Found: 155

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  • CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals.

    Published in:
    Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01142-0
    By:
    • Simrén, Joel;
    • Brum, Wagner S.;
    • Ashton, Nicholas J.;
    • Benedet, Andrea L.;
    • Karikari, Thomas K.;
    • Kvartsberg, Hlin;
    • Sjons, Emma;
    • Lussier, Firoza Z.;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Hopewell, Robert;
    • Pallen, Vanessa;
    • Ye, Keqiang;
    • Pascoal, Tharick A.;
    • Zetterberg, Henrik;
    • Rosa-Neto, Pedro;
    • Blennow, Kaj
    Publication type:
    Article

  • Quantification of SNAP-25 with mass spectrometry and Simoa: a method comparison in Alzheimer's disease.

    Published in:
    Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01021-8
    By:
    • Nilsson, Johanna;
    • Ashton, Nicholas J.;
    • Benedet, Andrea L.;
    • Montoliu-Gaya, Laia;
    • Gobom, Johan;
    • Pascoal, Tharick A.;
    • Chamoun, Mira;
    • Portelius, Erik;
    • Jeromin, Andreas;
    • Mendes, Muriel;
    • Zetterberg, Henrik;
    • Rosa-Neto, Pedro;
    • Brinkmalm, Ann;
    • Blennow, Kaj
    Publication type:
    Article

  • Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer's disease.

    Published in:
    Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00802-x
    By:
    • Tissot, Cécile;
    • L. Benedet, Andréa;
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Lussier, Firoza Z.;
    • Saha-Chaudhuri, Paramita;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Mathotaarachchi, Sulantha S.;
    • Bezgin, Gleb;
    • Wang, Yi-Ting;
    • Fernandez Arias, Jaime;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K.;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • De Villers-Sidani, Etienne;
    • Huot, Philippe
    Publication type:
    Article

  • Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer's disease.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 659, p. 1, doi. 10.1126/scitranslmed.abc8693
    By:
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Savard, Mélissa;
    • Mathotaarachchi, Sulantha;
    • Benedet, Andréa L.;
    • Chamoun, Mira;
    • Tissot, Cécile;
    • Lussier, Firoza Z.;
    • Rahmouni, Nesrine;
    • Stevenson, Jenna;
    • Qureshi, Muhammad Naveed Iqbal;
    • Kang, Min Su;
    • Thomas, Émilie;
    • Vitali, Paolo;
    • Soucy, Jean-Paul;
    • Massarweh, Gassan;
    • Saha-Chaudhuri, Paramita;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid.

    Published in:
    Clinical Chemistry & Laboratory Medicine, 2022, v. 60, n. 2, p. 207, doi. 10.1515/cclm-2021-0651
    By:
    • Gobom, Johan;
    • Parnetti, Lucilla;
    • Rosa-Neto, Pedro;
    • Vyhnalek, Martin;
    • Gauthier, Serge;
    • Cataldi, Samuela;
    • Lerch, Ondrej;
    • Laczo, Jan;
    • Cechova, Katerina;
    • Clarin, Marcus;
    • Benet, Andrea L.;
    • Pascoal, Tharick A.;
    • Rahmouni, Neserine;
    • Vandijck, Manu;
    • Huyck, Else;
    • Le Bastard, Nathalie;
    • Stevenson, Jenna;
    • Chamoun, Mira;
    • Alcolea, Daniel;
    • Lleó, Alberto
    Publication type:
    Article

  • Plasma pTau‐217 and N‐terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid‐β positive individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1166, doi. 10.1002/alz.13528
    By:
    • Woo, Marcel S.;
    • Tissot, Cécile;
    • Lantero‐Rodriguez, Juan;
    • Snellman, Anniina;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Macedo, Arthur C.;
    • Servaes, Stijn;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Hosseini, Seyyed Ali;
    • Chamoun, Mira;
    • Lussier, Firoza Z.;
    • Benedet, Andrea L.;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K.;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth C.;
    • Stevenson, Jenna;
    • Mayer, Christina
    Publication type:
    Article

  • Amyloid‐dependent and amyloid‐independent effects of Tau in individuals without dementia.

