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The antitumor effect induced by an IL-2 'no-alpha' mutein depends on changes in the CD8<sup>+</sup> T lymphocyte/Treg cell balance.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.974188
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- Article
Directed evolution of super-secreted variants from phage-displayed human Interleukin-2.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37280-5
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- Article
Purified Capsular Polysaccharide of Neisseria meningitidis Serogroup A as Immune Potentiator for Antibody Production.
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- Current Microbiology, 2010, v. 60, n. 2, p. 79, doi. 10.1007/s00284-009-9505-9
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- Article
Mathematical Models of the impact of IL2 modulation therapies on T cell dynamics.
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- Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00439
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- Article
Molecular dissection of the interactions of an antitumor interleukin-2-derived mutein on a phage display-based platform.
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- Journal of Molecular Recognition, 2015, v. 28, n. 4, p. 261, doi. 10.1002/jmr.2440
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- Article
Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05188-0
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- Article