Works by Cerchia, Carmen

Results: 21

Synthesis and in vitro cytotoxicity of benzoxazole‐based PPARα/γ antagonists in colorectal cancer cell lines.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 9, p. 1, doi. 10.1002/ardp.202400086

By:

Moreno‐Rodríguez, Nazaret;
Laghezza, Antonio;
Cerchia, Carmen;
Sokolova, Darina V.;
Spirina, Tatiana S.;
De Filippis, Barbara;
Romanelli, Virgilio;
Recio, Rocío;
Fernández, Inmaculada;
Loiodice, Fulvio;
Pokrovsky, Vadim S.;
Ammazzalorso, Alessandra;
Lavecchia, Antonio

Publication type:

Article

"Molecular Anatomy": a new multi-dimensional hierarchical scaffold analysis tool.

Published in:

Journal of Cheminformatics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13321-021-00526-y

By:

Manelfi, Candida;
Gemei, Marica;
Talarico, Carmine;
Cerchia, Carmen;
Fava, Anna;
Lunghini, Filippo;
Beccari, Andrea Rosario

Publication type:

Article

"DompeKeys": a set of novel substructure-based descriptors for efficient chemical space mapping, development and structural interpretation of machine learning models, and indexing of large databases.

Published in:

Journal of Cheminformatics, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13321-024-00813-4

By:

Manelfi, Candida;
Tazzari, Valerio;
Lunghini, Filippo;
Cerchia, Carmen;
Fava, Anna;
Pedretti, Alessandro;
Stouten, Pieter F. W.;
Vistoli, Giulio;
Beccari, Andrea Rosario

Publication type:

Article

A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 484, doi. 10.1002/cmdc.202000564

By:

Yasmin, Sabina;
Cerchia, Carmen;
Badavath, Vishnu Nayak;
Laghezza, Antonio;
Dal Piaz, Fabrizio;
Mondal, Susanta K.;
Atlı, Özlem;
Baysal, Merve;
Vadivelan, Sankaran;
Shankar, S.;
Siddique, Mohd Usman Mohd;
Pattnaik, Ashok Kumar;
Singh, Ravi Pratap;
Loiodice, Fulvio;
Jayaprakash, Venkatesan;
Lavecchia, Antonio

Publication type:

Article

Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes.

Published in:

ChemMedChem, 2019, v. 14, n. 8, p. 842, doi. 10.1002/cmdc.201900028

By:

Ettari, Roberta;
Cerchia, Carmen;
Maiorana, Santina;
Guccione, Manuela;
Novellino, Ettore;
Bitto, Alessandra;
Grasso, Silvana;
Lavecchia, Antonio;
Zappalà, Maria

Publication type:

Article

Novel Reversible Inhibitors of Xanthine Oxidase Targeting the Active Site of the Enzyme.

Published in:

Antioxidants, 2023, v. 12, n. 4, p. 825, doi. 10.3390/antiox12040825

By:

Rullo, Rosario;
Cerchia, Carmen;
Nasso, Rosarita;
Romanelli, Virgilio;
Vendittis, Emmanuele De;
Masullo, Mariorosario;
Lavecchia, Antonio

Publication type:

Article

In Silico Identification of Novel Inhibitors Targeting the Homodimeric Interface of Superoxide Dismutase from the Dental Pathogen Streptococcus mutans.

Published in:

Antioxidants, 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/antiox11040785

By:

Cerchia, Carmen;
Roscetto, Emanuela;
Nasso, Rosarita;
Catania, Maria Rosaria;
De Vendittis, Emmanuele;
Lavecchia, Antonio;
Masullo, Mariorosario;
Rullo, Rosario

Publication type:

Article

Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1801, doi. 10.1002/cmdc.201402075

By:

Scarbaci, Kety;
Troiano, Valeria;
Ettari, Roberta;
Pinto, Andrea;
Micale, Nicola;
Di Giovanni, Carmen;
Cerchia, Carmen;
Schirmeister, Tanja;
Novellino, Ettore;
Lavecchia, Antonio;
Zappalà, Maria;
Grasso, Silvana

Publication type:

Article

Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41765-2

By:

Sabatino, Lina;
Ziccardi, Pamela;
Cerchia, Carmen;
Muccillo, Livio;
Piemontese, Luca;
Loiodice, Fulvio;
Colantuoni, Vittorio;
Lupo, Angelo;
Lavecchia, Antonio

Publication type:

Article

Editorial: Recent trends in anti-cancer drug discovery by in silico methods.

Published in:

Frontiers in Drug Discovery, 2024, p. 1, doi. 10.3389/fddsv.2024.1420267

By:

Cerchia, Carmen;
Basurto, Jose Correa;
Lupo, Angelo;
Lavecchia, Antonio

Publication type:

Article

Deep generative models in the quest for anticancer drugs: ways forward.