    Published in:
    Annals of Clinical & Translational Neurology, 2021, v. 8, n. 10, p. 2083, doi. 10.1002/acn3.51457
    By:
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Sefranek, Marcus;
    • Mathotaarachchi, Sulantha;
    • Benedet, Andrea L.;
    • Chamoun, Mira;
    • Lussier, Firoza Z.;
    • Tissot, Cécile;
    • Bellaver, Bruna;
    • Lukasewicz, Pamela S.;
    • Zimmer, Eduardo R.;
    • Saha‐Chaudhuri, Paramita;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Author Correction: [<sup>11</sup>C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.

    Published in:
    2022
    By:
    • Pascoal, Tharick A.;
    • Chamoun, Mira;
    • Lax, Elad;
    • Wey, Hsiao-Ying;
    • Shin, Monica;
    • Ng, Kok Pin;
    • Kang, Min Su;
    • Mathotaarachchi, Sulantha;
    • Benedet, Andrea L.;
    • Therriault, Joseph;
    • Lussier, Firoza Z.;
    • Schroeder, Frederick A.;
    • DuBois, Jonathan M.;
    • Hightower, Baileigh G.;
    • Gilbert, Tonya M.;
    • Zürcher, Nicole R.;
    • Wang, Changning;
    • Hopewell, Robert;
    • Chakravarty, Mallar;
    • Savard, Melissa
    Publication type:
    Correction Notice

  • [<sup>11</sup>C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30653-5
    By:
    • Pascoal, Tharick A.;
    • Chamoun, Mira;
    • Lax, Elad;
    • Wey, Hsiao-Ying;
    • Shin, Monica;
    • Ng, Kok Pin;
    • Kang, Min Su;
    • Mathotaarachchi, Sulantha;
    • Benedet, Andrea L.;
    • Therriault, Joseph;
    • Lussier, Firoza Z.;
    • Schroeder, Frederick A.;
    • DuBois, Jonathan M.;
    • Hightower, Baileigh G.;
    • Gilbert, Tonya M.;
    • Zürcher, Nicole R.;
    • Wang, Changning;
    • Hopewell, Robert;
    • Chakravarty, Mallar;
    • Savard, Melissa
    Publication type:
    Article

  • Cholinergic Potentiation of Restoration of Visual Function after Optic Nerve Damage in Rats.

    Published in:
    Neural Plasticity, 2017, p. 1, doi. 10.1155/2017/6928489
    By:
    • Chamoun, Mira;
    • Sergeeva, Elena G.;
    • Henrich-Noack, Petra;
    • Jia, Shaobo;
    • Grigartzik, Lisa;
    • Ma, Jing;
    • You, Qing;
    • Huppé-Gourgues, Frédéric;
    • Sabel, Bernhard A.;
    • Vaucher, Elvire
    Publication type:
    Article

  • Normative Values of Neuromelanin‐Sensitive MRI Signal in Older Adults Obtained Using a Turbo Spin Echo Sequence.

    Published in:
    Journal of Magnetic Resonance Imaging, 2023, v. 58, n. 1, p. 294, doi. 10.1002/jmri.28530
    By:
    • Al Haddad, Rami;
    • Chamoun, Mira;
    • Tardif, Christine L.;
    • Guimond, Synthia;
    • Horga, Guillermo;
    • Rosa‐Neto, Pedro;
    • Cassidy, Clifford M.
    Publication type:
    Article

  • Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults.

    Published in:
    Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00022
    By:
    • Sheynin, Yasha;
    • Chamoun, Mira;
    • Baldwin, Alex S.;
    • Rosa-Neto, Pedro;
    • Hess, Robert F.;
    • Vaucher, Elvire
    Publication type:
    Article

