OpenURL Connection Search

Select item for more details and to access through your institution.

Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis.
Published in:
FASEB Bioadvances, 2019, v. 1, n. 4, p. 246, doi. 10.1096/fba.2018-00048
By:
- Burke, Christopher;
- Abrahams, Katherine A.;
- Richardson, Emily J.;
- Loman, Nicholas J.;
- Alemparte, Carlos;
- Lelievre, Joel;
- Besra, Gurdyal S.
Publication type:
Article
Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.
Published in:
Scientific Reports, 2016, p. 38986, doi. 10.1038/srep38986
By:
- Cox, Jonathan A. G.;
- Mugumbate, Grace;
- Del Peral, Laura Vela-Glez;
- Jankute, Monika;
- Abrahams, Katherine A.;
- Jervis, Peter;
- Jackenkroll, Stefan;
- Perez, Arancha;
- Alemparte, Carlos;
- Esquivias, Jorge;
- Lelièvre, Joël;
- Ramon, Fernando;
- Barros, David;
- Ballell, Lluis;
- Besra, Gurdyal S.
Publication type:
Article
Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113568
By:
- Gurcha, Sudagar S.;
- Usha, Veeraraghavan;
- Cox, Jonathan A. G.;
- Fütterer, Klaus;
- Abrahams, Katherine A.;
- Bhatt, Apoorva;
- Alderwick, Luke J.;
- Reynolds, Robert C.;
- Loman, Nicholas J.;
- Nataraj, VijayaShankar;
- Alemparte, Carlos;
- Barros, David;
- Lloyd, Adrian J.;
- Ballell, Lluis;
- Hobrath, Judith V.;
- Besra, Gurdyal S.
Publication type:
Article
Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060933
By:
- Remuiñán, Modesto J.;
- Pérez-Herrán, Esther;
- Rullás, Joaquín;
- Alemparte, Carlos;
- Martínez-Hoyos, María;
- Dow, David J.;
- Afari, Johnson;
- Mehta, Nalini;
- Esquivias, Jorge;
- Jiménez, Elena;
- Ortega-Muro, Fátima;
- Fraile-Gabaldón, María Teresa;
- Spivey, Vickey L.;
- Loman, Nicholas J.;
- Pallen, Mark J.;
- Constantinidou, Chrystala;
- Minick, Douglas J.;
- Cacho, Mónica;
- Rebollo-López, María José;
- González, Carolina
Publication type:
Article
Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052951
By:
- Abrahams, Katherine A.;
- Cox, Jonathan A. G.;
- Spivey, Vickey L.;
- Loman, Nicholas J.;
- Pallen, Mark J.;
- Constantinidou, Chrystala;
- Fernández, Raquel;
- Alemparte, Carlos;
- Remuiñán, Modesto J.;
- Barros, David;
- Ballell, Lluis;
- Besra, Gurdyal S.
Publication type:
Article
Direct Organocatalytic and Highly Enantio- and Diastereoselective Mannich Reactions of α-Substituted α-CyanoacetatesThis work was made possible by a grant from The Danish National Research Foundation. We are grateful to Dr. Jacob Overgaard for X-ray crystallographic analysis.
Published in:
Angewandte Chemie, 2005, v. 117, n. 19, p. 2956, doi. 10.1002/ange.200500144
By:
- Thomas B. Poulsen;
- Carlos Alemparte;
- Steen Saaby;
- Marco Bella;
- Karl Anker Jørgensen
Publication type:
Article
Direct Organocatalytic and Highly Enantio- and Diastereoselective Mannich Reactions of α-Substituted α-CyanoacetatesThis work was made possible by a grant from The Danish National Research Foundation. We are grateful to Dr. Jacob Overgaard for X-ray crystallographic analysis.
Published in:
Angewandte Chemie International Edition, 2005, v. 44, n. 19, p. 2896, doi. 10.1002/anie.200500144
By:
- Thomas B. Poulsen;
- Carlos Alemparte;
- Steen Saaby;
- Marco Bella;
- Karl Anker Jørgensen
Publication type:
Article

Found: 7

Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis.

Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.

Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target.

Tetrahydropyrazolo[1,5-<i>a</i>]Pyrimidine-3-Carboxamide and <i>N</i>-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-<i>c</i>]Pyran] Analogues with Bactericidal Efficacy against <i>Mycobacterium tuberculosis</i> Targeting MmpL3.

Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB.

Direct Organocatalytic and Highly Enantio- and Diastereoselective Mannich Reactions of α-Substituted α-CyanoacetatesThis work was made possible by a grant from The Danish National Research Foundation. We are grateful to Dr. Jacob Overgaard for X-ray crystallographic analysis.

Direct Organocatalytic and Highly Enantio- and Diastereoselective Mannich Reactions of α-Substituted α-CyanoacetatesThis work was made possible by a grant from The Danish National Research Foundation. We are grateful to Dr. Jacob Overgaard for X-ray crystallographic analysis.