Works by Carrington, Mark

Results: 62

Distinct modes of interaction within eIF4F-like complexes and susceptibility to the RocA inhibitor for the Trypanosoma brucei EIF4AI translation initiation factor.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322812

By:

Moura, Danielle M. N.;
Soares, Amanda L.;
da Silva, Adalúcia;
Ribeiro, João L. A. B.;
Sunter, Jack D.;
Assis, Ludmila A.;
Carrington, Mark;
de Melo Neto, Osvaldo P.

Publication type:

Article

Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.88960

By:

Cook, Alexander D.;
Carrington, Mark;
Higgins, Matthew K.

Publication type:

Article

Ubiquitylation is Required for Degradation of Transmembrane Surface Proteins in Trypanosomes.

Published in:

Traffic, 2008, v. 9, n. 10, p. 1681, doi. 10.1111/j.1600-0854.2008.00785.x

By:

Wei-Lian Chung;
Ka Fai Leung;
Carrington, Mark;
Field, Mark C.

Publication type:

Article

Localization of serum resistance-associated protein in Trypanosoma brucei rhodesiense and transgenic Trypanosoma brucei brucei.

Published in:

Cellular Microbiology, 2015, v. 17, n. 10, p. 1523, doi. 10.1111/cmi.12454

By:

Bart, Jean‐Mathieu;
Cordon‐Obras, Carlos;
Vidal, Isabel;
Reed, Jennifer;
Perez‐Pastrana, Esperanza;
Cuevas, Laureano;
Field, Mark C.;
Carrington, Mark;
Navarro, Miguel

Publication type:

Article

TriTrypDB: a functional genomic resource for the Trypanosomatidae.

Published in:

Nucleic Acids Research, 2010, v. 38, p. D457, doi. 10.1093/nar/gkp851

By:

Aslett, Martin;
Aurrecoechea, Cristina;
Berriman, Matthew;
Brestelli, John;
Brunk, Brian P.;
Carrington, Mark;
Depledge, Daniel P.;
Fischer, Steve;
Gajria, Bindu;
Xin Gao;
Gardner, Malcolm J.;
Gingle, Alan;
Grant, Greg;
Harb, Omar S.;
Heiges, Mark;
Hertz-Fowler, Christiane;
Houston, Robin;
Innamorato, Frank;
Iodice, John;
Kissinger, Jessica C.

Publication type:

Article

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 10, p. 3374, doi. 10.1093/nar/gkn108

By:

Schwede, Angela;
Ellis, Louise;
Luther, Julia;
Carrington, Mark;
Stoecklin, Georg;
Clayton, Christine

Publication type:

Article

The two eIF4A helicases in Trypanosoma brucei are functionally distinct.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 9, p. 2495, doi. 10.1093/nar/gkl290

By:

Dhalia, Rafael;
Marinsek, Nina;
Reis, Christian R. S.;
Katz, Rodolfo;
Muniz, João R. C.;
Standart, Nancy;
Carrington, Mark;
de Melo Neto, Osvaldo P.

Publication type:

Article

Developmentally regulated instability of the GPI-PLC mRNA is dependent on a short-lived protein factor.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 5, p. 1503, doi. 10.1093/nar/gki298

By:

Webb, Helena;
Burns, Roisin;
Ellis, Louise;
Kimblin, Nicola;
Carrington, Mark

Publication type:

Article

The Ontology for Parasite Lifecycle (OPL): towards a consistent vocabulary of lifecycle stages in parasitic organisms.

Published in:

Journal of Biomedical Semantics, 2012, v. 3, n. 1, p. 5, doi. 10.1186/2041-1480-3-5

By:

Parikh, Priti P.;
Jie Zheng;
Logan-Klumpler, Flora;
Stoeckert Jr., Christian J.;
Louis, Christos;
Topalis, Pantelis;
Protasio, Anna V.;
Sheth, Amit P.;
Carrington, Mark;
Berriman, Matthew;
Sahoo, Satya S.

Publication type:

Article

The trypanosome flagellar pocket.

