Works matching AU Cathomen, Toni

Results: 76

Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06959-z

By:

Raimondi, Federica;
Siow, Kah Mun;
Wrona, Dominik;
Fuster-García, Carla;
Pastukhov, Oleksandr;
Schmitz, Michael;
Bargsten, Katja;
Kissling, Lucas;
Swarts, Daan C.;
Andrieux, Geoffroy;
Cathomen, Toni;
Modlich, Ute;
Jinek, Martin;
Siler, Ulrich;
Reichenbach, Janine

Publication type:

Article

The Scope for Thalassemia Gene Therapy by Disruption of Aberrant Regulatory Elements.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1959, doi. 10.3390/jcm8111959

By:

Patsali, Petros;
Mussolino, Claudio;
Ladas, Petros;
Floga, Argyro;
Kolnagou, Annita;
Christou, Soteroula;
Sitarou, Maria;
Antoniou, Michael N.;
Cathomen, Toni;
Lederer, Carsten Werner;
Kleanthous, Marina

Publication type:

Article

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06409

By:

Mock, Ulrike;
Riecken, Kristoffer;
Berdien, Belinda;
Qasim, Waseem;
Chan, Emma;
Cathomen, Toni;
Fehse, Boris

Publication type:

Article

Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04656

By:

Bobis-Wozowicz, Sylwia;
Galla, Melanie;
Alzubi, Jamal;
Kuehle, Johannes;
Baum, Christopher;
Schambach, Axel;
Cathomen, Toni

Publication type:

Article

Artificial Targets: a versatile cell-free platform to characterize CAR T cell function in vitro.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1254162

By:

Xueting Wang;
Tokarew, Nicholas J. A.;
Borgelt, Nadine;
Siemer, Ramona;
Melo, Cristiane Casonato;
Langer, Christian;
Kasampalidis, Ioannis;
Ogusuku, Isabella E. Y.;
Cathomen, Toni;
Gessner, Isabel;
Dose, Christian;
Fauerbach, Jonathan A.;
Richter, Anne;
Evaristo, César

Publication type:

Article

CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52388-1

By:

Bexte, Tobias;
Albinger, Nawid;
Al Ajami, Ahmad;
Wendel, Philipp;
Buchinger, Leon;
Gessner, Alec;
Alzubi, Jamal;
Särchen, Vinzenz;
Vogler, Meike;
Rasheed, Hadeer Mohamed;
Jung, Beate Anahita;
Wolf, Sebastian;
Bhayadia, Raj;
Oellerich, Thomas;
Klusmann, Jan-Henning;
Penack, Olaf;
Möker, Nina;
Cathomen, Toni;
Rieger, Michael A.;
Imkeller, Katharina

Publication type:

Article

Adapter-Mediated Transduction with Lentiviral Vectors: A Novel Tool for Cell-Type-Specific Gene Transfer.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/v14102157

By:

Cordes, Nicole;
Winter, Nora;
Kolbe, Carolin;
Kotter, Bettina;
Mittelstaet, Joerg;
Assenmacher, Mario;
Cathomen, Toni;
Kaiser, Andrew;
Schaser, Thomas

Publication type:

Article

Improved Specificity and Safety of Anti-Hepatitis B Virus TALENs Using Obligate Heterodimeric Fok I Nuclease Domains.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 7, p. 1344, doi. 10.3390/v13071344

By:

Smith, Tiffany;
Singh, Prashika;
Chmielewski, Kay Ole;
Bloom, Kristie;
Cathomen, Toni;
Arbuthnot, Patrick;
Ely, Abdullah

Publication type:

Article

A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.

Published in:

EMBO Journal, 1998, v. 17, n. 14, p. 3899, doi. 10.1093/emboj/17.14.3899

By:

Cathomen, Toni;
Mrkic, Branka;
Spehner, Danièle;
Drillien, Robert;
Naef, Roland;
Pavlovic, Jovan;
Aguzzi, Adriano;
Billeter, Martin A.;
Cattaneo, Roberto

Publication type:

Article

Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03117-w

By:

Paw, Milena;
Kusiak, Agnieszka A.;
Nit, Kinga;
Litewka, Jacek J.;
Piejko, Marcin;
Wnuk, Dawid;
Sarna, Michał;
Fic, Kinga;
Stopa, Kinga B.;
Hammad, Ruba;
Barczyk-Woznicka, Olga;
Cathomen, Toni;
Zuba-Surma, Ewa;
Madeja, Zbigniew;
Ferdek, Paweł E.;
Bobis-Wozowicz, Sylwia

Publication type:

Article

Cell-Based Models of 'Cytokine Release Syndrome' Endorse CD40L and Granulocyte–Macrophage Colony-Stimulating Factor Knockout in Chimeric Antigen Receptor T Cells as Mitigation Strategy.

