Works by Changzhi Huang

Results: 36

The E3 Ubiquitin Ligase ARIH1 Facilitates Colorectal Cancer Progression by Promoting Oxidative Phosphorylation via the Mitochondrial Translocation of K63‐Linked Ubiquitinated PHB1.

Published in:

Advanced Science, 2025, v. 12, n. 25, p. 1, doi. 10.1002/advs.202501017

By:

Tong, Ying;
Wang, Zhenling;
Wang, Yong;
Chen, Yang;
Zhang, Hongqiang;
Lu, Yunfei;
Xu, Lei;
Shen, Hengyang;
Huang, Changzhi;
Zhao, Min;
Li, Wenjie;
Wang, Shuai;
Shao, Yu;
Fu, Zan

Publication type:

Article

Associations of serum cystatin C concentrations with total mortality and mortality of 12 site-specific cancers.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1209349

By:

Changzhi Huang;
Jiayi Lu;
Jing Yang;
Zhenling Wang;
Dong Hang;
Zan Fu

Publication type:

Article

Machine learning-based glycolysis-associated molecular classification reveals differences in prognosis, TME, and immunotherapy for colorectal cancer patients.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1181985

By:

Zhenling Wang;
Yu Shao;
Hongqiang Zhang;
Yunfei Lu;
Yang Chen;
Hengyang Shen;
Changzhi Huang;
Jingyu Wu;
Zan Fu

Publication type:

Article

Solute Carrier Family 27 Member 6 (SLC27A6) Possibly Promotes the Proliferation of Papillary Thyroid Cancer by Regulating c-MYC.

Published in:

Biochemical Genetics, 2022, v. 60, n. 6, p. 2313, doi. 10.1007/s10528-022-10218-3

By:

Liu, Changjian;
Wang, Jian;
Li, Dongdong;
Ni, Ruoxuan;
Zhao, Mei;
Huang, ChangZhi;
Liu, Shaoyan

Publication type:

Article

MTA1 regulates higher-order chromatin structure and histone H1-chromatin interaction in-vivo.

Published in:

Molecular Oncology, 2015, v. 9, n. 1, p. 218, doi. 10.1016/j.molonc.2014.08.007

By:

Liu, Jian;
Wang, Haijuan;
Ma, Fei;
Xu, Dongkui;
Chang, Yanan;
Zhang, Jinlong;
Wang, Jia;
Zhao, Mei;
Lin, Chen;
Huang, Changzhi;
Qian, Haili;
Zhan, Qimin

Publication type:

Article

CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 372, n. 1/2, p. 1, doi. 10.1007/s11010-012-1418-4

By:

Zhong, Jialing;
Zhao, Mei;
Luo, Qing;
Ma, Yiming;
Liu, Jian;
Wang, Jia;
Yang, Mei;
Yuan, Xinghua;
Sang, Jianli;
Huang, Changzhi

Publication type:

Article

Integrative genome-wide aberrant DNA methylation and transcriptome analysis identifies diagnostic markers for colorectal cancer.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 2179, doi. 10.1007/s00204-025-03990-9

By:

Shen, Hengyang;
Wang, Zhenling;
Chen, Yang;
Huang, Changzhi;
Xu, Lei;
Tong, Ying;
Zhang, Hongqiang;
Lu, Yunfei;
Li, Shuwei;
Fu, Zan

Publication type:

Article

Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration.

Published in:

Archives of Toxicology, 2024, v. 98, n. 5, p. 1499, doi. 10.1007/s00204-024-03702-9

By:

Shen, Hengyang;
Chen, Yang;
Xu, Menghuan;
Zhou, Jieyu;
Huang, Changzhi;
Wang, Zhenling;
Shao, Yu;
Zhang, Hongqiang;
Lu, Yunfei;
Li, Shuwei;
Fu, Zan

Publication type:

Article

Overexpression of PIP5KL1 suppresses the growth of human cervical cancer cells in vitro and in vivo.

