Works by Chapple, J. Paul

Results: 31

P2-151: A novel RNA affinity purification procedure to identify regulators of tau mRNA localisation

Published in:

2008

By:

Anthony, Karen;
Chapple, J. Paul;
Gallo, Jean-Marc

Publication type:

Abstract

Biophysical Studies of a Rhinovirus: Ultracentrifugation and Electron Microscopy.

Published in:

Nature, 1966, v. 209, n. 5025, p. 790, doi. 10.1038/209790a0

By:

CHAPPLE, PAUL J.;
HARRIS, W. J.

Publication type:

Article

Myxomatosis and the Rabbit Flea.

Published in:

Nature, 1965, v. 207, n. 4995, p. 388, doi. 10.1038/207388a0

By:

CHAPPLE, PAUL J.;
LEWIS, N. D.

Publication type:

Article

Electron Microscopy of Myxoma Virus.

Published in:

Nature, 1963, v. 199, n. 4889, p. 199, doi. 10.1038/199199a0

By:

CHAPPLE, PAUL J.;
WESTWOOD, J. C. N.

Publication type:

Article

Electrophoresis of Colicines in Agar Gel.

Published in:

Nature, 1962, v. 195, n. 4848, p. 1325, doi. 10.1038/1951325a0

By:

CHAPPLE, PAUL J.

Publication type:

Article

Modelling autosomal dominant optic atrophy associated with OPA1 variants in iPSC-derived retinal ganglion cells.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 20, p. 3478, doi. 10.1093/hmg/ddac128

By:

Sladen, Paul E;
Jovanovic, Katarina;
Guarascio, Rosellina;
Ottaviani, Daniele;
Salsbury, Grace;
Novoselova, Tatiana;
Chapple, J Paul;
Yu-Wai-Man, Patrick;
Cheetham, Michael E

Publication type:

Article

Corrigendum to: The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 19, p. 3338, doi. 10.1093/hmg/ddaa190

By:

Athanasiou, Dimitra;
Bevilacqua, Dalila;
Aguila, Monica;
McCulley, Caroline;
Kanuga, Naheed;
Takao Iwawaki;
Chapple, J. Paul;
Cheetham, Michael E.

Publication type:

Article

Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β.

Published in:

Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0891-z

By:

Thompson, Clare L.;
Patel, Riana;
Kelly, Terri-Ann N.;
Wann, Angus K. T.;
Hung, Clark T.;
Paul Chapple, J.;
Knight, Martin M.

Publication type:

Article

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.

Published in:

Nature Genetics, 2005, v. 37, n. 10, p. 1135, doi. 10.1038/ng1644

By:

Ross, Alison J.;
May-Simera, Helen;
Eichers, Erica R.;
Kai, Masatake;
Hill, Josephine;
Jagger, Daniel J.;
Leitch, Carmen C.;
Chapple, J. Paul;
Munro, Peter M.;
Fisher, Shannon;
Tan, Perciliz L.;
Phillips, Helen M.;
Leroux, Michel R.;
Henderson, Deborah J.;
Murdoch, Jennifer N.;
Copp, Andrew J.;
Eliot, Marie-Madeleine;
Lupski, James R.;
Kemp, David T.;
Dollfus, Hélène

Publication type:

Article

Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2.

Published in:

Nature Genetics, 2005, v. 37, n. 2, p. 166, doi. 10.1038/ng1501

By:

Metherell, Louise A;
Chapple, J Paul;
Cooray, Sadani;
David, Alessia;
Becker, Christian;
Rüschendorf, Franz;
Naville, Danielle;
Begeot, Martine;
Khoo, Bernard;
Nürnberg, Peter;
Huebner, Angela;
Cheetham, Michael E;
Clark, Adrian J L

Publication type:

Article

Primary cilia: a link between hormone signalling and endocrine-related cancers?

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 5, p. 1227, doi. 10.1042/BST20160149

By:

O'Toole, Samuel M.;
Chapple, J. Paul

Publication type:

Article

Optical coherence tomography in autosomal recessive spastic ataxia of Charlevoix-Saguenay.

