Works by Chan, Michael C. W.

Results: 42

Dynamic Interaction Between SARS-CoV-2 and Influenza A Virus Infection in Human Respiratory Tissues and Cells.

Published in:

Microorganisms, 2025, v. 13, n. 5, p. 988, doi. 10.3390/microorganisms13050988

By:

Ho, John C. W.;
Ng, Kachun;
Ching, Rachel H. H.;
Peiris, Malik;
Nicholls, John M.;
Chan, Michael C. W.;
Hui, Kenrie P. Y.

Publication type:

Article

Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung.

Published in:

Emerging Infectious Diseases, 2023, v. 29, n. 6, p. 1210, doi. 10.3201/eid2906.221680

By:

Hui, Kenrie P. Y.;
Ho, John C. W.;
Ka-Chun Ng;
Cheng, Samuel M. S.;
Sit, Ko-Yung;
Au, Timmy W. K.;
Poon, Leo L. M.;
Nicholls, John M.;
Peiris, Malik;
Chan, Michael C. W.

Publication type:

Article

Risk Assessment for Highly Pathogenic Avian Influenza A(H5N6/H5N8) Clade 2.3.4.4 Viruses.

Published in:

2021

By:

Bui, Christine H. T.;
Kuok, Denise I. T.;
Hin Wo Yeung;
Ka-Chun Ng;
Chu, Daniel K. W.;
Webby, Richard J.;
Nicholls, John M.;
Peiris, J. S. Malik;
Hui, Kenrie P. Y.;
Chan, Michael C. W.;
Yeung, Hin Wo;
Ng, Ka-Chun

Publication type:

journal article

Introduction of ORF3a-Q57H SARS-CoV-2 Variant Causing Fourth Epidemic Wave of COVID-19, Hong Kong, China.

Published in:

2021

By:

Chu, Daniel K. W.;
Hui, Kenrie P. Y.;
Haogao Gu;
Ko, Ronald L. W.;
Krishnan, Pavithra;
Ng, Daisy Y. M.;
Liu, Gigi Y. Z.;
Wan, Carrie K. C.;
Man-Chun Cheung;
Ka-Chun Ng;
Nicholls, John M.;
Tsang, Dominic N. C.;
Peiris, Malik;
Chan, Michael C. W.;
Poon, Leo L. M.;
Gu, Haogao;
Cheung, Man-Chun;
Ng, Ka-Chun

Publication type:

journal article

DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. 2, p. 275, doi. 10.1093/jac/dkp421

By:

Triana-Baltzer, Gallen B.;
Babizki, Maria;
Chan, Michael C. W.;
Wong, Adam C. N.;
Aschenbrenner, Laura M.;
Campbell, Erin R.;
Qi-Xiang Li;
Chan, Renee W. Y.;
Peiris, J. S. Malik;
Nicholls, John M.;
Fang Fang

Publication type:

Article

Proinflammatory Cytokine Response and Viral Replication in Mouse Bone Marrow Derived Macrophages Infected with Influenza H1N1 and H5N1 Viruses.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0051057

By:

Chan, Renee W. Y.;
Leung, Connie Y. H.;
Nicholls, John M.;
Peiris, J. S. Malik;
Chan, Michael C. W.

Publication type:

Article

Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013927

By:

Danlin Jia;
Rahbar, Ramtin;
Chan, Renee W. Y.;
Lee, Suki M. Y.;
Chan, Michael C. W.;
Ben Xuhao Wang;
Baker, Darren P.;
Bing Sun;
Peiris, J. S. Malik;
Nicholls, John M.;
Fish, Eleanor N.

Publication type:

Article

Influenza H5N1 and H1N1 Virus Replication and Innate Immune Responses in Bronchial Epithelial Cells Are Influenced by the State of Differentiation.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008713

By:

Chan, Renee W. Y.;
Yuen, Kit M.;
Yu, Wendy C. L.;
Ho, Carol C. C.;
Nicholls, John M.;
Peiris, J. S. Malik;
Chan, Michael C. W.

Publication type:

Article

Full Factorial Analysis of Mammalian and Avian Influenza Polymerase Subunits Suggests a Role of an Efficient Polymerase for Virus Adaptation.

Published in:

PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005658

By:

Li, Olive T. W.;
Chan, Michael C. W.;
Leung, Cynthia S. W.;
Chan, Renee W. Y.;
Yi Guan;
Nicholls, John M.;
Poon, Leo L. M.

