Works by Calingasan, Noel Y.

Results: 40

Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 2, p. 241, doi. 10.1007/s00401-022-02451-2

By:

Parameswaran, Janani;
Goicoechea, Leire;
Planas-Serra, Laura;
Pastor, Antoni;
Ruiz, Montserrat;
Calingasan, Noel Y.;
Guilera, Cristina;
Aso, Ester;
Boada, Jordi;
Pamplona, Reinald;
Portero-Otín, Manuel;
de la Torre, Rafael;
Ferrer, Isidre;
Casasnovas, Carlos;
Pujol, Aurora;
Fourcade, Stéphane

Publication type:

Article

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2467, doi. 10.1523/JNEUROSCI.5253-05.2006

By:

Kiaei, Mahmoud;
Petri, Susanne;
Kipiani, Khatuna;
Gardian, Gabrielle;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Schafer, Peter;
Muller, George W.;
Stewart, Charles;
Hensley, Kenneth;
Beal, M. Flint

Publication type:

Article

Manganese porphyrin given at symptom onset markedly extends survival of ALS mice.

Published in:

Annals of Neurology, 2005, v. 58, n. 2, p. 258

By:

John P. Crow;
Noel Y. Calingasan;
Junyu Chen;
Julie Lynch Hill;
M. Flint Beal

Publication type:

Article

Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease.

Published in:

FASEB Journal, 2009, v. 23, n. 8, p. 2459, doi. 10.1096/fj.09-132928

By:

Dumont, Magali;
Willie, Elizabeth;
Stack, Cliona;
Calingasan, Noel Y.;
Beal, M. Flint;
Lin, Michael T.

Publication type:

Article

Disturbances of the Blood-Brain Barrier without Expression of Amyloid Precursor Protein- Containing Neuritic Clusters or Neuronal Loss during Late Stages of Thiamine Deficiency in Guinea Pigs.

Published in:

Developmental Neuroscience, 1998, v. 20, n. 4/5, p. 454, doi. 10.1159/000017343

By:

Calingasan, Noel Y.;
Park, Larry C.H.;
Gandy, Samuel E.;
Gibson, Gary E.

Publication type:

Article

Alterations of striatal neurons in benign hereditary chorea.

Published in:

Movement Disorders, 2005, v. 20, n. 10, p. 1353, doi. 10.1002/mds.20577

By:

Kleiner-Fisman, Galit;
Calingasan, Noel Y.;
Putt, Mary;
Chen, June;
Beal, M.Flint;
Lang, Anthony E.

Publication type:

Article

Distribution of the α-ketoglutarate dehydrogenase complex in rat brain.

Published in:

Journal of Comparative Neurology, 1994, v. 346, n. 3, p. 461, doi. 10.1002/cne.903460309

By:

Calingasan, Noel Y.;
Baker, Harriet;
Sheu, Kwan-Fu Rex;
Gibson, Gary E.

Publication type:

Article

Celastrol Blocks Neuronal Cell Death and Extends Life in Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Neurodegenerative Diseases, 2005, v. 2, n. 5, p. 246, doi. 10.1159/000090364

By:

Kiaei, Mahmoud;
Kipiani, Khatuna;
Petri, Susanne;
Junyu Chen;
Calingasan, Noel Y.;
Beal, M. Flint

Publication type:

Article

Vascular Endothelium Is a Site of Free Radical Production and Inflammation in Areas of Neuronal Loss in Thiamine-deficient Brain.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 903, n. 1, p. 353, doi. 10.1111/j.1749-6632.2000.tb06386.x

By:

CALINGASAN, NOEL Y.;
GIBSON, GARY E.

Publication type:

Article

Oxidative Stress and a Key Metabolic Enzyme in Alzheimer Brains, Cultured Cells, and an Animal Model of Chronic Oxidative Deficits.

Published in:

Annals of the New York Academy of Sciences, 1999, v. 893, n. 1, p. 79, doi. 10.1111/j.1749-6632.1999.tb07819.x

By:

GIBSON, GARY E.;
PARK, LARRY C. H.;
ZHANG, HUI;
SORBI, SANDRO;
CALINGASAN, NOEL Y.

Publication type:

Article

Expression of glycoprotein VI in vascular endothelial cells.

