Found: 26
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Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 11, p. 2555, doi. 10.1007/s11095-023-03554-5
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- Publication type:
- Article
Pharmacokinetic basis for dosing high‐dose methotrexate in infants and young children with malignant brain tumours.
- Published in:
- British Journal of Clinical Pharmacology, 2020, v. 86, n. 2, p. 362, doi. 10.1111/bcp.14160
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- Publication type:
- Article
The impact of tacrolimus exposure on extrarenal adverse effects in adult renal transplant recipients.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 3, p. 516, doi. 10.1111/bcp.13811
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- Publication type:
- Article
Development and Validation of a Sensitive and Specific LC-MS/MS Method for IWR-1-Endo, a Wnt Signaling Inhibitor: Application to a Cerebral Microdialysis Study.
- Published in:
- Molecules, 2022, v. 27, n. 17, p. 5448, doi. 10.3390/molecules27175448
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- Publication type:
- Article
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
- Published in:
- Neuro-Oncology, 2021, v. 23, n. 10, p. 1777, doi. 10.1093/neuonc/noab047
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- Publication type:
- Article
Developing Therapy for Every Kid With Cancer – Summary of a Scientific Session at the 2023 ASCPT Meeting.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 2, p. 185, doi. 10.1002/cpt.3101
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- Publication type:
- Article
Model‐Informed Approaches and Innovative Clinical Trial Design for Adeno‐Associated Viral Vector‐Based Gene Therapy Product Development: A White Paper.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 515, doi. 10.1002/cpt.2972
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- Publication type:
- Article
CNS Penetration of Cyclophosphamide and Metabolites in Mice Bearing Group 3 Medulloblastoma and Non-Tumor Bearing Mice.
- Published in:
- Journal of Pharmacy & Pharmaceutical Sciences, 2019, v. 22, p. 612
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- Publication type:
- Article
An LC/ESI–MS/MS method to quantify the PI3K inhibitor GDC‐0084 in human plasma and cerebrospinal fluid: Validation and clinical application.
- Published in:
- Biomedical Chromatography, 2020, v. 34, n. 1, p. N.PAG, doi. 10.1002/bmc.4697
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- Publication type:
- Article
Population pharmacokinetics of crenolanib in children and young adults with brain tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 4, p. 459, doi. 10.1007/s00280-022-04412-8
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- Publication type:
- Article
Population pharmacokinetic analysis of crizotinib in children with progressive/recurrent high-grade and diffuse intrinsic pontine gliomas.
- Published in:
- 2021
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- Publication type:
- journal article
Correction to: Pharmacokinetics and safety of erlotinib and its metabolite OSI-420 in infants and children with primary brain tumors.
- Published in:
- 2020
- By:
- Publication type:
- corrected article
Pharmacokinetics and safety of erlotinib and its metabolite OSI-420 in infants and children with primary brain tumors.
- Published in:
- 2019
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- Publication type:
- journal article
CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors.
- Published in:
- 2019
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- Publication type:
- journal article
Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report.
- Published in:
- Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac055
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- Publication type:
- Article
Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 599, doi. 10.1002/psp4.12627
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- Publication type:
- Article
Topotecan clearance based on a single sample and a population pharmacokinetic model: Application to a pediatric high‐risk neuroblastoma clinical trial.
- Published in:
- Pediatric Blood & Cancer, 2023, v. 70, n. 11, p. 1, doi. 10.1002/pbc.30658
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- Publication type:
- Article
A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC‐042).
- Published in:
- Pediatric Blood & Cancer, 2021, v. 68, n. 4, p. 1, doi. 10.1002/pbc.28879
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- Publication type:
- Article
Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib.
- Published in:
- Clinical Pharmacokinetics, 2021, v. 60, n. 3, p. 283, doi. 10.1007/s40262-020-00967-y
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- Publication type:
- Article
Population Pharmacokinetics of Tacrolimus in Transplant Recipients: What Did We Learn About Sources of Interindividual Variabilities?
- Published in:
- Journal of Clinical Pharmacology, 2019, v. 59, n. 3, p. 309, doi. 10.1002/jcph.1325
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- Publication type:
- Article
Tacrolimus Population Pharmacokinetics and Multiple CYP3A5 Genotypes in Black and White Renal Transplant Recipients.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 9, p. 1184, doi. 10.1002/jcph.1118
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- Publication type:
- Article
Advancing clinical development for neuronopathic Hunter syndrome through a quantitatively‐driven reverse translation framework.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 4, p. 1, doi. 10.1111/cts.13776
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- Publication type:
- Article
Pharmacokinetically guided dosing of oral sorafenib in pediatric hepatocellular carcinoma: A simulation study.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 6, p. 2152, doi. 10.1111/cts.13069
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- Publication type:
- Article
Evaluation of the performance of a prior tacrolimus population pharmacokinetic kidney transplant model among adult allogeneic hematopoietic stem cell transplant patients.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 3, p. 908, doi. 10.1111/cts.12956
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- Publication type:
- Article
Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor.
- Published in:
- Neuro-Oncology, 2023, v. 25, n. 2, p. 386, doi. 10.1093/neuonc/noac151
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- Publication type:
- Article
A phase 1 trial of everolimus and bevacizumab in children with recurrent solid tumors.
- Published in:
- 2020
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- Publication type:
- journal article