Published in:

Nature Reviews Microbiology, 2009, v. 7, n. 11, p. 775, doi. 10.1038/nrmicro2221

By:

Field, Mark C.;
Carrington, Mark

Publication type:

Article

How are Trypanosoma brucei receptors protected from host antibody‐mediated attack?

Published in:

BioEssays, 2024, v. 46, n. 7, p. 1, doi. 10.1002/bies.202400053

By:

Banerjee, Sourav;
Minshall, Nicola;
Webb, Helena;
Carrington, Mark

Publication type:

Article

An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.

Published in:

Genome Biology & Evolution, 2017, v. 9, n. 8, p. 2093, doi. 10.1093/gbe/evx152

By:

Kelly, Steven;
Ivens, Alasdair;
AdamMott, G.;
O'Neill, Ellis;
Emms, David;
Macleod, Olivia;
Voorheis, Paul;
Tyler, Kevin;
Clark, Matthew;
Matthews, Jacqueline;
Matthews, Keith;
Carrington, Mark

Publication type:

Article

A longitudinal two-year survey of the prevalence of trypanosomes in domestic cattle in Ghana by massively parallel sequencing of barcoded amplicons.

Published in:

PLoS Neglected Tropical Diseases, 2022, v. 16, n. 4, p. 1, doi. 10.1371/journal.pntd.0010300

By:

Ofori, Jennifer Afua;
Bakari, Soale Majeed;
Bah, Saikou;
Kolugu, Michael Kojo;
Aning, George Kwame;
Awandare, Gordon Akanzuwine;
Carrington, Mark;
Gwira, Theresa Manful

Publication type:

Article

Transmission of 'Candidatus Anaplasma camelii' to mice and rabbits by camel-specific keds, Hippobosca camelina.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 8, p. 1, doi. 10.1371/journal.pntd.0009671

By:

Bargul, Joel L.;
Kidambasi, Kevin O.;
Getahun, Merid N.;
Villinger, Jandouwe;
Copeland, Robert S.;
Muema, Jackson M.;
Carrington, Mark;
Masiga, Daniel K.

Publication type:

Article

How do trypanosomes change gene expression in response to the environment?

Published in:

Protoplasma, 2012, v. 249, n. 2, p. 223, doi. 10.1007/s00709-011-0282-5

By:

Schwede, Angela;
Kramer, Susanne;
Carrington, Mark

Publication type:

Article

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

Published in:

PLoS Pathogens, 2015, v. 11, n. 12, p. 1, doi. 10.1371/journal.ppat.1005259

By:

Schwede, Angela;
Macleod, Olivia J. S.;
MacGregor, Paula;
Carrington, Mark

Publication type:

Article

The isolation and characterization of genomic and cDNA clones coding for a cdc2-related kinase (ThCRK2) from the bovine protozoan parasite Theileria.

Published in:

Molecular Microbiology, 1996, v. 22, n. 2, p. 293, doi. 10.1046/j.1365-2958.1996.00124.x

By:

Kinnaird, Jane H.;
Logan, Mary;
Kirvar, Erol;
Tait, Andrew;
Carrington, Mark

Publication type:

Article

Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168074

By:

Biéler, Sylvain;
Waltenberger, Harald;
Barrett, Michael P.;
McCulloch, Richard;
Mottram, Jeremy C.;
Carrington, Mark;
Schwaeble, Wilhelm;
McKerrow, James;
Phillips, Margaret A.;
Michels, Paul A.;
Büscher, Philippe;
Sanchez, Jean-Charles;
Bishop, Richard;
Robinson, Derrick R.;
Bangs, James;
Ferguson, Michael;
Nerima, Barbara;
Albertini, Audrey;
Michel, Gerd;
Radwandska, Magdalena

Publication type:

Article

Sequencing 5‐Hydroxymethyluracil at Single‐Base Resolution.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 31, p. 9694, doi. 10.1002/anie.201804046

By:

Kawasaki, Fumiko;
Martínez Cuesta, Sergio;
Beraldi, Dario;
Mahtey, Areeb;
Hardisty, Robyn E.;
Carrington, Mark;
Balasubramanian, Shankar

Publication type:

Article

Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages.

