Works by Chang, Xiaotian

Results: 52

CXCL10 and TRAIL Are Upregulated by TXNDC5 in Rheumatoid Arthritis Fibroblast-like Synoviocytes.

Published in:

2018

By:

Bing Xu;
Jian Li;
Changsun Wu;
Chunyan Liu;
Xinfeng Yan;
Xiaotian Chang;
Xu, Bing;
Li, Jian;
Wu, Changsun;
Liu, Chunyan;
Yan, Xinfeng;
Chang, Xiaotian

Publication type:

journal article

DNA aptamers targeting glycoprotein D enable specific detection of pseudorabies virus (PRV).

Published in:

Animal Diseases, 2025, v. 5, n. 1, p. 1, doi. 10.1186/s44149-025-00164-z

By:

Wang, Zhihao;
Qiao, Yan;
Zhao, Jiafu;
Chang, Xiaotian;
Zhu, Heshui;
Zhang, Chao

Publication type:

Article

What happens to regulatory T cells in multiple myeloma.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01765-8

By:

Chen, Huixian;
Wang, Xueling;
Wang, Yan;
Chang, Xiaotian

Publication type:

Article

E2F2 stimulates CCR4 expression and activates synovial fibroblast-like cells in rheumatoid arthritis.

Published in:

Central European Journal of Immunology, 2021, v. 46, n. 1, p. 27, doi. 10.5114/ceji.2021.105243

By:

WANJU XU;
SHUFENG LI;
XIAOTIAN CHANG

Publication type:

Article

PADI3 induces cell cycle arrest via the Sirt2/AKT/p21 pathway and acts as a tumor suppressor gene in colon cancer.

Published in:

Cancer Biology & Medicine, 2019, v. 16, n. 4, p. 729, doi. 10.20892/j.issn.2095-3941.2019.0065

By:

Xiaotian Chang;
Zhengbin Chai;
Jiaorui Zou;
Hongxing Wang;
Yao Wang;
Yabing Zheng;
Hui Wu;
Chunyan Liu

Publication type:

Article

Effects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ<sub>1−42</sub> Oligomers Induced Neurotoxicity.

Published in:

Neurochemical Research, 2018, v. 43, n. 10, p. 2008, doi. 10.1007/s11064-018-2622-8

By:

Liu, Yudong;
Zhang, Peng;
Zheng, Yabing;
Yang, Chunlin;
Du, Tong;
Ge, Mengru;
Chang, Xiaotian;
Duan, Ruisheng;
Ma, Guozhao

Publication type:

Article

PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling.

Published in:

Cancer Cell International, 2016, v. 16, p. 1, doi. 10.1186/s12935-016-0335-0

By:

Huifeng Wang;
Bing Xu;
Xiaoqian Zhang;
Yabing Zheng;
Yan Zhao;
Xiaotian Chang

Publication type:

Article

PADI4 and tumourigenesis.

Published in:

Cancer Cell International, 2010, v. 10, p. 7, doi. 10.1186/1475-2867-10-7

By:

Xiaotian Chang;
Kehua Fang

Publication type:

Article

PGK1, a glucose metabolism enzyme, may play an important role in rheumatoid arthritis.

Published in:

Inflammation Research, 2016, v. 65, n. 10, p. 815, doi. 10.1007/s00011-016-0965-7

By:

Zhao, Yan;
Yan, Xinfeng;
Li, Xia;
Zheng, Yabing;
Li, Shufeng;
Chang, Xiaotian

Publication type:

Article

Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer.

Published in:

2019

By:

Liu, Chunyan;
Zheng, Yingying;
Tang, Junyi;
Wang, Dawei;
Ma, Zhenshen;
Li, Shutong;
Chang, Xiaotian

Publication type:

journal article

Strong association of glaucoma with atherosclerosis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88322-4

By:

Song, Xianqin;
Li, Peng;
Li, Yunfeng;
Yan, Xinfeng;
Yuan, Lin;
Zhao, Cong;
An, Yi;
Chang, Xiaotian

Publication type:

Article

High serum mannose in colorectal cancer: a novel biomarker of lymph node metastasis and poor prognosis.

Published in:

Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1213952

By:

Xueling Wang;
Haoran Li;
Xiaotian Chang;
Zibin Tian

Publication type:

Article

Expression of Semaphorin 4A and its potential role in rheumatoid arthritis.

Published in:

Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13075-015-0734-y

By:

Lin Wang;
Guanhua Song;
Yabing Zheng;
Weiwei Tan;
Jihong Pan;
Yu Zhao;
Xiaotian Chang

Publication type:

Article

Expression of Semaphorin 4A and its potential role in rheumatoid arthritis.

