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Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.
Published in:
Biochemical Journal, 2020, v. 477, n. 8, p. 1525, doi. 10.1042/BCJ20200128
By:
- Byrne, Matthew J.;
- Nasir, Nazia;
- Basmadjian, Christine;
- Bhatia, Chitra;
- Cunnison, Rory F.;
- Carr, Katherine H.;
- Mas-Droux, Corine;
- Yeoh, Sharon;
- Cano, Céline;
- Bayliss, Richard
Publication type:
Article
Cyclizations and fragmentations in the alkylation of 6‐chloro‐5‐hydroxy‐4‐aminopyrimidines with aminoalkyl chlorides.
Published in:
Journal of Heterocyclic Chemistry, 2021, v. 58, n. 4, p. 947, doi. 10.1002/jhet.4228
By:
- Picazo, Edwige M. H.;
- Heptinstall, Amy B.;
- Wilson, David M.;
- Cano, Céline;
- Golding, Bernard T.;
- Waring, Michael J.
Publication type:
Article
Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification.
Published in:
Clinical Chemistry, 2018, v. 64, n. 2, p. 346, doi. 10.1373/clinchem.2017.275867
By:
- Hill, Simon L.;
- Dunn, Michael;
- Cano, Céline;
- Harnor, Suzannah J.;
- Hardcastle, Ian R.;
- Grundlingh, Johann;
- Dargan, Paul I.;
- Wood, David M.;
- Tucker, Simon;
- Bartram, Thomas;
- Thomas, Simon H. L.
Publication type:
Article
Targeting DNA-Dependent Protein Kinase for Cancer Therapy.
Published in:
ChemMedChem, 2017, v. 12, n. 12, p. 895, doi. 10.1002/cmdc.201700143
By:
- Harnor, Suzannah J.;
- Brennan, Alfie;
- Cano, Céline
Publication type:
Article
Synthesis and Biological Evaluation of N<sup>2</sup>-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors.
Published in:
ChemMedChem, 2016, v. 11, n. 16, p. 1705, doi. 10.1002/cmdc.201600108
By:
- Cortese, Daniela;
- Chegaev, Konstantin;
- Guglielmo, Stefano;
- Wang, Lan Z.;
- Golding, Bernard T.;
- Cano, Céline;
- Fruttero, Roberta
Publication type:
Article

Found: 5

Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine.

Cyclizations and fragmentations in the alkylation of 6‐chloro‐5‐hydroxy‐4‐aminopyrimidines with aminoalkyl chlorides.

Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification.

Targeting DNA-Dependent Protein Kinase for Cancer Therapy.

Synthesis and Biological Evaluation of N<sup>2</sup>-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors.