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A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.
Published in:
2017
By:
- Mollenhauer, Brit;
- Batrla, Richard;
- El‐Agnaf, Omar;
- Galasko, Douglas R.;
- Lashuel, Hilal A.;
- Merchant, Kalpana M.;
- Shaw, Lesley M.;
- Selkoe, Dennis J.;
- Umek, Robert;
- Vanderstichele, Hugo;
- Zetterberg, Henrik;
- Zhang, Jing;
- Caspell‐Garcia, Chelsea;
- Coffey, Chris;
- Hutten, Samantha J.;
- Frasier, Mark;
- Taylor, Peggy;
- El-Agnaf, Omar;
- Caspell-Garcia, Chelsea;
- Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research
Publication type:
journal article
The prodromal phase of leucine-rich repeat kinase 2-associated Parkinson disease: Clinical and imaging Studies.
Published in:
2017
By:
- Pont‐Sunyer, Claustre;
- Tolosa, Eduardo;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher;
- Alcalay, Roy N.;
- Chan, Piu;
- Duda, John E.;
- Facheris, Maurizio;
- Fernández‐Santiago, Rubén;
- Marek, Kenneth;
- Lomeña, Francisco;
- Marras, Connie;
- Mondragon, Elisabet;
- Saunders‐Pullman, Rachel;
- Waro, Bjorg;
- Pont-Sunyer, Claustre;
- Caspell-Garcia, Chelsea;
- Fernández-Santiago, Rubén;
- Lomeña, Francisco;
- Saunders-Pullman, Rachel
Publication type:
journal article
Association of Baseline Depression and Anxiety with Longitudinal Health Outcomes in Parkinson's Disease.
Published in:
Movement Disorders Clinical Practice, 2024, v. 11, n. 9, p. 1103, doi. 10.1002/mdc3.14145
By:
- Shi, Yiwen;
- Dobkin, Roseanne;
- Weintraub, Daniel;
- Cho, Hyunkeun R.;
- Caspell‐Garcia, Chelsea;
- Bock, Meredith;
- Brown, Ethan;
- Aarsland, Dag;
- Dahodwala, Nabila
Publication type:
Article
Impact of the Dopamine System on Long‐Term Cognitive Impairment in Parkinson Disease: An Exploratory Study.
Published in:
Movement Disorders Clinical Practice, 2023, v. 10, n. 6, p. 943, doi. 10.1002/mdc3.13751
By:
- Weintraub, Daniel;
- Picillo, Marina;
- Cho, Hyunkeun Ryan;
- Caspell‐Garcia, Chelsea;
- Blauwendraat, Cornelis;
- Brown, Ethan G.;
- Chahine, Lana M.;
- Coffey, Christopher S.;
- Dobkin, Roseanne D.;
- Foroud, Tatiana;
- Galasko, Doug;
- Kieburtz, Karl;
- Marek, Kenneth;
- Merchant, Kalpana;
- Mollenhauer, Brit;
- Poston, Kathleen L.;
- Simuni, Tanya;
- Siderowf, Andrew;
- Singleton, Andrew;
- Seibyl, John
Publication type:
Article
Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
2021
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Cofey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Correction Notice
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Coffey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Article
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Coffey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Article
Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial.
Published in:
JAMA Neurology, 2021, v. 78, n. 3, p. 312, doi. 10.1001/jamaneurol.2020.4725
By:
- Simuni, Tanya;
- Fiske, Brian;
- Merchant, Kalpana;
- Coffey, Christopher S.;
- Klingner, Elizabeth;
- Caspell-Garcia, Chelsea;
- Lafontant, David-Erick;
- Matthews, Helen;
- Wyse, Richard K.;
- Brundin, Patrik;
- Simon, David K.;
- Schwarzschild, Michael;
- Weiner, David;
- Adams, Jamie;
- Venuto, Charles;
- Dawson, Ted M.;
- Baker, Liana;
- Kostrzebski, Melissa;
- Ward, Tina;
- Rafaloff, Gary
Publication type:
Article
LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts.
Published in:
NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00468-2
By:
- Merchant, Kalpana M.;
- Simuni, Tanya;
- Fedler, Janel;
- Caspell-Garcia, Chelsea;
- Brumm, Michael;
- Nudelman, Kelly N. H.;
- Tengstrandt, Elizabeth;
- Hsieh, Frank;
- Alcalay, Roy N.;
- Coffey, Christopher;
- Chahine, Lana;
- Foroud, Tatiana;
- Singleton, Andrew;
- Weintraub, Daniel;
- Hutten, Samantha;
- Sherer, Todd;
- Mollenhauer, Brit;
- Siderowf, Andrew;
- Tanner, Caroline;
- Marek, Ken
Publication type:
Article
LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts.