Published in:

2018

By:

Parkinson, Michael H;
Bartmann, Ana P;
Clayton, Lisa M S;
Nethisinghe, Suran;
Pfundt, Rolph;
Chapple, J Paul;
Reilly, Mary M;
Manji, Hadi;
Wood, Nicholas J;
Bremner, Fion;
Giunti, Paola

Publication type:

journal article

Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families.

Published in:

Human Mutation, 2010, v. 31, n. 8, p. 950, doi. 10.1002/humu.21292

By:

Igreja, Susana;
Chahal, Harvinder S.;
King, Peter;
Bolger, Graeme B.;
Srirangalingam, Umasuthan;
Guasti, Leonardo;
Chapple, J. Paul;
Trivellin, Giampaolo;
Gueorguiev, Maria;
Guegan, Katie;
Stals, Karen;
Khoo, Bernard;
Kumar, Ajith V.;
Ellard, Sian;
Grossman, Ashley B.;
Korbonits, Márta

Publication type:

Article

Altered Cellular Metabolism Is a Consequence of Loss of the Ataxia-Linked Protein Sacsin.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13242, doi. 10.3390/ijms252413242

By:

Perna, Laura;
Salsbury, Grace;
Dushti, Mohammed;
Smith, Christopher J.;
Morales, Valle;
Bianchi, Katiuscia;
Czibik, Gabor;
Chapple, J. Paul

Publication type:

Article

Polycystin-2 Is Required for Chondrocyte Mechanotransduction and Traffics to the Primary Cilium in Response to Mechanical Stimulation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4313, doi. 10.3390/ijms22094313

By:

Thompson, Clare L.;
McFie, Megan;
Chapple, J. Paul;
Beales, Philip;
Knight, Martin M.;
Bartolak-Suki, Elizabeth

Publication type:

Article

Retinal Imaging in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.

Published in:

Neuro-Ophthalmology, 2011, v. 35, n. 4, p. 197, doi. 10.3109/01658107.2011.595043

By:

Nethisinghe, Suran;
Clayton, Lisa;
Vermeer, Sascha;
Chapple, J. Paul;
Reilly, Mary;
Bremner, Fion;
Giunti, Paola

Publication type:

Article

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 17, p. 3451, doi. 10.1093/hmg/ddx245

By:

Schwarz, Nele;
Lane, Amelia;
Jovanovic, Katarina;
Parfitt, David A.;
Aguila, Monica;
Thompson, Clare L.;
da Cruz, Lyndon;
Coffey, Peter J.;
Chapple, J. Paul;
Hardcastle, Alison J.;
Cheetham, Michael E.

Publication type:

Article

Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 16, p. 3130, doi. 10.1093/hmg/ddx197

By:

Duncan, Emma J.;
Larivière, Roxanne;
Bradshaw, Teisha Y.;
Longo, Fabiana;
Sgarioto, Nicolas;
Hayes, Matthew J.;
Romano, Lisa E. L.;
Nethisinghe, Suran;
Giunti, Paola;
Bruntraeger, Michaela B.;
Durham, Heather D.;
Brais, Bernard;
Maltecca, Francesca;
Gentil, Benoit J.;
Chapple, J. Paul

Publication type:

Article

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 13, p. 2480, doi. 10.1093/hmg/ddx143

By:

Schwarz, Nele;
Lane, Amelia;
Jovanovic, Katarina;
Parfitt, David A.;
Aguila, Monica;
Thompson, Clare L.;
da Cruz, Lyndon;
Coffey, Peter J.;
Chapple, J. Paul;
Hardcastle, Alison J.;
Cheetham, Michael E.

Publication type:

Article

A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 15, p. 3232, doi. 10.1093/hmg/ddw173

By:

Bradshaw, Teisha Y.;
Romano, Lisa E. L.;
Duncan, Emma J.;
Nethisinghe, Suran;
Abeti, Rosella;
Michael, Gregory J.;
Giunti, Paola;
Vermeer, Sascha;
Chapple, J. Paul

Publication type:

Article

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 24, p. 6594, doi. 10.1093/hmg/ddu385

By:

Athanasiou, Dimitra;
Bevilacqua, Dalila;
Aguila, Monica;
McCulley, Caroline;
Kanuga, Naheed;
Iwawaki, Takao;
Paul Chapple, J.;
Cheetham, Michael E.