Published in:

Frontiers in Drug Discovery, 2024, p. 1, doi. 10.3389/fddsv.2024.1362956

By:

Romanelli, Virgilio;
Cerchia, Carmen;
Lavecchia, Antonio

Publication type:

Article

Impairment of Nucleolin Activity and Phosphorylation by a Trachylobane Diterpene from Psiadia punctulata in Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11390, doi. 10.3390/ijms231911390

By:

Bellone, Maria Laura;
Fiengo, Lorenzo;
Cerchia, Carmen;
Cotugno, Roberta;
Bader, Ammar;
Lavecchia, Antonio;
De Tommasi, Nunziatina;
Piaz, Fabrizio Dal

Publication type:

Article

Altered Local Interactions and Long-Range Communications in UK Variant (B.1.1.7) Spike Glycoprotein.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5464, doi. 10.3390/ijms22115464

By:

Borocci, Stefano;
Cerchia, Carmen;
Grottesi, Alessandro;
Sanna, Nico;
Prandi, Ingrid Guarnetti;
Abid, Nabil;
Beccari, Andrea R.;
Chillemi, Giovanni;
Talarico, Carmine

Publication type:

Article

Binding Mode Exploration of B1 Receptor Antagonists' by the Use of Molecular Dynamics and Docking Simulation—How Different Target Engagement Can Determine Different Biological Effects.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7677, doi. 10.3390/ijms21207677

By:

Gemei, Marica;
Talarico, Carmine;
Brandolini, Laura;
Manelfi, Candida;
Za, Lorena;
Bovolenta, Silvia;
Liberati, Chiara;
Del Vecchio, Luigi;
Russo, Roberto;
Cerchia, Carmen;
Allegretti, Marcello;
Beccari, Andrea Rosario

Publication type:

Article

SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5707, doi. 10.3390/ijms21165707

By:

Cannalire, Rolando;
Stefanelli, Irina;
Cerchia, Carmen;
Beccari, Andrea R.;
Pelliccia, Sveva;
Summa, Vincenzo

Publication type:

Article

Computational Studies of SARS-CoV-2 3CLpro: Insights from MD Simulations.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5346, doi. 10.3390/ijms21155346

By:

Grottesi, Alessandro;
Bešker, Neva;
Emerson, Andrew;
Manelfi, Candida;
Beccari, Andrea R.;
Frigerio, Francesco;
Lindahl, Erik;
Cerchia, Carmen;
Talarico, Carmine

Publication type:

Article

APP Maturation and Intracellular Localization Are Controlled by a Specific Inhibitor of 37/67 kDa Laminin-1 Receptor in Neuronal Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1738, doi. 10.3390/ijms21051738

By:

Bhattacharya, Antaripa;
Limone, Adriana;
Napolitano, Filomena;
Cerchia, Carmen;
Parisi, Silvia;
Minopoli, Giuseppina;
Montuori, Nunzia;
Lavecchia, Antonio;
Sarnataro, Daniela

Publication type:

Article

A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability.

Published in:

Scientific Reports, 2017, p. 41273, doi. 10.1038/srep41273

By:

Vasaturo, Michele;
Fiengo, Lorenzo;
De Tommasi, Nunziatina;
Sabatino, Lina;
Ziccardi, Pamela;
Colantuoni, Vittorio;
Bruno, Maurizio;
Cerchia, Carmen;
Novellino, Ettore;
Lupo, Angelo;
Lavecchia, Antonio;
Piaz, Fabrizio Dal

Publication type:

Article

Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode.

Published in:

Scientific Reports, 2016, p. 34792, doi. 10.1038/srep34792

By:

Capelli, Davide;
Cerchia, Carmen;
Montanari, Roberta;
Loiodice, Fulvio;
Tortorella, Paolo;
Laghezza, Antonio;
Cervoni, Laura;
Pochetti, Giorgio;
Lavecchia, Antonio

Publication type:

Article

A sulfonimide derivative of bezafibrate as a dual inhibitor of cyclooxygenase-2 and PPARα.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1488722

By:

Ammazzalorso, Alessandra;
Tacconelli, Stefania;
Contursi, Annalisa;
Hofling, Ulrika;
Cerchia, Carmen;
Di Berardino, Sara;
De Michele, Alessandra;
Amoroso, Rosa;
Lavecchia, Antonio;
Patrignani, Paola

Publication type:

Article

In Silico Drug Design and Discovery: Big Data for Small Molecule Design.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 44, doi. 10.3390/biom13010044

By:

Cerchia, Carmen;
Lavecchia, Antonio

Publication type:

Article