Works by Chen, Chunnuan

Results: 38

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury.

Published in:

2017

By:

Xiangrong Chen;
Shukai Wu;
Chunnuan Chen;
Baoyuan Xie;
Zhongning Fang;
Weipeng Hu;
Junyan Chen;
Huangde Fu;
Hefan He;
Chen, Xiangrong;
Wu, Shukai;
Chen, Chunnuan;
Xie, Baoyuan;
Fang, Zhongning;
Hu, Weipeng;
Chen, Junyan;
Fu, Huangde;
He, Hefan

Publication type:

journal article

Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02709-x

By:

Zhuang, Jianlong;
Fu, Wanyu;
Gu, Ling;
Ye, Xiaofang;
Wang, Junyu;
Chen, Chunnuan

Publication type:

Article

Association of ApoB/apoA1 ratio with stenosis of intracranial and extracranial arteries in patients with ischaemic stroke.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-97625-9

By:

Li, Mimi;
Ye, Lichao;
Chen, Chunnuan

Publication type:

Article

Prenatal diagnosis of fetuses with 15q11.2 BP1-BP2 microdeletion in the Chinese population: a seven-year single-center retrospective study.

Published in:

2024

By:

Zhuang, Jianlong;
Zhang, Na;
Fu, Wanyu;
Jiang, Yuying;
Chen, Yu'e;
Chen, Chunnuan

Publication type:

Case Study

Identification of a novel isolated 4q35.2 microdeletion in a Chinese pediatric patient using chromosomal microarray analysis: a case report and literature review.

Published in:

2023

By:

Zhuang, Jianlong;
Liu, Shufen;
Chen, Xinying;
Jiang, Yuying;
Chen, Chunnuan

Publication type:

Case Study

Identification of partial trisomy 13q in two unrelated patients using single-nucleotide polymorphism array and literature overview.

Published in:

Molecular Cytogenetics (17558166), 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13039-022-00608-y

By:

Zhuang, Jianlong;
Chen, Chunnuan;
Zhang, Hegan;
Fu, Wanyu;
Li, Yanqing;
Jiang, Yuying;
Zeng, Shuhong;
Wu, Xiaoxia;
Xie, Yingjun;
Wang, Gaoxiong

Publication type:

Article

Molecular cytogenetic analysis of partial monosomy 10p and trisomy 10q resulting from familial pericentric inversion (10): a first case report in Chinese population.

Published in:

Molecular Cytogenetics (17558166), 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13039-022-00599-w

By:

Zhuang, Jianlong;
Chen, Chunnuan;
Huang, Rongfu;
Luo, Qi;
Jiang, Yuying;
Zeng, Shuhong;
Wang, Yuanbai;
Xie, Yingjun

Publication type:

Article

VisANT 3.0: new modules for pathway visualization, editing, prediction and construction.

Published in:

Nucleic Acids Research, 2007, v. 35, n. suppl_2, p. W625, doi. 10.1093/nar/gkm295

By:

Hu, Zhenjun;
Ng, David M.;
Yamada, Takuji;
Chen, Chunnuan;
Kawashima, Shuichi;
Mellor, Joe;
Linghu, Bolan;
Kanehisa, Minoru;
Stuart, Joshua M.;
DeLisi, Charles

Publication type:

Article

Allele quantification using molecular inversion probes (MIP).

Published in:

Nucleic Acids Research, 2005, v. 33, n. 21, p. e183, doi. 10.1093/nar/gni177

By:

Wang, Yuker;
Moorhead, Martin;
Karlin-Neumann, George;
Falkowski, Matthew;
Chen, Chunnuan;
Siddiqui, Farooq;
Davis, Ronald W.;
Willis, Thomas D.;
Faham, Malek

Publication type:

Article

Identification of HIVEP2 as a dopaminergic transcription factor related to substance use disorders in rats and humans.

Published in:

Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0573-8

By:

Zhao, Juan;
Chen, Chunnuan;
Bell, Richard L.;
Qing, Hong;
Lin, Zhicheng

Publication type:

Article

A de novo PAK1 likely pathogenic variant and a de novo terminal 1q microdeletion in a Chinese girl with global developmental delay, severe intellectual disability, and seizures.