Published in:

Molecular Microbiology, 2008, v. 69, n. 3, p. 666, doi. 10.1111/j.1365-2958.2008.06320.x

By:

Gluenz, Eva;
Sharma, Reuben;
Carrington, Mark;
Gull, Keith

Publication type:

Article

Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae.

Published in:

BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09591-z

By:

Albanaz, Amanda T. S.;
Carrington, Mark;
Frolov, Alexander O.;
Ganyukova, Anna I.;
Gerasimov, Evgeny S.;
Kostygov, Alexei Y.;
Lukeš, Julius;
Malysheva, Marina N.;
Votýpka, Jan;
Zakharova, Alexandra;
Záhonová, Kristína;
Zimmer, Sara L.;
Yurchenko, Vyacheslav;
Butenko, Anzhelika

Publication type:

Article

Sequencing 5‐Hydroxymethyluracil at Single‐Base Resolution.

Published in:

Angewandte Chemie, 2018, v. 130, n. 31, p. 9842, doi. 10.1002/ange.201804046

By:

Kawasaki, Fumiko;
Martínez Cuesta, Sergio;
Beraldi, Dario;
Mahtey, Areeb;
Hardisty, Robyn E.;
Carrington, Mark;
Balasubramanian, Shankar

Publication type:

Article

Multispecies reconstructions uncover widespread conservation, and lineage-specific elaborations in eukaryotic mRNA metabolism.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0192633

By:

Bannerman, Bridget P.;
Kramer, Susanne;
Dorrell, Richard G.;
Carrington, Mark

Publication type:

Article

Sugammadex: routine use vs restrictive use.

Published in:

British Journal of Hospital Medicine (17508460), 2020, v. 81, n. 6, p. 1, doi. 10.12968/hmed.2020.0014

By:

Ashiru, Gloria;
Carrington, Mark

Publication type:

Article

Proteomic Selection of Immunodiagnostic Antigens for Human African Trypanosomiasis and Generation of a Prototype Lateral Flow Immunodiagnostic Device.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 2, p. 1, doi. 10.1371/journal.pntd.0002087

By:

Sullivan, Lauren;
Wall, Steven J.;
Carrington, Mark;
Ferguson, Michael A. J.

Publication type:

Article

Proteomic Selection of Immunodiagnostic Antigens for Human African Trypanosomiasis and Generation of a Prototype Lateral Flow Immunodiagnostic Device.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 2, p. 1, doi. 10.1371/journal.pntd.0002087

By:

Sullivan, Lauren;
Wall, Steven J.;
Carrington, Mark;
Ferguson, Michael A. J.

Publication type:

Article

Murine Models for Trypanosoma brucei gambiense Disease Progression--From Silent to Chronic Infections and Early Brain Tropism.

Published in:

PLoS Neglected Tropical Diseases, 2009, v. 3, n. 9, p. 1, doi. 10.1371/journal.pntd.0000509

By:

Giroud, Christiane;
Ottones, Florence;
Coustou, Virginie;
Dacheux, Denis;
Biteau, Nicolas;
Miezan, Benjamin;
Reet, Nick Van;
Carrington, Mark;
Doua, Felix;
Baltz, Theéo

Publication type:

Article

Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications.

Published in:

RNA Biology, 2017, v. 14, n. 5, p. 611, doi. 10.1080/15476286.2015.1137422

By:

Cording, Amy;
Gormally, Michael;
Bond, Peter J.;
Carrington, Mark;
Balasubramanian, Shankar;
Miska, Eric A.;
Thomas, Beth

Publication type:

Article

Two related trypanosomatid eIF4G homologues have functional differences compatible with distinct roles during translation initiation.

