Works matching AU Caldwell, Ruth B.

Results: 65

Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00277

By:

Fouda, Abdelrahman Y.;
Eldahshan, Wael;
Narayanan, S. Priya;
Caldwell, R. William;
Caldwell, Ruth B.

Publication type:

Article

Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair.

Published in:

Cell Death & Disease, 2022, v. 13, n. 8, p. 1, doi. 10.1038/s41419-022-05196-8

By:

Fouda, Abdelrahman Y.;
Xu, Zhimin;
Suwanpradid, Jutamas;
Rojas, Modesto;
Shosha, Esraa;
Lemtalsi, Tahira;
Patel, Chintan;
Xing, Ji;
Zaidi, Syed A.;
Zhi, Wenbo;
Stansfield, Brain K.;
Cheng, Paul Ning-Man;
Narayanan, S. Priya;
Caldwell, R. William;
Caldwell, Ruth B.

Publication type:

Article

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses.

Published in:

Cell Death & Disease, 2018, v. 9, n. 10, p. 1, doi. 10.1038/s41419-018-1051-6

By:

Fouda, Abdelrahman Y.;
Xu, Zhimin;
Shosha, Esraa;
Lemtalsi, Tahira;
Chen, Jijun;
Toque, Haroldo A.;
Tritz, Rebekah;
Cui, Xuezhi;
Stansfield, Brian K.;
Huo, Yuqing;
Rodriguez, Paulo C.;
Smith, Sylvia B.;
Caldwell, R. William;
Narayanan, S. Priya;
Caldwell, Ruth B.

Publication type:

Article

Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury.

Published in:

Cell Death & Disease, 2016, v. 7, n. 11, p. e2483, doi. 10.1038/cddis.2016.295

By:

Shosha, Esraa;
Xu, Zhimin;
Yokota, Harumasa;
Saul, Alan;
Rojas, Modesto;
Caldwell, R William;
Caldwell, Ruth B;
Narayanan, S Priya

Publication type:

Article

Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush.

Published in:

Cell Death & Disease, 2023, v. 14, n. 10, p. 1, doi. 10.1038/s41419-023-06180-6

By:

Zaidi, Syed A. H.;
Xu, Zhimin;
Lemtalsi, Tahira;
Sandow, Porsche;
Athota, Sruthi;
Liu, Fang;
Haigh, Stephen;
Huo, Yuqing;
Narayanan, S. Priya;
Fulton, David J. R.;
Rojas, Modesto A.;
Fouda, Abdelrahman Y.;
Caldwell, Robert W.;
Caldwell, Ruth B.

Publication type:

Article

The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury.

Published in:

Cell Death & Disease, 2023, v. 14, n. 9, p. 1, doi. 10.1038/s41419-023-06147-7

By:

Shosha, Esraa;
Shahror, Rami A.;
Morris, Carol A.;
Xu, Zhimin;
Lucas, Rudolf;
McGee-Lawrence, Meghan E.;
Rusch, Nancy J.;
Caldwell, Ruth B.;
Fouda, Abdelrahman Y.

Publication type:

Article

Inflammation and diabetic retinal microvascular complications.

Published in:

Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2011, v. 2, n. 2, p. 96, doi. 10.4103/0975-3583.83035

By:

Wenbo Zhang;
Hua Liu;
Al-Shabrawey, Mohamed;
Caldwell, Robert W.;
Caldwell, Ruth B.

Publication type:

Article

The role of RhoA/Rho kinase pathway in endothelial dysfunction.

Published in:

Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2010, v. 1, n. 4, p. 165

By:

Lin Yao;
Romero, Maritza J.;
Toque, Haroldo A.;
Guang Yang;
Caldwell, Ruth B.;
William Caldwell, R.

Publication type:

Article

Correction: Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0127110

By:

Bhatta, Anil;
Yao, Lin;
Toque, Haroldo A.;
Shatanawi, Alia;
Xu, Zhimin;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121727

By:

Bhatta, Anil;
Yao, Lin;
Toque, Haroldo A.;
Shatanawi, Alia;
Xu, Zhimin;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Arginase 2 Deficiency Prevents Oxidative Stress and Limits Hyperoxia-Induced Retinal Vascular Degeneration.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0110604

By:

Suwanpradid, Jutamas;
Rojas, Modesto;
Behzadian, M. Ali;
Caldwell, R. William;
Caldwell, Ruth B.

Publication type:

Article

Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084357

By:

Rojas, Modesto;
Zhang, Wenbo;
Xu, Zhimin;
Lemtalsi, Tahira;
Chandler, Phillip;
Toque, Haroldo A.;
Caldwell, Robert W.;
Caldwell, Ruth B.

