Works matching AU Chan, Edward Wai Chi

Results: 61

Recombination of plasmids in a carbapenem-resistant NDM-5-producing clinical Escherichia coli isolate.

Published in:

2018

By:

Miaomiao Xie;
Ruichao Li;
Zhonghua Liu;
Wai Chi Chan, Edward;
Sheng Chen;
Xie, Miaomiao;
Li, Ruichao;
Liu, Zhonghua;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

journal article

IS26-mediated formation of a virulence and resistance plasmid in Salmonella Enteritidis.

Published in:

2017

By:

Ho-yin Wong, Marcus;
Wai-chi Chan, Edward;
Sheng Chen;
Wong, Marcus Ho-Yin;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

journal article

Evolution and comparative genomics of pAQU-like conjugative plasmids in Vibrio species.

Published in:

2017

By:

Ruichao Li;
Lianwei Ye;
Ho Yin Wong, Marcus;
Zhiwei Zheng;
Wai Chi Chan, Edward;
Sheng Chen;
Li, Ruichao;
Ye, Lianwei;
Wong, Marcus Ho Yin;
Zheng, Zhiwei;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

journal article

Complete genetic analysis of plasmids carrying mcr-1 and other resistance genes in an Escherichia coli isolate of animal origin.

Published in:

2017

By:

Ruichao Li;
Miaomiao Xie;
Jingzhang Lv;
Edward Wai-Chi Chan;
Sheng Chen;
Li, Ruichao;
Xie, Miaomiao;
Lv, Jingzhang;
Wai-Chi Chan, Edward;
Chen, Sheng

Publication type:

journal article

Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant.

Published in:

2017

By:

Ruichao Li;
Miaomiao Xie;
Jinfei Zhang;
Zhiqiang Yang;
Lizhang Liu;
Xiaobo Liu;
Zhiwei Zheng;
Edward Wai-Chi Chan;
Sheng Chen;
Li, Ruichao;
Xie, Miaomiao;
Zhang, Jinfei;
Yang, Zhiqiang;
Liu, Lizhang;
Liu, Xiaobo;
Zheng, Zhiwei;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

journal article

Deciphering comprehensive profiles of pathogenies and resistome of pork using integrating metagenomic and isolation strategies.

Published in:

iMetaOmics, 2025, v. 2, n. 2, p. 1, doi. 10.1002/imo2.70004

By:

Ye, Lianwei;
Hu, Qiao;
Zang, Tao;
Wang, Yaling;
Heng, Heng;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Otilonium bromide boosts antimicrobial activities of colistin against Gram-negative pathogens and their persisters.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03561-z

By:

Xu, Chen;
Liu, Chenyu;
Chen, Kaichao;
Zeng, Ping;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Functional and phylogenetic analysis of TetX variants to design a new classification system.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03465-y

By:

Cheng, Qipeng;
Cheung, Yanchu;
Liu, Chenyu;
Chan, Edward Wai Chi;
Wong, Kwok Yin;
Zhang, Rong;
Chen, Sheng

Publication type:

Article

Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02612-1

By:

Wang, Miaomiao;
Chan, Edward Wai Chi;
Wan, Yingkun;
Wong, Marcus Ho-yin;
Chen, Sheng

Publication type:

Article

Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02148-4

By:

Xie, Miaomiao;
Yang, Xuemei;
Xu, Qi;
Ye, Lianwei;
Chen, Kaichao;
Zheng, Zhiwei;
Dong, Ning;
Sun, Qiaoling;
Shu, Lingbin;
Gu, Danxia;
Chan, Edward Wai-Chi;
Zhang, Rong;
Chen, Sheng

Publication type:

Article

Distinct mechanisms of acquisition of mcr-1 –bearing plasmid by Salmonella strains recovered from animals and food samples.