  • Neuroinflammation Exacerbates Irritability and Agitation in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080138
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078423
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079764
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079681
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080098
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • Late‐life hypertension acts together with amyloid‐β pathology to promote early cognitive decline.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079952
    By:
    • Da Ros, Lucas Uglione;
    • Ferrari‐Souza, João Pedro;
    • Bastiani, Marco Antônio De;
    • Hauschild, Lucas Augusto;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andrea Lessa;
    • Pascoal, Tharick A.;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Sex impacts the association of plasma Glial Fibrillary Acidic Protein with neurodegeneration in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076402
    By:
    • Abbas, Sarah;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Ferrari‐Souza, João Pedro;
    • Lussier, Firoza Z;
    • Zalzale, Hussein;
    • Lemaire, Peter Charles;
    • Soares, Carolina;
    • Rohden, Francieli;
    • Aguzzoli, Cristiano Schaffer;
    • Cabrera, Arlec;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Stevenson, Jenna
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082041
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Neuroinflammation Exacerbates Irritability and Agitation in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081973
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081969
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081933
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081925
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • Plasma and CSF concentrations of N‐terminal tau fragments associate with in vivo neurofibrillary tangle burden.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5343, doi. 10.1002/alz.13119
    By:
    • Lantero‐Rodriguez, Juan;
    • Tissot, Cécile;
    • Snellman, Anniina;
    • Servaes, Stijn;
    • Benedet, Andrea L.;
    • Rahmouni, Nesrine;
    • Montoliu‐Gaya, Laia;
    • Therriault, Joseph;
    • Brum, Wagner S.;
    • Stevenson, Jenna;
    • Lussier, Firoza Z.;
    • Bezgin, Gleb;
    • Macedo, Arthur C.;
    • Chamoun, Mira;
    • Mathotaarachi, Sulantha S.;
    • Pascoal, Tharick A.;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Neto, Pedro Rosa;
    • Blennow, Kaj
    Publication type:
    Article

  • Blood‐brain barrier integrity impacts the use of plasma amyloid‐β as a proxy of brain amyloid‐β pathology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 9, p. 3815, doi. 10.1002/alz.13014
    By:
    • Bellaver, Bruna;
    • Puig‐Pijoan, Albert;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas T.;
    • Lussier, Firoza Z.;
    • Ferreira, Pamela C. L.;
    • Tissot, Cécile;
    • Povala, Guilherme;
    • Therriault, Joseph;
    • Benedet, Andréa L.;
    • Ashton, Nicholas J.;
    • Servaes, Stijn;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Vermeiren, Marie;
    • Macedo, Arthur C.;
    • Fernández‐Lebrero, Aida;
    • García‐Escobar, Greta;
    • Navalpotro‐Gómez, Irene
    Publication type:
    Article

  • IC‐P‐064: THE IMPACT OF TSPO RS6971 POLYMORPHISM IN A CANADIAN NEUROIMAGING STUDY OF NEUROINFLAMMATION.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P58, doi. 10.1016/j.jalz.2018.06.2129
    By:
    • Benedet, Andrea Lessa;
    • Pascoal, Tharick A.;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Schoemaker, Dorothee;
    • Mathotaarachchi, Sulantha;
    • Kang, Min-Su;
    • Therriault, Joseph;
    • Collins, Louis;
    • Gauthier, Serge;
    • Poirier, Judes;
    • Labbe, Aurelie;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • IC‐P‐063: THE EFFECT OF PROTON PUMP INHIBITORS AND CYP2C19 ON AMYLOID PATHOLOGY.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P58, doi. 10.1016/j.jalz.2018.06.2128
    By:
    • Benedet, Andrea Lessa;
    • Mathotaarachchi, Sulantha;
    • Pascoal, Tharick A.;
    • Medina, Yasser Iturria;
    • Savard, Melissa;
    • Therriault, Joseph;
    • Kang, Min-Su;
    • Chamoun, Mira;
    • Gauthier, Serge;
    • Evans, Alan C.;
    • Labbe, Aurelie;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • IC‐P‐054: AMYLOID AND MICROGLIAL ACTIVATION SYNERGY LEADS TO HYPOMETABOLISM IN THE AD BRAIN: MICROPET LONGITUDINAL STUDY.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P51, doi. 10.1016/j.jalz.2018.06.2119
    By:
    • Kang, Min Su;
    • Shin, Monica;
    • Mathotaarachchi, Sulantha;
    • Pascoal, Tharick A.;
    • Parent, Maxime J.;
    • Benedet, Andrea Lessa;
    • Therriault, Joseph;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Thomas, Emilie;
    • Aliaga, Antonio;
    • Massarweh, Gassan;
    • Soucy, Jean-Paul;
    • Gauthier, Serge;
    • Cuello, A. Claudio;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • IC‐P‐055: REGIONAL PATTERNS OF TAU DEPOSITION DRIVEN BY LOCAL AMYLOID ACCUMULATION RECAPITULATE BRAAK STAGES IN AD.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P52, doi. 10.1016/j.jalz.2018.06.2120
    By:
    • Kang, Min Su;
    • Mathotaarachchi, Sulantha;
    • Pascoal, Tharick A.;
    • Benedet, Andrea Lessa;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Therriault, Joseph;
    • Shin, Monica;
    • Thomas, Emilie;
    • Soucy, Jean-Paul;
    • Massarweh, Gassan;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • IC‐P‐022: LATERAL TEMPORAL AMYLOID LOAD PREDICTS PROGRESSION TO ALZHEIMER'S DEMENTIA.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P28, doi. 10.1016/j.jalz.2018.06.2086
    By:
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Mathotaarachchi, Sulantha;
    • Kang, Min Su;
    • Shin, Monica;
    • Chamoun, Mira;
    • Benedet, Andrea Lessa;
    • Savard, Melissa;
    • Thomas, Emilie;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • IC‐P‐023: UNBIASED ASSESSMENT OF GLOBAL AMYLOID LOAD AS DETERMINED BY VOXEL‐WISE RECEIVER OPERATING CHARACTERISTIC ANALYSIS.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P29, doi. 10.1016/j.jalz.2018.06.2087
    By:
    • Therriault, Joseph;
    • Pascoal, Tharick A.;
    • Mathotaarachchi, Sulantha;
    • Kang, Min Su;
    • Shin, Monica;
    • Chamoun, Mira;
    • Savard, Melissa;
    • Benedet, Andrea Lessa;
    • Massarweh, Gassan;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro;
    • Thomas, Emilie
    Publication type:
    Article

