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Development and characterisation of monoclonal antibodies specific for the murine inhibitory Fcγ RIIB ( CD32 B).
Published in:
European Journal of Immunology, 2012, v. 42, n. 8, p. 2109, doi. 10.1002/eji.201142302
By:
- Williams, Emily L.;
- Tutt, Alison L.;
- French, Ruth R.;
- Chan, H. T. Claude;
- Lau, Betty;
- Penfold, Christine A.;
- Mockridge, C. Ian;
- Roghanian, Ali;
- Cox, Kerry L.;
- Verbeek, J. Sjef;
- Glennie, Martin J.;
- Cragg, Mark S.
Publication type:
Article
Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells.
Published in:
2009
By:
- Ivanov, Andrei;
- Beers, Stephen A.;
- Walshe, Claire A.;
- Honeychurch, Jamie;
- Alduaij, Waleed;
- Cox, Kerry L.;
- Potter, Kathleen N.;
- Murray, Stephen;
- Chan, Claude H. T.;
- Klymenko, Tetyana;
- Erenpreisa, Jekaterina;
- Glennie, Martin J.;
- Illidge, Tim M.;
- Cragg, Mark S.
Publication type:
journal article
Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03182-6
By:
- Heckel, Franziska;
- Turaj, Anna H.;
- Fisher, Hayden;
- Chan, H. T. Claude;
- Marshall, Michael J. E.;
- Dadas, Osman;
- Penfold, Christine A.;
- Inzhelevskaya, Tatyana;
- Mockridge, C. Ian;
- Alvarado, Diego;
- Tews, Ivo;
- Keler, Tibor;
- Beers, Stephen A.;
- Cragg, Mark S.;
- Lim, Sean H.
Publication type:
Article
TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02309-5
By:
- Yu, Xiaojie;
- James, Sonya;
- Felce, James H.;
- Kellermayer, Blanka;
- Johnston, David A.;
- Chan, H. T. Claude;
- Penfold, Christine A.;
- Kim, Jinny;
- Inzhelevskaya, Tatyana;
- Mockridge, C. Ian;
- Watanabe, Yasunori;
- Crispin, Max;
- French, Ruth R.;
- Duriez, Patrick J.;
- Douglas, Leon R.;
- Glennie, Martin J.;
- Cragg, Mark S.
Publication type:
Article
Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1252274
By:
- Dadas, Osman;
- Allen, Joel D.;
- Buchan, Sarah L.;
- Kim, Jinny;
- Claude Chan, H. T.;
- Mockridge, C. Ian;
- Duriez, Patrick J.;
- Rogel, Anne;
- Crispin, Max;
- Al-Shamkhani, Aymen
Publication type:
Article
Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Published in:
Science Immunology, 2022, v. 7, n. 73, p. 1, doi. 10.1126/sciimmunol.abm3723
By:
- Orr, Christian M.;
- Fisher, Hayden;
- Yu, Xiaojie;
- Chan, Claude H.-T.;
- Gao, Yunyun;
- Duriez, Patrick J.;
- Booth, Steven G.;
- Elliott, Isabel;
- Inzhelevskaya, Tatyana;
- Mockridge, Ian;
- Penfold, Christine A.;
- Wagner, Armin;
- Glennie, Martin J.;
- White, Ann L.;
- Essex, Jonathan W.;
- Pearson, Arwen R.;
- Cragg, Mark S.;
- Tews, Ivo
Publication type:
Article
Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses.
Published in:
European Journal of Immunology, 2002, v. 32, n. 12, p. 3617, doi. 10.1002/1521-4141(200212)32:12<3617::AID-IMMU3617>3.0.CO;2-M
By:
- Taraban, Vadim Y.;
- Rowley, Tania F.;
- O'Brien, Lyn;
- Chan, H. T. Claude;
- Haswell, Linsey E.;
- Green, Michael H. A.;
- Tutt, Alison L.;
- Glennie, Martin J.;
- Al-Shamkhani, Aymen
Publication type:
Article

Found: 7

Development and characterisation of monoclonal antibodies specific for the murine inhibitory Fcγ RIIB ( CD32 B).

Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells.

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering.

TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity.

Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc.

Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.

Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses.