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Animal Models Relevant for Geroscience: Current Trends and Future Perspectives in Biomarkers, and Measures of Biological Aging.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 9, p. 1, doi. 10.1093/gerona/glae135
By:
- Bartolomucci, Alessandro;
- Kane, Alice E;
- Gaydosh, Lauren;
- Razzoli, Maria;
- McCoy, Brianah M;
- Ehninger, Dan;
- Chen, Brian H;
- Howlett, Susan E;
- Snyder-Mackler, Noah
Publication type:
Article
Association of Epigenetic Age Acceleration With Incident Mild Cognitive Impairment and Dementia Among Older Women.
Published in:
2022
By:
- Shadyab, Aladdin H;
- McEvoy, Linda K;
- Horvath, Steve;
- Whitsel, Eric A;
- Rapp, Stephen R;
- Espeland, Mark A;
- Resnick, Susan M;
- Manson, JoAnn E;
- Chen, Jiu-Chiuan;
- Chen, Brian H;
- Li, Wenjun;
- Hayden, Kathleen M;
- Bao, Wei;
- Kusters, Cynthia D J;
- LaCroix, Andrea Z
Publication type:
journal article
Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.
Published in:
2019
By:
- Marioni, Riccardo E;
- Suderman, Matthew;
- Chen, Brian H;
- Horvath, Steve;
- Bandinelli, Stefania;
- Morris, Tiffany;
- Beck, Stephan;
- Ferrucci, Luigi;
- Pedersen, Nancy L;
- Relton, Caroline L;
- Deary, Ian J;
- Hägg, Sara
Publication type:
journal article
Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction.
Published in:
Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0588-7
By:
- Ward-Caviness, Cavin K.;
- Agha, Golareh;
- Chen, Brian H.;
- Pfeiffer, Liliane;
- Wilson, Rory;
- Wolf, Petra;
- Gieger, Christian;
- Schwartz, Joel;
- Vokonas, Pantel S.;
- Hou, Lifang;
- Just, Allan C.;
- Bandinelli, Stefania;
- Hernandez, Dena G.;
- Singleton, Andrew B.;
- Prokisch, Holger;
- Meitinger, Thomas;
- Kastenmüller, Gabi;
- Ferrucci, Luigi;
- Baccarelli, Andrea A.;
- Waldenberger, Melanie
Publication type:
Article
Association of blood‐based epigenetic age acceleration with cognitive impairment and brain outcomes by cardiovascular disease among women.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051774
By:
- Shadyab, Aladdin H.;
- McEvoy, Linda K.;
- Horvath, Steve;
- Whitsel, Eric A.;
- Rapp, Stephen R.;
- Espeland, Mark A.;
- Resnick, Susan M.;
- Chen, Jiu‐Chiuan;
- Chen, Brian H.;
- Li, Wenjun;
- Hayden, Kathleen M.;
- Manson, JoAnn E.;
- Bao, Wei;
- Kusters, Cynthia D.J.;
- LaCroix, Andrea Z.
Publication type:
Article
Identification of common genetic variants controlling transcript isoform variation in human whole blood.
Published in:
Nature Genetics, 2015, v. 47, n. 4, p. 345, doi. 10.1038/ng.3220
By:
- Zhang, Xiaoling;
- Chen, Brian H;
- Huan, Tianxiao;
- Johnson, Andrew D;
- Levy, Daniel;
- Joehanes, Roby;
- Ying, Saixia;
- Munson, Peter J;
- O'Donnell, Christopher J
Publication type:
Article
Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes.
Published in:
2016
By:
- Yin, Xiaoyan;
- Subramanian, Subha;
- Willinger, Christine M;
- Chen, George;
- Juhasz, Peter;
- Courchesne, Paul;
- Chen, Brian H;
- Li, Xiaohang;
- Hwang, Shih-Jen;
- Fox, Caroline S;
- O'Donnell, Christopher J;
- Muntendam, Pieter;
- Fuster, Valentin;
- Bobeldijk-Pastorova, Ivana;
- Sookoian, Silvia C;
- Pirola, Carlos J;
- Gordon, Neal;
- Adourian, Aram;
- Larson, Martin G;
- Levy, Daniel
Publication type:
journal article
mLiftOver: harmonizing data across Infinium DNA methylation platforms.
Published in:
Bioinformatics, 2024, v. 40, n. 7, p. 1, doi. 10.1093/bioinformatics/btae423
By:
- Chen, Brian H;
- Zhou, Wanding
Publication type:
Article
Simplified Assay for Epigenetic Age Estimation in Whole Blood of Adults.