Published in:

RNA Biology, 2015, v. 12, n. 3, p. 305, doi. 10.1080/15476286.2015.1017233

By:

Moura, Danielle MN;
Reis, Christian RS;
Xavier, Camila C;
da Costa Lima, Tamara D;
Lima, Rodrigo P;
Carrington, Mark;
de Melo Neto, Osvaldo P

Publication type:

Article

AU-rich instability element found responsible for DHHl-induced mRNA stabilization.

Published in:

RNA Biology, 2014, v. 11, n. 6, p. 2

By:

Kramer, Susanne;
Carrington, Mark

Publication type:

Article

Landes Highlights.

Published in:

RNA Biology, 2014, v. 11, n. 5, p. 667

By:

Turner, Michael J.;
Jiao, Alan L.;
Slack, Frank J.;
Anton, Tobias;
Bultmann, Sebastian;
Leonhardt, Heinrich;
Markaki, Yolanda;
Kramer, Susanne;
Carrington, Mark;
Hong Yang;
Rao, Jaladanki N.;
Jian-Ying Wang

Publication type:

Article

VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins.

Published in:

BMC Bioinformatics, 2007, v. 8, p. 143, doi. 10.1186/1471-2105-8-143

By:

Marcello, Lucio;
Menon, Suraj;
Ward, Pauline;
Wilkes, Jonathan M;
Jones, Nicola G;
Carrington, Mark;
Barry, J David

Publication type:

Article

Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 16, p. 8013, doi. 10.1093/nar/gkv731

By:

Fritz, Melanie;
Vanselow, Jens;
Sauer, Nadja;
Lamer, Stephanie;
Goos, Carina;
Siegel, T. Nicolai;
Subota, Ines;
Schlosser, Andreas;
Carrington, Mark;
Kramer, Susanne

Publication type:

Article

A short RNA stem–loop is necessary and sufficient for repression of gene expression during early logarithmic phase in trypanosomes.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 11, p. 7201, doi. 10.1093/nar/gku358

By:

Fernández-Moya, Sandra M.;
Carrington, Mark;
Estévez, Antonio M.

Publication type:

Article

Determinants of GPI-PLC Localisation to the Flagellum and Access to GPI-Anchored Substrates in Trypanosomes.

Published in:

PLoS Pathogens, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.ppat.1003566

By:

Sunter, Jack;
Webb, Helena;
Carrington, Mark

Publication type:

Article

The Glycosylphosphatidylinositol-PLC in Trypanosoma brucei Forms a Linear Array on the Exterior of the Flagellar Membrane Before and After Activation.

Published in:

PLoS Pathogens, 2009, v. 5, n. 6, p. 1, doi. 10.1371/journal.ppat.1000468

By:

Hanrahan, Orla;
Webb, Helena;
O'Byrne, Robert;
Brabazon, Elaine;
Treumann, Achim;
Sunter, Jack D.;
Carrington, Mark;
Voorheis, H. Paul

Publication type:

Article

Intracellular Membrane Transport Systems inTrypanosoma brucei.

Published in:

Traffic, 2004, v. 5, n. 12, p. 905, doi. 10.1111/j.1600-0854.2004.00234.x

By:

Field, Mark C.;
Carrington, Mark

Publication type:

Article

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15125-y

By:

Macleod, Olivia J. S.;
Bart, Jean-Mathieu;
MacGregor, Paula;
Peacock, Lori;
Savill, Nicholas J.;
Hester, Svenja;
Ravel, Sophie;
Sunter, Jack D.;
Trevor, Camilla;
Rust, Steven;
Vaughan, Tristan J.;
Minter, Ralph;
Mohammed, Shabaz;
Gibson, Wendy;
Taylor, Martin C.;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article

Correction: Murine Models for Trypanosoma brucei gambiense Disease Progression—From Silent to Chronic Infections and Early Brain Tropism.

Published in:

2016

By:

Giroud, Christiane;
Ottones, Florence;
Coustou, Virginie;
Dacheux, Denis;
Biteau, Nicolas;
Miezan, Benjamin;
Van Reet, Nick;
Carrington, Mark;
Doua, Felix;
Baltz, Théo

Publication type:

Correction Notice

Depletion of the RNA-Binding Protein RBP33 Results in Increased Expression of Silenced RNA Polymerase II Transcripts in Trypanosoma brucei.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107608

By:

Fernández-Moya, Sandra M.;
Carrington, Mark;
Estévez, Antonio M.

