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Targeting of Metabotropic Glutamate Receptors for the Development of Novel Antidepressants.
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- Chronic Stress, 2019, v. 3, p. N.PAG, doi. 10.1177/2470547019837712
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Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents.
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- International Journal of Neuropsychopharmacology, 2022, v. 25, n. 2, p. 106, doi. 10.1093/ijnp/pyab062
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Vasopressin V<sub>1B</sub> Receptor Antagonists as Potential Antidepressants.
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- International Journal of Neuropsychopharmacology, 2021, v. 24, n. 6, p. 450, doi. 10.1093/ijnp/pyab013
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No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model.
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- International Journal of Neuropsychopharmacology, 2018, v. 21, n. 10, p. 932, doi. 10.1093/ijnp/pyy053
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Role of 5-HT<sub>1A</sub> Receptor Stimulation in the Medial Prefrontal Cortex in the Sustained Antidepressant Effects of Ketamine.
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- International Journal of Neuropsychopharmacology, 2018, v. 21, n. 4, p. 371, doi. 10.1093/ijnp/pyx116
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Is Metabolism of (R)-Ketamine Essential for the Antidepressant Effects?
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- International Journal of Neuropsychopharmacology, 2018, v. 21, n. 2, p. 154, doi. 10.1093/ijnp/pyx120
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Strategies for Utilizing Neuroimaging Biomarkers in CNS Drug Discovery and Development: CINP/JSNP Working Group Report.
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- International Journal of Neuropsychopharmacology, 2017, v. 20, n. 4, p. 285, doi. 10.1093/ijnp/pyw111
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Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine.
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- International Journal of Neuropsychopharmacology, 2017, v. 20, n. 3, p. 228, doi. 10.1093/ijnp/pyw089
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- Article
A selective, non-peptide CRF receptor 1 antagonist prevents sodium lactate-induced acute panic-like responses.
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- International Journal of Neuropsychopharmacology, 2011, v. 14, n. 3, p. 355, doi. 10.1017/S1461145710001355
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Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants.
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- Pharmaceuticals (14248247), 2015, v. 8, n. 3, p. 590, doi. 10.3390/ph8030590
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- Article
Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants.
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- Pharmaceuticals (14248247), 2015, v. 8, n. 3, p. 590, doi. 10.3390/ph8030590
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- Article
Role of Serotonergic System in the Antidepressant Actions of mGlu2/3 Receptor Antagonists: Similarity to Ketamine.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 6, p. 1270, doi. 10.3390/ijms20061270
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- Article
The atypical antipsychotic profile of NRA0045, a novel dopamine D<sub>4</sub> and 5-hydroxytryptamine<sub>2A</sub> receptor antagonist, in rats.
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- British Journal of Pharmacology, 1997, v. 121, n. 3, p. 515, doi. 10.1038/sj.bjp.0701164
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- Article
Safety and pharmacokinetic profiles of MGS0274 besylate (TS‐134), a novel metabotropic glutamate 2/3 receptor agonist prodrug, in healthy subjects.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 11, p. 2286, doi. 10.1111/bcp.14331
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mGlu2/3 receptor antagonists for depression: overview of underlying mechanisms and clinical development.
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- European Archives of Psychiatry & Clinical Neuroscience, 2023, v. 273, n. 7, p. 1451, doi. 10.1007/s00406-023-01561-6
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Melanin-Concentrating Hormone MCH1 Receptor Antagonists: A Potential New Approach to the Treatment of Depression and Anxiety Disorders.
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- CNS Drugs, 2006, v. 20, n. 10, p. 801, doi. 10.2165/00023210-200620100-00002
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- Article
Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with <sup>11</sup>C-labeled 20-HETE synthase-specific inhibitor.
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- Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 9, p. 1737, doi. 10.1038/jcbfm.2012.68
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- Article
Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission.
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- Psychopharmacology, 2011, v. 217, n. 3, p. 443, doi. 10.1007/s00213-011-2295-3
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On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039.
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- Psychopharmacology, 2010, v. 212, n. 4, p. 523, doi. 10.1007/s00213-010-1978-5
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d-Serine and a glycine transporter-1 inhibitor enhance social memory in rats.
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- Psychopharmacology, 2010, v. 209, n. 3, p. 263, doi. 10.1007/s00213-010-1794-y
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Effects of metabotropic glutamate 2/3 receptor antagonists in the stress-induced hyperthermia test in singly housed mice.
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- Psychopharmacology, 2007, v. 190, n. 2, p. 233, doi. 10.1007/s00213-006-0618-6
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An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats.
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- Psychopharmacology, 2006, v. 186, n. 4, p. 587, doi. 10.1007/s00213-006-0390-7
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High-Contrast PET Imaging of Vasopressin V<sub>1B</sub> Receptors with a Novel Radioligand, <sup>11</sup>C-TASP699.
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- Journal of Nuclear Medicine, 2017, v. 58, n. 10, p. 1652, doi. 10.2967/jnumed.116.188698
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Melanin‐concentrating hormone receptor 1 antagonists for the treatment of depression and anxiety.
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- Drug Development Research, 2005, v. 65, n. 4, p. 278, doi. 10.1002/ddr.20029
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Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model.
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- Psychopharmacology, 2018, v. 235, n. 11, p. 3177, doi. 10.1007/s00213-018-5017-2
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Efficacy of a glycine transporter 1 inhibitor TASP0315003 in animal models of cognitive dysfunction and negative symptoms of schizophrenia.
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- Psychopharmacology, 2015, v. 232, n. 15, p. 2849, doi. 10.1007/s00213-015-3920-3
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Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)-3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the novelty-suppressed feeding test
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- Psychopharmacology, 2014, v. 231, n. 11, p. 2291, doi. 10.1007/s00213-013-3378-0
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Polyamine transport, accumulation, and release in brain.
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- Journal of Neurochemistry, 2003, v. 84, n. 3, p. 610, doi. 10.1046/j.1471-4159.2003.01558.x
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The Role of the DRY Motif of Human MC4R for Receptor Activation.
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- Bioscience, Biotechnology & Biochemistry, 2004, v. 68, n. 6, p. 1369, doi. 10.1271/bbb.68.1369
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Is the History Repeated? Can (2R,6R)-Hydroxynorketamine be Another Antidepressant?
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- Journal of Experimental Neuroscience, 2018, v. 12, p. 1, doi. 10.1177/1179069518815445
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Role of carboxyl tail of the rat angiotensin II type 1A receptor in agonist-induced internalization of the receptor.
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- Kidney International, 1994, v. 46, n. 6, p. 1492, doi. 10.1038/ki.1994.427
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