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Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47957-3
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- Publication type:
- Article
UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39591-2
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- Publication type:
- Article
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD<sub>4</sub>-selective WNT surrogate in mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37689-1
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- Publication type:
- Article
NaRnEA: An Information Theoretic Framework for Gene Set Analysis.
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- Entropy, 2023, v. 25, n. 3, p. 542, doi. 10.3390/e25030542
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- Publication type:
- Article
War, Sanctions, Deglobalization: Which Comes First?
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- Revista Brasileira de Política Internacional, 2023, v. 66, n. 1, p. 1, doi. 10.1590/0034-7329202300104
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- Publication type:
- Article
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.80083
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- Publication type:
- Article
A Patient‐to‐Model‐to‐Patient (PMP) Cancer Drug Discovery Protocol for Identifying and Validating Therapeutic Agents Targeting Tumor Regulatory Architecture.
- Published in:
- Current Protocols, 2022, v. 2, n. 9, p. 1, doi. 10.1002/cpz1.544
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- Publication type:
- Article
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03663-8
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- Publication type:
- Article
329 Longitudinal immune profiling reveals unique myeloid and T cell phenotypes associated with spontaneous immunoediting in a novel prostate tumor model.
- Published in:
- 2022
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- Publication type:
- Abstract
Fimepinostat (CUDC‐907) in patients with relapsed/refractory diffuse large B cell and high‐grade B‐cell lymphoma: report of a phase 2 trial and exploratory biomarker analyses.
- Published in:
- British Journal of Haematology, 2021, v. 195, n. 2, p. 201, doi. 10.1111/bjh.17730
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- Publication type:
- Article
Phase I/II trial of ruxolitinib in combination with trastuzumab in metastatic HER2 positive breast cancer.
- Published in:
- Breast Cancer Research & Treatment, 2021, v. 189, n. 1, p. 177, doi. 10.1007/s10549-021-06306-4
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- Publication type:
- Article
Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.
- Published in:
- Nature Biotechnology, 2021, v. 39, n. 2, p. 215, doi. 10.1038/s41587-020-0652-7
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- Publication type:
- Article
Generation of pralatrexate resistant T‐cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers.
- Published in:
- Genes, Chromosomes & Cancer, 2020, v. 59, n. 11, p. 639, doi. 10.1002/gcc.22884
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- Publication type:
- Article
The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.52707
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- Publication type:
- Article
Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67310-0
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- Publication type:
- Article
SJARACNe: a scalable software tool for gene network reverse engineering from big data.
- Published in:
- Bioinformatics, 2019, v. 35, n. 12, p. 2165, doi. 10.1093/bioinformatics/bty907
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- Publication type:
- Article
Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis.
- Published in:
- PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0208646
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- Publication type:
- Article
NSD2 is a conserved driver of metastatic prostate cancer progression.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07511-4
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- Publication type:
- Article
Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05729-w
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- Publication type:
- Article
The number of titrated microRNA species dictates ceRNA regulation.
- Published in:
- Nucleic Acids Research, 2018, v. 46, n. 9, p. 4354, doi. 10.1093/nar/gky286
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- Publication type:
- Article
Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03843-3
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- Publication type:
- Article
ZCCHC17 is a master regulator of synaptic gene expression in Alzheimer's disease.
- Published in:
- Bioinformatics, 2018, v. 34, n. 3, p. 367, doi. 10.1093/bioinformatics/btx608
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- Publication type:
- Article
Systematic, network-based characterization of therapeutic target inhibitors.
- Published in:
- PLoS Computational Biology, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005599
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- Publication type:
- Article
Accelerated parallel algorithm for gene network reverse engineering.
- Published in:
- BMC Systems Biology, 2017, v. 11, p. 85, doi. 10.1186/s12918-017-0458-5
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- Publication type:
- Article
PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00136-z
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- Publication type:
- Article
High-throughput validation of ceRNA regulatory networks.
- Published in:
- BMC Genomics, 2017, v. 18, p. 1, doi. 10.1186/s12864-017-3790-7
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- Publication type:
- Article
Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers.