Published in:

Cell Biology International, 2010, v. 34, n. 3, p. 309, doi. 10.1042/CBI20090040

By:

Lan Shi;
Kai Wang;
Mei Zhao;
Xinghua Yuan;
Changzhi Huang

Publication type:

Article

HIST2H2BF Potentiates the Propagation of Cancer Stem Cells via Notch Signaling to Promote Malignancy and Liver Metastasis in Colorectal Carcinoma.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.677646

By:

Qiu, Lei;
Yang, Xiuwei;
Wu, Jingyu;
Huang, Changzhi;
Miao, Yongchang;
Fu, Zan

Publication type:

Article

Vitamin D Receptor-Dependent Protective Effect of Moderate Hypoxia in a Mouse Colitis Model.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.876890

By:

Zheng Wang;
Hong Yang;
Hong Lv;
Changzhi Huang;
Jiaming Qian

Publication type:

Article

Unveiling immunogenic cell death–related genes in colorectal cancer: an integrated study incorporating transcriptome and Mendelian randomization analyses.

Published in:

Functional & Integrative Genomics, 2023, v. 23, n. 4, p. 1, doi. 10.1007/s10142-023-01238-2

By:

Shao, Yu;
Wang, Zhenling;
Wu, Jingyu;
Lu, Yunfei;
Chen, Yang;
Zhang, Hongqiang;
Huang, Changzhi;
Shen, Hengyang;
Xu, Lei;
Fu, Zan

Publication type:

Article

Single-cell and spatial transcriptome profiling reveal CTHRC1+ fibroblasts promote EMT through WNT5A signaling in colorectal cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06236-5

By:

Lu, Yunfei;
Chen, Yang;
Wang, Zhenling;
Shen, Hengyang;
Xu, Lei;
Huang, Changzhi;
Tong, Ying;
Shao, Yu;
Zhang, Hongqiang;
Fu, Zan

Publication type:

Article

LncRNA MIR155HG Overexpression Promotes Proliferation, Migration, and Chemoresistance in Gastric Cancer Cells.

Published in:

International Journal of Medical Sciences, 2023, v. 20, n. 7, p. 933, doi. 10.7150/ijms.82216

By:

Hong Lin;
Ruoxuan Ni;
Dongdong Li;
Mei Zhao;
Yan Li;
Kexin Li;
Qiao Zhang;
Changzhi Huang;
Shengkai Huang

Publication type:

Article

NAIF1 inhibits gastric cancer cells migration and invasion via the MAPK pathways.

Published in:

Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 6, p. 1037, doi. 10.1007/s00432-014-1865-2

By:

Yang, Mei;
Gu, Yu-yu;
Peng, Hua;
Zhao, Mei;
Wang, Jia;
Huang, Sheng-kai;
Yuan, Xing-hua;
Li, Jia;
Sang, Jian-li;
Luo, Qing;
Huang, Changzhi

Publication type:

Article

MiR-494 acts as a tumor promoter by targeting CASP2 in non-small cell lung cancer.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39453-2

By:

Zhang, Qiao;
Li, Yan;
Zhao, Mei;
Lin, Hong;
Wang, Wenjie;
Li, Dongdong;
Cui, Wei;
Zhou, Caihong;
Zhong, Jialing;
Huang, Changzhi

Publication type:

Article

Subtypes analysis and prognostic model construction based on lysosome-related genes in colon adenocarcinoma.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1149995

By:

Yang Chen;
Yunfei Lu;
Changzhi Huang;
Jingyu Wu;
Yu Shao;
Zhenling Wang;
Hongqiang Zhang;
Zan Fu

Publication type:

Article

Subtypes analysis and prognostic model construction based on lysosome-related genes in colon adenocarcinoma.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1149995

By:

Yang Chen;
Yunfei Lu;
Changzhi Huang;
Jingyu Wu;
Yu Shao;
Zhenling Wang;
Hongqiang Zhang;
Zan Fu

Publication type:

Article

Analysis of the Prognostic Significance and Immune Infiltration of the Amino Acid Metabolism-Related Genes in Colon Adenocarcinoma.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.951461

By:

Zhenling Wang;
Changzhi Huang;
Jingyu Wu;
Hongqiang Zhang;
Yu Shao;
Zan Fu

Publication type:

Article

Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer.

Published in:

Oxidative Medicine & Cellular Longevity, 2022, p. 1, doi. 10.1155/2022/7242124

By:

Feng, Yifei;
Wang, Xiaoyuan;
Huang, Changzhi;
Zhang, Dongsheng;
Liu, Tingwei;
Zhang, Chuan;
Zhang, Yue;
Ji, Dongjian;
Tang, Junwei;
Sun, Yueming

Publication type:

Article

Recruitment of USP10 by GCS1 to deubiquitinate GRP78 promotes the progression of colorectal cancer via alleviating endoplasmic reticulum stress.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03176-8

By:

Chen, Yang;
Shen, Hengyang;
Wang, Zhenling;
Huang, Changzhi;
Zhang, Hongqiang;
Shao, Yu;
Tong, Ying;
Xu, Lei;
Lu, Yunfei;
Fu, Zan

Publication type:

Article

Proteomic profiling of proteins associated with lymph node metastasis in colorectal cancer.

Published in:

Journal of Cellular Biochemistry, 2010, v. 110, n. 6, p. 1512, doi. 10.1002/jcb.22726

By:

Ma, Yiming;
Zhao, Mei;
Zhong, Jialing;
Shi, Lan;
Luo, Qing;
Liu, Jian;
Wang, Jia;
Yuan, Xinghua;
Huang, Changzhi

Publication type:

Article

Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.885656

By:

Zheng, Luyu;
Liu, Qun;
Li, Ruijun;
Chen, Shibin;
Tan, Jingyu;
Li, Lina;
Dong, Xichen;
Huang, Changzhi;
Wen, Tao;
Liu, Jian

Publication type:

Article

Serum microRNA expression profile as a diagnostic panel for gastric cancer.

Published in:

Japanese Journal of Clinical Oncology, 2016, v. 46, n. 9, p. 811, doi. 10.1093/jjco/hyw085

By:

Shengkai Huang;
Jia Wang;
Jia Li;
Qing Luo;
Mei Zhao;
Limin Zheng;
Xianzhe Dong;
Chao Chen;
Yiqun Che;
Ping Liu;
Jun Qi;
Changzhi Huang

Publication type:

Article

Association between circulating insulin-like growth factor 1 and risk of all-cause and cause-specific mortality.

Published in:

European Journal of Endocrinology, 2021, v. 185, n. 5, p. 681, doi. 10.1530/EJE-21-0573

By:

Yu Xie;
Changzhi Huang;
Xingchen Zhu;
Jiayu Wang;
Xikang Fan;
Zan Fu;
Yanan Ma;
Dong Hang

Publication type:

Article

scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer.

Published in:

Nucleic Acids Research, 2025, v. 53, n. D1, p. D1526, doi. 10.1093/nar/gkae1100

By:

Huang, Changzhi;
Liu, Zekai;
Guo, Yunlei;
Wang, Wanchu;
Yuan, Zhen;
Guan, Yusheng;
Pan, Deng;
Hu, Zhibin;
Sun, Linhua;
Fu, Zan;
Bian, Shuhui

Publication type:

Article

Knockdown of UBQLN1 Functions as a Strategy to Inhibit CRC Progression through the ERK-c-Myc Pathway.

Published in:

Cancers, 2023, v. 15, n. 12, p. 3088, doi. 10.3390/cancers15123088

By:

Ni, Ruoxuan;
Jiang, Jianwei;
Zhao, Mei;
Huang, Shengkai;
Huang, Changzhi

Publication type:

Article

Hypoxic colorectal cancer‐derived extracellular vesicles deliver microRNA‐361‐3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF‐κB pathways.