Published in:

Platelets, 2003, v. 14, n. 4, p. 225, doi. 10.1080/0953710031000118858

By:

Sun, Bing;
Tao, Lian;
Lin, Shihua;
Calingasan, Noel Y;
Li, Jess;
Tandon, Narendra N.;
Yoshitake, Masuhiro;
Kambayashi, Jun-ichi

Publication type:

Article

Coenzyme Q10 Decreases Amyloid Pathology and Improves Behavior in a Transgenic Mouse Model of Alzheimer's Disease.

Published in:

Journal of Alzheimer's Disease, 2011, v. 27, n. 1, p. 211, doi. 10.3233/JAD-2011-110209

By:

Dumont, Magali;
Kipiani, Khatuna;
Yu, Fangmin;
Wille, Elizabeth;
Katz, Maya;
Calingasan, Noel Y.;
Gouras, Gunnar K.;
Lin, Michael T.;
Beal, M. Flint

Publication type:

Article

Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease.

Published in:

2011

By:

Dumont M;
Kipiani K;
Yu F;
Wille E;
Katz M;
Calingasan NY;
Gouras GK;
Lin MT;
Beal MF;
Dumont, Magali;
Kipiani, Khatuna;
Yu, Fangmin;
Wille, Elizabeth;
Katz, Maya;
Calingasan, Noel Y;
Gouras, Gunnar K;
Lin, Michael T;
Beal, M Flint

Publication type:

journal article

Isotope-reinforced polyunsaturated fatty acids improve Parkinson's disease-like phenotype in rats overexpressing α-synuclein.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01090-6

By:

Beal, M. Flint;
Chiluwal, Jayandra;
Calingasan, Noel Y.;
Milne, Ginger L.;
Shchepinov, Mikhail S.;
Tapias, Victor

Publication type:

Article

Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 4, p. 686, doi. 10.1093/hmg/ddw429

By:

Fil, Daniel;
DeLoach, Abigail;
Yadav, Shilpi;
Alkam, Duah;
MacNicol, Melanie;
Singh, Awantika;
Compadre, Cesar M.;
Goellner, Joseph J.;
O'Brien, Charles A.;
Fahmi, Tariq;
Basnakian, Alexei G.;
Calingasan, Noel Y.;
Klessner, Jodi L.;
Beal, Flint M.;
Peters, Owen M.;
Metterville, Jake;
Brown Jr, Robert H.;
Ling, Karen K. Y.;
Rigo, Frank;
Ozdinler, P. Hande

Publication type:

Article

Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 11, p. 2269, doi. 10.1093/hmg/ddw095

By:

Chandra, Abhishek;
Sharma, Abhijeet;
Calingasan, Noel Y.;
White, Joshua M.;
Shurubor, Yevgeniya;
Yang, X. William;
Beal, M. Flint;
Johri, Ashu

Publication type:

Article

Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 2, p. 317, doi. 10.1093/hmg/ddv477

By:

Esmaeili, Mohammad A.;
Yadav, Shilpi;
Gupta, Ravi Kr.;
Waggoner, Garrett R.;
Deloach, Abigail;
Calingasan, Noel Y.;
Beal, M. Flint;
Kiaei, Mahmoud

Publication type:

Article

Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 23, p. 5091, doi. 10.1093/hmg/dds355

By:

Dumont, Magali;
Stack, Cliona;
Elipenahli, Ceyhan;
Jainuddin, Shari;
Gerges, Meri;
Starkova, Natalia;
Calingasan, Noel Y.;
Yang, Lichuan;
Tampellini, Davide;
Starkov, Anatoly A.;
Chan, Robin B.;
Di Paolo, Gilbert;
Pujol, Aurora;
Beal, M. Flint

Publication type:

Article

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 5, p. 1124, doi. 10.1093/hmg/ddr541

By:

Johri, Ashu;
Calingasan, Noel Y.;
Hennessey, Thomas M.;
Sharma, Abhijeet;
Yang, Lichuan;
Wille, Elizabeth;
Chandra, Abhishek;
Beal, M. Flint

Publication type:

Article

Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 16, p. 3190, doi. 10.1093/hmg/ddq229

By:

Chaturvedi, Rajnish K.;
Calingasan, Noel Y.;
Yang, Lichuan;
Hennessey, Thomas;
Johri, Ashu;
Beal, M. Flint

Publication type:

Article

Concordant Signaling Pathways Produced by Pesticide Exposure in Mice Correspond to Pathways Identified in Human Parkinson's Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036191