- Published in:
- 2017
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- Publication type:
- journal article
A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue.
- Published in:
- Nature Communications, 2017, v. 8, n. 4, p. 14662, doi. 10.1038/ncomms14662
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- Publication type:
- Article
CTD<sup>2</sup> Dashboard: a searchable web interface to connect validated results from the Cancer Target Discovery and Development Network.
- Published in:
- Database: The Journal of Biological Databases & Curation, 2017, v. 2017, n. 1, p. 1, doi. 10.1093/database/bax054
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- Publication type:
- Article
A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma.
- Published in:
- Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0366-0
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- Publication type:
- Article
Correction: Inferring Protein Modulation from Gene Expression Data Using Conditional Mutual Information.
- Published in:
- 2016
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- Publication type:
- Correction Notice
ARACNe-AP: gene network reverse engineering through adaptive partitioning inference of mutual information.
- Published in:
- Bioinformatics, 2016, v. 32, n. 14, p. 2233, doi. 10.1093/bioinformatics/btw216
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- Publication type:
- Article
Detection and removal of spatial bias in multiwell assays.
- Published in:
- Bioinformatics, 2016, v. 32, n. 13, p. 1959, doi. 10.1093/bioinformatics/btw092
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- Publication type:
- Article
ScreenBEAM: a novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modeling.
- Published in:
- Bioinformatics, 2016, v. 32, n. 2, p. 260, doi. 10.1093/bioinformatics/btv556
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- Publication type:
- Article
DIGGIT: a Bioconductor package to infer genetic variants driving cellular phenotypes.
- Published in:
- Bioinformatics, 2015, v. 31, n. 24, p. 4032, doi. 10.1093/bioinformatics/btv499
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- Publication type:
- Article
HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers.
- Published in:
- 2015
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- Publication type:
- journal article
Identification of neurodegenerative factors using translatome-regulatory network analysis.
- Published in:
- Nature Neuroscience, 2015, v. 18, n. 9, p. 1325, doi. 10.1038/nn.4070
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- Publication type:
- Article
Toward understanding and exploiting tumor heterogeneity.
- Published in:
- Nature Medicine, 2015, v. 21, n. 8, p. 846, doi. 10.1038/nm.3915
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- Publication type:
- Article
ABC Transporters and the Proteasome Complex Are Implicated in Susceptibility to Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis across Multiple Drugs.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131038
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- Publication type:
- Article
Direct ChIP-Seq significance analysis improves target prediction.
- Published in:
- BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/1471-2164-16-S5-S4
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- Publication type:
- Article
The Cyni framework for network inference in Cytoscape.
- Published in:
- 2015
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- Publication type:
- Product Review
Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks.
- Published in:
- Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-015-0593-5
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- Publication type:
- Article
Assembly and Interrogation of Alzheimer’s Disease Genetic Networks Reveal Novel Regulators of Progression.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120352
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- Publication type:
- Article
Interrogation of a Context-Specific Transcription Factor Network Identifies Novel Regulators of Pluripotency.
- Published in:
- Stem Cells, 2015, v. 33, n. 2, p. 367, doi. 10.1002/stem.1870
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- Publication type:
- Article
A community computational challenge to predict the activity of pairs of compounds.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 12, p. 1213, doi. 10.1038/nbt.3052
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- Publication type:
- Article
Predicting protein networks in cancer.
- Published in:
- Nature Genetics, 2014, v. 46, n. 12, p. 1252, doi. 10.1038/ng.3156
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- Publication type:
- Article
Toward better benchmarking: challenge-based methods assessment in cancer genomics.
- Published in:
- Genome Biology, 2014, v. 15, n. 9, p. 462, doi. 10.1186/s13059-014-0462-7
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- Publication type:
- Article
Inferring Protein Modulation from Gene Expression Data Using Conditional Mutual Information.
- Published in:
- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109569
- By:
- Publication type:
- Article
Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. 9, p. 1210, doi. 10.1093/neuonc/nou026
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- Publication type:
- Article
Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-26
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- Publication type:
- Article