Works by Cappola, Thomas P.

Results: 33

Klf15 Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation.

Published in:

Science Translational Medicine, 2010, v. 2, n. 26, p. 1, doi. 10.1126/scitranslmed.3000502

By:

Haldar, Saptarsi M.;
Yuan Lu;
Jeyaraj, Darwin;
Kawanami, Daiji;
Yingjie Cui;
Eapen, Sam J.;
Hao, Caili;
Yan Li;
Yong-Qiu Doughman;
Watanabe, Michiko;
Shimizu, Koichi;
Kuivaniemi, Helena;
Sadoshima, Junichi;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Jain, Mukesh K.

Publication type:

Article

Association of An Intronic, but Not Any Exonic, FRMD4B Sequence Variant and Heart Failure.

Published in:

CTS: Clinical & Translational Science, 2010, v. 3, n. 4, p. 134, doi. 10.1111/j.1752-8062.2010.00220.x

By:

Matkovich, Scot J.;
Van Booven, Derek J.;
Cappola, Thomas P.;
Dorn II, Gerald W.

Publication type:

Article

GLP-1 Receptor Expression Within the Human Heart.

Published in:

Endocrinology, 2018, v. 159, n. 4, p. 1570, doi. 10.1210/en.2018-00004

By:

Baggio, Laurie L;
Yusta, Bernardo;
Mulvihill, Erin E;
Cao, Xiemin;
Streutker, Catherine J;
Butany, Jagdish;
Cappola, Thomas P;
Margulies, Kenneth B;
Drucker, Daniel J

Publication type:

Article

Myocardin regulates BMP10 expression and is required for heart development.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 1, doi. 10.1172/JCI63635

By:

Jianhe Huang;
Elicker, John;
Bowens, Nina;
Xi Liu;
Lan Cheng;
Cappola, Thomas P.;
Xiaohong Zhu;
Parmacek, Michael S.

Publication type:

Article

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.

Published in:

2010

By:

Matkovich, Scot J.;
Van Booven, Derek J.;
Hindes, Anna;
Mm Young Kang;
Druley, Todd E.;
Vallania, Francesco L. M.;
Mitra, Robi D.;
Reilly, Muredach P.;
Cappola, Thomas P.;
Dorn II, Gerald W.;
Kang, Min Young;
Dorn, Gerald W 2nd

Publication type:

journal article

Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study).

Published in:

2018

By:

Tereshchenko, Larisa G.;
Sotoodehnia, Nona;
Sitlani, Colleen M.;
Ashar, Foram N.;
Kabir, Muammar;
Biggs, Mary L.;
Morley, Michael P.;
Waks, Jonathan W.;
Soliman, Elsayed Z.;
Buxton, Alfred E.;
Biering-Sørensen, Tor;
Solomon, Scott D.;
Post, Wendy S.;
Cappola, Thomas P.;
Siscovick, David S.;
Arking, Dan E.

Publication type:

journal article

Heart Failure, Left Ventricular Remodeling, and Circulating Nitric Oxide Metabolites.

Published in:

Journal of the American Heart Association, 2016, v. 5, n. 10, p. 1, doi. 10.1161/JAHA.116.004133

By:

Chirinos, Julio A.;
Akers, Scott R.;
Trieu, Lien;
Ischiropoulos, Harry;
Doulias, Paschalis‐Thomas;
Tariq, Ali;
Vasim, Izzah;
Koppula, Maheswara R.;
Syed, Amer Ahmed;
Soto‐Calderon, Haideliza;
Townsend, Raymond R.;
Cappola, Thomas P.;
Margulies, Kenneth B.;
Zamani, Payman

Publication type:

Article

Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure.

Published in:

2014

By:

Zhang, Kathleen W;
French, Benjamin;
May Khan, Abigail;
Plappert, Ted;
Fang, James C;
Sweitzer, Nancy K;
Borlaug, Barry A;
Chirinos, Julio A;
St John Sutton, Martin;
Cappola, Thomas P;
Ky, Bonnie

Publication type:

journal article

Effects of organic and inorganic nitrate on aortic and carotid haemodynamics in heart failure with preserved ejection fraction.

Published in:

European Journal of Heart Failure. Supplements, 2017, v. 19, n. 11, p. 1507, doi. 10.1002/ejhf.885

By:

Chirinos, Julio A.;
Londono-Hoyos, Francisco;
Zamani, Payman;
Beraun, Melissa;
Haines, Philip;
Vasim, Izzah;
Varakantam, Swapna;
Phan, Timothy S.;
Cappola, Thomas P.;
Margulies, Kenneth B.;
Townsend, Raymond R.;
Segers, Patrick

Publication type:

Article

Supercomputing for the parallelization of whole genome analysis.

Published in:

Bioinformatics, 2014, v. 30, n. 11, p. 1508, doi. 10.1093/bioinformatics/btu071

By:

Puckelwartz, Megan J.;
Pesce, Lorenzo L.;
Nelakuditi, Viswateja;
Dellefave-Castillo, Lisa;
Golbus, Jessica R.;
Day, Sharlene M.;
Cappola, Thomas P.;
Dorn, Gerald W.;
Foster, Ian T.;
McNally, Elizabeth M.