Published in:

BMC Medical Genomics, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s12920-023-01433-x

By:

Zhuang, Jianlong;
Xie, Meihua;
Yao, Jianfeng;
Fu, Wanyu;
Zeng, Shuhong;
Jiang, Yuying;
Wang, Yuanbai;
Xie, Yingjun;
Wang, Gaoxiong;
Chen, Chunnuan

Publication type:

Article

A de novo PAK1 likely pathogenic variant and a de novo terminal 1q microdeletion in a Chinese girl with global developmental delay, severe intellectual disability, and seizures.

Published in:

2023

By:

Zhuang, Jianlong;
Xie, Meihua;
Yao, Jianfeng;
Fu, Wanyu;
Zeng, Shuhong;
Jiang, Yuying;
Wang, Yuanbai;
Xie, Yingjun;
Wang, Gaoxiong;
Chen, Chunnuan

Publication type:

Case Study

Third-Generation Sequencing as a New Comprehensive Technology for Identifying Rare α- and β-Globin Gene Variants in Thalassemia Alleles in the Chinese Population.

Published in:

Archives of Pathology & Laboratory Medicine, 2023, v. 147, n. 2, p. 208, doi. 10.5858/arpa.2021-0510-OA

By:

Jianlong Zhuang;
Chunnuan Chen;
Wanyu Fu;
Yuanbai Wang;
Qianmei Zhuang;
Yulin Lu;
Tiantian Xie;
Ruofan Xu;
Shuhong Zeng;
Yuying Jiang;
Yingjun Xie;
Gaoxiong Wang

Publication type:

Article

Case Report: Prenatal Diagnosis of a Novel Variant c.251dupT (p.N87Kfs*6) in BCOR Resulting in Oculofaciocardiodental Syndrome Using Whole-Exome Sequencing.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.829613

By:

Zhuang, Jianlong;
Chen, Chunnuan;
Chen, Yu'e;
Zeng, Shuhong;
Jiang, Yuying;
Wang, Yuanbai;
Chen, Xinying;
Xie, Yingjun;
Wang, Gaoxiong

Publication type:

Article

Association between red cell distribution width/serum albumin ratio and Parkinson's disease.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02707-z

By:

Li, Mimi;
Xu, Yingying;
Huang, Zhengping;
Ye, Lichao;
Chen, Chunnuan

Publication type:

Article

Case Report: Novel compound heterozygous variants in CHRNA1 gene leading to lethal multiple pterygium syndrome: A case report.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.964098

By:

Jianlong Zhuang;
Junyu Wang;
Qi Luo;
Shuhong Zeng;
Yu'e Chen;
Yuying Jiang;
Xinying Chen;
Yuanbai Wang;
Yingjun Xie;
Gaoxiong Wang;
Chunnuan Chen

Publication type:

Article

Case Report: Prenatal Whole-Exome Sequencing Identified a Novel Nonsense Mutation of the KCNH2 Gene in a Fetus With Familial 2q14.2 Duplication.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.924573

By:

Jianlong Zhuang;
Chunnuan Chen;
Yuanbai Wang;
Shuhong Zeng;
Yu'e Chen;
Yuying Jiang;
Yingjun Xie;
Gaoxiong Wang

Publication type:

Article

Fat mass and obesity–mediated N<sup>6</sup>-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury.

Published in:

Neural Regeneration Research, 2026, v. 21, n. 2, p. 730, doi. 10.4103/NRR.NRR-D-23-01854

By:

Chen, Xiangrong;
Lai, Jinqing;
Wu, Zhe;
Chen, Jianlong;
Yang, Baoya;
Chen, Chunnuan;
Ding, Chenyu

Publication type:

Article

First clinical and pedigree study of rare HBB: c.316–90 A > G variant in β-globin gene in Chinese population using third-generation sequencing.

Published in:

Annals of Hematology, 2025, v. 104, n. 1, p. 75, doi. 10.1007/s00277-024-06168-y

By:

Zhuang, Jianlong;
Huang, Nan;
Zheng, Yu;
Zhang, Na;
Chen, Chunnuan

Publication type:

Article

A study of familial MELAS: Evaluation of A3243G mutation, clinical phenotype, and magnetic resonance spectroscopy-monitored progression.

Published in:

Neurology India, 2012, v. 60, n. 1, p. 86, doi. 10.4103/0028-3886.93609

By:

Chunnuan Chen;
Nian Xiong;
Yuhui Wang;
Jing Xiong;
Jinsha Huang;
Zhentao Zhang;
Tao Wang

Publication type:

Article

Glucocerebrosidase L444P mutation confers genetic risk for Parkinson's disease in central China.

Published in:

Behavioral & Brain Functions, 2012, v. 8, n. 1, p. 57, doi. 10.1186/1744-9081-8-57

By:

Youpei Wang;
Ling Liu;
Jing Xiong;
Xiaowei Zhang;
Zhenzhen Chen;
Lan Yu;
Chunnuan Chen;
Jinsha Huang;
Zhentao Zhang;
Mohmed, Asrah A.;
Zhicheng Lin;
Nian Xiong;
Tao Wang

Publication type:

Article

Elevated high-sensitivity C-reactive protein levels are associated with intracranial arterial stenosis in elderly patients.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04208-2

By:

Li, Mimi;
Liu, Shufen;
Chen, Chunnuan

Publication type:

Article

Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models.

Published in:

Critical Reviews in Toxicology, 2012, v. 42, n. 7, p. 613, doi. 10.3109/10408444.2012.680431

By:

Xiong, Nian;
Long, Xi;
Xiong, Jing;
Jia, Min;
Chen, Chunnuan;
Huang, Jinsha;
Ghoorah, Devina;
Kong, Xiangquan;
Lin, Zhicheng;
Wang, Tao

Publication type:

Article

Prenatal diagnosis and molecular cytogenetic characterization of fetuses with central nervous system anomalies using chromosomal microarray analysis: a seven-year single-center retrospective study.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52831-9

By:

Zhuang, Jianlong;
Zhang, Na;
Chen, Yu'e;
Jiang, Yuying;
Chen, Xinying;
Chen, Wenli;
Chen, Chunnuan

Publication type:

Article

Case Report: Prenatal diagnosis of novel compound heterozygous variants in WDR35 gene causing short-rib thoracic dysplasia 7 with or without polydactyly.

Published in:

Frontiers in Pediatrics, 2025, p. 1, doi. 10.3389/fped.2024.1503455

By:

Zhuang, Jianlong;
Wang, Junyu;
Huang, Zhengping;
Chen, Yu'e;
Chen, Chunnuan

Publication type:

Article

Genetic Variants in GAPDH Confer Susceptibility to Sporadic Parkinson’s Disease in a Chinese Han Population.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135425

By:

Liu, Ling;
Xiong, Nian;
Zhang, Ping;
Chen, Chunnuan;
Huang, Jinsha;
Zhang, Guoxin;
Xu, Xiaoyun;
Shen, Yan;
Lin, Zhicheng;
Wang, Tao

Publication type:

Article

Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020677

By:

Nian Xiong;
Jing Xiong;
Khare, Ghanshyam;
Chunnuan Chen;
Jinsha Huang;
Ying Zhao;
Zhentao Zhang;
Xian Qiao;
Yuan Feng;
Reesaul, Harrish;
Yongxue Zhang;
Shenggang Sun;
Zhicheng Lin;
Tao Wang

Publication type:

Article

Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic Degeneration.

Published in:

Molecular Neurobiology, 2016, v. 53, n. 2, p. 995, doi. 10.1007/s12035-014-9057-2

By:

Xiong, Jing;
Zhang, Xiaowei;
Huang, Jinsha;
Chen, Chunnuan;
Chen, Zhenzhen;
Liu, Ling;
Zhang, Guoxin;
Yang, Jiaolong;
Zhang, Zhentao;
Zhang, Zhaohui;
Lin, Zhicheng;
Xiong, Nian;
Wang, Tao

Publication type:

Article

Molecular cytogenetic characterization of isolated recurrent 4q35.2 microduplication in Chinese population: a seven-year single-center retrospective study.