Published in:

Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 227, doi. 10.1186/s13075-015-0734-y

By:

Lin Wang;
Guanhua Song;
Yabing Zheng;
Weiwei Tan;
Jihong Pan;
Yu Zhao;
Xiaotian Chang

Publication type:

Article

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.

Published in:

Nature Genetics, 2005, v. 37, n. 5, p. 478, doi. 10.1038/ng1540

By:

Kochi, Yuta;
Yamada, Ryo;
Suzuki, Akari;
Harley, John B;
Shirasawa, Senji;
Sawada, Tetsuji;
Bae, Sang-Cheol;
Tokuhiro, Shinya;
Chang, Xiaotian;
Sekine, Akihiro;
Takahashi, Atsushi;
Tsunoda, Tatsuhiko;
Ohnishi, Yozo;
Kaufman, Kenneth M;
Kang, Changsoo Paul;
Kang, Changwon;
Otsubo, Shigeru;
Yumura, Wako;
Mimori, Akio;
Koike, Takao

Publication type:

Article

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.

Published in:

Nature Genetics, 2003, v. 35, n. 4, p. 341, doi. 10.1038/ng1267

By:

Tokuhiro, Shinya;
Yamada, Ryo;
Suzuki, Akari;
Kochi, Yuta;
Sawada, Tetsuji;
Suzuki, Masakatsu;
Nagasaki, Miyuki;
Ohtsuki, Masahiko;
Ono, Mitsuru;
Chang, Xiaotian;
Furukawa, Hidehiko;
Nagashima, Masakazu;
Yoshino, Shinichi;
Mabuchi, Akihiko;
Sekine, Akihiro;
Saito, Susumu;
Takahashi, Atsushi;
Tsunoda, Tatsuhiko;
Nakamura, Yusuke;
Yamamoto, Kazuhiko

Publication type:

Article

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.

Published in:

Nature Genetics, 2003, v. 34, n. 4, p. 395, doi. 10.1038/ng1206

By:

Suzuki, Akari;
Yamada, Ryo;
Chang, Xiaotian;
Tokuhiro, Shinya;
Sawada, Tetsuji;
Suzuki, Masakatsu;
Nagasaki, Miyuki;
Nakayama-Hamada, Makiko;
Kawaida, Reimi;
Ono, Mitsuru;
Ohtsuki, Masahiko;
Furukawa, Hidehiko;
Yoshino, Shinichi;
Yukioka, Masao;
Tohma, Shigeto;
Matsubara, Tsukasa;
Wakitani, Shigeyuki;
Teshima, Ryota;
Nishioka, Yuichi

Publication type:

Article

Adding salt to foods and risk of incident depression and anxiety.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-03865-x

By:

Wang, Weiwei;
Chang, Xiaotian;
Lin, Feifei;
Feng, Lei;
Wang, Mengying;
Huang, Jie;
Wu, Tao

Publication type:

Article

Expression of PADI4 during rheumatoid arthritis development.

Published in:

Rheumatology Reports, 2009, v. 1, n. 1, p. 7, doi. 10.4081/rr.2009.e3

By:

Cuirong Bian;
Xiaotian Chang;
Yan Zhao;
Jinqiu Jia;
Yunzhong Zhang

Publication type:

Article

Obesity and risk of hearing loss in the middle-aged and elderly: a national cohort of Chinese adults.

Published in:

BMC Public Health, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12889-023-15974-4

By:

Zhang, Chen;
Wang, Weiwei;
Chang, Xiaotian;
Zhan, Siyan;
Wang, Shengfeng;
Feng, Lei;
Song, Yongfeng

Publication type:

Article

Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction.

Published in:

BMC Musculoskeletal Disorders, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2474-13-256

By:

Yabing Zheng;
Lin Wang;
Wei Zhang;
Hengwei Xu;
Xiaotian Chang

Publication type:

Article

Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction.

Published in:

2012

By:

Zheng, Yabing;
Wang, Lin;
Zhang, Wei;
Xu, Hengwei;
Chang, Xiaotian

Publication type:

journal article

Increased expression of carbonic anhydrase I in the synovium of patients with ankylosing spondylitis.

Published in:

BMC Musculoskeletal Disorders, 2010, v. 11, p. 279, doi. 10.1186/1471-2474-11-279

By:

Xiaotian Chang;
Jinxiang Han;
Yan Zhao;
Xinfeng Yan;
Shui Sun;
Yazhou Cui

Publication type:

Article

Uridine Diphosphate Promotes Rheumatoid Arthritis Through P2Y6 Activation.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.658511

By:

Wang, Hongxing;
Wu, Hui;
Fang, Kehua;
Chang, Xiaotian

Publication type:

Article

Increased PADI4 expression in blood and tissues of patients with malignant tumors.

Published in:

2009

By:

Chang X;
Han J;
Pang L;
Zhao Y;
Yang Y;
Shen Z;
Chang, Xiaotian;
Han, Jinxiang;
Pang, Li;
Zhao, Yan;
Yang, Yi;
Shen, Zhonglin

Publication type:

journal article

PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up‐regulates CA9 expression.

Published in:

Molecular Carcinogenesis, 2019, v. 58, n. 1, p. 66, doi. 10.1002/mc.22907

By:

Liu, Chunyan;
Tang, Junyi;
Li, Chang;
Pu, Guangbo;
Yang, Dongxia;
Chang, Xiaotian

Publication type:

Article

Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors.

Published in:

Molecular Carcinogenesis, 2006, v. 45, n. 3, p. 183, doi. 10.1002/mc.20169

By:

Xiaotian Chang;
Jinxiang Han

Publication type:

Article

Therapeutic Effect of Exogenous Regulatory T Cells on Collagen-induced Arthritis and Rheumatoid Arthritis.

Published in:

Cell Transplantation, 2020, v. 29, p. 1, doi. 10.1177/0963689720954134

By:

Li, Shutong;
Wang, Hongxing;
Wu, Hui;
Chang, Xiaotian

Publication type:

Article

The role and mechanism of TXNDC5 in diseases.

Published in:

European Journal of Medical Research, 2022, v. 27, n. 1, p. 1, doi. 10.1186/s40001-022-00770-4

By:

Wang, Xueling;
Li, Haoran;
Chang, Xiaotian

Publication type:

Article

Overexpression of circulating CD38+ NK cells in colorectal cancer was associated with lymph node metastasis and poor prognosis.

Published in:

Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2024.1309785

By:

Xueling Wang;
Haoran Li;
Huixian Chen;
Kehua Fang;
Xiaotian Chang

Publication type:

Article

Tandemly Repeated G-Quadruplex Structures in the Pseudorabies Virus Genome: Implications for Epiberberine-Based Antiviral Therapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3764, doi. 10.3390/ijms26083764

By:

Fan, Songjie;
Chang, Xiaotian;
Qiao, Yan;
Zhao, Xiaoxiao;
Zhao, Jiafu;
Zhu, Heshui;
Han, Yingqian;
Zhang, Chao

Publication type:

Article

The expression of PADI4 in synovium of rheumatoid arthritis.

Published in:

Rheumatology International, 2009, v. 29, n. 12, p. 1411, doi. 10.1007/s00296-009-0870-2

By:

Xiaotian Chang;
Yan Zhao;
Shui Sun;
Yunzhong Zhang;
Youming Zhu

Publication type:

Article

Expression and citrullination of keratin in synovial tissue of rheumatoid arthritis.

Published in:

Rheumatology International, 2009, v. 29, n. 11, p. 1337, doi. 10.1007/s00296-009-0863-1

By:

Xiaotian Chang;
Xiangdong Jian;
Xinfeng Yan

Publication type:

Article

Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis.

Published in:

Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.00766

By:

Yuan, Lin;
Wang, Minghua;
Liu, Tianqi;
Lei, Yinsheng;
Miao, Qiang;
Li, Quan;
Wang, Hongxing;
Zhang, Guoqing;
Hou, Yinglong;
Chang, Xiaotian

Publication type:

Article

M1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs.

Published in:

Journal of Inflammation Research, 2023, v. 16, p. 3019, doi. 10.2147/JIR.S413358

By:

Song, Xianqin;
Song, Yu;
Ma, Quanping;
Fang, Kehua;
Chang, Xiaotian

Publication type:

Article

Investigating the expression, effect and tumorigenic pathway of PADI2 in tumors.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 1475, doi. 10.2147/OTT.S92389

By:

Wei Guo;
Yabing Zheng;
Bing Xu;
Fang Ma;
Chang Li;
Xiaoqian Zhang;
Yao Wang;
Xiaotian Chang

Publication type:

Article

PADI2 Is Significantly Associated with Rheumatoid Arthritis.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081259

By:

Chang, Xiaotian;
Xia, Yifang;
Pan, Jihong;
Meng, Qingsong;
Zhao, Yan;
Yan, Xinfeng

Publication type:

Article

Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053301

By:

Lin Wang;
Yabing Zheng;
Hengwei Xu;
Xinfeng Yan;
Xiaotian Chang

Publication type:

Article

Glycolysis and rheumatoid arthritis.