Publication type:

Article

42855 A Phenomics Approach to the Categorization and Refinement of Heart Failure.

Published in:

2021

By:

Reza, Nosheen;
Bone, William;
Singhal, Pankhuri;
Verma, Anurag;
Murthy, Ashwin C.;
Denduluri, Srinivas;
Adusumalli, Srinath;
Ritchie, Macrylyn D.;
Cappola, Thomas P.

Publication type:

Abstract

MetaDiff: differential isoform expression analysis using random-effects meta-regression.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0623-z

By:

Cheng Jia;
Weihua Guan;
Yang, Amy;
Rui Xiao;
Tang, W. H. Wilson;
Moravec, Christine S.;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Chun Li;
Mingyao Li

Publication type:

Article

MetaDiff: differential isoform expression analysis using random-effects meta-regression.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0623-z

By:

Cheng Jia;
Weihua Guan;
Amy Yang;
Rui Xiao;
Wilson Tang, W. H.;
Moravec, Christine S.;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Mingyao Li;
Chun Li

Publication type:

Article

MetaDiff: differential isoform expression analysis using random-effects meta-regression.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0623-z

By:

Cheng Jia;
Weihua Guan;
Yang, Amy;
Rui Xiao;
Wilson Tang, W. H.;
Moravec, Christine S.;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Mingyao Li;
Chun Li

Publication type:

Article

MetaDiff: differential isoform expression analysis using random-effects meta-regression

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 208, doi. 10.1186/s12859-015-0623-z

By:

Cheng Jia;
Weihua Guan;
Amy Yang;
Rui Xiao;
Tang, W. H. Wilson;
Moravec, Christine S.;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Mingyao Li;
Chun Li

Publication type:

Article

Bayesian integration of genetics and epigenetics detects causal regulatory SNPs underlying expression variability.

Published in:

Nature Communications, 2015, v. 6, n. 10, p. 8555, doi. 10.1038/ncomms9555

By:

Das, Avinash;
Morley, Michael;
Moravec, Christine S.;
Tang, W. H. W.;
Hakonarson, Hakon;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Jensen, Shane;
Hannenhalli, Sridhar

Publication type:

Article

Development and evaluation of multi-marker risk scores for clinical prognosis.

Published in:

2016

By:

French, Benjamin;
Saha-Chaudhuri, Paramita;
Ky, Bonnie;
Cappola, Thomas P.;
Heagerty, Patrick J.

Publication type:

journal article

Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac pathology and early indicators of cardiac risk.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01854-8

By:

Tan, Konstanze;
Tay, Darwin;
Tan, Wilson;
Ng, Hong Kiat;
Wong, Eleanor;
Morley, Michael P.;
Singhera, Gurpreet K.;
Lee, Chang Jie Mick;
Jain, Pritesh R.;
Tai, Fei Li;
Hanson, Paul J.;
Cappola, Thomas P.;
Margulies, Kenneth B.;
Foo, Roger;
Loh, Marie

Publication type:

Article

Mental Stress-Induced Myocardial Ischemia: When the Mind Controls the Fate of the Heart.

Published in:

2021

By:

Bravo, Paco E.;
Cappola, Thomas P.

Publication type:

Editorial

Recreational Exercise in Hypertrophic Cardiomyopathy.

Published in:

2017

By:

Owens, Anjali T.;
Cappola, Thomas P.

Publication type:

Editorial

Lack of Benefit for Liraglutide in Heart Failure-Reply.

Published in:

2016

By:

Margulies, Kenneth B.;
McNulty, Steven E.;
Cappola, Thomas P.

Publication type:

Letter

Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.

Published in:

2016

By:

Margulies, Kenneth B.;
Hernandez, Adrian F.;
Redfield, Margaret M.;
Givertz, Michael M.;
Oliveira, Guilherme H.;
Cole, Robert;
Mann, Douglas L.;
Whellan, David J.;
Kiernan, Michael S.;
Felker, G. Michael;
McNulty, Steven E.;
Anstrom, Kevin J.;
Shah, Monica R.;
Braunwald, Eugene;
Cappola, Thomas P.;
NHLBI Heart Failure Clinical Research Network

Publication type:

journal article

Gene Profiling of Human Adipose Tissue During Evoked Inflammation In Vivo.

Published in:

Diabetes, 2009, v. 58, n. 10, p. 2211, doi. 10.2337/db09-0256

By:

Shah, Rachana;
Lu, Yun;
Hinkle, Christine C.;
McGillicuddy, Fiona C.;
Kim, Roy;
Hannenhalli, Sridhar;
Cappola, Thomas P.;
Heffron, Sean;
Wang, XingMei;
Mehta, Nehal N.;
Putt, Mary;
Reilly, Muredach P.

Publication type:

Article

Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms.

