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Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr−/−.Leiden mice.
Published in:
FASEB Journal, 2024, v. 38, n. 20, p. 1, doi. 10.1096/fj.202401397R
By:
- Inia, José A.;
- Attema, Joline;
- de Ruiter, Christa;
- Menke, Aswin L.;
- Caspers, Martien P. M.;
- Verschuren, Lars;
- Wilson, Maria;
- Arlantico, Alexander;
- Brightbill, Hans D.;
- Jukema, J. Wouter;
- van den Hoek, Anita M.;
- Princen, Hans M. G.;
- Chen, Mark Z.;
- Morrison, Martine C.
Publication type:
Article
Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8494, doi. 10.3390/ijms24108494
By:
- Inia, José A.;
- Stokman, Geurt;
- Morrison, Martine C.;
- Worms, Nicole;
- Verschuren, Lars;
- Caspers, Martien P. M.;
- Menke, Aswin L.;
- Petitjean, Louis;
- Chen, Li;
- Petitjean, Mathieu;
- Jukema, J. Wouter;
- Princen, Hans M. G.;
- van den Hoek, Anita M.
Publication type:
Article
Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7818, doi. 10.3390/ijms24097818
By:
- Inia, José A.;
- Stokman, Geurt;
- Pieterman, Elsbet J.;
- Morrison, Martine C.;
- Menke, Aswin L.;
- Verschuren, Lars;
- Caspers, Martien P. M.;
- Giera, Martin;
- Jukema, J. Wouter;
- van den Hoek, Anita M.;
- Princen, Hans M. G.
Publication type:
Article
Unraveling the Transcriptional Dynamics of NASH Pathogenesis Affecting Atherosclerosis.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8229, doi. 10.3390/ijms23158229
By:
- van den Hoek, Anita M.;
- Özsezen, Serdar;
- Caspers, Martien P. M.;
- van Koppen, Arianne;
- Hanemaaijer, Roeland;
- Verschuren, Lars
Publication type:
Article
Deep Sequencing Analyses of Low Density Microbial Communities: Working at the Boundary of Accurate Microbiota Detection.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032942
By:
- Biesbroek, Giske;
- Sanders, Elisabeth A. M.;
- Roeselers, Guus;
- Wang, Xinhui;
- Caspers, Martien P. M.;
- Trzciński, Krzysztof;
- Bogaert, Debby;
- Keijser, Bart J. F.
Publication type:
Article
Genomic Diversity within the Enterobacter cloacae Complex.
Published in:
PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0003018
By:
- Paauw, Armand;
- Caspers, Martien P. M.;
- Schuren, Frank H. J.;
- Leverstein-van Hall, Maurine A.;
- Delétoile, Alexis;
- Montijn, Roy C.;
- Verhoef, Jan;
- Fluit, Ad C.
Publication type:
Article
Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody.
Published in:
Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1205261
By:
- Seidel, Florine;
- Fluiter, Kees;
- Kleemann, Robert;
- Worms, Nicole;
- Nieuwkoop, Anita van;
- Caspers, Martien P. M.;
- Grigoriadis, Nikolaos;
- Kiliaan, Amanda J.;
- Baas, Frank;
- Michailidou, Iliana;
- Morrison, Martine C.
Publication type:
Article
Translatability of mouse muscle-aging for humans: the role of sex.
Published in:
GeroScience, 2024, v. 46, n. 3, p. 3341, doi. 10.1007/s11357-024-01082-7
By:
- de Jong, Jelle C. B. C.;
- Caspers, Martien P. M.;
- Worms, Nicole;
- Keijzer, Nanda;
- Kleemann, Robert;
- Menke, Aswin L.;
- Nieuwenhuizen, Arie G.;
- Keijer, Jaap;
- Verschuren, Lars;
- van den Hoek, Anita M.
Publication type:
Article
Evidence for sex-specific intramuscular changes associated to physical weakness in adults older than 75 years.
