Works by Calixto, J B

Results: 18

Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells.

Published in:

2011

By:

Dutra, RC;
Cola, M;
Leite, DFP;
Bento, AF;
Claudino, RF;
Nascimento, AFZ;
Leal, PC;
Calixto, JB;
Dutra, R C;
Leite, D F P;
Bento, A F;
Claudino, R F;
Nascimento, A F Z;
Leal, P C;
Calixto, J B

Publication type:

journal article

Effects of indomethacin-loaded nanocapsules in experimental models of inflammation in rats.

Published in:

2009

By:

Bernardi, A;
Zilberstein, ACCV;
Jäger, E;
Campos, MM;
Morrone, FB;
Calixto, JB;
Pohlmann, AR;
Guterres, SS;
Battastini, AMO;
Zilberstein, A C C V;
Jäger, E;
Campos, M M;
Morrone, F B;
Calixto, J B;
Pohlmann, A R;
Guterres, S S;
Battastini, A M O

Publication type:

journal article

Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis.

Published in:

2009

By:

Vitor, CE;
Figueiredo, CP;
Hara, DB;
Bento, AF;
Mazzuco, TL;
Calixto, JB;
Vitor, C E;
Figueiredo, C P;
Hara, D B;
Bento, A F;
Mazzuco, T L;
Calixto, J B

Publication type:

journal article

The relevance of kinin B1 receptor upregulation in a mouse model of colitis.

Published in:

2008

By:

Hara, D. B.;
Leite, D. F. P.;
Fernandes, E. S.;
Passos, G. F.;
Guimarães, A. O.;
Pesquero, J. B.;
Campos, M. M.;
Calixto, J. B.;
Guimarães, A O

Publication type:

journal article

Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.

Published in:

2008

By:

Costa, R.;
Marotta, D. M.;
Manjavachi, M. N.;
Fernandes, E. S.;
Lima-Garcia, J. F.;
Paszcuk, A. F.;
Quintão, N. L. M.;
Juliano, L.;
Brain, S. D.;
Calixto, J. B.;
Quintão, N L M

Publication type:

journal article

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.

Published in:

British Journal of Pharmacology, 2007, v. 151, n. 5, p. 618, doi. 10.1038/sj.bjp.0707270

By:

Medeiros, R.;
Passos, G. F.;
Vitor, C. E.;
Koepp, J.;
Mazzuco, T. L.;
Pianowski, L. F.;
Campos, M. M.;
Calixto, J. B.

Publication type:

Article

Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 6, p. 727, doi. 10.1038/sj.bjp.0707149

By:

Kassuya, C. A. L.;
Ferreira, J.;
Claudino, R. F.;
Calixto, J. B.

Publication type:

Article

Bradykinin down-regulates LPS-induced eosinophil accumulation in the pleural cavity of mice through type 2-kinin receptor activation: a role for prostaglandins.

Published in:

1999

By:

Silva, A R;
Larangeira, A P;
Pacheco, P;
Calixto, J B;
Henriques, M G M O;
Bozza, P T;
Castro-Faria-Neto, H C;
Henriques, M G

Publication type:

journal article

Non-clinical studies in the process of new drug development – Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies.

Published in:

Brazilian Journal of Medical & Biological Research, 2016, v. 49, n. 12, p. 1, doi. 10.1590/1414-431X20165646

By:

Andrade, E. L.;
Bento, A. F.;
Cavalli, J.;
Oliveira, S. K.;
Schwanke, R. C.;
Siqueira, J. M.;
Freitas, C. S.;
Marcon, R.;
Calixto, J. B.

Publication type:

Article

Non-clinical studies required for new drug development – Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies.

Published in:

Brazilian Journal of Medical & Biological Research, 2016, v. 49, n. 11, p. 1, doi. 10.1590/1414-431X20165644

By:

Andrade, E. L.;
Bento, A. F.;
Cavalli, J.;
Oliveira, S. K.;
Freitas, C. S.;
Marcon, R.;
Schwanke, R. C.;
Siqueira, J. M.;
Calixto, J. B.

Publication type:

Article

Exacerbation of DSS-induced colitis in mice lacking kinin B(1) receptors through compensatory up-regulation of kinin B(2) receptors: the role of tight junctions and intestinal homeostasis.