Publication type:

Article

Synthetic Models of Weak Attractive Ligand-Polymer Interactions in Olefin Polymerization Catalysts.

Published in:

Macromolecular Chemistry & Physics, 2007, v. 208, n. 17, p. 1845, doi. 10.1002/macp.200700322

By:

Chan, Michael C. W.

Publication type:

Article

Shape-Persistent (Pt-salphen)2 Phosphorescent Coordination Frameworks: Structural Insights and Selective Perturbations.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 27, p. 8937, doi. 10.1002/chem.201300421

By:

Guo, Zhengqing;
Yiu, Shek‐Man;
Chan, Michael C. W.

Publication type:

Article

Scalar Coupling Across [CH⋅⋅⋅FC] Interactions in (σ-Aryl)-Chelating Post-Metallocenes.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 2, p. 565, doi. 10.1002/chem.201102439

By:

So, Loi-Chi;
Liu, Cham-Chuen;
Chan, Michael C. W.;
Lo, Jerry C. Y.;
Sze, Kong-Hung;
Zhu, Nianyong

Publication type:

Article

Cover Picture: Scalar Coupling Across [CH⋅⋅⋅FC] Interactions in (σ-Aryl)-Chelating Post-Metallocenes (Chem. Eur. J. 2/2012).

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 2, p. 381, doi. 10.1002/chem.201290000

By:

So, Loi-Chi;
Liu, Cham-Chuen;
Chan, Michael C. W.;
Lo, Jerry C. Y.;
Sze, Kong-Hung;
Zhu, Nianyong

Publication type:

Article

Shape-Persistent Binuclear Cyclometalated Platinum(II) Luminophores: Pushing π-Mediated Excimeric Fluid Emissions into the NIR Region and Ion-Induced Perturbations.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 46, p. 12585, doi. 10.1002/chem.200902328

By:

Guo, Zhengqing;
Chan, Michael C. W.

Publication type:

Article

Weak Attractive Ligand-Polymer and Related Interactions in Catalysis and Reactivity: Impact, Applications, and Modeling.

Published in:

Chemistry - An Asian Journal, 2008, v. 3, n. 1, p. 18, doi. 10.1002/asia.200700226

By:

Chan, Michael C. W.

Publication type:

Article

Saccharide‐Functionalized Poly(Zn‐salphen)‐alt‐(m‐ and p‐phenyleneethynylene)s as Dynamic Helical Metallopolymers.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 9, p. 1, doi. 10.1002/anie.202115712

By:

Zhao, Chao;
Meng, Shuangshuang;
Chan, Hei‐Nga;
Wang, Xueli;
Li, Hung‐Wing;
Chan, Michael C. W.

Publication type:

Article

Host DNA released by NETosis in neutrophils exposed to seasonal H1N1 and highly pathogenic H5N1 influenza viruses.

Published in:

2020

By:

Chan, Louisa L. Y.;
Nicholls, John M.;
Peiris, J. S. Malik;
Lau, Yu Lung;
Chan, Michael C. W.;
Chan, Renee W. Y.

Publication type:

journal article

Evaluation of the human adaptation of influenza A/H7N9 virus in PB2 protein using human and swine respiratory tract explant cultures.

Published in:

Scientific Reports, 2016, p. 35401, doi. 10.1038/srep35401

By:

Chan, Louisa L. Y.;
Bui, Christine T. H.;
Mok, Chris K. P.;
Ng, Mandy M. T.;
Nicholls, John M.;
Peiris, J. S. Malik;
Chan, Michael C. W.;
Chan, Renee W. Y.

Publication type:

Article

Highly pathogenic avian influenza H5N1 virus delays apoptotic responses via activation of STAT3.

Published in:

Scientific Reports, 2016, p. 28593, doi. 10.1038/srep28593

By:

Hui, Kenrie P. Y.;
Li, Hung Sing;
Cheung, Man Chun;
Chan, Renee W. Y.;
Yuen, Kit M.;
Mok, Chris K. P.;
Nicholls, John M.;
Peiris, J. S. Malik;
Chan, Michael C. W.

Publication type:

Article

Olefin Polymerization Reactivity of Group 4 Post‐Metallocene Catalysts Bearing a Four‐Membered C(sp3)‐Donor Chelate Ring.