Published in:
NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00468-2
By:
- Merchant, Kalpana M.;
- Simuni, Tanya;
- Fedler, Janel;
- Caspell-Garcia, Chelsea;
- Brumm, Michael;
- Nudelman, Kelly N. H.;
- Tengstrandt, Elizabeth;
- Hsieh, Frank;
- Alcalay, Roy N.;
- Coffey, Christopher;
- Chahine, Lana;
- Foroud, Tatiana;
- Singleton, Andrew;
- Weintraub, Daniel;
- Hutten, Samantha;
- Sherer, Todd;
- Mollenhauer, Brit;
- Siderowf, Andrew;
- Tanner, Caroline;
- Marek, Ken
Publication type:
Article
Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort.
Published in:
NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00404-w
By:
- Simuni, Tanya;
- Merchant, Kalpana;
- Brumm, Michael C.;
- Cho, Hyunkeun;
- Caspell-Garcia, Chelsea;
- Coffey, Christopher S.;
- Chahine, Lana M.;
- Alcalay, Roy N.;
- Nudelman, Kelly;
- Foroud, Tatiana;
- Mollenhauer, Brit;
- Siderowf, Andrew;
- Tanner, Caroline;
- Iwaki, Hirotaka;
- Sherer, Todd;
- Marek, Kenneth;
- Parkinson's Progression Marker Initiative Authors;
- Steering Committee;
- Seibyl, John;
- Coffey, Christopher
Publication type:
Article
Dopamine transporter imaging predicts clinically‐defined α‐synucleinopathy in REM sleep behavior disorder.
Published in:
Annals of Clinical & Translational Neurology, 2021, v. 8, n. 1, p. 201, doi. 10.1002/acn3.51269
By:
- Chahine, Lana M.;
- Brumm, Michael C.;
- Caspell‐Garcia, Chelsea;
- Oertel, Wolfgang;
- Mollenhauer, Brit;
- Amara, Amy;
- Fernandez‐Arcos, Ana;
- Tolosa, Eduardo;
- Simonet, Cristina;
- Hogl, Birgit;
- Videnovic, Aleksandar;
- Hutten, Samantha J.;
- Tanner, Caroline;
- Weintraub, Daniel;
- Burghardt, Elliot;
- Coffey, Christopher;
- Cho, Hyunkeun R.;
- Kieburtz, Karl;
- Poston, Kathleen L.;
- Merchant, Kalpana
Publication type:
Article
Longitudinal Measurements of Glucocerebrosidase activity in Parkinson's patients.
Published in:
Annals of Clinical & Translational Neurology, 2020, v. 7, n. 10, p. 1816, doi. 10.1002/acn3.51164
By:
- Alcalay, Roy N.;
- Wolf, Pavlina;
- Chiang, Ming Sum Ruby;
- Helesicova, Karolina;
- Zhang, Xiaokui Kate;
- Merchant, Kalpana;
- Hutten, Samantha J.;
- Scherzer, Clemens;
- Caspell‐Garcia, Chelsea;
- Blauwendraat, Cornelis;
- Foroud, Tatiana;
- Nudelman, Kelly;
- Gan‐Or, Ziv;
- Simuni, Tanya;
- Chahine, Lana M.;
- Levy, Oren;
- Zheng, Dandi;
- Li, Gen;
- Sardi, Sergio Pablo;
- Marek, Kenneth
Publication type:
Article
Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease.
Published in:
Annals of Clinical & Translational Neurology, 2020, v. 7, n. 4, p. 449, doi. 10.1002/acn3.51022
By:
- Weintraub, Daniel;
- Caspell‐Garcia, Chelsea;
- Simuni, Tanya;
- Cho, Hyunkeun R.;
- Coffey, Christopher S.;
- Aarsland, Dag;
- Alcalay, Roy N.;
- Barrett, Matthew J.;
- Chahine, Lana M.;
- Eberling, Jamie;
- Espay, Alberto J.;
- Hamilton, Jamie;
- Hawkins, Keith A.;
- Leverenz, James;
- Litvan, Irene;
- Richard, Irene;
- Rosenthal, Liana S.;
- Siderowf, Andrew;
- York, Michele
Publication type:
Article
The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort.
Published in:
Annals of Clinical & Translational Neurology, 2018, v. 5, n. 12, p. 1460, doi. 10.1002/acn3.644
By:
- Marek, Kenneth;
- Chowdhury, Sohini;
- Siderowf, Andrew;
- Lasch, Shirley;
- Coffey, Christopher S.;
- Caspell‐Garcia, Chelsea;
- Simuni, Tanya;
- Jennings, Danna;
- Tanner, Caroline M.;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Seibyl, John;
- Schuff, Norbert;
- Singleton, Andrew;
- Kieburtz, Karl;
- Toga, Arthur W.;
- Mollenhauer, Brit;
- Galasko, Doug;
- Chahine, Lana M.;
- Weintraub, Daniel
Publication type:
Article
Predictors of time to initiation of symptomatic therapy in early Parkinson's disease.
Published in:
Annals of Clinical & Translational Neurology, 2016, v. 3, n. 7, p. 482, doi. 10.1002/acn3.317
By:
- Simuni, Tanya;
- Long, Jeffrey D.;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher S.;
- Lasch, Shirley;
- Tanner, Caroline M.;
- Jennings, Danna;
- Kieburtz, Karl D.;
- Marek, Kenneth
Publication type:
Article
Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease.
Published in:
2020
By:
- Irwin, David J.;
- Fedler, Janel;
- Coffey, Christopher S.;
- Caspell‐Garcia, Chelsea;
- Kang, Ju Hee;
- Simuni, Tanya;
- Foroud, Tatiana;
- Toga, Arthur W.;
- Tanner, Caroline M.;
- Kieburtz, Karl;
- Chahine, Lana M.;
- Reimer, Alyssa;
- Hutten, Samantha;
- Weintraub, Daniel;
- Mollenhauer, Brit;
- Galasko, Douglas R.;
- Siderowf, Andrew;
- Marek, Kenneth;
- Trojanowski, John Q.;
- Shaw, Leslie M.
Publication type:
journal article
Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.
Published in:
2017
By:
- Eidson, Lori;
- Kannarkat, George;
- Barnum, Christopher;
- Chang, Jianjun;
- Chung, Jaegwon;
- Caspell-Garcia, Chelsea;
- Taylor, Peggy;
- Mollenhauer, Brit;
- Schlossmacher, Michael;
- Ereshefsky, Larry;
- Yen, Mark;
- Kopil, Catherine;
- Frasier, Mark;
- Marek, Kenneth;
- Hertzberg, Vicki;
- Tansey, Malú;
- Eidson, Lori N;
- Kannarkat, George T;
- Barnum, Christopher J;
- Schlossmacher, Michael G
Publication type:
journal article
Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study.
Published in:
2020
By:
- Simuni, Tanya;
- Brumm, Michael C.;
- Uribe, Liz;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher S.;
- Siderowf, Andrew;
- Alcalay, Roy N.;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Seibyl, John;
- Singleton, Andrew;
- Toga, Arthur W.;
- Galasko, Doug;
- Foroud, Tatiana;
- Nudelman, Kelly;
- Tosun‐Turgut, Duygu;
- Poston, Kathleen;
- Weintraub, Daniel;
- Mollenhauer, Brit;
- Tanner, Caroline M.
Publication type:
journal article
Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease.
Published in:
2019
By:
- Mollenhauer, Brit;
- Caspell‐Garcia, Chelsea J.;
- Coffey, Christopher S.;
- Taylor, Peggy;
- Singleton, Andy;
- Shaw, Leslie M.;
- Trojanowski, John Q.;
- Frasier, Mark;
- Simuni, Tanya;
- Iranzo, Alex;
- Oertel, Wolfgang;
- Siderowf, Andrew;
- Weintraub, Daniel;
- Seibyl, John;
- Toga, Arthur W.;
- Tanner, Caroline M.;
- Kieburtz, Karl;
- Chahine, Lana M.;
- Marek, Kenneth;
- Galasko, Douglas
Publication type:
journal article
CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.
