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Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence.
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- Aging Cell, 2024, v. 23, n. 3, p. 1, doi. 10.1111/acel.14060
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- Article
Proteomic Analysis of the Senescence-Associated Secretory Phenotype: GDF-15, IGFBP-2, and Cystatin-C Are Associated With Multiple Aging Traits.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 3, p. 1, doi. 10.1093/gerona/glad265
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- Article
Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy.
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- Aging Cell, 2024, v. 23, n. 1, p. 1, doi. 10.1111/acel.13921
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- Article
Additional Cover.
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- Aging Cell, 2024, v. 23, n. 1, p. 1, doi. 10.1111/acel.14085
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- Article
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury.
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- EMBO Molecular Medicine, 2023, v. 15, n. 12, p. 1, doi. 10.15252/emmm.202317907
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- Article
Chromosome instability and aneuploidy in the mammalian brain.
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- Chromosome Research, 2023, v. 31, n. 4, p. 1, doi. 10.1007/s10577-023-09740-w
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- Article
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
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- GeroScience, 2023, v. 45, n. 5, p. 2983, doi. 10.1007/s11357-023-00870-x
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- Article
Accelerated replicative senescence of ataxia‐telangiectasia skin fibroblasts is retained at physiologic oxygen levels, with unique and common transcriptional patterns.
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- Aging Cell, 2023, v. 22, n. 8, p. 1, doi. 10.1111/acel.13869
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- Article
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain.
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- Aging Cell, 2023, v. 22, n. 7, p. 1, doi. 10.1111/acel.13832
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- Article
A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence.
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- G3: Genes | Genomes | Genetics, 2023, v. 13, n. 7, p. 1, doi. 10.1093/g3journal/jkad091
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- Article
Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35487-9
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- Article
Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal.
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- Aging Cell, 2023, v. 22, n. 1, p. 1, doi. 10.1111/acel.13750
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- Article
Fisetin Supplementation Improves Age‐Related Vascular Endothelial Function by Suppressing Cellular Senescence and Mitochondrial Oxidative Stress.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R1931
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- Article
Cellular Senescence and the Associated Secretome Contribute to Age‐Related Vascular Dysfunction.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2053
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- Article
Extending human healthspan and longevity: a symposium report.
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- Annals of the New York Academy of Sciences, 2022, v. 1507, n. 1, p. 70, doi. 10.1111/nyas.14681
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- Article
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.
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- 2021
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- journal article
Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions.
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- Aging Cell, 2021, v. 20, n. 6, p. 1, doi. 10.1111/acel.13357
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- Article
Apigenin restores endothelial function by ameliorating oxidative stress, prevents foam cell formation, reverses aortic stiffening, and mitigates vascular inflammation with aging.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02221
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- Article
Cellular senescence mediates doxorubicin‐induced arterial dysfunction via activation of mitochondrial oxidative stress and the mammalian target of rapamycin.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.00283
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- Article
Late‐Life Treatment with the Senolytic ABT‐263 Reverses Aortic Stiffening and Improves Endothelial Function with Aging.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02642
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- Article
Age‐associated expression of p21and p53 during human wound healing.
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- Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13354
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Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.
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- 2021
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- journal article
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16<sup>INK4a</sup> increase.
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- Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13226
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- Article
Non‐canonical ATM/MRN activities temporally define the senescence secretory program.
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- EMBO Reports, 2020, v. 21, n. 10, p. 1, doi. 10.15252/embr.202050718
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- Article
IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis.
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- 2020
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- journal article
Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71042-6
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- Article
Role of immune cells in the removal of deleterious senescent cells.
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- Immunity & Ageing, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12979-020-00187-9
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- Article
Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15838-0
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- Article
Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation–induced impairment of neurovascular coupling responses protecting cognitive function in mice.
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- GeroScience, 2020, v. 42, n. 2, p. 409, doi. 10.1007/s11357-020-00154-8
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- Article
Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity.
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- Aging Cell, 2020, v. 19, n. 3, p. 1, doi. 10.1111/acel.13117
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- Article
Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.
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- Aging Cell, 2020, v. 19, n. 3, p. 1, doi. 10.1111/acel.13072
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- Article
A proteomic atlas of senescence-associated secretomes for aging biomarker development.
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- PLoS Biology, 2020, v. 18, n. 1, p. 1, doi. 10.1371/journal.pbio.3000599
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- Article
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
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- PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0227887
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- Article
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression.
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- Aging Cell, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/acel.13027
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Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors.
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- 2019
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- Publication type:
- journal article
A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46606-w
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- Article
Senescent cells evade immune clearance via HLA-E-mediated NK and CD8<sup>+</sup> T cell inhibition.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10335-5
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- Article
Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice.
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- Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12923
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- Article
Systemic clearance of p16<sup>INK4a</sup>‐positive senescent cells mitigates age‐associated intervertebral disc degeneration.
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- Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12927
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- Article
Oxidation resistance 1 is a novel senolytic target.
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- Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12780
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- Article
Senescent cells and osteoarthritis: a painful connection.
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- 2018
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- journal article
Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence.
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- Aging Cell, 2017, v. 16, n. 5, p. 1043, doi. 10.1111/acel.12632
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Disease drivers of aging.
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- Annals of the New York Academy of Sciences, 2016, v. 1386, n. 1, p. 45, doi. 10.1111/nyas.13299
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- Article
Cellular Senescence and Lung Function during Aging. Yin and Yang.
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- 2016
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- journal article
Whole Chromosome Instability induces senescence and promotes SASP.
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- Scientific Reports, 2016, p. 35218, doi. 10.1038/srep35218
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- Article
Aging of the immune system: Focus on inflammation and vaccination.
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- European Journal of Immunology, 2016, v. 46, n. 10, p. 2286, doi. 10.1002/eji.201546178
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Context-dependent effects of cellular senescence in cancer development.
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- 2016
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- journal article
Simvastatin suppresses breast cancer cell proliferation induced by senescent cells.
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- Scientific Reports, 2015, p. 17895, doi. 10.1038/srep17895
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- Article
Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin.
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- Journal of Investigative Dermatology, 2015, v. 135, n. 7, p. 1722, doi. 10.1038/jid.2015.108
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- Article
Montagna Symposium 2014-Skin Aging: Molecular Mechanisms and Tissue Consequences.
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- Journal of Investigative Dermatology, 2015, v. 135, n. 4, p. 950, doi. 10.1038/jid.2014.546
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- Article