Published in:

BMC Pregnancy & Childbirth, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12884-024-06818-z

By:

Zhuang, Jianlong;
Wei, Qiulan;
Jiang, Yuying;
Zeng, Shuhong;
Lou, Haijuan;
Zhang, Na;
Chen, Chunnuan

Publication type:

Article

Molecular characterization of a rare TP63 variant associated with split-hand/split-foot malformation 4 and incomplete penetrance: disruption of the p63-Dlx signaling pathway.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11297-3

By:

Zhuang, Jianlong;
Li, Yanqing;
Chen, Yu'e;
Zhang, Hegan;
Liu, Shufen;
Hu, Manman;
Chen, Chunnuan

Publication type:

Article

Whole Exome Sequencing Revealing a Novel PBX1 Gene Variant in a Chinese Family Causing Recurrent Neonatal Death.

Published in:

Birth Defects Research, 2024, v. 116, n. 8, p. 1, doi. 10.1002/bdr2.2396

By:

Huang, Nan;
Zhang, Hegan;
Huang, Zhengping;
Wu, Xiaoxia;
Zhang, Na;
Jiang, Yuying;
Chen, Chunnuan;
Zhuang, Jianlong

Publication type:

Article

Initial clinical and molecular investigation of 20q13.33 microdeletion with 17q25.3/14q32.31q32.33 microduplication in Chinese pediatric patients.

Published in:

Molecular Genetics & Genomic Medicine, 2024, v. 12, n. 4, p. 1, doi. 10.1002/mgg3.2429

By:

Zhuang, Jianlong;
Zhang, Na;
Wang, Junyu;
Jiang, Yuying;
Zhang, Hegan;
Chen, Chunnuan

Publication type:

Article

Third‐generation sequencing identified two rare α‐chain variants leading to hemoglobin variants in Chinese population.

Published in:

Molecular Genetics & Genomic Medicine, 2024, v. 12, n. 1, p. 1, doi. 10.1002/mgg3.2365

By:

Zhuang, Jianlong;
Jiang, Yuying;
Chen, Yu'e;
Mao, Aiping;
Chen, Junwei;
Chen, Chunnuan

Publication type:

Article

Prenatal whole exome sequencing identified two rare compound heterozygous variants in EVC2 causing Ellis‐van Creveld syndrome.

Published in:

2023

By:

Zhuang, Jianlong;
Liu, Shufen;
Wang, Junyu;
Chen, Yu'e;
Zhang, Hegan;
Jiang, Yuying;
Wang, Gaoxiong;
Chen, Chunnuan

Publication type:

Case Study

Etiological identification of recurrent male fatality due to a novel NSDHL gene mutation using trio whole‐exome sequencing: A rare case report and literature review.

Published in:

Molecular Genetics & Genomic Medicine, 2023, v. 11, n. 3, p. 1, doi. 10.1002/mgg3.2121

By:

Zhuang, Jianlong;
Luo, Qi;
Xie, Meihua;
Chen, Yu'e;
Jiang, Yuying;
Zeng, Shuhong;
Wang, Yuanbai;
Xie, Yingjun;
Chen, Chunnuan

Publication type:

Article

Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulating microglia polarization through SIRT1-mediated deacetylation of the HMGB1/NF-κB pathway following experimental traumatic brain injury.

Published in:

2018

By:

Chen, Xiangrong;
Chen, Chunnuan;
Fan, Sining;
Wu, Shukai;
Yang, Fuxing;
Fang, Zhongning;
Fu, Huangde;
Li, Yasong

Publication type:

journal article

Application of the BACs-on-Beads assay for the prenatal diagnosis of chromosomal abnormalities in Quanzhou, China.

Published in:

BMC Pregnancy & Childbirth, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12884-021-03589-9

By:

Zhuang, Jianlong;
Chen, Chunnuan;
Jiang, Yuying;
Luo, Qi;
Zeng, Shuhong;
Lv, Chunling;
Wang, Yuanbai;
Fu, Wanyu

Publication type:

Article

Application of the BACs-on-Beads assay for the prenatal diagnosis of chromosomal abnormalities in Quanzhou, China.

Published in:

2021

By:

Zhuang, Jianlong;
Chen, Chunnuan;
Jiang, Yuying;
Luo, Qi;
Zeng, Shuhong;
Lv, Chunling;
Wang, Yuanbai;
Fu, Wanyu

Publication type:

journal article