Published in:
Acta Neuropathologica, 2016, v. 131, n. 6, p. 935, doi. 10.1007/s00401-016-1552-2
By:
- Kang, Ju-Hee;
- Mollenhauer, Brit;
- Coffey, Christopher;
- Toledo, Jon;
- Weintraub, Daniel;
- Galasko, Douglas;
- Irwin, David;
- Van Deerlin, Vivianna;
- Chen-Plotkin, Alice;
- Caspell-Garcia, Chelsea;
- Waligórska, Teresa;
- Taylor, Peggy;
- Shah, Nirali;
- Pan, Sarah;
- Zero, Pawel;
- Frasier, Mark;
- Marek, Kenneth;
- Kieburtz, Karl;
- Jennings, Danna;
- Tanner, Caroline
Publication type:
Article
Cognition among individuals along a spectrum of increased risk for Parkinson’s disease.
Published in:
PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201964
By:
- Chahine, Lana M.;
- Urbe, Liz;
- Caspell-Garcia, Chelsea;
- Aarsland, Dag;
- Alcalay, Roy;
- Barone, Paolo;
- Burn, David;
- Espay, Alberto J.;
- Hamilton, Jamie L.;
- Hawkins, Keith A.;
- Lasch, Shirley;
- Leverenz, James B.;
- Litvan, Irene;
- Richard, Irene;
- Siderowf, Andrew;
- Coffey, Christopher S.;
- Simuni, Tanya;
- Weintraub, Daniel;
- null, null
Publication type:
Article
Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort.
Published in:
2018
By:
- Simuni, Tanya;
- Siderowf, Andrew;
- Lasch, Shirley;
- Coffey, Chris S.;
- Caspell‐Garcia, Chelsea;
- Jennings, Danna;
- Tanner, Caroline M.;
- Trojanowski, John Q.;
- Shaw, Leslie M.;
- Seibyl, John;
- Schuff, Norbert;
- Singleton, Andrew;
- Kieburtz, Karl;
- Toga, Arthur W.;
- Mollenhauer, Brit;
- Galasko, Doug;
- Chahine, Lana M.;
- Weintraub, Daniel;
- Foroud, Tatiana;
- Tosun, Duygu
Publication type:
journal article
Motor and nonmotor heterogeneity of LRRK2-related and idiopathic Parkinson's disease.
Published in:
2016
By:
- Marras, Connie;
- Alcalay, Roy N.;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher;
- Chan, Piu;
- Duda, John E.;
- Facheris, Maurizio F.;
- Fernández‐Santiago, Rubén;
- Ruíz‐Martínez, Javier;
- Mestre, Tiago;
- Saunders‐Pullman, Rachel;
- Pont‐Sunyer, Claustre;
- Tolosa, Eduardo;
- Waro, Bjorg
Publication type:
journal article
Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study.
Published in:
Movement Disorders, 2015, v. 30, n. 10, p. 1371, doi. 10.1002/mds.26248
By:
- Simuni, Tanya;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher;
- Chahine, Lama M.;
- Lasch, Shirley;
- Oertel, Wolfgang H.;
- Mayer, Geert;
- Högl, Birgit;
- Postuma, Ron;
- Videnovic, Aleksandar;
- Amara, Amy Willis;
- Marek, Ken
Publication type:
Article
Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease.
Published in:
Movement Disorders, 2015, v. 30, n. 7, p. 919, doi. 10.1002/mds.26170
By:
- Weintraub, Daniel;
- Simuni, Tanya;
- Caspell‐Garcia, Chelsea;
- Coffey, Christopher;
- Lasch, Shirley;
- Siderowf, Andrew;
- Aarsland, Dag;
- Barone, Paolo;
- Burn, David;
- Chahine, Lama M.;
- Eberling, Jamie;
- Espay, Alberto J.;
- Foster, Eric D.;
- Leverenz, James B.;
- Litvan, Irene;
- Richard, Irene;
- Troyer, Matthew D.;
- Hawkins, Keith A.
Publication type:
Article
Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0175674
By:
- Caspell-Garcia, Chelsea;
- Simuni, Tanya;
- Tosun-Turgut, Duygu;
- Wu, I-Wei;
- Zhang, Yu;
- Nalls, Mike;
- Singleton, Andrew;
- Shaw, Leslie A.;
- Kang, Ju-Hee;
- Trojanowski, John Q.;
- Siderowf, Andrew;
- Coffey, Christopher;
- Lasch, Shirley;
- Aarsland, Dag;
- Burn, David;
- Chahine, Lana M.;
- Espay, Alberto J.;
- Foster, Eric D.;
- Hawkins, Keith A.;
- Litvan, Irene
Publication type:
Article

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