Published in:

2013

By:

Marcon R;
Claudino R;
Dutra R;
Bento A;
Schmidt E;
Bouzon Z;
Sordi R;
Morais R;
Pesquero J;
Calixto J;
Marcon, R;
Claudino, R F;
Dutra, R C;
Bento, A F;
Schmidt, E C;
Bouzon, Z L;
Sordi, R;
Morais, R L T;
Pesquero, J B;
Calixto, J B

Publication type:

journal article

Inflammatory muscle pain is dependent on the activation of kinin B₁ and B₂ receptors and intracellular kinase pathways.

Published in:

2012

By:

Meotti FC;
Campos R;
da Silva K;
Paszcuk AF;
Costa R;
Calixto JB;
Meotti, F C;
Campos, R;
da Silva, Kabs;
Paszcuk, A F;
Costa, R;
Calixto, J B

Publication type:

journal article

The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats.

Published in:

2011

By:

Lima-Garcia, JF;
Dutra, RC;
da Silva, KABS;
Motta, EM;
Campos, MM;
Calixto, JB;
Lima-Garcia, J F;
Dutra, R C;
Motta, E M;
Campos, M M;
Calixto, J B

Publication type:

journal article

Central involvement of kinin B1 and B2 receptors in the febrile response induced by endotoxin in rats.

Published in:

British Journal of Pharmacology, 1997, v. 121, n. 2, p. 296, doi. 10.1038/sj.bjp.0701110

By:

Coelho, M M;
Oliveira, C R;
Pajolla, G P;
Calixto, J B;
Pelá, I R

Publication type:

Article

Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil.

Published in:

2001

By:

Veiga, Valdir F.;
Zunino, Luciano;
Calixto, João B.;
Patitucci, Maria L.;
Pinto, Ângelo C.;
Veiga, V F Jr;
Zunino, L;
Calixto, J B;
Patitucci, M L;
Pinto, A C

Publication type:

journal article

Naturally occurring antinociceptive substances from plants.

Published in:

2000

By:

Calixto, João B.;
Beirith, Alessandra;
Ferreira, Juliano;
Santos, Adair R. S.;
Filho, Valdir Cechinel;
Yunes, Rosendo A.;
Calixto, J B;
Beirith, A;
Ferreira, J;
Santos, A R;
Filho, V C;
Yunes, R A

Publication type:

journal article

Vascular action of the crude hydroalcoholic extract from Hymenaea martiana on the isolated rat and rabbit aorta.

Published in:

Phytotherapy Research, 1992, v. 6, n. 6, p. 327, doi. 10.1002/ptr.2650060610

By:

Calixto, J. B.;
Yunes, R. A.;
Medeiros, Y. S.

Publication type:

Article

Differential antagonistic effect of hydroalcoholic extract from Hymenaea martiana hayne arzeik on kinin and other agonist-induced contractions of the isolated rat uterus and Guinea-pig ileum.

Published in:

Phytotherapy Research, 1992, v. 6, n. 6, p. 322, doi. 10.1002/ptr.2650060609

By:

Calixto, J. B.;
Yunes, R. A.;
Medeiros, Y. S.

Publication type:

Article

Works by Calixto, J B

Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells.

Effects of indomethacin-loaded nanocapsules in experimental models of inflammation in rats.

Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis.

The relevance of kinin B1 receptor upregulation in a mouse model of colitis.

Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.

Intraplantar PGE<sub>2</sub> causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases.

Bradykinin down-regulates LPS-induced eosinophil accumulation in the pleural cavity of mice through type 2-kinin receptor activation: a role for prostaglandins.

Non-clinical studies in the process of new drug development – Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies.

Non-clinical studies required for new drug development – Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies.

Exacerbation of DSS-induced colitis in mice lacking kinin B(1) receptors through compensatory up-regulation of kinin B(2) receptors: the role of tight junctions and intestinal homeostasis.

Inflammatory muscle pain is dependent on the activation of kinin B₁ and B₂ receptors and intracellular kinase pathways.

The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats.

Central involvement of kinin B<sub>1</sub> and B<sub>2</sub> receptors in the febrile response induced by endotoxin in rats.

Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil.

Naturally occurring antinociceptive substances from plants.

Vascular action of the crude hydroalcoholic extract from Hymenaea martiana on the isolated rat and rabbit aorta.

Differential antagonistic effect of hydroalcoholic extract from Hymenaea martiana hayne arzeik on kinin and other agonist-induced contractions of the isolated rat uterus and Guinea-pig ileum.