Published in:
Biology of Sex Differences, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13293-023-00531-w
By:
- de Jong, Jelle C. B. C.;
- Verschuren, Lars;
- Caspers, Martien P. M.;
- van der Hoek, Marjanne D.;
- van der Leij, Feike R.;
- Kleemann, Robert;
- van den Hoek, Anita M.;
- Nieuwenhuizen, Arie G.;
- Keijer, Jaap
Publication type:
Article
Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.
Published in:
FASEB Journal, 2022, v. 36, n. 8, p. 1, doi. 10.1096/fj.202200111R
By:
- Gart, Eveline;
- van Duyvenvoorde, Wim;
- Caspers, Martien P. M.;
- van Trigt, Nikki;
- Snabel, Jessica;
- Menke, Aswin;
- Keijer, Jaap;
- Salic, Kanita;
- Morrison, Martine C.;
- Kleemann, Robert
Publication type:
Article
Insertion Sequence--Driven Diversification Creates a Globally Dispersed Emerging Multiresistant Subspecies of E. faecium.
Published in:
PLoS Pathogens, 2007, v. 3, n. 1, p. 75, doi. 10.1371/journal.ppat.0030007
By:
- Leavis, Helen L.;
- Willems, Rob J. L.;
- van Wamel, Willem J. B.;
- Schuren, Frank H.;
- Caspers, Martien P. M.;
- Bonten, Marc J. M.
Publication type:
Article
Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83974-8
By:
- van den Hoek, Anita M.;
- Verschuren, Lars;
- Caspers, Martien P. M.;
- Worms, Nicole;
- Menke, Aswin L.;
- Princen, Hans M. G.
Publication type:
Article
Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells.
Published in:
Biomedicines, 2021, v. 9, n. 12, p. 1954, doi. 10.3390/biomedicines9121954
By:
- Gart, Eveline;
- van Duyvenvoorde, Wim;
- Toet, Karin;
- Caspers, Martien P. M.;
- Verschuren, Lars;
- Nielsen, Mette Juul;
- Leeming, Diana Julie;
- Souto Lima, Everton;
- Menke, Aswin;
- Hanemaaijer, Roeland;
- Keijer, Jaap;
- Salic, Kanita;
- Kleemann, Robert;
- Morrison, Martine C.
Publication type:
Article
A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology.
Published in:
Cells (2073-4409), 2020, v. 9, n. 9, p. 2014, doi. 10.3390/cells9092014
By:
- van den Hoek, Anita M.;
- Verschuren, Lars;
- Worms, Nicole;
- van Nieuwkoop, Anita;
- de Ruiter, Christa;
- Attema, Joline;
- Menke, Aswin L.;
- Caspers, Martien P. M.;
- Radhakrishnan, Sridhar;
- Salic, Kanita;
- Kleemann, Robert
Publication type:
Article
Caloric Restriction Combined with Immobilization as Translational Model for Sarcopenia Expressing Key-Pathways of Human Pathology.
Published in:
Aging & Disease, 2023, v. 14, n. 3, p. 937, doi. 10.14336/AD.2022.1201
By:
- de Jong, Jelle C. B. C.;
- Caspers, Martien P. M.;
- Keijzer, Nanda;
- Worms, Nicole;
- Attema, Joline;
- de Ruiter, Christa;
- Lek, Serene;
- Nieuwenhuizen, Arie G.;
- Keijer, Jaap;
- Menke, Aswin L.;
- Kleemann, Robert;
- Verschuren, Lars;
- den Hoek, Anita M. van
Publication type:
Article
Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48956-0
By:
- Verschuren, Lars;
- Mak, Anne Linde;
- van Koppen, Arianne;
- Özsezen, Serdar;
- Difrancesco, Sonia;
- Caspers, Martien P. M.;
- Snabel, Jessica;
- van der Meer, David;
- van Dijk, Anne-Marieke;
- Rashu, Elias Badal;
- Nabilou, Puria;
- Werge, Mikkel Parsberg;
- van Son, Koen;
- Kleemann, Robert;
- Kiliaan, Amanda J.;
- Hazebroek, Eric J.;
- Boonstra, André;
- Brouwer, Willem P.;
- Doukas, Michail;
- Gupta, Saurabh
Publication type:
Article
Mechanism-Based Biomarker Prediction for Low-Grade Inflammation in Liver and Adipose Tissue.