  • IC‐04‐05: IMAGING EPIGENETICS IN THE HUMAN BRAIN WITH THE NOVEL [<sup>11</sup>C]MARTINOSTAT PET IN PRECLINICAL AD, MCI, AD, AND FRONTOTEMPORAL DEMENTIA INDIVIDUALS.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P9, doi. 10.1016/j.jalz.2018.06.2053
    By:
    • Pascoal, Tharick A.;
    • Chamoun, Mira;
    • Shin, Monica;
    • Benedet, Andrea Lessa;
    • Mathotaarachchi, Sulantha;
    • Kang, Min Su;
    • Therriault, Joseph;
    • Savard, Melissa;
    • Thomas, Emilie;
    • Massarweh, Gassan;
    • Soucy, Jean-Paul;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • Association between tau uptake and verbal fluency converge in language centers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.068006
    By:
    • Stevenson, Alyssa;
    • Rahmouni, Nesrine;
    • Therriault, Joseph;
    • Stevenson, Jenna;
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Bezgin, Gleb;
    • Chamoun, Mira;
    • Pascoal, Tharick A;
    • Gauthier, Serge;
    • Benedet, Andréa Lessa;
    • Vitali, Paolo;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Adapting to reality: Effect of Online Assessments as Compared to In‐Person Assessments.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067999
    By:
    • Pallen, Vanessa;
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Stevenson, Jenna;
    • Stevenson, Alyssa;
    • Poltronetti, Nina Margherita;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Kunach, Peter;
    • Pascoal, Tharick;
    • Servaes, Stijn;
    • Savard, Melissa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Verbal recognition declines in later Braak Stages compared to verbal delayed recall.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067152
    By:
    • Arias, Jaime Fernandez;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Pascoal, Tharick A;
    • Tissot, Cécile;
    • Wang, Yi‐Ting;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Kang, Min Su;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Poltronetti, Nina Margherita;
    • Kunach, Peter;
    • Ottoy, Julie;
    • Stevenson, Alyssa;
    • Mathotaarachchi, Sulantha;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Gauthier, Serge
    Publication type:
    Article

  • Mild behavioral impairment symptom severity predicts tau hyperphosphorylation assessed by plasma p‐tau181 across the Alzheimer's disease spectrum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.060982
    By:
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Ismail, Zahinoor;
    • Pascoal, Tharick A;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • TRIAD multi‐dimensional biobank for biomarker discovery.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.067924
    By:
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Stevenson, Alyssa;
    • Pallen, Vanessa;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Bezgin, Gleb;
    • Pascoal, Tharick A;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Impact of meningeal and age‐related off‐target binding on longitudinal [<sup>18</sup>F]MK6240 quantification.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.066227
    By:
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Kunach, Peter;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Villemagne, Victor L;
    • Tudorascu, Dana L
    Publication type:
    Article