Published in:

Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-01810-4

By:

Cui, Mingquan;
Zhang, Jinfei;
Zhang, Chunping;
Li, Ruichao;
Wai-chi Chan, Edward;
Wu, Chenbin;
Wu, Congming;
Chen, Sheng

Publication type:

Article

Genetic and Functional Characterization of a Conjugative KpVP-2-Type Virulence Plasmid From a Clinical Klebsiella pneumoniae Strain.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.914884

By:

Xuemei Yang;
Xiaoxuan Liu;
Yating Xu;
Chen Yang;
Chan, Edward Wai-Chi;
Hoi-ping Shum;
Sheng Chen

Publication type:

Article

High-Resolution Metagenomics of Human Gut Microbiota Generated by Nanopore and Illumina Hybrid Metagenome Assembly.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.801587

By:

Ye, Lianwei;
Dong, Ning;
Xiong, Wenguang;
Li, Jun;
Li, Runsheng;
Heng, Heng;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Delineation of IS Ecp1 and IS 26 -Mediated Plasmid Fusion Processes by MinION Single-Molecule Long-Read Sequencing.

Published in:

Frontiers in Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fmicb.2021.796715

By:

Chen, Kaichao;
Xie, Miaomiao;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

Article

Co-conjugation of Virulence Plasmid and KPC Plasmid in a Clinical Klebsiella pneumoniae Strain.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.739461

By:

Yang, Xuemei;
Dong, Ning;
Liu, Xiaoxuan;
Yang, Chen;
Ye, Lianwei;
Chan, Edward Wai-Chi;
Zhang, Rong;
Chen, Sheng

Publication type:

Article

The hypermucoviscosity of hypervirulent K. pneumoniae confers the ability to evade neutrophil-mediated phagocytosis.

Published in:

Virulence, 2021, v. 12, n. 1, p. 2050, doi. 10.1080/21505594.2021.1960101

By:

Xu, Qi;
Yang, Xuemei;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

The hypermucoviscosity of hypervirulent K. pneumoniae confers the ability to evade neutrophil-mediated phagocytosis.

Published in:

Virulence, 2021, v. 12, n. 1, p. 2050, doi. 10.1080/21505594.2021.1960101

By:

Qi Xu;
Xuemei Yang;
Wai Chi Chan, Edward;
Sheng Chen

Publication type:

Article

Proton motive force and antibiotic tolerance in bacteria.

Published in:

Microbial Biotechnology, 2024, v. 17, n. 11, p. 1, doi. 10.1111/1751-7915.70042

By:

Wan, Yingkun;
Zheng, Jiaqi;
Chan, Edward Wai‐Chi;
Chen, Sheng

Publication type:

Article

Identification and characterization of a conjugative blaVIM-1-bearing plasmid in Vibrio alginolyticus of food origin.

Published in:

2019

By:

Zheng, Zhiwei;
Ye, Lianwei;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

journal article

Selective and suppressive effects of antibiotics on donor and recipient bacterial strains in gut microbiota determine transmission efficiency of blaNDM-1-bearing plasmids.

Published in:

2019

By:

Ye, Lianwei;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

journal article

Characterization of the stability and dynamics of Tn6330 in an Escherichia coli strain by nanopore long reads.

Published in:

2019

By:

Li, Ruichao;
Chen, Kaichao;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

journal article

Carriage of blaKPC-2 by a virulence plasmid in hypervirulent Klebsiella pneumoniae.

Published in:

2018

By:

Dong, Ning;
Lin, Dachuan;
Chan, Edward Wai-Chi;
Chen, Sheng;
Zhang, Rong

Publication type:

journal article

Resolution of dynamic MDR structures among the plasmidome of Salmonella using MinION single-molecule, long-read sequencing.

Published in:

2018

By:

Li, Ruichao;
Chen, Kaichao;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

journal article

Deciphering mechanisms of blaNDM gene transmission between human and animals: a genomics study of bacterial isolates from various sources in China, 2015 to 2017.

