Works by Chazenbalk, Gregorio D.

Results: 24

An Evolutionary Model for the Ancient Origins of Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 19, p. 6120, doi. 10.3390/jcm12196120

By:

Dumesic, Daniel A.;
Abbott, David H.;
Chazenbalk, Gregorio D.

Publication type:

Article

The Subcutaneous Adipose Microenvironment as a Determinant of Body Fat Development in Polycystic Ovary Syndrome.

Published in:

Journal of the Endocrine Society, 2024, v. 8, n. 11, p. 1, doi. 10.1210/jendso/bvae162

By:

Dumesic, Daniel A;
Rasouli, Melody A;
Katz, Jessica D;
Lu, Gwyneth G;
Dharanipragada, Devyani;
Turcu, Adina F;
Grogan, Tristan R;
Flores, Kimberly E;
Magyar, Clara E;
Abbott, David H;
Chazenbalk, Gregorio D

Publication type:

Article

Interplay of Cortisol, Testosterone, and Abdominal Fat Mass in Normal-weight Women With Polycystic Ovary Syndrome.

Published in:

Journal of the Endocrine Society, 2023, v. 7, n. 8, p. 1, doi. 10.1210/jendso/bvad079

By:

Dumesic, Daniel A;
Turcu, Adina F;
Liu, Haiping;
Grogan, Tristan R;
Abbott, David H;
Lu, Gwyneth;
Dharanipragada, Devyani;
Chazenbalk, Gregorio D

Publication type:

Article

Serum Testosterone to Androstenedione Ratio Predicts Metabolic Health in Normal-Weight Polycystic Ovary Syndrome Women.

Published in:

Journal of the Endocrine Society, 2021, v. 5, n. 11, p. 1, doi. 10.1210/jendso/bvab158

By:

Dumesic, Daniel A;
Tulberg, Ayli;
McNamara, Megan;
Grogan, Tristan R;
Abbott, David H;
Naik, Rajanigandha;
Lu, Gwyneth;
Chazenbalk, Gregorio D

Publication type:

Article

Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues—A Paradigm Shift in Tissue Regeneration and Evolution.

Published in:

Stem Cells International, 2016, p. 1, doi. 10.1155/2016/1463258

By:

Simerman, Ariel A.;
Phan, Julia D.;
Dumesic, Daniel A.;
Chazenbalk, Gregorio D.

Publication type:

Article

Affinity-Enrichment of Thyrotropin Receptor Autoantibodies from Graves’ Patients and Normal Individuals Provides Insight into Their Properties and Possible Origin from Natural Antibodies.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 9, p. 4734, doi. 10.1210/jc.2003-032068

By:

LATROFA, FRANCESCO;
CHAZENBALK, GREGORIO D.;
PICHURIN, PAVEL;
CHUN-RONG CHEN;
MCLACHLAN, SANDRA M.;
RAPOPORT, BASIL

Publication type:

Article

Thyroid Stimulation Does Not Require Antibodies with Identical Epitopes But Does Involve Recognition of a Critical Conformation at the N Terminus of the Thyrotropin Receptor A-Subunit.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 4, p. 1788, doi. 10.1210/jc.2003-031554

By:

CHAZENBALK, GREGORIO D.;
LATROFA, FRANCESCO;
MCLACHLAN, SANDRA M.;
RAPOPORT, BASIL

Publication type:

Article

A Prion-Like Shift between Two Conformational Forms of a Recombinant Thyrotropin Receptor A-Subunit Module: Purification and Stabilization Using Chemical Chaperones of the Form Reactive with Graves’ Autoantibodies.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 3, p. 1287, doi. 10.1210/jcem.86.3.7363

By:

CHAZENBALK, GREGORIO D.;
MCLACHLAN, SANDRA M.;
PICHURIN, PAVEL;
XIN-MIN YAN;
RAPOPORT, BASIL

Publication type:

Article

A Mouse Monoclonal Antibody to a Thyrotropin Receptor Ectodomain Variant Provides Insight into the Exquisite Antigenic Conformational Requirement, Epitopes and in Vivo Concentration of Human Autoantibodies.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 2, p. 702, doi. 10.1210/jcem.84.2.5481

By:

CHAZENBALK, GREGORIO D.;
YAN WANG;
JIN GUO;
HUTCHISON, J. SCOTT;
SEGAL, DEAN;
JAUME, JUAN CARLOS;
MCLACHLAN, SANDRA M.;
RAPOPORT, BASIL

Publication type:

Article

The Human Thyrotropin (TSH) Receptor in a TSH Binding Inhibition Assay for TSH Receptor Autoantibodies*.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 7, p. 2129, doi. 10.1210/jcem.82.7.4092

By:

KAKINUMA, AYUMU;
CHAZENBALK, GREGORIO D.;
JAUME, JUAN CARLOS;
RAPOPORT, BASIL;
McLACHLAN, SANDRA M.

Publication type:

Article

Thyrotropin Receptor Autoantibodies in Serum Are Present at Much Lower Levels Than Thyroid Peroxidase Autoantibodies: Analysis by Flow Cytometry.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 2, p. 500, doi. 10.1210/jcem.82.2.3740

By:

JAUME, JUAN CARLOS;
KAKINUMA, AYUMU;
CHAZENBALK, GREGORIO D.;
RAPOPORT, BASIL;
MCLACHLAN, SANDRA M.

