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Il-10 signaling reduces survival in mouse models of synucleinopathy.
- Published in:
- NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
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- Publication type:
- Article
Impact of APOE genotype on prion-type propagation of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01359-y
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- Publication type:
- Article
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00967-w
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- Publication type:
- Article
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5198, doi. 10.1002/alz.13868
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- Publication type:
- Article
Sex differences in functional network topological measures in the APP‐PS1 mouse model of amyloidosis.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074329
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- Publication type:
- Article
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 984, doi. 10.1002/alz.12254
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- Publication type:
- Article
A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 933, doi. 10.1002/alz.12318
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- Publication type:
- Article
Exploring the pathologic synergy between amyloid β and tau: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043477
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- Publication type:
- Article
Effect of soluble interleukin‐10 receptor expression in mouse models of Alzheimer's disease: Molecular and cell biology/neuroinflammation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041927
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- Publication type:
- Article
O4‐01‐05: COMPARATIVE PRIONOID AND STRAIN PROPERTIES OF TAU AND SYNUCLEIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1230, doi. 10.1016/j.jalz.2019.06.4744
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- Publication type:
- Article
P3‐091: MODELING TAUOPATHY USING AAV‐MEDIATED SOMATIC BRAIN TRANSGENESIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1100, doi. 10.1016/j.jalz.2018.06.1447
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- Publication type:
- Article
O3‐03‐01: MECHANISTIC AND DIRECTIONAL TRANSCRIPTIONAL REGULATORY NETWORKS IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1014, doi. 10.1016/j.jalz.2018.06.2782
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- Publication type:
- Article
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 3, p. 352, doi. 10.1016/j.jalz.2017.09.012
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- Publication type:
- Article
MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8175, doi. 10.3390/ijms23158175
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- Publication type:
- Article
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
- Published in:
- Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0469-0
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- Publication type:
- Article
TARGETING TAU AGGREGATION IN BRAIN SLICE CULTURE MODELS OF TAUOPATHIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1294, doi. 10.1016/j.jalz.2017.06.1959
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- Publication type:
- Article
FROM SYSTEMS LEVEL TRANSCRIPTOMICS TO NEW IMMUNE TARGETS FOR ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P215, doi. 10.1016/j.jalz.2016.06.383
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- Publication type:
- Article
IL-10 modifies disease progression and pathology in a mouse model of alpha synucleinopathy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P182, doi. 10.1016/j.jalz.2015.07.154
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- Publication type:
- Article
Modulating chemokine signaling in preclinical Alzheimer's disease models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P157, doi. 10.1016/j.jalz.2015.07.089
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- Publication type:
- Article
Towards a comprehensive analysis of the role of inflammatory mediators on Alzheimer's like pathology in pre-clinical mouse models
- Published in:
- 2011
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- Publication type:
- Abstract
AAV-mediated expression of anti-inflammatory cytokines IL-10 and IL-4 significantly exacerbate amyloid pathology in the brains of APP TgCRND8 mice
- Published in:
- 2010
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- Publication type:
- Abstract
P3-354: Role of IL-6–mediated chronic neuroinflammation on amyloid pathology
- Published in:
- 2008
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- Publication type:
- Abstract
P1-005: RAAV vectors to rapidly modify and model AD pathology in mice, rats, and guinea pigs
- Published in:
- 2006
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- Publication type:
- Abstract
P1-005: RAAV vectors to rapidly modify and model AD pathology in mice, rats, and guinea pigs
- Published in:
- 2006
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- Publication type:
- Abstract
Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067680
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- Publication type:
- Article
Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00911-y
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- Publication type:
- Article
Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.
- Published in:
- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0458-0
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- Publication type:
- Article
Diffusion magnetic resonance imaging-derived free water detects neurodegenerative pattern induced by interferon-γ.
- Published in:
- Brain Structure & Function, 2020, v. 225, n. 1, p. 427, doi. 10.1007/s00429-019-02017-1
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- Publication type:
- Article
Conditional Neuronal Simian Virus 40 T Antigen Expression Induces Alzheimer-Like Tau and Amyloid Pathology in Mice.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 11, p. 2969, doi. 10.1523/JNEUROSCI.0186-07.2007
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- Publication type:
- Article
Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy.
- Published in:
- Journal of Neuroinflammation, 2006, v. 3, p. 17, doi. 10.1186/1742-2094-3-17
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- Publication type:
- Article
Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.
- Published in:
- Life Science Alliance, 2021, v. 4, n. 7, p. 1, doi. 10.26508/lsa.202101108
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- Publication type:
- Article
Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 1, p. 53, doi. 10.1038/mt.2014.180
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- Publication type:
- Article
Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01664-0
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- Publication type:
- Article
Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01581-2
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- Publication type:
- Article
Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation.
- Published in:
- Neuropathology & Applied Neurobiology, 2022, v. 48, n. 2, p. 1, doi. 10.1111/nan.12779
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- Publication type:
- Article
Aberrant insulin signaling in Alzheimer's disease: current knowledge.
- Published in:
- Frontiers in Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnins.2015.00204
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- Publication type:
- Article
IFN-γ promotes τ phosphorylation without affecting mature tangles.
- Published in:
- FASEB Journal, 2015, v. 29, n. 10, p. 4384, doi. 10.1096/fj.15-275834
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- Publication type:
- Article
Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
- Published in:
- FASEB Journal, 2010, v. 24, n. 2, p. 548, doi. 10.1096/fj.09-141754
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- Publication type:
- Article
Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.
- Published in:
- Alzheimer's Research & Therapy, 2012, v. 4, n. 3, p. 1, doi. 10.1186/alzrt121
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- Publication type:
- Article
Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology.
- Published in:
- Journal of Neurochemistry, 2017, v. 140, n. 4, p. 662, doi. 10.1111/jnc.13743
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- Publication type:
- Article
Author Correction: IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis.
- Published in:
- 2021
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- Publication type:
- Correction Notice
IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77564-3
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- Publication type:
- Article
Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 19, p. 3255, doi. 10.1093/hmg/ddz151
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- Publication type:
- Article
Gut mycobiome dysbiosis after sepsis and trauma.
- Published in:
- Critical Care, 2024, v. 28, p. 1, doi. 10.1186/s13054-023-04780-4
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- Publication type:
- Article
Tau-Mediated Dysregulation of Neuroplasticity and Glial Plasticity.
- Published in:
- Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.00151
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- Publication type:
- Article
α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease.
- Published in:
- Acta Neuropathologica, 2019, v. 138, n. 1, p. 1, doi. 10.1007/s00401-019-01977-2
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- Publication type:
- Article
Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology.
- Published in:
- 2016
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- Publication type:
- Letter
Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission.
- Published in:
- 2015
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- Publication type:
- Letter
Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
- Published in:
- Acta Neuropathologica, 2013, v. 126, n. 1, p. 39, doi. 10.1007/s00401-013-1123-8
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- Publication type:
- Article
Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification.
- Published in:
- Nature Neuroscience, 2011, v. 14, n. 6, p. 694, doi. 10.1038/nn.2829
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- Publication type:
- Article