Published in:

Eurosurveillance (15607917), 2023, v. 28, n. 37, p. 24, doi. 10.2807/1560-7917.ES.2023.28.37.2200925

By:

Kaichao Chen;
Miaomiao Xie;
Ning Dong;
Wai Chi Chan, Edward;
Rong Zhang;
Sheng Chen

Publication type:

Article

Intercontinental spread and clonal expansion of ColRNA1 plasmid-bearing Salmonella Corvallis ST1541 strains: a genomic epidemiological study.

Published in:

One Health Advances, 2023, v. 1, n. 1, p. 1, doi. 10.1186/s44280-023-00017-9

By:

Chen, Kaichao;
Xie, Miaomiao;
Wang, Han;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

Article

Imidazole Type Antifungal Drugs Are Effective Colistin Adjuvants That Resensitize Colistin‐Resistant Enterobacteriaceae.

Published in:

Advanced Therapeutics, 2020, v. 3, n. 12, p. 1, doi. 10.1002/adtp.202000182

By:

Xu, Chen;
Chen, Kaichao;
Chan, Kin Fai;
Chan, Edward Wai Chi;
Guo, Xuyun;
Chow, Hoi Yee;
Zhao, Guangming;
Zeng, Ping;
Wang, Miaomiao;
Zhu, Ye;
Li, Xuechen;
Wong, Kwok‐Yin;
Chen*, Sheng

Publication type:

Article

Imidazole Type Antifungal Drugs Are Effective Colistin Adjuvants That Resensitize Colistin‐Resistant Enterobacteriaceae.

Published in:

Advanced Therapeutics, 2020, v. 3, n. 9, p. 1, doi. 10.1002/adtp.202000084

By:

Xu, Chen;
Chen, Kaichao;
Chan, Kin Fai;
Chan, Edward Wai Chi;
Guo, Xuyun;
Chow, Hoi Yee;
Zhao, Guangming;
Zeng, Ping;
Wang, Miaomiao;
Zhu, Ye;
Li, Xuechen;
Wong, Kwok‐Yin;
Chen, Sheng

Publication type:

Article

Transmission of Chromosomal MDR DNA Fragment Encoding Ciprofloxacin Resistance by a Conjugative Helper Plasmid in Salmonella.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.556227

By:

Yang, Chen;
Chen, Kaichao;
Chan, Edward Wai-Chi;
Yao, Wen;
Chen, Sheng

Publication type:

Article

Contribution of biofilm formation genetic locus, pgaABCD, to antibiotic resistance development in gut microbiome.

Published in:

Gut Microbes, 2021, v. 13, n. 1, p. 1, doi. 10.1080/19490976.2020.1842992

By:

Lin, Dachuan;
Chen, Kaichao;
Guo, Jiubiao;
Ye, Lianwei;
Li, Ruichao;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance.

Published in:

Scientific Reports, 2016, p. 38793, doi. 10.1038/srep38793

By:

Hu, Menglong;
Guo, Jiubiao;
Cheng, Qipeng;
Yang, Zhiqiang;
Chan, Edward Wai Chi;
Chen, Sheng;
Hao, Quan

Publication type:

Article

Comparative genetic characterization of Enteroaggregative Escherichia coli strains recovered from clinical and non-clinical settings.

Published in:

Scientific Reports, 2016, p. 24321, doi. 10.1038/srep24321

By:

Zhang, Rong;
Gu, Dan-xia;
Huang, Yong-lu;
Chan, Edward Wai-Chi;
Chen, Gong-Xiang;
Chen, Sheng

Publication type:

Article

Mechanism of substrate recognition by the novel Botulinum Neurotoxin subtype F5.

Published in:

Scientific Reports, 2016, p. 19875, doi. 10.1038/srep19875

By:

Guo, Jiubiao;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Increasing prevalence of ciprofloxacin-resistant food-borne Salmonella strains harboring multiple PMQR elements but not target gene mutations.