Published in:
Frontiers in Genetics, 2016, p. 1, doi. 10.3389/fgene.2016.00126
By:
- Vidal-Bralo, Laura;
- Lopez-Golan, Yolanda;
- Gonzalez, Antonio;
- Zhavoronkov, Alex;
- Chen, Brian H.
Publication type:
Article
The 2020 FASEB virtual Catalyst Conference on Integrative Approach for Complex Diseases Prevention and Management and Beyond, December 16, 2020.
Published in:
FASEB Journal, 2021, v. 35, n. 7, p. 1, doi. 10.1096/fj.202100317
By:
- Chan, Kei Hang Katie;
- Hsu, Yi‐Hsiang;
- Yang, Xia;
- Goto, Atsushi;
- Chen, Brian H.
Publication type:
Article
Integrative network analysis reveals molecular mechanisms of blood pressure regulation.
Published in:
Molecular Systems Biology, 2015, v. 11, n. 4, p. n/a, doi. 10.15252/msb.20145399
By:
- Huan, Tianxiao;
- Meng, Qingying;
- Saleh, Mohamed A;
- Norlander, Allison E;
- Joehanes, Roby;
- Zhu, Jun;
- Chen, Brian H;
- Zhang, Bin;
- Johnson, Andrew D;
- Ying, Saixia;
- Courchesne, Paul;
- Raghavachari, Nalini;
- Wang, Richard;
- Liu, Poching;
- O'Donnell, Christopher J;
- Vasan, Ramachandran;
- Munson, Peter J;
- Madhur, Meena S;
- Harrison, David G;
- Yang, Xia
Publication type:
Article
Age, Body Mass, Usage of Exogenous Estrogen, and Lifestyle Factors in Relation to Circulating Sex Hormone--Binding Globulin Concentrations in Postmenopausal Women.
Published in:
Clinical Chemistry, 2014, v. 60, n. 1, p. 174, doi. 10.1373/clinchem.2013.207217
By:
- Atsushi Goto;
- Chen, Brian H.;
- Yiqing Song;
- Cauley, Jane;
- Cummings, Steven R.;
- Farhat, Ghada N.;
- Gunter, Marc;
- Van Horn, Linda;
- Howard, Barbara V.;
- Jackson, Rebecca;
- Lee, Jennifer;
- Rexrode, Kathryn M.;
- Simin Liu
Publication type:
Article
Sex Hormone--Binding Globulin and Risk of Clinical Diabetes in American Black, Hispanic, and Asian/Pacific Islander Postmenopausal Women.
Published in:
Clinical Chemistry, 2012, v. 58, n. 10, p. 1457, doi. 10.1373/clinchem.2012.193086
By:
- Chen, Brian H.;
- Brennan, Kathleen;
- Goto, Atsushi;
- Song, Yiqing;
- Aziz, Najib;
- You, Nai-chieh Y.;
- Wellons, Melissa F.;
- Manson, JoAnn E.;
- White, Donna L.;
- Butch, Anthony W.;
- Liu, Simin
Publication type:
Article
Genome-wide identification of microRNA expression quantitative trait loci.
Published in:
Nature Communications, 2015, v. 6, n. 3, p. 6601, doi. 10.1038/ncomms7601
By:
- Huan, Tianxiao;
- Rong, Jian;
- Liu, Chunyu;
- Zhang, Xiaoling;
- Tanriverdi, Kahraman;
- Joehanes, Roby;
- Chen, Brian H.;
- Murabito, Joanne M.;
- Yao, Chen;
- Courchesne, Paul;
- Munson, Peter J.;
- O'Donnell, Christopher J.;
- Cox, Nancy;
- Johnson, Andrew D.;
- Larson, Martin G.;
- Levy, Daniel;
- Freedman, Jane E.
Publication type:
Article
DNA methylation age of blood predicts all-cause mortality in later life.