Published in:

Cells (2073-4409), 2023, v. 12, n. 21, p. 2581, doi. 10.3390/cells12212581

By:

Dibas, Ala;
Rhiel, Manuel;
Patel, Vidisha Bhavesh;
Andrieux, Geoffroy;
Boerries, Melanie;
Cornu, Tatjana I.;
Alzubi, Jamal;
Cathomen, Toni

Publication type:

Article

Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 23, p. 3752, doi. 10.3390/cells11233752

By:

Polisetti, Naresh;
Rapp, Julian;
Liang, Paula;
Dettmer-Monaco, Viviane;
Bucher, Felicitas;
Pruszak, Jan;
Schlötzer-Schrehardt, Ursula;
Cathomen, Toni;
Schlunck, Günther;
Reinhard, Thomas

Publication type:

Article

Genome Editing of the SNAI1 Gene in Rhabdomyosarcoma: A Novel Model for Studies of Its Role.

Published in:

Cells (2073-4409), 2020, v. 9, n. 5, p. 1095, doi. 10.3390/cells9051095

By:

Ulman, Aleksandra;
Skrzypek, Klaudia;
Konieczny, Paweł;
Mussolino, Claudio;
Cathomen, Toni;
Majka, Marcin

Publication type:

Article

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 5, p. e63, doi. 10.1093/nar/gks1446

By:

Holkers, Maarten;
Maggio, Ignazio;
Liu, Jin;
Janssen, Josephine M.;
Miselli, Francesca;
Mussolino, Claudio;
Recchia, Alessandra;
Cathomen, Toni;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Retargeting transposon insertions by the adeno-associated virus Rep protein.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 14, p. 6693, doi. 10.1093/nar/gks317

By:

Ammar, Ismahen;
Gogol-Döring, Andreas;
Miskey, Csaba;
Chen, Wei;
Cathomen, Toni;
Izsvák, Zsuzsanna;
Ivics, Zoltán

Publication type:

Article

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 13, p. 5560, doi. 10.1093/nar/gks179

By:

Ramirez, Cherie L.;
Certo, Michael T.;
Mussolino, Claudio;
Goodwin, Mathew J.;
Cradick, Thomas J.;
McCaffrey, Anton P.;
Cathomen, Toni;
Scharenberg, Andrew M.;
Joung, J. Keith

Publication type:

Article

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 12, p. 5560, doi. 10.1093/nar/gks179

By:

Ramirez, Cherie L.;
Certo, Michael T.;
Mussolino, Claudio;
Goodwin, Mathew J.;
Cradick, Thomas J.;
McCaffrey, Anton P.;
Cathomen, Toni;
Scharenberg, Andrew M.;
Joung, J. Keith

Publication type:

Article

A novel zinc-finger nuclease platform with a sequence-specific cleavage module.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 6, p. 2623, doi. 10.1093/nar/gkr1112

By:

Schierling, Benno;
Dannemann, Nadine;
Gabsalilow, Lilia;
Wende, Wolfgang;
Cathomen, Toni;
Pingoud, Alfred

Publication type:

Article

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 21, p. 9283, doi. 10.1093/nar/gkr597

By:

Mussolino, Claudio;
Morbitzer, Robert;
Lütge, Fabienne;
Dannemann, Nadine;
Lahaye, Thomas;
Cathomen, Toni

Publication type:

Article

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 22, p. 8269

By:

Şöllü, Cem;
Pars, Kaweh;
Cornu, Tatjana I.;
Thibodeau-Beganny, Stacey;
Maeder, Morgan L.;
Joung, J. Keith;
Heilbronn, Regine;
Cathomen, Toni

Publication type:

Article

Assessing the differential impact of chronic CMV and treated HIV infection on CD8+ T-cell differentiation in a matched cohort study: is CMV the key?

Published in:

AIDS Research & Therapy, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12981-021-00361-z

By:

Mueller, Matthias C.;
Kern, Winfried V.;
Usadel, Susanne;
Pauly, Marie-Christin;
Cathomen, Toni;
Salzer, Ulrich

Publication type:

Article

Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.

Published in:

PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005239

By:

Rahman, Shamim H.;
Kuehle, Johannes;
Reimann, Christian;
Mlambo, Tafadzwa;
Alzubi, Jamal;
Maeder, Morgan L.;
Riedel, Heimo;
Fisch, Paul;
Cantz, Tobias;
Rudolph, Cornelia;
Mussolino, Claudio;
Joung, J. Keith;
Schambach, Axel;
Cathomen, Toni

Publication type:

Article

P1357: MILESTONE (MODIFYING ELANE GOLDBERG–HOGNES BOX TO INHIBIT EXPRESSION), A UNIVERSAL, SAFE AND EFFECTIVE CRISPR/CAS9N‐MEDIATED GENOME EDITING STRATEGY FOR ELANE RELATED SEVERE CONGENITAL NEUTROPENIA.

Published in:

HemaSphere, 2023, v. 7, p. 1, doi. 10.1097/01.HS9.0000972316.76856.78

By:

Nasri, Masoud;
Ulrich Ritter, Malte;
Mir, Perihan;
Dannenmann, Benjamin;
Monika Kaufmann, Masako;
Xu, Yun;
Borbaran‐Bravo, Natalia;
Klimiankou, Maksim;
Lengerke, Claudia;
Zeidler, Cornelia;
Cathomen, Toni;
Welte, Karl;
Skokowa, Julia

Publication type:

Article

P1354: CRISPR/CAS9 GENE EDITING OF IMMUNE CHECKPOINT RECEPTOR NKG2A IMPROVES THE ANTI-LEUKEMIC EFFICACY OF PRIMARY CD33-TARGETING CAR-NK CELLS.

Published in:

2023

By:

Albinger, Nawid;
Bexte, Tobias;
Al-Ajami, Ahmad;
Wendel, Philipp;
Buchinger, Leon;
Gessner, Alec;
Alzubi, Jamal;
Särchen, Vinzenz;
Vogler, Meike;
Bhayadia, Raj;
Klusmann, Jan-Henning;
Möker, Nina;
Cathomen, Toni;
Rieger, Michael A.;
Imkeller, Katharina;
Ullrich, Evelyn

Publication type:

Abstract

Immunopathology caused by impaired CD8<sup>+</sup> T‐cell responses.

Published in:

European Journal of Immunology, 2022, v. 52, n. 9, p. 1390, doi. 10.1002/eji.202149528

By:

Aichele, Peter;
Neumann‐Haefelin, Christoph;
Ehl, Stephan;
Thimme, Robert;
Cathomen, Toni;
Boerries, Melanie;
Hofmann, Maike

Publication type:

Article

Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells.

Published in:

Genes, 2022, v. 13, n. 10, p. N.PAG, doi. 10.3390/genes13101912

By:

König, Saskia;
Fliegauf, Manfred;
Rhiel, Manuel;
Grimbacher, Bodo;
Cornu, Tatjana I.;
Cathomen, Toni;
Mussolino, Claudio

Publication type:

Article

Biodegradable Nanocarriers Resembling Extracellular Vesicles Deliver Genetic Material with the Highest Efficiency to Various Cell Types.

Published in:

Small, 2020, v. 16, n. 3, p. N.PAG, doi. 10.1002/smll.201904880

By:

Tarakanchikova, Yana;
Alzubi, Jamal;
Pennucci, Valentina;
Follo, Marie;
Kochergin, Boris;
Muslimov, Albert;
Skovorodkin, Ilya;
Vainio, Seppo;
Antipina, Maria N.;
Atkin, Vsevolod;
Popov, Alexey;
Meglinski, Igor;
Cathomen, Toni;
Cornu, Tatjana I.;
Gorin, Dmitry A.;
Sukhorukov, Gleb B.;
Nazarenko, Irina

Publication type:

Article

Targeted Integration of a Super-Exon into the CFTR Locus Leads to Functional Correction of a Cystic Fibrosis Cell Line Model.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161072

By:

Bednarski, Christien;
Tomczak, Katja;
vom Hövel, Beate;
Weber, Wolf-Michael;
Cathomen, Toni

Publication type:

Article

CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 985, doi. 10.3390/ijms25020985

By:

Hammad, Ruba;
Alzubi, Jamal;
Rhiel, Manuel;
Chmielewski, Kay O.;
Mosti, Laura;
Rositzka, Julia;
Heugel, Marcel;
Lawrenz, Jan;
Pennucci, Valentina;
Gläser, Birgitta;
Fischer, Judith;
Schambach, Axel;
Moritz, Thomas;
Lachmann, Nico;
Cornu, Tatjana I.;
Mussolino, Claudio;
Schäfer, Richard;
Cathomen, Toni

Publication type:

Article

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2481, doi. 10.3390/ijms21072481

By:

Lipus, Alexandra;
Janosz, Ewa;
Ackermann, Mania;
Hetzel, Miriam;
Dahlke, Julia;
Buchegger, Theresa;
Wunderlich, Stephanie;
Martin, Ulrich;
Cathomen, Toni;
Schambach, Axel;
Moritz, Thomas;
Lachmann, Nico

Publication type:

Article

Chimerization Enables Gene Synthesis and Lentiviral Delivery of Customizable TALE-Based Effectors.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 795, doi. 10.3390/ijms21030795

By:

Fang, Yongxing;
Stroukov, Wladislaw;
Cathomen, Toni;
Mussolino, Claudio

Publication type:

Article

From CRISPR screens to circuits: identifying key regulators in T cell activation and state transitions.

Published in:

Signal Transduction & Targeted Therapy, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41392-025-02200-3

By:

Roman Azcona, Maria Silvia;
Cathomen, Toni;
Mussolino, Claudio

Publication type:

Article

CRISPR-Cas9 based gene editing of the immune checkpoint NKG2A enhances NK cell mediated cytotoxicity against multiple myeloma.

Published in:

OncoImmunology, 2022, v. 11, n. 1, p. 1, doi. 10.1080/2162402X.2022.2081415

By:

Bexte, Tobias;
Alzubi, Jamal;
Reindl, Lisa Marie;
Wendel, Philipp;
Schubert, Ralf;
Salzmann-Manrique, Emilia;
von Metzler, Ivana;
Cathomen, Toni;
Ullrich, Evelyn

Publication type:

Article

Deciphering the impact of parameters influencing transgene expression kinetics after repeated cell transduction with integration-deficient retroviral vectors.

Published in:

Cytometry. Part A, 2015, v. 87, n. 5, p. 405, doi. 10.1002/cyto.a.22650

By:

Schott, Juliane W.;
Jaeschke, Nico M.;
Hoffmann, Dirk;
Maetzig, Tobias;
Ballmaier, Matthias;
Godinho, Tamaryin;
Cathomen, Toni;
Schambach, Axel

Publication type:

Article

A versatile reporter system for multiplexed screening of effective epigenome editors.

Published in:

Nature Protocols, 2020, v. 15, n. 10, p. 3410, doi. 10.1038/s41596-020-0380-y

By:

Roman Azcona, Maria Silvia;
Fang, Yongxing;
Carusillo, Antonio;
Cathomen, Toni;
Mussolino, Claudio

Publication type:

Article

Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA.

Published in:

2019

By:

Bloom, Kristie;
Kaldine, Haajira;
Cathomen, Toni;
Mussolino, Claudio;
Ely, Abdullah;
Arbuthnot, Patrick

Publication type:

journal article

Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48934-6

By:

Kessler, Susanne;
Burke, Bradly;
Andrieux, Geoffroy;
Schinköthe, Jan;
Hamberger, Lea;
Kacza, Johannes;
Shijun Zhan;
Reasoner, Clara;
Dutt, Taru S.;
Osman, Maria Kaukab;
Henao-Tamayo, Marcela;
Staniek, Julian;
Villena Ossa, Jose Francisco;
Frank, Dalit T.;
Wenjun Ma;
Ulrich, Reiner;
Cathomen, Toni;
Boerries, Melanie;
Rizzi, Marta;
Beer, Martin

Publication type:

Article

An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1648, doi. 10.3390/cancers12061648

By:

Masilamani, Anie P.;
Dettmer-Monaco, Viviane;
Monaco, Gianni;
Cathomen, Toni;
Kuckuck, Irina;
Schultze-Seemann, Susanne;
Huber, Nathalie;
Wolf, Philipp

Publication type:

Article

Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH).

Published in:

EMBO Molecular Medicine, 2022, v. 14, n. 12, p. 1, doi. 10.15252/emmm.202216085

By:

Weißert, Kristoffer;
Ammann, Sandra;
Kögl, Tamara;
Dettmer‐Monaco, Viviane;
Schell, Christoph;
Cathomen, Toni;
Ehl, Stephan;
Aichele, Peter

Publication type:

Article

Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01722-7

By:

Bobis-Wozowicz, Sylwia;
Paw, Milena;
Sarna, Michał;
Kędracka-Krok, Sylwia;
Nit, Kinga;
Błażowska, Natalia;
Dobosz, Anna;
Hammad, Ruba;
Cathomen, Toni;
Zuba-Surma, Ewa;
Tyszka-Czochara, Małgorzata;
Madeja, Zbigniew

Publication type:

Article

Integration Preferences of Wildtype AAV-2 for Consensus Rep-Binding Sites at Numerous Loci in the Human Genome.

Published in:

PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1000985

By:

Hüser, Daniela;
Gogol-Döring, Andreas;
Lutter, Timo;
Weger, Stefan;
Winter, Kerstin;
Hammer, Eva-Maria;
Cathomen, Toni;
Reinert, Knut;
Heilbronn, Regine

Publication type:

Article

Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease.

Published in:

PLoS Pathogens, 2009, v. 5, n. 8, p. 1, doi. 10.1371/journal.ppat.1000558

By:

Ermolayev, Vladimir;
Cathomen, Toni;
Merk, Julia;
Friedrich, Mike;
Härtig, Wolfgang;
Harms, Gregory S.;
Klein, Michael A.;
Flechsig, Eckhard

Publication type:

Article

Genome Editing Technologies: Defining a Path to Clinic.

Published in:

Molecular Therapy, 2015, v. 23, n. 5, p. 796, doi. 10.1038/mt.2015.54

By:

Corrigan-Curay, Jacqueline;
O'Reilly, Marina;
Kohn, Donald B;
Cannon, Paula M;
Bao, Gang;
Bushman, Frederic D;
Carroll, Dana;
Cathomen, Toni;
Joung, J Keith;
Roth, David;
Sadelain, Michel;
Scharenberg, Andrew M;
von Kalle, Christof;
Zhang, Feng;
Jambou, Robert;
Rosenthal, Eugene;
Hassani, Morad;
Singh, Aparna;
Porteus, Matthew H

Publication type:

Article

Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1889, doi. 10.1038/mt.2013.170

By:

Bloom, Kristie;
Ely, Abdullah;
Mussolino, Claudio;
Cathomen, Toni;
Arbuthnot, Patrick

Publication type:

Article

Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases.

Published in:

Molecular Therapy, 2013, v. 21, n. 2, p. 266, doi. 10.1038/mt.2013.4

By:

Tremblay, Jacques P;
Xiao, Xiao;
Aartsma-Rus, Annemieke;
Barbas, Carlos;
Blau, Helen M;
Bogdanove, Adam J;
Boycott, Kym;
Braun, Serge;
Breakefield, Xandra O;
Bueren, Juan A;
Buschmann, Michael;
Byrne, Barry J;
Calos, Michele;
Cathomen, Toni;
Chamberlain, Jeffrey;
Chuah, Marinee;
Cornetta, Kenneth;
Davies, Kay E;
Dickson, J George;
Duchateau, Philippe

Publication type:

Article

Retargeting Sleeping Beauty Transposon Insertions by Engineered Zinc Finger DNA-binding Domains.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1852, doi. 10.1038/mt.2012.126

By:

Voigt, Katrin;
Gogol-Döring, Andreas;
Miskey, Csaba;
Chen, Wei;
Cathomen, Toni;
Izsvák, Zsuzsanna;
Ivics, Zoltán

Publication type:

Article

Zinc-finger Nuclease-induced Gene Repair With Oligodeoxynucleotides: Wanted and Unwanted Target Locus Modifications.

Published in:

Molecular Therapy, 2010, v. 18, n. 4, p. 743, doi. 10.1038/mt.2009.304

By:

Radecke, Sarah;
Radecke, Frank;
Cathomen, Toni;
Schwarz, Klaus

Publication type:

Article

Expanding or Restricting the Target Site Repertoire of Zinc-finger Nucleases: The Inter-domain Linker as a Major Determinant of Target Site Selectivity.

Published in:

Molecular Therapy, 2009, v. 17, n. 1, p. 104, doi. 10.1038/mt.2008.233

By:

Händel, Eva-Maria;
Alwin, Stephen;
Cathomen, Toni

Publication type:

Article

Zinc-finger Nucleases: The Next Generation Emerges.

Published in:

Molecular Therapy, 2008, v. 16, n. 7, p. 1200, doi. 10.1038/mt.2008.114

By:

Cathomen, Toni;
Keith Joung, J.

Publication type:

Article

DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases.

Published in:

Molecular Therapy, 2008, v. 16, n. 2, p. 352, doi. 10.1038/sj.mt.6300357

By:

Cornu, Tatjana I.;
Thibodeau-Beganny, Stacey;
Guhl, Eva;
Alwin, Stephen;
Eichtinger, Magdalena;
Joung, J. K.;
Cathomen, Toni

Publication type:

Article