By:

Gollamudi, Seema;
Johri, Ashu;
Calingasan, Noel Y.;
Lichuan Yang;
Elemento, Olivier;
Beal, M. Flint

Publication type:

Article

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005757

By:

Lichuan Yang;
Calingasan, Noel Y.;
Thomas, Bobby;
Chaturvedi, Rajnish K.;
Kiaei, Mahmoud;
Wille, Elizabeth J.;
Liby, Karen T.;
Williams, Charlotte;
Royce, Darlene;
Risingsong, Renee;
Musiek, Eric S.;
Morrow, Jason D.;
Sporn, Michael;
Beal, M. Flint

Publication type:

Article

Metabolic Impairment Induces Oxidative Stress, Compromises Inflammatory Responses, and Inactivates a Key Mitochondrial Enzyme in Microglia.

Published in:

Journal of Neurochemistry, 1999, v. 72, n. 5, p. 1948, doi. 10.1046/j.1471-4159.1999.0721948.x

By:

Park, Larry C. H.;
Zhang, Hui;
Sheu, Kwan-Fu Rex;
Calingasan, Noel Y.;
Kristal, Bruce S.;
Lindsay, J. Gordon;
Gibson, Gary E.

Publication type:

Article

Protein-Bound Acrolein.

Published in:

Journal of Neurochemistry, 1999, v. 72, n. 2, p. 751, doi. 10.1046/j.1471-4159.1999.0720751.x

By:

Calingasan, Noel Y;
Uchida, Koji;
Gibson, Gary E

Publication type:

Article

Immunochemical Characterization of the Deficiency of the α-Ketoglutarate Dehydrogenase Complex in Thiamine-Deficient Rat Brain.

Published in:

Journal of Neurochemistry, 1998, v. 70, n. 3, p. 1143, doi. 10.1046/j.1471-4159.1998.70031143.x

By:

Sheu, Kwan-Fu Rex;
Calingasan, Noel Y.;
Lindsay, J. Gordon;
Gibson, Gary E.

Publication type:

Article

Regional Reductions of Transketolase in Thiamine-Deficient Rat Brain.

Published in:

Journal of Neurochemistry, 1996, v. 67, n. 2, p. 684, doi. 10.1046/j.1471-4159.1996.67020684.x

By:

Sheu, Kwan-Fu Rex;
Calingasan, Noel Y.;
Dienel, Gerald A.;
Baker, Harriet;
Jung, Eun-Hee;
Kim, Kwang-Soo;
Paoletti, Francesco;
Gibson, Gary E.

Publication type:

Article

Heterogeneous Expression of Transketolase in Rat Brain.

Published in:

Journal of Neurochemistry, 1995, v. 64, n. 3, p. 1034, doi. 10.1046/j.1471-4159.1995.64031034.x

By:

Calingasan, Noel Y.;
Sheu, Kwan-Fu Rex;
Baker, Harriet;
Jung, Eun-Hee;
Paoletti, Francesco;
Gibson, Gary E.

Publication type:

Article

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

Published in:

Nature Biotechnology, 2003, v. 21, n. 10, p. 1200, doi. 10.1038/nbt870

By:

Barberi, Tiziano;
Klivenyi, Peter;
Calingasan, Noel Y.;
Hyojin Lee, Noel Y.;
Kawamata, Hibiki;
Loonam, Kathleen;
Perrier, Anselme L.;
Bruses, Juan;
Rubio, Maria E.;
Topf, Norbert;
Tabar, Viviane;
Harrison, Neil L.;
Beal, M. Flint;
Moore, Malcolm A.S.;
Studer, Lorenz

Publication type:

Article

PGC-lα overexpression exacerbates ß-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.

Published in:

FASEB Journal, 2014, v. 28, n. 4, p. 1745, doi. 10.1096/fj.13-236331

By:

Dumont, Magali;
Stack, Cliona;
Elipenahli, Ceyhan;
Jainuddin, Shari;
Launay, Nathalie;
Gerges, Meri;
Starkova, Natalia;
Starkov, Anatoly A.;
Calingasan, Noel Y.;
Tampellini, Davide;
Pujo, Aurora;
Beai, M. Flint

Publication type:

Article

Combination therapy with Coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 5, p. 1427, doi. 10.1111/j.1471-4159.2009.06074.x

By:

Yang, Lichuan;
Calingasan, Noel Y.;
Wille, Elizabeth J.;
Cormier, Kerry;
Smith, Karen;
Ferrante, Robert J.;
Flint Beal, M.