Published in:

Scientific Reports, 2015, p. 1, doi. 10.1038/srep14754

By:

Dachuan Lin;
Kaichao Chen;
Wai-Chi Chan, Edward;
Sheng Chen

Publication type:

Article

Over-Expression of IS Aba1 -Linked Intrinsic and Exogenously Acquired OXA Type Carbapenem-Hydrolyzing-Class D-ß-Lactamase-Encoding Genes Is Key Mechanism Underlying Carbapenem Resistance in Acinetobacter baumannii.

Published in:

Frontiers in Microbiology, 2019, v. 10, p. 1, doi. 10.3389/fmicb.2019.02809

By:

Wong, Marcus Ho-yin;
Chan, Bill Kwan-wai;
Chan, Edward Wai-chi;
Chen, Sheng

Publication type:

Article

Genetic Characterization of bla <sub>CTX–M–55</sub> -Bearing Plasmids Harbored by Food-Borne Cephalosporin-Resistant Vibrio parahaemolyticus Strains in China.

Published in:

Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.01338

By:

Zheng, Zhiwei;
Li, Ruichao;
Ye, Lianwei;
Wai-chi Chan, Edward;
Xia, Xiaodong;
Chen, Sheng

Publication type:

Article

Increased prevalence of Escherichia coli strains from food carrying bla<sub>NDM</sub> and mcr-1-bearing plasmids that structurally resemble those of clinical strains, China, 2015 to 2017.

Published in:

Eurosurveillance (15607917), 2019, v. 24, n. 13, p. 27, doi. 10.2807/1560-7917.ES.2019.24.13.1800113

By:

Xiaobo Liu;
Shu Geng;
Wai-Chi Chan, Edward;
Sheng Chen

Publication type:

Article

Widespread distribution of mcr-1-bearing bacteria in the ecosystem, 2015 to 2016.

Published in:

Eurosurveillance (15607917), 2017, v. 22, n. 39, p. 32, doi. 10.2807/1560-7917.ES.2017.22.39.17-00206

By:

Kaichao Chen;
Wai-Chi Chan, Edward;
Miaomiao Xie;
Liangwei Ye;
Ning Dong;
Sheng Chen

Publication type:

Article

Genomic insights into the emergence and spread of NDM-1-producing Vibrio spp. isolates in China.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 3039, doi. 10.1093/jac/dkac276

By:

Zheng, Zhiwei;
Xu, Yating;
Ye, Lianwei;
Chan, Edward Wai Chi;
Chen, Sheng

Publication type:

Article

Econazole as adjuvant to conventional antibiotics is able to eradicate starvation-induced tolerant bacteria by causing proton motive force dissipation.

Published in:

2022

By:

Wang, Miaomiao;
Chan, Edward Wai Chi;
Xu, Chen;
Chen, Kaichao;
Yang, Chen;
Chen, Sheng

Publication type:

journal article

Emergence of an Empedobacter falsenii strain harbouring a tet(X)-variant-bearing novel plasmid conferring resistance to tigecycline.

Published in:

2020

By:

Zeng, Yu;
Dong, Ning;
Zhang, Rong;
Liu, Congcong;
Sun, Qiaoling;
Lu, Jiayue;
Shu, Lingbin;
Cheng, Qipeng;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

journal article

A Novel PCR-Based Approach for Accurate Identification of Vibrio parahaemolyticus.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.00044

By:

Ruichao Li;
Jiachi Chiou;
Wai-Chi Chan, Edward;
Sheng Chen;
Canizalez-Roman, Adrian;
Learn-Han Lee

Publication type:

Article

Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X).

