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From genetic mosaicism to tumorigenesis through indirect genetic effects.
- Published in:
- BioEssays, 2024, v. 46, n. 7, p. 1, doi. 10.1002/bies.202300238
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- Publication type:
- Article
Genomic and metabolic instability during long-term fermentation of an industrial Saccharomyces cerevisiae strain engineered for C5 sugar utilization.
- Published in:
- Frontiers in Bioengineering & Biotechnology, 2024, p. 1, doi. 10.3389/fbioe.2024.1357671
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- Publication type:
- Article
The impact of food availability on tumorigenesis is evolutionarily conserved.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-46896-1
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- Publication type:
- Article
The Ins and Outs of Endosteal Niche Disruption in the Bone Marrow: Relevance for Myeloma Oncogenesis.
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- Biology (2079-7737), 2023, v. 12, n. 7, p. 990, doi. 10.3390/biology12070990
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- Publication type:
- Article
The paradox of cooperation among selfish cancer cells.
- Published in:
- Evolutionary Applications, 2023, v. 16, n. 7, p. 1239, doi. 10.1111/eva.13571
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- Publication type:
- Article
From developmental to atavistic bet‐hedging: How cancer cells pervert the exploitation of random single‐cell phenotypic fluctuations.
- Published in:
- BioEssays, 2022, v. 44, n. 9, p. 1, doi. 10.1002/bies.202200048
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- Publication type:
- Article
Bridging Tumorigenesis and Therapy Resistance With a Non-Darwinian and Non-Lamarckian Mechanism of Adaptive Evolution.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.732081
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- Publication type:
- Article
Editorial: Non-Genetic Heterogeneity in Development and Disease.
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- 2021
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- Publication type:
- Editorial
Is There One Key Step in the Metastatic Cascade?
- Published in:
- Cancers, 2021, v. 13, n. 15, p. 3693, doi. 10.3390/cancers13153693
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- Publication type:
- Article
Does Cancer Biology Rely on Parrondo's Principles?
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- Cancers, 2021, v. 13, n. 9, p. 2197, doi. 10.3390/cancers13092197
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- Publication type:
- Article
This is the theory – Response to Tez on the origins of paediatric cancers (https://doi.org/10.1002/bies.202000324).
- Published in:
- BioEssays, 2021, v. 43, n. 4, p. 1, doi. 10.1002/bies.202100016
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- Publication type:
- Article
Identifying key questions in the ecology and evolution of cancer.
- Published in:
- Evolutionary Applications, 2021, v. 14, n. 4, p. 877, doi. 10.1111/eva.13190
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- Publication type:
- Article
Interplay between genetic, epigenetic, and gene expression variability: Considering complexity in evolvability.
- Published in:
- Evolutionary Applications, 2021, v. 14, n. 4, p. 893, doi. 10.1111/eva.13204
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- Publication type:
- Article
Group phenotypic composition in cancer.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.63518
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- Publication type:
- Article
Tissue‐disruption‐induced cellular stochasticity and epigenetic drift: Common origins of aging and cancer?
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- BioEssays, 2021, v. 43, n. 1, p. 1, doi. 10.1002/bies.202000140
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- Publication type:
- Article
SIR2 Expression Noise Can Generate Heterogeneity in Viability but Does Not Affect Cell-to-Cell Epigenetic Silencing of Subtelomeric URA3 in Yeast.
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- G3: Genes | Genomes | Genetics, 2020, v. 10, n. 9, p. 1, doi. 10.1534/g3.120.401589
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- Publication type:
- Article
Multiple Myeloma as a Bone Disease? The Tissue Disruption-Induced Cell Stochasticity (TiDiS) Theory.
- Published in:
- Cancers, 2020, v. 12, n. 8, p. 2158, doi. 10.3390/cancers12082158
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- Publication type:
- Article
Cancer Stem Cells: From Historical Roots to a New Perspective.
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- Journal of Oncology, 2019, p. 1, doi. 10.1155/2019/5189232
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- Publication type:
- Article
Gene Expression Noise Produces Cell-to-Cell Heterogeneity in Eukaryotic Homologous Recombination Rate.
- Published in:
- Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00475
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- Publication type:
- Article
Differences in mutational processes and intra-tumour heterogeneity between organs: The local selective filter hypothesis.
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- Evolution, Medicine & Public Health, 2019, v. 2019, n. 1, p. 139, doi. 10.1093/emph/eoz017
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- Publication type:
- Article
A GRX1 Promoter Variant Confers Constitutive Noisy Bimodal Expression That Increases Oxidative Stress Resistance in Yeast.
- Published in:
- Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02158
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- Publication type:
- Article
Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event.
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- Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00355
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- Publication type:
- Article
Tissue disruption increases stochastic gene expression thus producing tumors: Cancer initiation without driver mutation.
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- International Journal of Cancer, 2017, v. 140, n. 11, p. 2408, doi. 10.1002/ijc.30596
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- Publication type:
- Article
Use of noise in gene expression as an experimental parameter to test phenotypic effects.
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- 2016
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- Publication type:
- Other
Natural Yeast Promoter Variants Reveal Epistasis in the Generation of Transcriptional-Mediated Noise and Its Potential Benefit in Stressful Conditions.
- Published in:
- Genome Biology & Evolution, 2015, v. 7, n. 4, p. 969, doi. 10.1093/gbe/evv047
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- Publication type:
- Article
Le rôle des phénomènes aléatoires dans le cancer.
- Published in:
- Médecine Sciences, 2014, v. 30, n. 6/7, p. 693, doi. 10.1051/medsci/20143006023
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- Publication type:
- Article
Stochastic gene expression stabilization as a new therapeutic strategy for cancer.
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- BioEssays, 2012, v. 34, n. 3, p. 170, doi. 10.1002/bies.201100149
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- Publication type:
- Article
Stochastic gene expression is the driving force of cancer.
- Published in:
- BioEssays, 2011, v. 33, n. 10, p. 781, doi. 10.1002/bies.201100092
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- Publication type:
- Article
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway.
- Published in:
- Carcinogenesis, 2010, v. 31, n. 10, p. 1742, doi. 10.1093/carcin/bgq166
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- Publication type:
- Article
Noise-Driven Heterogeneity in the Rate of Genetic-Variant Generation as a Basis for Evolvability.
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- Genetics, 2010, v. 185, n. 2, p. 395, doi. 10.1534/genetics.110.118190
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- Publication type:
- Article
Characterization of a Natural Mutator Variant of Human DNA Polymerase λ which Promotes Chromosomal Instability by Compromising NHEJ.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007290
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- Publication type:
- Article
Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells.
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- Nucleic Acids Research, 2007, v. 35, n. 11, p. 3551, doi. 10.1093/nar/gkm243
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- Publication type:
- Article
The DNA polymerase λ is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 10, p. 2998, doi. 10.1093/nar/gkl380
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- Publication type:
- Article
Elements for an integrated approach to carcinogenesis.
- Published in:
- 2006
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- Publication type:
- Correction notice
Cancer cell undifferentiation: a matter of expression rather than mutations?
- Published in:
- 2006
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- Publication type:
- Letter
Stochastic gene expression, disruption of tissue averaging effects and cancer as a disease of development.
- Published in:
- BioEssays, 2005, v. 27, n. 12, p. 1277, doi. 10.1002/bies.20326
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- Publication type:
- Article
DNA polymerase β overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells.
- Published in:
- Nucleic Acids Research, 2004, v. 32, n. 17, p. 5104, doi. 10.1093/nar/gkh848
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- Publication type:
- Article