Publication type:

Article

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer’s disease.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 2, p. 502, doi. 10.1111/j.1471-4159.2009.05970.x

By:

Dumont, Magali;
Wille, Elizabeth;
Calingasan, Noel Y.;
Tampellini, Davide;
Williams, Charlotte;
Gouras, Gunnar K.;
Liby, Karen;
Sporn, Michael;
Beal, M. Flint;
Lin, Michael T.

Publication type:

Article

Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.

Published in:

Journal of Neurochemistry, 2008, v. 104, n. 6, p. 1613, doi. 10.1111/j.1471-4159.2007.05097.x

By:

Cleren, Carine;
Yang, Lichuan;
Lorenzo, Beverly;
Calingasan, Noel Y.;
Schomer, Andrew;
Sireci, Anthony;
Wille, Elizabeth J.;
Beal, M. Flint

Publication type:

Article

The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2007, v. 102, n. 3, p. 991, doi. 10.1111/j.1471-4159.2007.04604.x

By:

Petri, Susanne;
Calingasan, Noel Y.;
Alsaied, Osama A.;
Wille, Elizabeth;
Kiaei, Mahmoud;
Friedman, Jonathan E.;
Baranova, Oxana;
Chavez, Juan C.;
Beal, M. Flint

Publication type:

Article

Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2006, v. 98, n. 4, p. 1141, doi. 10.1111/j.1471-4159.2006.04018.x

By:

Petri, Susanne;
Kiaei, Mahmoud;
Damiano, Maria;
Hiller, Andrew;
Wille, Elizabeth;
Manfredi, Giovanni;
Calingasan, Noel Y.;
Szeto, Hazel H.;
Beal, M. Flint

Publication type:

Article

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

Published in:

Journal of Neurochemistry, 2005, v. 94, n. 4, p. 995, doi. 10.1111/j.1471-4159.2005.03253.x

By:

Cleren, Carine;
Calingasan, Noel Y.;
Chen, Junya;
Beal, M. Flint

Publication type:

Article

Integrative role of cPLA2 with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2005, v. 93, n. 2, p. 403, doi. 10.1111/j.1471-4159.2005.03024.x

By:

Kiaei, Mahmoud;
Kipiani, Khatuna;
Petri, Susanne;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Beal, M. Flint

Publication type:

Article

Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

Published in:

Journal of Neurochemistry, 2004, v. 89, n. 5, p. 1308, doi. 10.1111/j.1471-4159.2004.02455.x

By:

Li, Feng;
Calingasan, Noel Y.;
Yu, Fangmin;
Mauck, William M.;
Toidze, Marine;
Almeida, Claudia G.;
Takahashi, Reisuke H.;
Carlson, George A.;
Beal, M. Flint;
Lin, Michael T.;
Gouras, Gunnar K.

Publication type:

Article

Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.

Published in:

Journal of Neurochemistry, 2004, v. 88, n. 6, p. 1352, doi. 10.1046/j.1471-4159.2003.02263.x

By:

Klivenyi, Peter;
Starkov, Anatoly A.;
Calingasan, Noel Y.;
Gardian, Gabrielle;
Browne, Susan E.;
Lichuan Yang, Susan E.;
Bubber, Parvesh;
Gibson, Gary E.;
Patel, Mulchand S.;
Beal, M. Flint

Publication type:

Article

Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2003, v. 85, n. 1, p. 142, doi. 10.1046/j.1471-4159.2003.01639.x

By:

Wu, Annie S.;
Kiaei, Mahmoud;
Aguirre, Norberto;
Crow, John P.;
Calingasan, Noel Y.;
Browne, Susan E.;
Beal, M. Flint

Publication type:

Article

Metabolic Impairment Elicits Brain Cell Type-Selective Changes in Oxidative Stress and Cell Death in Culture.

Published in:

Journal of Neurochemistry, 2000, v. 74, n. 1, p. 114, doi. 10.1046/j.1471-4159.2000.0740114.x

By:

Park, Larry C. H.;
Calingasan, Noel Y.;
Uchida, Koji;
Zhang, Hui;
Gibson, Gary E.

Publication type:

Article