Works by Canard, Bruno
Results: 65
The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution.
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- PLoS Biology, 2024, v. 22, n. 8, p. 1, doi. 10.1371/journal.pbio.3002743
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- Article
The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity.
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- Frontiers in Microbiology, 2019, p. 1, doi. 10.3389/fmicb.2019.01813
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- Article
An RNA cap (nucleoside‐2′‐O‐)‐methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization.
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- EMBO Journal, 2002, v. 21, n. 11, p. 2757, doi. 10.1093/emboj/21.11.2757
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- Article
An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization.
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- EMBO Journal, 2002, v. 21, n. 11, p. 2757, doi. 10.1093/emboj/21.11.2757
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- Article
Structural basis for activation of a-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
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- EMBO Journal, 2000, v. 19, n. 14, p. 3520, doi. 10.1093/emboj/19.14.3520
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- Article
ACTIVATION OF ANTI-REVERSE TRANSCRIPTASE NUCLEOTIDE ANALOGS BY NUCLEOSIDE DIPHOSPHATE KINASE: IMPROVEMENT BY α-BORANOPHOSPHATE SUBSTITUTION.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 297, doi. 10.1081/NCN-100002300
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Observation of arenavirus nucleoprotein heptamer assembly.
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- FEBS Open Bio, 2021, v. 11, n. 4, p. 1076, doi. 10.1002/2211-5463.13106
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- Article
Evaluation of Adamantane Derivatives as Inhibitors of Dengue Virus mRNA Cap Methyltransferase by Docking and Molecular Dynamics Simulations.
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- Molecular Informatics, 2013, v. 32, n. 2, p. 155, doi. 10.1002/minf.201200107
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- Article
Phytochemical Study of Myrtopsis corymbosa, Perspectives for Anti-dengue Natural Compound Research.
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- Records of Natural Products, 2013, v. 7, n. 3, p. 250
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- Article
The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
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- PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004733
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- Article
Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome.
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- PLoS Pathogens, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.ppat.1002912
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- Article
The Hexamer Structure of the Rift Valley Fever Virus Nucleoprotein Suggests a Mechanism for its Assembly into Ribonucleoprotein Complexes.
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- PLoS Pathogens, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.ppat.1002030
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- Article
Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2'-O-Methyltransferase nsp10/nsp16 Complex.
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- PLoS Pathogens, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.ppat.1002059
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- Article
In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation.
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- PLoS Pathogens, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.ppat.1000863
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- Article
Dengue virus 3 NS5 methyltransferase domain: expression, purification, crystallization and first structural data from microcrystalline specimens.
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- Zeitschrift für Kristallographie. Crystalline Materials, 2018, v. 233, n. 5, p. 309, doi. 10.1515/zkri-2017-2091
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- Article
Viral Instant Mutation Viewer: A Tool to Speed Up the Identification and Analysis of New SARS-CoV-2 Emerging Variants and Beyond.
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- Viruses (1999-4915), 2023, v. 15, n. 8, p. 1628, doi. 10.3390/v15081628
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- Article
Amino Acid Polymorphisms on the Brazilian Strain of Yellow Fever Virus Methyltransferase Are Related to the Host's Immune Evasion Mediated by Type I Interferon.
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- Viruses (1999-4915), 2023, v. 15, n. 1, p. 191, doi. 10.3390/v15010191
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- Article
La protéine L du virus Ébola porte une nouvelle activité enzymatique impliquée dans la méthylation interne des ARN.
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- Médecine Sciences, 2018, v. 34, n. 11, p. 919, doi. 10.1051/medsci/2018230
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- Article
Stratégies de formation de la structure coiffe chez les virus à ARN.
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- Médecine Sciences, 2012, v. 28, n. 4, p. 423, doi. 10.1051/medsci/2012284021
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- Article
A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus.
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- EMBO Journal, 2006, v. 25, n. 20, p. 4933, doi. 10.1038/sj.emboj.7601368
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- Article
X-ray structure and activities of an essential Mononegavirales L-protein domain.
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- Nature Communications, 2015, v. 6, n. 11, p. 8749, doi. 10.1038/ncomms9749
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- Article
Primer-Dependent and Primer-Independent Initiation of Double Stranded RNA Synthesis by Purified Arabidopsis RNA-Dependent RNA Polymerases RDR2 and RDR6.
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- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120100
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- Article
<sup>1</sup>H, <sup>13</sup>C, <sup>15</sup>N backbone resonance assignment of apo and ADP-ribose bound forms of the macro domain of Hepatitis E virus through solution NMR spectroscopy.
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- Biomolecular NMR Assignments, 2023, v. 17, n. 1, p. 1, doi. 10.1007/s12104-022-10111-5
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- Article
Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein.