Published in:

Nature, 2002, v. 416, n. 6878, p. 337, doi. 10.1038/416337a

By:

Barouch, Lili A.;
Harrison, Robert W.;
Skaf, Michael W.;
Rosas, Gisele O.;
Cappola, Thomas P.;
Kobeissi, Zoulficart A.;
Hobal, Ion A.;
Lemmon, Christopher A.;
Burnett, Arthur L.;
O'Rourke, Brian;
Rodriguez, E. Rene;
Huang, Paul L.;
Lima, João A.C.;
Berkowitz, Dan E.;
Hare, Joshua M.

Publication type:

Article

Diversifying the Genetic Landscape of Heart Disease.

Published in:

JAMA: Journal of the American Medical Association, 2023, v. 330, n. 5, p. 415, doi. 10.1001/jama.2023.12375

By:

Tcheandjieu, Catherine;
Cappola, Thomas P.

Publication type:

Article

The Prognostic Value of Plasma Soluble ST2 in Hospitalized Chinese Patients with Heart Failure.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110976

By:

Zhang, Rongcheng;
Zhang, Yuhui;
Zhang, Jian;
An, Tao;
Huang, Yan;
Guo, Xiao;
Januzzi, James L.;
Cappola, Thomas P.;
Yin, Shijie;
Wang, Yunhong;
Zhou, Qiong;
Zou, Changhong;
Ji, Shiming;
Lv, Rong

Publication type:

Article

Non-Iterative, Regression-Based Estimation of Haplotype Associations with Censored Survival Outcomes.

Published in:

Statistical Applications in Genetics & Molecular Biology, 2012, v. 11, n. 3, p. 1, doi. 10.1515/1544-6115.1764

By:

French, Benjamin;
Lumley, Thomas;
Cappola, Thomas P.;
Mitra, Nandita

Publication type:

Article

Effects of organic and inorganic nitrate on aortic and carotid haemodynamics in heart failure with preserved ejection fraction.

Published in:

2017

By:

Chirinos, Julio A.;
Londono ‐ Hoyos, Francisco;
Zamani, Payman;
Beraun, Melissa;
Haines, Philip;
Vasim, Izzah;
Varakantam, Swapna;
Phan, Timothy S.;
Cappola, Thomas P.;
Margulies, Kenneth B.;
Townsend, Raymond R.;
Segers, Patrick;
Londono-Hoyos, Francisco

Publication type:

journal article

Influence of renal dysfunction phenotype on mortality in the setting of cardiac dysfunction: analysis of three randomized controlled trials.

Published in:

European Journal of Heart Failure, 2011, v. 13, n. 11, p. 1224, doi. 10.1093/eurjhf/hfr123

By:

Testani, Jeffrey M.;
Coca, Steven G.;
Shannon, Richard P.;
Kimmel, Stephen E.;
Cappola, Thomas P.

Publication type:

Article

Truncated titin proteins in dilated cardiomyopathy.

Published in:

Science Translational Medicine, 2021, v. 13, n. 618, p. 1, doi. 10.1126/scitranslmed.abd7287

By:

McAfee, Quentin;
Chen, Christina Yingxian;
Yang, Yifan;
Caporizzo, Matthew A.;
Morley, Michael;
Babu, Apoorva;
Jeong, Sunhye;
Brandimarto, Jeffrey;
Bedi Jr, Kenneth C.;
Flam, Emily;
Cesare, Joseph;
Cappola, Thomas P.;
Margulies, Kenneth;
Prosser, Benjamin;
Arany, Zolt

Publication type:

Article

Sparse Simultaneous Signal Detection for Identifying Genetically Controlled Disease Genes.

Published in:

Journal of the American Statistical Association, 2017, v. 112, n. 519, p. 1032, doi. 10.1080/01621459.2016.1270825

By:

Zhao, Sihai Dave;
Cai, T. Tony;
Cappola, Thomas P.;
Margulies, Kenneth B.;
Li, Hongzhe

Publication type:

Article

Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23.

Published in:

European Heart Journal, 2021, v. 42, n. 20, p. 2000, doi. 10.1093/eurheartj/ehab030

By:

Garnier, Sophie;
Harakalova, Magdalena;
Weiss, Stefan;
Mokry, Michal;
Regitz-Zagrosek, Vera;
Hengstenberg, Christian;
Cappola, Thomas P;
Isnard, Richard;
Arbustini, Eloisa;
Cook, Stuart A;
Setten, Jessica van;
Calis, Jorg J A;
Hakonarson, Hakon;
Morley, Michael P;
Stark, Klaus;
Prasad, Sanjay K;
Li, Jin;
O'Regan, Declan P;
Grasso, Maurizia;
Müller-Nurasyid, Martina

Publication type:

Article

Reciprocal regulation of metabolic and signaling pathways.

Published in:

BMC Genomics, 2010, v. 11, p. 197, doi. 10.1186/1471-2164-11-197

By:

Barth, Andreas S.;
Kumordzie, Ami;
Colantuoni, Carlo;
Margulies, Kenneth B.;
Cappola, Thomas P.;
Tomaselli, Gordon F.

Publication type:

Article