of Long-Term Phosphodiesterase V Inhibition in Pre-Heart Failure.
Published in:
2022
By:
- Hubers, Scott A.;
- Siu-Hin Wan;
- Adel, Fadi W.;
- Benike, Sherry L.;
- Burnett Jr, John C.;
- Scott, Christopher;
- Chen, Horng H.;
- Wan, Siu-Hin;
- Burnett, John C Jr
Publication type:
journal article
Assessing intrinsic renal sodium avidity in acute heart failure: implications in predicting and guiding decongestion.
Published in:
European Journal of Heart Failure, 2022, v. 24, n. 10, p. 1978, doi. 10.1002/ejhf.2662
By:
- Martens, Pieter;
- Chen, Horng H.;
- Verbrugge, Frederik H.;
- Testani, Jeffrey T.;
- Mullens, Wilfried;
- Tang, W.H. Wilson
Publication type:
Article
Biomarker-based risk prediction in the community.
Published in:
2016
By:
- AbouEzzeddine, Omar F.;
- McKie, Paul M.;
- Scott, Christopher G.;
- Rodeheffer, Richard J.;
- Chen, Horng H.;
- Michael Felker, G.;
- Jaffe, Allan S.;
- Burnett, John C.;
- Redfield, Margaret M.
Publication type:
journal article
Chronic subcutaneous brain natriuretic peptide therapy in asymptomatic systolic heart failure.
Published in:
2016
By:
- McKie, Paul M.;
- Schirger, John A.;
- Benike, Sherry L.;
- Harstad, Lynn K.;
- Slusser, Joshua P.;
- Hodge, David O.;
- Redfield, Margaret M.;
- Burnett, John C.;
- Chen, Horng H.
Publication type:
journal article
Intact acute cardiorenal and humoral responsiveness following chronic subcutaneous administration of the cardiac peptide BNP in experimental heart failure
Published in:
European Journal of Heart Failure, 2006, v. 8, n. 7, p. 681, doi. 10.1016/j.ejheart.2005.12.005
By:
- Chen, Horng H.;
- Schirger, John A.;
- Cataliotti, Alessandro;
- Burnett, John C.
Publication type:
Article
Leukemia inhibitory factor is augmented in the heart in experimental heart failure
Published in:
2003
By:
- Jougasaki, Michihisa;
- Leskinen, Hanna;
- Larsen, Amy M.;
- Cataliotti, Alessandro;
- Chen, Horng H.;
- Burnett Jr., John C.;
- Burnett, John C Jr
Publication type:
journal article
The modulating actions of sulfonylurea on atrial natriuretic peptide release in experimental acute heart failure.
Published in:
2000
By:
- Chen, Horng H.;
- Oh, Karen Y.;
- Terzic, Andre;
- Burnett, John C.;
- Chen, H H;
- Oh, K Y;
- Terzic, A;
- Burnett, J C Jr
Publication type:
journal article
M-atrial natriuretic peptide and nitroglycerin in experimental acute hypertensive heart failure: differential actions of two cGMP activating therapeutics.
Published in:
2013
By:
- McKie, Paul M.;
- Cataliotti, Alessandro;
- Ichiki, Tomoko;
- Jeson Sangaralingham, S.;
- Horng H Chen;
- Burnett Jr, John C.
Publication type:
Abstract
Chronic natriuretic peptide protein therapeutics.
Published in:
2013
By:
- Chen, Horng H.;
- Cataliotti, Alessandro;
- Burnett Jr, John C.
Publication type:
Abstract
Insulin Therapy is Associated With Increased Myocardial Interstitial Fibrosis and Cardiomyocyte Apoptosis in a Rodent Model of Experimental Diabetes.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.890907
By:
- Adel, Fadi W.;
- Zheng, Ye;
- Wan, Siu-Hin;
- Greason, Christie;
- Pan, Shuchong;
- Ameenuddin, Syed;
- Chen, Horng H.
Publication type:
Article
Cell Surface Protein Disulfide Isomerase Regulates Natriuretic Peptide Generation of Cyclic Guanosine Monophosphate.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112986
By:
- Pan, Shuchong;
- Chen, Horng H.;
- Correia, Cristina;
- Dai, Haiming;
- Witt, Tyra A.;
- Kleppe, Laurel S.;
- JrBurnett, John C.;
- Simari, Robert D.
Publication type:
Article
Cenderitide-Eluting Film for Potential Cardiac Patch Applications.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068346
By:
- Ng, Xu Wen;
- Huang, Yingying;
- Chen, Horng H.;
- Burnett Jr, John C.;
- Boey, Freddy Y. C.;
- Venkatraman, Subbu S.
Publication type:
Article
In-Vivo Evaluation of an In Situ Polymer Precipitation Delivery System for a Novel Natriuretic Peptide.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0052484
By:
- Lim, Soo Ghim;
- Venkatraman, Subbu S.;
- Burnett Jr, John C.;
- Chen, Horng H.
Publication type:
Article
CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052422
By:
- Martin, Fernando L.;
- Sangaralingham, S. Jeson;
- Huntley, Brenda K.;
- McKie, Paul M.;
- Ichiki, Tomoko;
- Chen, Horng H.;
- Korinek, Josef;
- Harders, Gerald E.;
- Burnett Jr., John C.
Publication type:
Article
A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure.
Published in:
Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 3, p. 546, doi. 10.1002/cpt.974
By:
- Kawakami, Rika;
- Lee, Candace Y. W.;
- Schirger, John A.;
- Chen, Horng H.;
- Benike, Sherry L.;
- Martin, Fernando L.;
- Sangaralingham, S. Jeson;
- Ichiki, Tomoko;
- Burnett, Jr., John C.;
- Cannone, Valentina;
- Scott, Christopher;
- Bailey, Kent R.
Publication type:
Article