Publication type:

Article

Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054004

By:

Kramer, Susanne;
Bannerman-Chukualim, Bridget;
Ellis, Louise;
Boulden, Elizabeth A.;
Kelly, Steve;
Field, Mark C.;
Carrington, Mark

Publication type:

Article

Alterations in DRBD3 Ribonucleoprotein Complexes in Response to Stress in Trypanosoma brucei.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048870

By:

Fernÿndez-Moya, Sandra M.;
García-Pérez, Angélica;
Kramer, Susanne;
Carrington, Mark;
Estévez, Antonio M.

Publication type:

Article

A New Generation of T7 RNA Polymerase-Independent Inducible Expression Plasmids for Trypanosoma brucei.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035167

By:

Sunter, Jack;
Wickstead, Bill;
Gull, Keith;
Carrington, Mark

Publication type:

Article

The Orthologue of Sjögren's Syndrome Nuclear Autoantigen 1 (SSNA1) in Trypanosoma brucei Is an Immunogenic Self-Assembling Molecule.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031842

By:

Price, Helen P.;
Hodgkinson, Michael R.;
Curwen, Rachel S.;
MacLean, Lorna M.;
Brannigan, James A.;
Carrington, Mark;
Smith, Barbara A.;
Ashford, David A.;
Stark, Meg;
Smith, Deborah F.

Publication type:

Article

Is There a Classical Nonsense-Mediated Decay Pathway in Trypanosomes?

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025112

By:

Delhi, Praveen;
Queiroz, Rafael;
Inchaustegui, Diana;
Carrington, Mark;
Clayton, Christine

Publication type:

Article

Chaperone Requirements for Biosynthesis of the Trypanosome Variant Surface Glycoprotein.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008468

By:

Field, Mark C.;
Sergeenko, Tatiana;
Ya-Nan Wang;
Böhm, Susanne;
Carrington, Mark

Publication type:

Article

Blocking Variant Surface Glycoprotein Synthesis in Trypanosoma brucei Triggers a General Arrest in Translation Initiation.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007532

By:

Smith, Terry K.;
Vasileva, Nadina;
Gluenz, Eva;
Terry, Stephen;
Portman, Neil;
Kramer, Susanne;
Carrington, Mark;
Michaeli, Shulamit;
Gull, Keith;
Rudenko, Gloria

Publication type:

Article

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13044

By:

Lane-Serff, Harriet;
MacGregor, Paula;
Peacock, Lori;
Macleod, Olivia J. S.;
Kay, Christopher;
Gibson, Wendy;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article

A unique mRNA decapping complex in trypanosomes.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 14, p. 7520, doi. 10.1093/nar/gkad497

By:

Kramer, Susanne;
Karolak, Natalia Katarzyna;
Odenwald, Johanna;
Gabiatti, Bernardo;
Castañeda Londoño, Paula Andrea;
Zavřelová, Anna;
Freire, Eden Ribeiro;
Almeida, Kayo Schemiko;
Braune, Silke;
Moreira, Claudia;
Eder, Amelie;
Goos, Carina;
Field, Mark;
Carrington, Mark;
Holetz, Fabiola;
Górna, Maria Wiktoria;
Zoltner, Martin

Publication type:

Article

Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32728-9

By:

Macleod, Olivia J. S.;
Cook, Alexander D.;
Webb, Helena;
Crow, Mandy;
Burns, Roisin;
Redpath, Maria;
Seisenberger, Stefanie;
Trevor, Camilla E.;
Peacock, Lori;
Schwede, Angela;
Kimblin, Nicola;
Francisco, Amanda F.;
Pepperl, Julia;
Rust, Steve;
Voorheis, Paul;
Gibson, Wendy;
Taylor, Martin C.;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article