  • Comparison of plasma amyloid, tau, and astrocyte biomarkers to identify AD pathophysiology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065854
    By:
    • Ferreira, Pamela C.L.;
    • Tissot, Cécile;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Brum, Wagner S.;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Benedet, Andréa Lessa;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Tudorascu, Dana L;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Cohen, Ann D;
    • Zimmer, Eduardo R.;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik
    Publication type:
    Article

  • Apolipoprotein E ε4 associates with microglial activation in early Braak regions independently of amyloid‐β and tau.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065731
    By:
    • Ferrari‐Souza, João Pedro;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Leffa, Douglas Teixeira;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Brum, Wagner S.;
    • Benedet, Andréa Lessa;
    • Therriault, Joseph;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa;
    • Poltronetti, Nina Margherita;
    • Souza, Diogo O.;
    • Gauthier, Serge
    Publication type:
    Article

  • Tau phosphorylation is more closely associated with amyloid‐β plaques than with tau neurofibrillary tangles.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.064277
    By:
    • Vermeiren, Marie;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Pascoal, Tharick A;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Kunach, Peter;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Soucy, Jean‐Paul
    Publication type:
    Article

  • pTau heterogeneity as a measure for disease severity in incipient Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.063749
    By:
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Arias, Jaime Fernandez;
    • Benedet, Andréa Lessa;
    • Chamoun, Mira;
    • Pascoal, Tharick A;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Amyloid and tau pathologies associate with distinct aspects of the inflammatory cascade.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067639
    By:
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Ferreira, Pamela C.L.;
    • Ferrari‐Souza, João Pedro;
    • De Bastiani, Marco Antônio;
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Therriault, Joseph;
    • Benedet, Andréa Lessa;
    • Servaes, Stijn;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Gauthier, Serge;
    • Schöll, Michael;
    • Ashton, Nicholas J.;
    • Zimmer, Eduardo R;
    • Zetterberg, Henrik;
    • Karikari, Thomas K;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Situating tau pathology and neuroinflammation along the principal gradients of brain organisation in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.066680
    By:
    • Ottoy, Julie;
    • Kang, Min Su;
    • Yeh, Yi‐Hsuan;
    • de Wael, Reinder Vos;
    • Park, Bo‐yong;
    • Isen, Jonah;
    • Agopian, Mary;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Mathotaarachchi, Sulantha;
    • Stevenson, Jenna;
    • Chamoun, Mira;
    • Rahmouni, Nesrine;
    • Hopewell, Robert;
    • Massarweh, Gassan;
    • Soucy, Jean‐Paul;
    • Gauthier, Serge;
    • Bernhardt, Boris;
    • Black, Sandra E.;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Longitudinal changes in plasma p‐tau181 as a surrogate variable to populational interventions.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.066159
    By:
    • Ferreira, Pamela C.L.;
    • Ferrari‐Souza, João Pedro;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Tissot, Cécile;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Brum, Wagner S.;
    • Therriault, Joseph;
    • Chamoun, Mira;
    • Lussier, Firoza Z;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Soucy, Jean‐Paul;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Zimmer, Eduardo R.;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Impact of meningeal and age‐related off‐target binding on longitudinal [<sup>18</sup>F]MK6240 quantification.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.068139
    By:
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Kunach, Peter;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Villemagne, Victor L;
    • Tudorascu, Dana L
    Publication type:
    Article

  • Association between tau uptake and verbal fluency converge in language centers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.068093
    By:
    • Stevenson, Alyssa;
    • Rahmouni, Nesrine;
    • Therriault, Joseph;
    • Stevenson, Jenna;
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Bezgin, Gleb;
    • Chamoun, Mira;
    • Pascoal, Tharick A;
    • Gauthier, Serge;
    • Benedet, Andréa Lessa;
    • Vitali, Paolo;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • TRIAD multi‐dimensional biobank for biomarker discovery.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.067980
    By:
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Stevenson, Alyssa;
    • Pallen, Vanessa;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Bezgin, Gleb;
    • Pascoal, Tharick A;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Comparison of plasma amyloid, tau, and astrocyte biomarkers to identify AD pathophysiology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.067439
    By:
    • Ferreira, Pamela C.L.;
    • Tissot, Cécile;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Brum, Wagner S.;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Benedet, Andréa Lessa;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Tudorascu, Dana L;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Cohen, Ann D;
    • Zimmer, Eduardo R.;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik
    Publication type:
    Article