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Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages.
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- PLoS Neglected Tropical Diseases, 2024, v. 18, n. 2, p. 1, doi. 10.1371/journal.pntd.0011992
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- Article
Synthetic derivatives of natural cinnamic acids as potential anti‐colorectal cancer agents.
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- Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14415
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- Article
Pioneering first‐in‐class FAAH‐HDAC inhibitors as potential multitarget neuroprotective agents.
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- Archiv der Pharmazie, 2023, v. 356, n. 12, p. 1, doi. 10.1002/ardp.202300410
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- Article
Development of 1‐(2‐aminophenyl)pyrrole‐based amides acting as human topoisomerase I inhibitors.
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- Archiv der Pharmazie, 2023, v. 356, n. 10, p. 1, doi. 10.1002/ardp.202300270
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- Article
Development of Quinazolinone Derivatives as Modulators of Virulence Factors of Pseudomonas aeruginosa Cystic Fibrosis Strains.
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- Molecules, 2023, v. 28, n. 18, p. 6535, doi. 10.3390/molecules28186535
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- Article
Expression, Purification, Structural and Functional Characterization of Recombinant Human Parvulin 17.
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- Molecular Biotechnology, 2023, v. 65, n. 3, p. 337, doi. 10.1007/s12033-022-00493-1
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- Article
Synthesis of Unsymmetrical Squaramides as Allosteric GSK‐3β Inhibitors Promoting β‐Catenin‐Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells.
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- ChemMedChem, 2022, v. 17, n. 24, p. 1, doi. 10.1002/cmdc.202200456
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Front Cover: Synthesis of Unsymmetrical Squaramides as Allosteric GSK‐3β Inhibitors Promoting β‐Catenin‐Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells (ChemMedChem 24/2022).
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- ChemMedChem, 2022, v. 17, n. 24, p. 1, doi. 10.1002/cmdc.202200663
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- Article
A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 10014, doi. 10.3390/ijms231710014
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- Article
Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits Ca V 1.2 and Stimulates K Ca 1.1 Channels.
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- Marine Drugs, 2022, v. 20, n. 8, p. 515, doi. 10.3390/md20080515
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- Article
Design and Synthesis of Oligopeptidic Parvulin Inhibitors.
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- ChemMedChem, 2022, v. 17, n. 11, p. 1, doi. 10.1002/cmdc.202200050
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- Article
Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a New Protocol for Investigating the Mechanisms of Idiopathic Pulmonary Fibrosis.
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- Cells (2073-4409), 2022, v. 11, n. 9, p. N.PAG, doi. 10.3390/cells11091441
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- Article
In Silico Analysis of Peptide-Based Derivatives Containing Bifunctional Warheads Engaging Prime and Non-Prime Subsites to Covalent Binding SARS-CoV-2 Main Protease (M pro).
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- Computation, 2022, v. 10, n. 5, p. 69, doi. 10.3390/computation10050069
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- Article
Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases.
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- Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082561
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- Article
Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals.
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- Antioxidants, 2022, v. 11, n. 3, p. 437, doi. 10.3390/antiox11030437
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Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition.
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- Cells (2073-4409), 2022, v. 11, n. 3, p. 471, doi. 10.3390/cells11030471
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- Article
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity.
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- Molecules, 2022, v. 27, n. 2, p. 463, doi. 10.3390/molecules27020463
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- Article
A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93408-0
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- Article
Cinnamides Target Leishmania amazonensis Arginase Selectively.
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- Molecules, 2020, v. 25, n. 22, p. 5271, doi. 10.3390/molecules25225271
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- Article
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas.
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- Medicinal Research Reviews, 2020, v. 40, n. 3, p. 1002, doi. 10.1002/med.21646
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- Article
Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors.
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- Molecules, 2020, v. 25, n. 8, p. 1952, doi. 10.3390/molecules25081952
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- Article
A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles.
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- Molecules, 2019, v. 24, n. 23, p. 4373, doi. 10.3390/molecules24234373
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- Article
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase.
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- Chemical Biology & Drug Design, 2019, v. 93, n. 2, p. 139, doi. 10.1111/cbdd.13391
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- Article
Author Correction: The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-37392-y
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- Article
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain.
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- ChemMedChem, 2018, v. 13, n. 19, p. 2090, doi. 10.1002/cmdc.201800397
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- Article
Development of Potent Inhibitors of the <italic>Mycobacterium tuberculosis</italic> Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages.
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- ChemMedChem, 2018, v. 13, n. 5, p. 422, doi. 10.1002/cmdc.201700759
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- Article
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2074, doi. 10.1002/cmdc.201700551
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- Article
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity.
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- Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-11606-1
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- Article
Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.
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- Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00451
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- Article
Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells.
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- Investigational New Drugs, 2016, v. 34, n. 5, p. 663, doi. 10.1007/s10637-016-0366-3
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- Article
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL-induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells.
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- International Journal of Oncology, 2016, v. 49, n. 1, p. 74, doi. 10.3892/ijo.2016.3518
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- Article
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15.
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- Investigational New Drugs, 2016, v. 34, n. 2, p. 159, doi. 10.1007/s10637-016-0331-1
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- Article
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors.
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- Chemical Biology & Drug Design, 2016, v. 87, n. 1, p. 112, doi. 10.1111/cbdd.12630
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- Article
Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines.
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- Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3748, doi. 10.3892/mmr.2015.3832
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- Article
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking.
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- Scientific Reports, 2015, p. 9705, doi. 10.1038/srep09705
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- Article
Disease-Modifying Anti-Alzheimer's Drugs: Inhibitors of Human Cholinesterases Interfering with β-Amyloid Aggregation.
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- CNS Neuroscience & Therapeutics, 2014, v. 20, n. 7, p. 624, doi. 10.1111/cns.12290
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- Article
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.
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- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 585, doi. 10.1007/s00280-009-1200-9
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- Article
Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines.
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- Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 289, doi. 10.1007/s00280-009-1033-6
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- Article
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin.
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- Journal of Molecular Medicine, 2008, v. 86, n. 4, p. 457, doi. 10.1007/s00109-008-0312-8
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- Article
Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fosmRNA) levels.
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- Archives of Toxicology, 2005, v. 79, n. 3, p. 129, doi. 10.1007/s00204-004-0617-5
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- Article
Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6
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- FEBS Letters, 2002, v. 515, n. 1-3, p. 66, doi. 10.1016/S0014-5793(02)02440-7
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- Article