Publication type:

Article

The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 9, p. 1556, doi. 10.1093/hmg/ddp067

By:

Parfitt, David A.;
Michael, Gregory J.;
Vermeulen, Esmeralda G.M.;
Prodromou, Natalia V.;
Webb, Tom R.;
Gallo, Jean-Marc;
Cheetham, Michael E.;
Nicoll, William S.;
Blatch, Gregory L.;
Chapple, J. Paul

Publication type:

Article

Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4.

Published in:

Human Molecular Genetics, 2007, v. 16, n. 22, p. 2760, doi. 10.1093/hmg/ddm233

By:

Chapple, J. Paul;
Anthony, Karen;
Martin, Teresa Rodriguez;
Dev, Arvind;
Cooper, Thomas A.;
Gallo, Jean-Marc

Publication type:

Article

Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 24, p. 3065, doi. 10.1093/hmg/11.24.3065

By:

Grayson, Celene;
Bartolini, Francesca;
Chapple, J. Paul;
Willison, Keith R.;
Bhamidipati, Arunashree;
Lewis, Sally A.;
Luthert, Philip J.;
Hardcastle, Alison J.;
Cowan, Nicholas J.;
Cheetham, Michael E.

Publication type:

Article

The Leber congenital amaurosis gene product AIPL1 is localized exclusively in rod photoreceptors of the adult human retina.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 7, p. 823, doi. 10.1093/hmg/11.7.823

By:

Spuy, Jacqueline van der;
Chapple, J. Paul;
Clark, Brian J.;
Luthert, Philip J.;
Sethi, Charanjit S.;
Cheetham, Michael E.

Publication type:

Article

Mutations in the N-terminus of the X-linked retinitis pigmentosa protein RP2 interfere with the normal targeting of the protein to the plasma membrane.

Published in:

Human Molecular Genetics, 2000, v. 9, n. 13, p. 1919, doi. 10.1093/hmg/9.13.1919

By:

Chapple, J. Paul

Publication type:

Article

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation.

Published in:

Stem Cells, 2015, v. 33, n. 6, p. 1952, doi. 10.1002/stem.1975

By:

Dalbay, Melis T.;
Thorpe, Stephen D.;
Knight, Martin M.;
Connelly, John T.;
Chapple, J. Paul

Publication type:

Article

Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.

Published in:

Nature Genetics, 2012, v. 44, n. 7, p. 740, doi. 10.1038/ng.2299

By:

Meimaridou, Eirini;
Kowalczyk, Julia;
Guasti, Leonardo;
Hughes, Claire R;
Wagner, Florian;
Frommolt, Peter;
Nürnberg, Peter;
Mann, Nicholas P;
Banerjee, Ritwik;
Saka, H Nurcin;
Chapple, J Paul;
King, Peter J;
Clark, Adrian J L;
Metherell, Louise A

Publication type:

Article

GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23715-7

By:

Callender, Lauren A.;
Schroth, Johannes;
Carroll, Elizabeth C.;
Garrod-Ketchley, Conor;
Romano, Lisa E. L.;
Hendy, Eleanor;
Kelly, Audrey;
Lavender, Paul;
Akbar, Arne N.;
Chapple, J. Paul;
Henson, Sian M.

Publication type:

Article

Sacsin, mutated in the ataxia ARSACS, regulates intermediate filament assembly and dynamics.

Published in:

FASEB Journal, 2019, v. 33, n. 2, p. 2982, doi. 10.1096/fj.201801556R

By:

Gentil, Benoit J.;
Gia-Thanh Lai;
Menade, Marie;
Larivière, Roxanne;
Minotti, Sandra;
Gehring, Kalle;
Chapple, J.-Paul;
Brais, Bernard;
Durham, Heather D.

Publication type:

Article

TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones.

Published in:

Journal of Neurochemistry, 2006, v. 99, n. 3, p. 989, doi. 10.1111/j.1471-4159.2006.04142.x

By:

Hooper, Claudie;
Tavassoli, Mahvash;
Chapple, J. Paul;
Uwanogho, Dafe;
Goodyear, Richard;
Melino, Gerry;
Lovestone, Simon;
Killick, Richard

Publication type:

Article