Published in:

Clinical & Translational Medicine, 2021, v. 11, n. 3, p. 1, doi. 10.1002/ctm2.349

By:

Li, Jie;
Yang, Peng;
Chen, Fangyu;
Tan, Yuqian;
Huang, Changzhi;
Shen, Hengyang;
Peng, Chaofan;
Feng, Yifei;
Sun, Yueming

Publication type:

Article

Chromatin modifier MTA1 regulates mitotic transition and tumorigenesis by orchestrating mitotic mRNA processing.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18259-1

By:

Liu, Jian;
Li, Chunxiao;
Wang, Jinsong;
Xu, Dongkui;
Wang, Haijuan;
Wang, Ting;
Li, Lina;
Li, Hui;
Nan, Peng;
Zhang, Jingyao;
Wang, Yang;
Huang, Changzhi;
Chen, Dong;
Zhang, Yi;
Wen, Tao;
Zhan, Qimin;
Ma, Fei;
Qian, Haili

Publication type:

Article

Overexpression of Nuclear Apoptosis-Inducing Factor 1 Altered the Proteomic Profile of Human Gastric Cancer Cell MKN45 and Induced Cell Cycle Arrest at G1/S Phase.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100216

By:

Yang, Mei;
Zhong, Jialing;
Zhao, Mei;
Wang, Jia;
Gu, Yuyu;
Yuan, Xinghua;
Sang, Jianli;
Huang, Changzhi

Publication type:

Article

Subcellular localization of MTA proteins in normal and cancer cells.

Published in:

Cancer & Metastasis Reviews, 2014, v. 33, n. 4, p. 843, doi. 10.1007/s10555-014-9511-7

By:

Liu, Jian;
Wang, Haijuan;
Huang, Changzhi;
Qian, Haili

Publication type:

Article

Survey of mosquito species and mosquito-borne viruses in residential areas along the Sino-Vietnam border in Yunnan Province in China.

Published in:

Frontiers in Microbiology, 2023, v. 14, p. 1, doi. 10.3389/fmicb.2023.1105786

By:

Fengjuan Tian;
Jimin He;
Shanlin Shang;
Zhongyan Chen;
Yumei Tang;
Man Lu;
Changzhi Huang;
Xiaofang Guo;
Yigang Tong

Publication type:

Article

CDK12 is a promising therapeutic target for the transcription cycle and DNA damage response in metastatic osteosarcoma.

Published in:

Carcinogenesis, 2024, v. 45, n. 10, p. 786, doi. 10.1093/carcin/bgae051

By:

Li, Zihao;
Li, Xiaoyang;
Seebacher, Nicole A;
Liu, Xu;
Wu, Wence;
Yu, Shengji;
Hornicek, Francis J;
Huang, Changzhi;
Duan, Zhenfeng

Publication type:

Article

Effects of Vitamin D Receptor on Mucosal Barrier Proteins in Colon Cells under Hypoxic Environment.

Published in:

Acta Academiae Medicinae Sinica, 2019, v. 41, n. 4, p. 506, doi. 10.3881/j.issn.1000-503X.11243

By:

WANG Zheng;
YANG Hong;
JIN Meng;
ZHANG Huimin;
CHEN Xuanfu;
WU Meixu;
GUO Mingyue;
HUANG Changzhi;
QIAN Jiaming

Publication type:

Article

Serum Calcium Concentrations and Risk of All-Cause and Cause-Specific Mortality: Results From 2 Prospective Cohorts.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 8, p. e527, doi. 10.1210/clinem/dgad078

By:

Mingjia Yang;
Junyan Miao;
Lingbin Du;
Jiayu Wang;
Jing Yang;
Jiayi Lu;
Xikang Fan;
Changzhi Huang;
Zan Fu;
Zekuan Xu;
Mingyang Song;
Hongxia Ma;
Guangfu Jin;
Zhibin Hu;
Dong Hang;
Hongbing Shen

Publication type:

Article

Overexpression of the Ubiquilin-4 (UBQLN4) is Associated with Cell Cycle Arrest and Apoptosis in Human Normal Gastric Epithelial Cell Lines GES-1 Cells by Activation of the ERK Signaling Pathway.

Published in:

Medical Science Monitor, 2018, v. 24, p. 3564, doi. 10.12659/MSM.909621

By:

Shengkai Huang;
Xin Dong;
Jia Wang;
Jie Ding;
Yan Li;
Dongdong Li;
Hong Lin;
Wenjie Wang;
Mei Zhao;
Qing Chang;
Ning Zhou;
Wei Cui;
Changzhi Huang

Publication type:

Article