Publication type:

Article

Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2016, p. 4178, doi. 10.1210/jc.2016-2586

By:

Dumesic, Daniel A.;
Akopians, Alin L.;
Madrigal, Vanessa K.;
Ramirez, Emmanuel;
Margolis, Daniel J.;
Sarma, Manoj K.;
Thomas, Albert M.;
Grogan, Tristan R.;
Haykal, Rasha;
Schooler, Tery A.;
Okeya, Bette L.;
Abbott, David H.;
Chazenbalk, Gregorio D.

Publication type:

Article

Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women.

Published in:

2016

By:

Dumesic, Daniel A;
Akopians, Alin L;
Madrigal, Vanessa K;
Ramirez, Emmanuel;
Margolis, Daniel J;
Sarma, Manoj K;
Thomas, Albert M;
Grogan, Tristan R;
Haykal, Rasha;
Schooler, Tery A;
Okeya, Bette L;
Abbott, David H;
Chazenbalk, Gregorio D

Publication type:

journal article

Cumulus Cell Mitochondrial Resistance to Stress In Vitro Predicts Oocyte Development During Assisted Reproduction.

Published in:

2016

By:

Dumesic, Daniel A;
Guedikian, Annie A;
Madrigal, Vanessa K;
Phan, Julia D;
Hill, David L;
Alvarez, Juan P;
Chazenbalk, Gregorio D

Publication type:

journal article

21-Hydroxylase-derived steroids in follicles of nonobese women undergoing ovarian stimulation for in vitro fertilization (IVF) positively correlate with lipid content of luteinized granulosa cells (LGCs) as a source of cholesterol for steroid synthesis.

Published in:

2014

By:

Amin, Marli;
Simerman, Ariel;
Cho, Michele;
Singh, Prapti;
Briton-Jones, Christine;
Hill, David;
Grogan, Tristan;
Elashoff, David;
Clarke, Nigel J;
Chazenbalk, Gregorio D;
Dumesic, Daniel A

Publication type:

journal article

Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation.

Published in:

2022

By:

Dumesic, Daniel A.;
Padmanabhan, Vasantha;
Chazenbalk, Gregorio D.;
Abbott, David H.

Publication type:

Literature Review

Pluripotent nontumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year retrospective.

Published in:

Stem Cell Research & Therapy, 2017, v. 8, p. 1, doi. 10.1186/s13287-017-0674-3

By:

Fisch, Samantha C.;
Gimeno, María L.;
Phan, Julia D.;
Simerman, Ariel A.;
Dumesic, Daniel A.;
Perone, Marcelo J.;
Chazenbalk, Gregorio D.

Publication type:

Article

Loss of anti-Müllerian hormone (AMH) immunoactivity due to a homozygous AMH gene variant rs10417628 in a woman with classical polycystic ovary syndrome (PCOS).

Published in:

2020

By:

Hoyos, Luis R;
Visser, Jenny A;
McLuskey, Anke;
Chazenbalk, Gregorio D;
Grogan, Tristan R;
Dumesic, Daniel A

Publication type:

journal article

Pluripotent muse cells derived from human adipose tissue: a new perspective on regenerative medicine and cell therapy.

Published in:

Clinical & Translational Medicine, 2014, v. 3, n. 1, p. 1, doi. 10.1186/2001-1326-3-12

By:

Simerman, Ariel A;
Dumesic, Daniel A;
Chazenbalk, Gregorio D

Publication type:

Article

Evidence That the Thyrotropin Receptor Protease is Membrane-Associated and is Not Within Lipid Rafts.

Published in:

Thyroid, 2004, v. 14, n. 10, p. 801

By:

Francesco Latrofa;
Gregorio D. Chazenbalk;
Sandra M. McLachlan;
Basil Rapoport

Publication type:

Article

Reassessment of the Location of the Thyrotropin Receptor 50 Amino Acid "Insertion" Provides Evidence in Favor of a Second Downstream Cleavage Site.

Published in:

Thyroid, 2001, v. 11, n. 2, p. 111, doi. 10.1089/105072501300042721

By:

Tanaka, Kunihiko;
Chazenbalk, Gregorio D.;
Rapoport, Basil;
McLachlan, Sandra M.

Publication type:

Article

A Direct Binding Assay for Thyrotropin Receptor Autoantibodies.

Published in:

Thyroid, 1999, v. 9, n. 11, p. 1057, doi. 10.1089/thy.1999.9.1057

By:

CHAZENBALK, GREGORIO D.;
PICHURIN, PAVEL;
MCLACHLAN, SANDRA M.;
RAPOPORT, BASIL

Publication type:

Article

Adipose Insulin Resistance in Normal-Weight Women With Polycystic Ovary Syndrome.

Published in:

2019

By:

Dumesic, Daniel A;
Phan, Julia D;
Leung, Karen L;
Grogan, Tristan R;
Ding, Xiangmiang;
Li, Xinmin;
Hoyos, Luis R;
Abbott, David H;
Chazenbalk, Gregorio D

Publication type:

journal article

Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal-weight polycystic ovary syndrome (PCOS) women during adipogenesis: evidence of cellular programming

Published in:

Clinical Epigenetics, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13148-020-00970-x

By:

Leung, Karen L.;
Sanchita, Smriti;
Pham, Catherine T.;
Davis, Brett A.;
Okhovat, Mariam;
Ding, Xiangming;
Dumesic, Phillip;
Grogan, Tristan R.;
Williams, Kevin J.;
Morselli, Marco;
Ma, Feiyang;
Carbone, Lucia;
Li, Xinmin;
Pellegrini, Matteo;
Dumesic, Daniel A.;
Chazenbalk, Gregorio D.

Publication type:

Article