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18475-9

By:

Zhang, Rong;
Dong, Ning;
Shen, Zhangqi;
Zeng, Yu;
Lu, Jiauyue;
Liu, Congcong;
Zhou, Hongwei;
Hu, Yanyan;
Sun, Qiaoling;
Cheng, Qipeng;
Shu, Lingbing;
Cai, Jiachang;
Chan, Edward Wai-Chi;
Chen, Gongxiang;
Chen, Sheng

Publication type:

Article

Myeloid-derived suppressor cell inhibits T-cell-based defense against Klebsiella pneumoniae infection via IDO1 production.

Published in:

PLoS Pathogens, 2025, v. 21, n. 3, p. 1, doi. 10.1371/journal.ppat.1012979

By:

Xu, Qi;
Liu, Xiaoxuan;
Heng, Heng;
Wang, Han;
Chen, Kaichao;
Chan, Edward Wai-Chi;
Yang, Guan;
Chen, Sheng

Publication type:

Article

Molecular mechanisms underlying the high mortality of hypervirulent Klebsiella pneumoniae and its effective therapy development.

Published in:

2023

By:

Xu, Qi;
Xie, Miaomiao;
Liu, Xiaoxuan;
Heng, Heng;
Wang, Han;
Yang, Chen;
Chan, Edward Wai-Chi;
Zhang, Rong;
Yang, Guan;
Chen, Sheng

Publication type:

Letter

Structural and Functional Characterization of OXA-48: Insight into Mechanism and Structural Basis of Substrate Recognition and Specificity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11480, doi. 10.3390/ijms222111480

By:

Chiou, Jiachi;
Cheng, Qipeng;
Shum, Perry Tim-fat;
Wong, Marcus Ho-yin;
Chan, Edward Wai-chi;
Chen, Sheng

Publication type:

Article

Clinical use of tigecycline may contribute to the widespread dissemination of carbapenem-resistant hypervirulent Klebsiella pneumoniae strains.

Published in:

Emerging Microbes & Infections, 2024, v. 13, n. 1, p. 1, doi. 10.1080/22221751.2024.2306957

By:

Miaomiao Xie;
Lianwei Ye;
Kaichao Chen;
Qi Xu;
Chen Yang;
Xiangnan Chen;
Wai-Chi Chan, Edward;
Fuyong Li;
Sheng Chen

Publication type:

Article

Epidemiological and genetic characteristics of clinical carbapenem-resistant Acinetobacter baumannii strains collected countrywide from hospital intensive care units (ICUs) in China.

Published in:

Emerging Microbes & Infections, 2022, v. 11, n. 1, p. 1730, doi. 10.1080/22221751.2022.2093134

By:

Liu, Congcong;
Chen, Kaichao;
Wu, Yuchen;
Huang, Ling;
Fang, Yinfei;
Lu, Jiayue;
Zeng, Yu;
Xie, Miaomiao;
Chan, Edward Wai Chi;
Chen, Sheng;
Zhang, Rong

Publication type:

Article

Identification and genetic characterization of two conjugative plasmids that confer azithromycin resistance in Salmonella.

Published in:

Emerging Microbes & Infections, 2022, v. 11, n. 1, p. 1049, doi. 10.1080/22221751.2022.2058420

By:

Xie, Miaomiao;
Chen, Kaichao;
Chan, Edward Wai-chi;
Chen, Sheng

Publication type:

Article

Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.

Published in:

Emerging Microbes & Infections, 2022, v. 11, n. 1, p. 841, doi. 10.1080/22221751.2022.2049458

By:

Yang, Xuemei;
Sun, Qiaoling;
Li, Jiaping;
Jiang, Yu;
Li, Yi;
Lin, Jianping;
Chen, Kaichao;
Chan, Edward Wai-Chi;
Zhang, Rong;
Chen, Sheng

Publication type:

Article

Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries.

Published in:

Emerging Microbes & Infections, 2020, v. 9, n. 1, p. 1287, doi. 10.1080/22221751.2020.1773745

By:

Yang, Xuemei;
Dong, Ning;
Chan, Edward Wai-Chi;
Chen, Sheng

Publication type:

Article