Published in:
Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.703370
By:
- van Bilsen, Jolanda H. M.;
- van den Brink, Willem;
- van den Hoek, Anita M.;
- Dulos, Remon;
- Caspers, Martien P. M.;
- Kleemann, Robert;
- Wopereis, Suzan;
- Verschuren, Lars
Publication type:
Article
Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity.
Published in:
2016
By:
- Dols, Joke A. M.;
- Molenaar, Douwe;
- van der Helm, Jannie J.;
- Caspers, Martien P. M.;
- de Kat Angelino-Bart, Alie;
- Schuren, Frank H. J.;
- Speksnijder, Adrianus G. C. L.;
- Westerhoff, Hans V.;
- Richardus, Jan Hendrik;
- Boon, Mathilde E.;
- Reid, Gregor;
- de Vries, Henry J. C.;
- Kort, Remco
Publication type:
journal article
Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice.
Published in:
Toxicological Sciences, 2019, v. 168, n. 2, p. 519, doi. 10.1093/toxsci/kfz015
By:
- Pouwer, Marianne G;
- Pieterman, Elsbet J;
- Chang, Shu-Ching;
- Olsen, Geary W;
- Caspers, Martien P M;
- Verschuren, Lars;
- Jukema, J Wouter;
- Princen, Hans M G
Publication type:
Article
Integrating text mining with network models for successful target identification: in vitro validation in MASH-induced liver fibrosis.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1442752
By:
- Venhorst, Jennifer;
- Hanemaaijer, Roeland;
- Dulos, Remon;
- Caspers, Martien P. M.;
- Toet, Karin;
- Attema, Joline;
- de Ruiter, Christa;
- Kalkman, Gino;
- Rankouhi, Tanja Rouhani;
- de Jong, Jelle C. B. C.;
- Verschuren, Lars
Publication type:
Article
Integrating text mining with network models for successful target identification: in vitro validation in MASH-induced liver fibrosis.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1442752
By:
- Venhorst, Jennifer;
- Hanemaaijer, Roeland;
- Dulos, Remon;
- Caspers, Martien P. M.;
- Toet, Karin;
- Attema, Joline;
- de Ruiter, Christa;
- Kalkman, Gino;
- Rankouhi, Tanja Rouhani;
- de Jong, Jelle C. B. C.;
- Verschuren, Lars
Publication type:
Article
A Novel Personalized Systems Nutrition Program Improves Dietary Patterns, Lifestyle Behaviors and Health-Related Outcomes: Results from the Habit Study.
Published in:
Nutrients, 2021, v. 13, n. 6, p. 1763, doi. 10.3390/nu13061763
By:
- de Hoogh, Iris M.;
- Winters, Barbara L.;
- Nieman, Kristin M.;
- Bijlsma, Sabina;
- Krone, Tanja;
- van den Broek, Tim J.;
- Anderson, Barbara D.;
- Caspers, Martien P. M.;
- Anthony, Joshua C.;
- Wopereis, Suzan
Publication type:
Article
Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody.
Published in:
Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1205261
By:
- Seidel, Florine;
- Fluiter, Kees;
- Kleemann, Robert;
- Worms, Nicole;
- van Nieuwkoop, Anita;
- Caspers, Martien P. M.;
- Grigoriadis, Nikolaos;
- Kiliaan, Amanda J.;
- Baas, Frank;
- Michailidou, Iliana;
- Morrison, Martine C.
Publication type:
Article

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