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- Viruses (1999-4915), 2020, v. 12, n. 7, p. 772, doi. 10.3390/v12070772
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- Article
Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases.
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- Viruses (1999-4915), 2018, v. 10, n. 2, p. 59, doi. 10.3390/v10020059
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- Article
Comparative Production Analysis of Three Phlebovirus Nucleoproteins under Denaturing or Non-Denaturing Conditions for Crystallographic Studies.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 1, p. 1, doi. 10.1371/journal.pntd.0000936
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Comparative Production Analysis of Three Phlebovirus Nucleoproteins under Denaturing or Non-Denaturing Conditions for Crystallographic Studies.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 1, p. 1, doi. 10.1371/journal.pntd.0000936
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- Article
Drugs against SARS‐CoV‐2: What do we know about their mode of action?
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- Reviews in Medical Virology, 2020, v. 30, n. 6, p. 1, doi. 10.1002/rmv.2143
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- Article
The non-structural protein Nsp10 of mouse hepatitis virus binds zinc ions and nucleic acids
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- FEBS Letters, 2006, v. 580, n. 17, p. 4143, doi. 10.1016/j.febslet.2006.06.061
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- Article
MeDor: a metaserver for predicting protein disorder.
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- BMC Genomics, 2008, v. 9, p. 1, doi. 10.1186/1471-2164-9-S2-S25
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- Article
Conventional and unconventional mechanisms for capping viral mRNA.
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- Nature Reviews Microbiology, 2012, v. 10, n. 1, p. 51, doi. 10.1038/nrmicro2675
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- Article
Virologic and Enzymatic Studies Revealing the Mechanism of K65R- and Q151M-Associated HIV-1 Drug Resistance Towards Emtricitabine and Lamivudine.
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- Nucleosides, Nucleotides & Nucleic Acids, 2006, v. 25, n. 1, p. 89, doi. 10.1080/15257770500379157
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- Article
Borano-Nucleotides: New Analogues to Circumvent HIV-1 RT-Mediated Nucleoside Drug-Resistance.
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- Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 419, doi. 10.1081/NCN-200059951
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- Article
Structural flexibility of Toscana virus nucleoprotein in the presence of a single‐chain camelid antibody.
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- Acta Crystallographica: Section D, Structural Biology, 2024, v. 80, n. 2, p. 113, doi. 10.1107/S2059798324000196
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- Article
Structure and oligomerization state of the C‐terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein.
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- Acta Crystallographica: Section D, Structural Biology, 2019, v. 75, n. 1, p. 8, doi. 10.1107/S2059798318014948
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- Article
Toscana virus nucleoprotein oligomer organization observed in solution.
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- Acta Crystallographica: Section D, Structural Biology, 2017, v. 73, n. 8, p. 650, doi. 10.1107/S2059798317008774
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- Article
Activity inhibition and crystal polymorphism induced by active-site metal swapping.
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- Acta Crystallographica: Section D, Structural Biology, 2017, v. 73, n. 8, p. 641, doi. 10.1107/S205979831700866X
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- Article
Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering.
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- Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 2, p. 192, doi. 10.1107/S2059798315024328
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- Article
Design, Synthesis and Discovery of N,N'‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication.
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- ChemMedChem, 2020, v. 15, n. 4, p. 385, doi. 10.1002/cmdc.201900533
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Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2437, doi. 10.3390/ijms25042437
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A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 8, p. 1021, doi. 10.3390/ph15081021
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The WHO mission report struggles to trace the origins of the SARS-CoV-2 epidemic.
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- Virologie, 2021, v. 25, n. 3, p. 42, doi. 10.1684/vir.2021.0902
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Le rapport de la mission OMS peine à retracer les origines de l'épidémie de SARS-CoV-2.
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- Virologie, 2021, v. 25, n. 3, p. 148, doi. 10.1684/vir.2021.0901
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Structure and biochemical analysis of Kokobera virus helicase.
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- Proteins, 2008, v. 70, n. 3, p. 1120, doi. 10.1002/prot.21812
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A practical overview of protein disorder prediction methods.
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- Proteins, 2006, v. 65, n. 1, p. 1, doi. 10.1002/prot.21075
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Assessing protein disorder and induced folding.
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- Proteins, 2006, v. 62, n. 1, p. 24, doi. 10.1002/prot.20750
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Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.70968
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An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.
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- Nucleic Acids Research, 2024, v. 52, n. 3, p. 1325, doi. 10.1093/nar/gkad1194
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- Article
Internal RNA 2′-O-methylation on the HIV-1 genome impairs reverse transcription.
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- Nucleic Acids Research, 2024, v. 52, n. 3, p. 1359, doi. 10.1093/nar/gkad1134
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- Article
Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect.
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- Nucleic Acids Research, 2023, v. 51, n. 6, p. 2501, doi. 10.1093/nar/gkac996
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- Article