Published in:

International Journal of Rheumatic Diseases, 2011, v. 14, n. 3, p. 217, doi. 10.1111/j.1756-185X.2011.01598.x

By:

CHANG, Xiaotian;
WEI, Chao

Publication type:

Article

Differences in the Association Between Modifiable Lifestyle Factors and Gastric Precancerous Lesions Among Mongolians and Han Chinese.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.798829

By:

Wang, Weiwei;
Qiao, Liying;
Dong, Weiqi;
Ren, Jing;
Chang, Xiaotian;
Zhan, Siyan;
Du, Peng;
Xi, Yunfeng;
Wang, Shengfeng

Publication type:

Article

Circulating Glycan Monosaccharide Composite-Based Biomarker Diagnoses Colorectal Cancer at Early Stages and Predicts Prognosis.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.852044

By:

Li, Haoran;
Wang, Xueling;
Huang, Xiaodan;
He, Yanli;
Zhang, Yiran;
Hao, Cui;
Zeng, Pengjiao;
Zhang, Meng;
Gao, Yanyun;
Yang, Dandan;
Shan, Ming;
Dou, Huaiqian;
Li, Xiaoyu;
Chang, Xiaotian;
Tian, Zibin;
Zhang, Lijuan

Publication type:

Article

T-Cell Immune Imbalance in Rheumatoid Arthritis Is Associated with Alterations in NK Cells and NK-Like T Cells Expressing CD38.

Published in:

Journal of Innate Immunity, 2022, v. 14, n. 2, p. 148, doi. 10.1159/000516642

By:

Wang, Hongxing;
Fang, Kehua;
Yan, Weining;
Chang, Xiaotian

Publication type:

Article

Carbonic anhydrase I (CA1) is involved in the process of bone formation and is susceptible to ankylosing spondylitis.

Published in:

Arthritis Research & Therapy, 2012, v. 14, n. 4, p. 3929, doi. 10.1186/ar3929

By:

Chang, Xiaotian;
Zheng, Yabing;
Yang, Qingrui;
Wang, Lin;
Pan, Jihong;
Xia, Yifang;
Yan, Xinfeng;
Han, Jinxiang

Publication type:

Article

Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis.

Published in:

Arthritis Research & Therapy, 2011, v. 13, n. 4, p. 1, doi. 10.1186/ar3429

By:

Xiaotian Chang;
Yan Zhao;
Xinfeng Yan;
Jihong Pan;
Kehua Fang;
Lin Wang

Publication type:

Article

Aggrecanases in the human synovial fluid at different stages of osteoarthritis.

Published in:

Clinical Rheumatology, 2013, v. 32, n. 6, p. 797, doi. 10.1007/s10067-013-2171-0

By:

Zhang, Enshui;
Yan, Xinfeng;
Zhang, Ming;
Chang, Xiaotian;
Bai, Zhengwu;
He, Yeteng;
Yuan, Zhen

Publication type:

Article

Investigating the cell membrane localization of PADI4 in breast cancer cells and inhibition of anti-PADI4 monoclonal antibody.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 19, p. 17253, doi. 10.1007/s00432-023-05433-3

By:

Wang, Yan;
Song, Xianqin;
Song, Yu;
Fang, Kehua;
Chang, Xiaotian

Publication type:

Article

Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas.

Published in:

Journal of Cancer Research & Clinical Oncology, 2009, v. 135, n. 1, p. 91, doi. 10.1007/s00432-008-0435-x

By:

Wei Zhou;
Zheng Jiang;
Ningbo Liu;
Fenghua Xu;
Peie Wen;
Yanbing Liu;
Weixia Zhong;
Xianrang Song;
Xiaotian Chang;
Xiuli Zhang;
Guangsheng Wei;
Jinming Yu

Publication type:

Article

CD38 modulates cytokine secretion by NK cells through the Sirt1/NF-κB pathway, suppressing immune surveillance in colorectal cancer.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-79008-8

By:

Wang, Xueling;
Song, Xianqin;
Fang, Kehua;
Chang, Xiaotian

Publication type:

Article

2-Deoxy-D-glucose Alleviates Collagen-Induced Arthritis of Rats and Is Accompanied by Metabolic Regulation of the Spleen and Liver.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.713799

By:

Wang, Hongxing;
Zhang, Nanyang;
Fang, Kehua;
Chang, Xiaotian

Publication type:

Article

Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation.

Published in:

Arthritis Research & Therapy, 2019, v. 21, n. 1, p. 1, doi. 10.1186/s13075-019-2001-0

By:

Wang, Hongxing;
Li, Shutong;
Zhang, Guoqing;
Wu, Hui;
Chang, Xiaotian

Publication type:

Article