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Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor.
- Published in:
- EMBO Molecular Medicine, 2020, v. 12, n. 2, p. N.PAG, doi. 10.15252/emmm.201809910
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- Publication type:
- Article
Retraction: Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.
- Published in:
- Carcinogenesis, 2019, v. 40, n. 2, p. e14, doi. 10.1093/carcin/bgz055
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- Publication type:
- Article
Retraction: Corrigendum: Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.
- Published in:
- Carcinogenesis, 2019, v. 40, n. 2, p. e15, doi. 10.1093/carcin/bgz057
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- Publication type:
- Article
Retraction: Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells.
- Published in:
- Carcinogenesis, 2019, v. 40, n. 2, p. e16, doi. 10.1093/carcin/bgz056
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- Publication type:
- Article
A 5′ AMP‐Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2018, v. 123, n. 1, p. 21, doi. 10.1111/bcpt.12976
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- Publication type:
- Article
Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis.
- Published in:
- 2017
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- Publication type:
- journal article
Preclinical Pharmacokinetics Study of R- and S-Enantiomers of the Histone Deacetylase Inhibitor, AR-42 (NSC 731438), in Rodents.
- Published in:
- AAPS Journal, 2016, v. 18, n. 3, p. 737, doi. 10.1208/s12248-016-9876-3
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- Article
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.
- Published in:
- 2015
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- Publication type:
- journal article
Trastuzumab resistance induces EMT to transform HER2<sup>+</sup> PTEN<sup>−</sup> to a triple negative breast cancer that requires unique treatment options.
- Published in:
- Scientific Reports, 2015, p. 15821, doi. 10.1038/srep15821
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- Publication type:
- Article
Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators.
- Published in:
- ChemMedChem, 2015, v. 10, n. 11, p. 1915, doi. 10.1002/cmdc.201500371
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- Publication type:
- Article
Caveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer.
- Published in:
- Scientific Reports, 2015, p. 10867, doi. 10.1038/srep10867
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- Publication type:
- Article
Extra-prostatic Transgene-associated Neoplastic Lesions in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.
- Published in:
- Toxicologic Pathology, 2015, v. 43, n. 2, p. 186, doi. 10.1177/0192623314531351
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- Publication type:
- Article
Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells.
- Published in:
- Carcinogenesis, 2014, v. 35, n. 10, p. 2203, doi. 10.1093/carcin/bgu124
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- Publication type:
- Article
Prospects on Strategies for Therapeutically Targeting Oncogenic Regulatory Factors by Small-Molecule Agents.
- Published in:
- Journal of Cellular Biochemistry, 2014, v. 115, n. 4, p. 611, doi. 10.1002/jcb.24704
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- Article
Novel Pharmacologic Targeting of Tight Junctions and Focal Adhesions in Prostate Cancer Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086238
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- Publication type:
- Article
Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.
- Published in:
- Carcinogenesis, 2013, v. 34, n. 12, p. 2694, doi. 10.1093/carcin/bgt251
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- Publication type:
- Article
Histone deacetylase inhibitor AR-42 enhances E7-specific CD8 T cell-mediated antitumor immunity induced by therapeutic HPV DNA vaccination.
- Published in:
- Journal of Molecular Medicine, 2013, v. 91, n. 10, p. 1221, doi. 10.1007/s00109-013-1054-9
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- Publication type:
- Article
Development of p21 activated kinase-targeted multikinase inhibitors that inhibit thyroid cancer cell migration.
- Published in:
- 2013
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- Publication type:
- journal article
Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067149
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- Publication type:
- Article
Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
- Published in:
- Prostate, 2012, v. 72, n. 16, p. 1767, doi. 10.1002/pros.22530
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- Publication type:
- Article
Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells.
- Published in:
- Breast Cancer Research & Treatment, 2012, v. 133, n. 2, p. 649, doi. 10.1007/s10549-012-2106-5
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- Publication type:
- Article
Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.
- Published in:
- Laryngoscope, 2012, v. 122, n. 1, p. 174, doi. 10.1002/lary.22392
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- Publication type:
- Article
A Review of the Existing Grading Schemes and a Proposal for a Modified Grading Scheme for Prostatic Lesions in TRAMP Mice.
- Published in:
- Toxicologic Pathology, 2012, v. 40, n. 1, p. 5, doi. 10.1177/0192623311425062
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- Publication type:
- Article
AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.