Published in:
Genome Biology, 2015, v. 16, n. 1, p. 345, doi. 10.1186/s13059-015-0584-6
By:
- Marioni, Riccardo E.;
- Shah, Sonia;
- McRae, Allan F.;
- Chen, Brian H.;
- Colicino, Elena;
- Harris, Sarah E.;
- Gibson, Jude;
- Henders, Anjali K.;
- Redmond, Paul;
- Cox, Simon R.;
- Pattie, Alison;
- Corley, Janie;
- Murphy, Lee;
- Martin, Nicholas G.;
- Montgomery, Grant W.;
- Feinberg, Andrew P.;
- Fallin, M. Daniele;
- Multhaup, Michael L.;
- Jaffe, Andrew E.;
- Joehanes, Roby
Publication type:
Article
Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0722-1
By:
- Tajuddin, Salman M.;
- Hernandez, Dena G.;
- Chen, Brian H.;
- Noren Hooten, Nicole;
- Mode, Nicolle A.;
- Nalls, Mike A.;
- Singleton, Andrew B.;
- Ejiogu, Ngozi;
- Chitrala, Kumaraswamy Naidu;
- Zonderman, Alan B.;
- Evans, Michele K.
Publication type:
Article
Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African American, Hispanic American, and European American postmenopausal women in the US.
Published in:
Journal of Diabetes, 2018, v. 10, n. 6, p. 524, doi. 10.1111/1753-0407.12648
By:
- Goto, Atsushi;
- Chen, Brian H.;
- Chan, Kei‐hang K.;
- Lee, Cathy;
- Nelson, Sarah C.;
- Crenshaw, Andrew;
- Bookman, Ebony;
- Margolis, Karen L.;
- Sale, Michèle M.;
- The MEta‐analysis of type 2 DIabetes in African Americans (MEDIA) Consortium;
- Ng, Maggie C. Y.;
- Reiner, Alexander P.;
- Liu, Simin
Publication type:
Article
Relationships of sex hormone levels with leukocyte telomere length in Black, Hispanic, and Asian/Pacific Islander postmenopausal women.
Published in:
Journal of Diabetes, 2018, v. 10, n. 6, p. 502, doi. 10.1111/1753-0407.12577
By:
- Song, Yan;
- Cho, Michele;
- Brennan, Kathleen M.;
- Chen, Brian H.;
- Song, Yiqing;
- Manson, JoAnn E.;
- Hevener, Andrea L.;
- You, Nai‐Chieh Y.;
- Butch, Anthony W.;
- Liu, Simin
Publication type:
Article
Minimum standards for evaluating machine-learned models of high-dimensional data.
Published in:
Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.901841
By:
- Chen, Brian H.
Publication type:
Article
GWAS of epigenetic aging rates in blood reveals a critical role for TERT.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02697-5
By:
- Lu, Ake T.;
- Luting Xue;
- Salfati, Elias L.;
- Chen, Brian H.;
- Ferrucci, Luigi;
- Levy, Daniel;
- Joehanes, Roby;
- Murabito, Joanne M.;
- Kiel, Douglas P.;
- Pei-Chien Tsai;
- Yet, Idil;
- Bell, Jordana T.;
- Mangino, Massimo;
- Toshiko Tanaka;
- McRae, Allan F.;
- Marioni, Riccardo E.;
- Visscher, Peter M.;
- Wray, Naomi R.;
- Deary, Ian J.;
- Levine, Morgan E.
Publication type:
Article
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Published in:
Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-1119-5
By:
- Ligthart, Symen;
- Marzi, Carola;
- Aslibekyan, Stella;
- Mendelson, Michael M.;
- Conneely, Karen N.;
- Toshiko Tanaka;
- Colicino, Elena;
- Waite, Lindsay L.;
- Joehanes, Roby;
- Weihua Guan;
- Brody, Jennifer A.;
- Elks, Cathy;
- Marioni, Riccardo;
- Min A. Jhun;
- Agha, Golareh;
- Bressler, Jan;
- Ward-Caviness, Cavin K.;
- Chen, Brian H.;
- Tianxiao Huan;
- Bakulski, Kelly
Publication type:
Article
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension.
Published in:
PLoS Genetics, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pgen.1005035
By:
- Huan, Tianxiao;
- Esko, Tõnu;
- Peters, Marjolein J.;
- Pilling, Luke C.;
- Schramm, Katharina;
- Schurmann, Claudia;
- Chen, Brian H.;
- Liu, Chunyu;
- Joehanes, Roby;
- Johnson, Andrew D.;
- Yao, Chen;
- Ying, Sai-xia;
- Courchesne, Paul;
- Milani, Lili;
- Raghavachari, Nalini;
- Wang, Richard;
- Liu, Poching;
- Reinmaa, Eva;
- Dehghan, Abbas;
- Hofman, Albert
Publication type:
Article
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes.