Published in:

ChemCatChem, 2019, v. 11, n. 1, p. 628, doi. 10.1002/cctc.201801008

By:

Liu, Cham‐Chuen;
Liu, Qian;
Lo, Po‐Kam;
Lau, Kai‐Chung;
Yiu, Shek‐Man;
Chan, Michael C. W.

Publication type:

Article

Mitochondria-targeted platinum(ii) complexes: dual inhibitory activities on tumor cell proliferation and migration/invasion via intracellular trafficking of β-catenin.

Published in:

Metallomics, 2017, v. 9, n. 6, p. 726, doi. 10.1039/c6mt00188b

By:

Li, Jingling;
He, Xiaoli;
Zou, Yeling;
Chen, Dandan;
Yang, Liecheng;
Rao, Jiaming;
Chen, Huabing;
Chan, Michael C. W.;
Li, Lin;
Guo, Zhengqing;
Zhang, Leshuai W.;
Chen, Chunying

Publication type:

Article

Structural Basis for Vapoluminescent Organoplatinum Materials Derived from Noncovalent Interactions as Recognition Components.

Published in:

Chemistry - A European Journal, 2003, v. 9, n. 24, p. 6155, doi. 10.1002/chem.200305322

By:

Wei Lu;
Michael C. W. Chan;
Nianyong Zhu;
Chi-Ming Che;
Zhike He;
Kwok-Yin Wong

Publication type:

Article

Cover Picture: Structural Basis for Vapoluminescent Organoplatinum Materials Derived from Noncovalent Interactions as Recognition Components (Chem. Eur. J. 24/2003).

Published in:

Chemistry - A European Journal, 2003, v. 9, n. 24, p. 5951, doi. 10.1002/chem.200390270

By:

Wei Lu;
Michael C. W. Chan;
Nianyong Zhu;
Chi-Ming Che;
Zhike He;
Kwok-Yin Wong

Publication type:

Article

Structural, Photophysical, and Electrophosphorescent Properties of Platinum( II) Complexes Supported by Tetradentate N2O2 Chelates.

Published in:

Chemistry - A European Journal, 2003, v. 9, n. 6, p. 1263, doi. 10.1002/chem.200390143

By:

Lin, Yong-Yue;
Chan, Siu-Chung;
Chan, Michael C. W.;
Hou, Yuan-Jun;
Zhu, Nianyong;
Che, Chi-Ming;
Liu, Yu;
Wang, Yue

Publication type:

Article

Organic Light-Emitting Materials Based on Bis(arylacetylide)platinum( II) Complexes Bearing Substituted Bipyridine and Phenanthroline Ligands: Photo- and Electroluminescence from 3MLCT Excited States.

Published in:

Chemistry - A European Journal, 2001, v. 7, n. 19, p. 4180, doi. 10.1002/1521-3765(20011001)7:19<4180::AID-CHEM4180>3.0.CO;2-9

By:

Chan, Siu-Chung;
Chan, Michael C. W.;
Wang, Yue;
Che, Chi-Ming;
Cheung, Kung-Kai;
Zhu, Nianyong

Publication type:

Article

Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro.

Published in:

Respiratory Research, 2010, v. 11, p. 147, doi. 10.1186/1465-9921-11-147

By:

Lee, Suki M. Y.;
Chan, Renee W. Y.;
Gardy, Jennifer L.;
Cheuk-kin Lo;
Sihoe, Alan D. L.;
Kang, Sara S. R.;
Cheung, Timothy K. W.;
Yi Guan;
Chan, Michael C. W.;
Hancock, Robert E. W.;
Peiris, Malik J. S.

Publication type:

Article

Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells.

Published in:

2009

By:

Chan MC;
Chan RW;
Yu WC;
Ho CC;
Chui W;
Lo C;
Yuen KM;
Guan Y;
Nicholls JM;
Peiris JM;
Chan, Michael C W;
Chan, Renee W Y;
Yu, Wendy C L;
Ho, Carol C C;
Chui, W H;
Lo, C K;
Yuen, Kit M;
Guan, Y I;
Nicholls, John M;
Peiris, J S Malik

Publication type:

journal article

An interferon-stimulated long non-coding RNA USP30-AS1 as an immune modulator in influenza A virus infection.