- Published in:
- Neuro-Oncology, 2011, v. 13, n. 9, p. 983, doi. 10.1093/neuonc/nor072
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- Publication type:
- Article
Development of a brain metastatic canine prostate cancer cell line.
- Published in:
- Prostate, 2011, v. 71, n. 12, p. 1251, doi. 10.1002/pros.21341
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- Publication type:
- Article
The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.
- Published in:
- International Journal of Cancer, 2011, v. 129, n. 1, p. 204, doi. 10.1002/ijc.25660
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- Publication type:
- Article
Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity.
- Published in:
- Aging Cell, 2011, v. 10, n. 3, p. 506, doi. 10.1111/j.1474-9726.2011.00688.x
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- Publication type:
- Article
OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway.
- Published in:
- British Journal of Haematology, 2011, v. 153, n. 5, p. 623, doi. 10.1111/j.1365-2141.2010.08443.x
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- Publication type:
- Article
{alpha}-Tocopheryl succinate and derivatives mediate the transcriptional repression of androgen receptor in prostate cancer cells by targeting the PP2A-JNK-Sp1-signaling axis.
- Published in:
- Carcinogenesis, 2009, v. 30, n. 7, p. 1125, doi. 10.1093/carcin/bgp112
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- Publication type:
- Article
OSU03012 activates Erk1/2 and Cdks leading to the accumulation of cells in the S-phase and apoptosis.
- Published in:
- International Journal of Cancer, 2008, v. 123, n. 12, p. 2923, doi. 10.1002/ijc.23896
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- Publication type:
- Article
Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21.
- Published in:
- International Journal of Cancer, 2008, v. 123, n. 12, p. 2931, doi. 10.1002/ijc.23895
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- Publication type:
- Article
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.
- Published in:
- 2007
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- Publication type:
- journal article
Targeting histone deacetylase in cancer therapy.
- Published in:
- Medicinal Research Reviews, 2006, v. 26, n. 4, p. 397, doi. 10.1002/med.20056
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- Publication type:
- Article
Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone.
- Published in:
- International Journal of Cancer, 2006, v. 118, n. 10, p. 2390, doi. 10.1002/ijc.21799
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- Publication type:
- Article
Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9.
- Published in:
- International Journal of Cancer, 2005, v. 113, n. 5, p. 803, doi. 10.1002/ijc.20639
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- Publication type:
- Article
Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.
- Published in:
- 2002
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- Publication type:
- journal article
Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells.
- Published in:
- 2002
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- Publication type:
- journal article
Enzymatic catalysis in cosolvent modified pressurized organic solvents.
- Published in:
- Biotechnology & Bioengineering, 1999, v. 65, n. 3, p. 258, doi. 10.1002/(SICI)1097-0290(19991105)65:3<258::AID-BIT2>3.0.CO;2-A
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- Publication type:
- Article
CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase.
- Published in:
- European Journal of Immunology, 1998, v. 28, n. 10, p. 3003, doi. 10.1002/(SICI)1521-4141(199810)28:10<3003::AID-IMMU3003>3.0.CO;2-W
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- Publication type:
- Article
Preparation of enantiomerically-active deuterium-labelled ibuprofen.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1990, v. 28, n. 9, p. 1017, doi. 10.1002/jlcr.2580280905
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- Publication type:
- Article
General Aspects and Optimization of Enantioselective Biocatalysis in Organic Solvents: The Use of Lipases [New Synthetic Methods (76)].
- Published in:
- Angewandte Chemie International Edition, 1989, v. 28, n. 6, p. 695, doi. 10.1002/anie.198906951
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- Publication type:
- Article
Biochemical Asymmetric Catalysis<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1986, v. 471, n. 1, p. 239, doi. 10.1111/j.1749-6632.1986.tb48040.x
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- Publication type:
- Article
Enantioselective Reductions of β-keto-Esters by Bakers' Yeast.
- Published in:
- Annals of the New York Academy of Sciences, 1984, v. 434, n. 1, p. 186, doi. 10.1111/j.1749-6632.1984.tb29826.x
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- Publication type:
- Article
Microbial Asymmetric Catalysis-Enantioselective Reduction of Ketones [New Synthetic Methods (45)].
- Published in:
- Angewandte Chemie International Edition, 1984, v. 23, n. 8, p. 570, doi. 10.1002/anie.198405701
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- Publication type:
- Article