Published in:
PLoS Genetics, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pgen.1004517
By:
- Ng, Maggie C. Y.;
- Shriner, Daniel;
- Chen, Brian H.;
- Li, Jiang;
- Chen, Wei-Min;
- Guo, Xiuqing;
- Liu, Jiankang;
- Bielinski, Suzette J.;
- Yanek, Lisa R.;
- Nalls, Michael A.;
- Comeau, Mary E.;
- Rasmussen-Torvik, Laura J.;
- Jensen, Richard A.;
- Evans, Daniel S.;
- Sun, Yan V.;
- An, Ping;
- Patel, Sanjay R.;
- Lu, Yingchang;
- Long, Jirong;
- Armstrong, Loren L.
Publication type:
Article
Circulating Levels of Resistin and Risk of Type 2 Diabetes in Men and Women: Results From Two Prospective Cohorts.
Published in:
Diabetes Care, 2009, v. 32, n. 2, p. 329, doi. 10.2337/dc08-1625
By:
- Chen, Brian H.;
- Yiqing Song;
- Ding, Eric L.;
- Roberts, Christian K.;
- Manson, Joann E.;
- Rifai, Nader;
- Buring, Julie E.;
- Gaziano, J. Michael;
- Liu, Simin
Publication type:
Article
Age‐associated microRNA expression in human peripheral blood is associated with all‐cause mortality and age‐related traits.
Published in:
Aging Cell, 2018, v. 17, n. 1, p. 1, doi. 10.1111/acel.12687
By:
- Huan, Tianxiao;
- Chen, George;
- Liu, Chunyu;
- Bhattacharya, Anindya;
- Rong, Jian;
- Chen, Brian H.;
- Seshadri, Sudha;
- Tanriverdi, Kahraman;
- Freedman, Jane E.;
- Larson, Martin G.;
- Murabito, Joanne M.;
- Levy, Daniel
Publication type:
Article
Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations.
Published in:
2016
By:
- Chen, Brian H;
- Hivert, Marie-France;
- Peters, Marjolein J;
- Pilling, Luke C;
- Hogan, John D;
- Pham, Lisa M;
- Harries, Lorna W;
- Fox, Caroline S;
- Bandinelli, Stefania;
- Dehghan, Abbas;
- Hernandez, Dena G;
- Hofman, Albert;
- Hong, Jaeyoung;
- Joehanes, Roby;
- Johnson, Andrew D;
- Munson, Peter J;
- Rybin, Denis V;
- Singleton, Andrew B;
- Uitterlinden, André G;
- Ying, Saixia
Publication type:
journal article
Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations.
Published in:
Diabetes, 2016, v. 65, n. 12, p. 3974, doi. 10.2337/db16-0470
By:
- Chen, Brian H.;
- Hivert, Marie-France;
- Peters, Marjolein J.;
- Pilling, Luke C.;
- Hogan, John D.;
- Pham, Lisa M.;
- Harries, Lorna W.;
- Fox, Caroline S.;
- Bandinelli, Stefania;
- Dehghan, Abbas;
- Hernandez, Dena G.;
- Hofman, Albert;
- Jaeyoung Hong;
- Joehanes, Roby;
- Johnson, Andrew D.;
- Munson, Peter J.;
- Rybin, Denis V.;
- Singleton, Andrew B.;
- Uitterlinden, André G.;
- Saixia Ying
Publication type:
Article
A Prospective Study of Leukocyte Telomere Length and Risk of Type 2 Diabetes in Postmenopausal Women.
Published in:
Diabetes, 2012, v. 61, n. 11, p. 2998, doi. 10.2337/db12-0241
By:
- You, Nai-chieh Y.;
- Chen, Brian H.;
- Yiqing Song;
- XuYang Lu;
- Yilin Chen;
- Manson, JoAnn E.;
- Mo Kang;
- Howard, Barbara V.;
- Margolis, Karen L.;
- Curb, J. David;
- Phillips, Lawrence S.;
- Stefanick, Marcia L.;
- Tinker, Lesley F.;
- Simin Liu
Publication type:
Article
Coffee and Caffeine Consumption in Relation to Sex Hormone-Binding Globulin and Risk of Type 2 Diabetes in Postmenopausal Women.
Published in:
Diabetes, 2011, v. 60, n. 1, p. 269, doi. 10.2337/db10-1193
By:
- Goto, Atsushi;
- Song, Yiqing;
- Chen, Brian H.;
- Manson, JoAnn E.;
- Buring, Julie E.;
- Liu, Simin
Publication type:
Article

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