Published in:

PLoS Pathogens, 2025, v. 21, n. 1, p. 1, doi. 10.1371/journal.ppat.1012854

By:

Cao, Yi;
Chin, Alex W. H.;
Gu, Haogao;
Li, Mengting;
Gu, Yuner;
Lau, Sylvia P. N.;
Hui, Kenrie P. Y.;
Chan, Michael C. W.;
Poon, Leo L. M.

Publication type:

Article

Observation of Intramolecular C—H···F—C Contacts in Non-Metallocene Polyolefin Catalysts: Model for Weak Attractive Interactions between Polymer Chain and Noninnocent Ligand ( We acknowledge financial support from the Research Grants Council of the Hong Kong SAR, China (HKU 7095/00P) and The University of Hong Kong (URC-administered Seed Funding Grant). We are grateful to Prof. Chi-Ming Che for supporting this work and for his invaluable suggestions. )

Published in:

Angewandte Chemie International Edition, 2003, v. 42, n. 14, p. 1628, doi. 10.1002/anie.200219832

By:

Steven C. F. Kui;
Nianyong Zhu;
Michael C. W. Chan

Publication type:

Article

Stability of SARS-CoV-2 on Commercial Aircraft Interior Surfaces with Implications for Effective Control Measures.

Published in:

International Journal of Environmental Research & Public Health, 2023, v. 20, n. 16, p. 6598, doi. 10.3390/ijerph20166598

By:

Hui, Kenrie P. Y.;
Chin, Alex W. H.;
Ehret, John;
Ng, Ka-Chun;
Peiris, Malik;
Poon, Leo L. M.;
Wong, Karen H. M.;
Chan, Michael C. W.;
Hosegood, Ian;
Nicholls, John M.

Publication type:

Article

Molecular Detection of Human H7N9 Influenza A Virus Causing Outbreaks in China.

Published in:

Clinical Chemistry, 2013, v. 59, n. 7, p. 1062, doi. 10.1373/clinchem.2013.208975

By:

Wong, Chloe K. S.;
Huachen Zhu;
Li, Olive T. W.;
Yin Hung C. Leung;
Chan, Michael C. W.;
Yi Guan;
Peiris, Joseph S. M.;
Poon, Leo L. M.

Publication type:

Article

Saccharide‐Functionalized Poly(Zn‐salphen)‐alt‐(m‐ and p‐phenyleneethynylene)s as Dynamic Helical Metallopolymers.

Published in:

Angewandte Chemie, 2022, v. 134, n. 9, p. 1, doi. 10.1002/ange.202115712

By:

Zhao, Chao;
Meng, Shuangshuang;
Chan, Hei‐Nga;
Wang, Xueli;
Li, Hung‐Wing;
Chan, Michael C. W.

Publication type:

Article

Tropism of SARS-CoV-2, SARS-CoV and influenza virus in canine tissue explants.

Published in:

2021

By:

Bui, Christine H T;
Yeung, Hin Wo;
Ho, John C W;
Leung, Connie Y H;
Hui, Kenrie P Y;
Perera, Ranawaka A P M;
Webby, Richard J;
Schultz-Cherry, Stacey L;
Nicholls, John M;
Peiris, Joseph Sriyal Malik;
Chan, Michael C W;
Yeung, H W;
Peiris, J S Malik

Publication type:

journal article

Risk Assessment of the Tropism and Pathogenesis of the Highly Pathogenic Avian Influenza A/H7N9 Virus Using Ex Vivo and In Vitro Cultures of Human Respiratory Tract.

Published in:

2019

By:

Chan, Louisa L Y;
Hui, Kenrie P Y;
Kuok, Denise I T;
Bui, Christine H T;
Ng, Ka-chun;
Mok, Chris K P;
Yang, Zi-feng;
Guan, Wenda;
Poon, Leo L M;
Zhong, Nanshan;
Peiris, J S Malik;
Nicholls, John M;
Chan, Michael C W

Publication type:

journal article

Cross-species spill-over potential of the H9N2 bat influenza A virus.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47635-4

By:

El-Shesheny, Rabeh;
Franks, John;
Kandeil, Ahmed;
Badra, Rebecca;
Turner, Jasmine;
Seiler, Patrick;
Marathe, Bindumadhav M.;
Jeevan, Trushar;
Kercher, Lisa;
Meng Hu;
Yul Eum Sim;
Hui, Kenrie P. Y.;
Chan, Michael C. W.;
Thompson, Andrew J.;
McKenzie, Pamela;
Govorkova, Elena A.;
Russell, Charles J.;
Vogel, Peter;
Paulson, James C.;
Malik Peiris, J. S.

Publication type:

Article

Infection of swine ex vivo tissues with avian viruses including H7N9 and correlation with glycomic analysis.

Published in:

Influenza & Other Respiratory Viruses, 2013, v. 7, n. 6, p. 1269, doi. 10.1111/irv.12144

By:

Chan, Renee W. Y.;
Karamanska, Rositsa;
Van Poucke, Sjouke;
Van Reeth, Kristien;
Chan, Icarus W. W.;
Chan, Michael C. W.;
Dell, Anne;
Peiris, Joseph S. M.;
Haslam, Stuart M.;
Guan, Yi;
Nicholls, John M.

Publication type:

Article

Replication and innate host response of influenza A virus in lung microvascular endothelial cells: new insights into systemic infection and pathogenesis.

Published in:

Influenza & Other Respiratory Viruses, 2011, v. 5, p. 287

By:

Li, Alan C. L.;
Chan, Renee W. Y.;
Hui, Celine F. F.;
Kang, Sara S. R.;
Yu, Wendy C. L.;
Nicholls, John M.;
Chan, Michael C. W.

Publication type:

Article

Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus-Associated Acute Lung Injury.

Published in:

2019

By:

Loy, Hayley;
Kuok, Denise I T;
Hui, Kenrie P Y;
Choi, Miranda H L;
Yuen, W;
Nicholls, John M;
Peiris, J S Malik;
Chan, Michael C W

Publication type:

journal article

H5N1 Influenza Virus-Induced Mediators Upregulate RIG-I in Uninfected Cells by Paracrine Effects Contributing to Amplified Cytokine Cascades.

Published in:

Journal of Infectious Diseases, 2011, v. 204, n. 12, p. 1866, doi. 10.1093/infdis/jir665

By:

Hui, Kenrie P. Y.;
Lee, Suki M. Y.;
Chung-yan Cheung;
Huawei Mao;
Lai, Angela K. W.;
Chan, Renee W. Y.;
Chan, Michael C. W.;
Wenwei Tu;
Yi Guan;
Yu-Lung Lau;
Peiris, J. S. M.

Publication type:

Article

H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades.

Published in:

2011

By:

Hui KP;
Lee SM;
Cheung CY;
Mao H;
Lai AK;
Chan RW;
Chan MC;
Tu W;
Guan Y;
Lau YL;
Peiris JS;
Hui, Kenrie P Y;
Lee, Suki M Y;
Cheung, Chung-Yan;
Mao, Huawei;
Lai, Angela K W;
Chan, Renee W Y;
Chan, Michael C W;
Tu, Wenwei;
Guan, Yi

Publication type:

journal article

Observation of Intramolecular C—H···F—C Contacts in Non-Metallocene Polyolefin Catalysts: Model for Weak Attractive Interactions between Polymer Chain and Noninnocent Ligand ( We acknowledge financial support from the Research Grants Council of the Hong Kong SAR, China (HKU 7095/00P) and The University of Hong Kong (URC-administered Seed Funding Grant). We are grateful to Prof. Chi-Ming Che for supporting this work and for his invaluable suggestions. )

Published in:

Angewandte Chemie, 2003, v. 115, n. 14, p. 1666, doi. 10.1002/ange.200219832

By:

Steven C. F. Kui;
Nianyong Zhu;
Michael C. W. Chan

Publication type:

Article

Production of amphiregulin and recovery from influenza is greater in males than females.

Published in:

Biology of Sex Differences, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13293-018-0184-8

By:

Vermillion, Meghan S.;
Ursin, Rebecca L.;
Kuok, Denise I. T.;
vom Steeg, Landon G.;
Wohlgemuth, Nicholas;
Hall, Olivia J.;
Fink, Ashley L.;
Sasse, Eric;
Nelson, Andrew;
Ndeh, Roland;
McGrath-Morrow, Sharon;
Mitzner, Wayne;
Chan, Michael C. W.;
Pekosz, Andrew;
Klein, Sabra L.

Publication type:

Article