Publication type:

Article

Akita Spontaneously Type 1 Diabetic Mice Exhibit Elevated Vascular Arginase and Impaired Vascular Endothelial and Nitrergic Function.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072277

By:

Toque, Haroldo A.;
Nunes, Kenia P.;
Yao, Lin;
Xu, Zhimin;
Kondrikov, Dmitry;
Su, Yunchao;
Webb, R. Clinton;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071868

By:

El-Remessy, Azza B.;
Franklin, Telina;
Ghaley, Nagla;
Yang, Jinling;
Brands, Michael W.;
Caldwell, Ruth B.;
Behzadian, Mohamed Ali

Publication type:

Article

Arginase 2 Deletion Reduces Neuro-Glial Injury and Improves Retinal Function in a Model of Retinopathy of Prematurity.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022460

By:

Narayanan, Subhadra P.;
Suwanpradid, Jutamas;
Saul, Alan;
Zhimin Xu;
Still, Amber;
Caldwell, Robert W.;
Caldwell, Ruth B.

Publication type:

Article

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

Published in:

Cardiovascular Research, 2013, v. 97, n. 3, p. 509, doi. 10.1093/cvr/cvs371

By:

Yao, Lin;
Chandra, Surabhi;
Toque, Haroldo A.;
Bhatta, Anil;
Rojas, Modesto;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Hyperoxia‐induced Microvascular Injury Involves Arginase 2‐induced Oxidative Stress, Microglia/Macrophage Activation and Constitutive NOS Downregulation.

Published in:

FASEB Journal, 2013, v. 27, p. 875.7, doi. 10.1096/fasebj.27.1_supplement.875.7

By:

Suwanpradid, Jutamas;
Caldwell, R. William;
Caldwell, Ruth B.

Publication type:

Article

Diabetes/high glucose induced arginase increases arterial smooth muscle cell proliferation and collagen synthesis/fibrosis through ornithine decarboxylase and ornithine aminotransferase pathways.

Published in:

FASEB Journal, 2013, v. 27, p. 651.2, doi. 10.1096/fasebj.27.1_supplement.651.2

By:

Bhatta, Anil;
Toque, Haroldo A;
Caldwell, Ruth B;
Caldwell, R. William

Publication type:

Article

Diabetes-induced arginase activity contributes to vascular and renal fibrosis and dysfunction.

Published in:

FASEB Journal, 2008, v. 22, p. 643, doi. 10.1096/fasebj.22.2_supplement.643

By:

Romero, Maritza Josefina;
Iddings, Jennifer;
Platt, Daniel;
Caldwell, Ruth B.;
Caldwell, Robert W.

Publication type:

Article

VEGF differentially activates STAT3 in microvascular endothelial cells¹.

Published in:

FASEB Journal, 2003, v. 17, n. 11, p. 1562, doi. 10.1096/fj.02-1084fje

By:

Bartoli, Manuela;
Platt, Dan;
Lemtalsi, Tahira;
Xiaolin Gu;
Brooks, Steven E.;
Marrero, Mario B.;
Caldwell, Ruth B.

Publication type:

Article

VEGF‐induced paracellular permeability in cultured endothelial cells involves urokinase and its receptor.

Published in:

FASEB Journal, 2003, v. 17, n. 6, p. 752, doi. 10.1096/fj.02-0484fje

By:

Behzadian, M. Ali;
Windsor, L. Jack;
Ghaly, Nagla;
Liou, Gregory;
Tsai, Nai‐Tse;
Caldwell, Ruth B.

Publication type:

Article

Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.

Published in:

Diabetes/Metabolism Research & Reviews, 2003, v. 19, n. 6, p. 442, doi. 10.1002/dmrr.415

By:

Ruth B. Caldwell;
Manuela Bartoli;
M. Ali Behzadian;
Azza E. B. El-Remessy;
Mohamed Al-Shabrawey;
Daniel H. Platt;
R. William Caldwell

Publication type:

Article

Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice.

Published in:

Science Translational Medicine, 2024, v. 16, n. 737, p. 1, doi. 10.1126/scitranslmed.adk3868

By:

Yang, Qiuhua;
Cai, Yongfeng;
Ma, Qian;
Xiong, Albert;
Xu, Peishan;
Zhang, Zhidan;
Xu, Jiean;
Zhou, Yaqi;
Liu, Zhiping;
Zhao, Dingwei;
Asara, John;
Li, Wei;
Shi, Huidong;
Caldwell, Ruth B.;
Sodhi, Akrit;
Huo, Yuqing

Publication type:

Article

Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche.

Published in:

Science Translational Medicine, 2020, v. 12, n. 555, p. 1, doi. 10.1126/scitranslmed.aay1371

By:

Liu, Zhiping;
Xu, Jiean;
Ma, Qian;
Zhang, Xiaoyu;
Yang, Qiuhua;
Wang, Lina;
Cao, Yapeng;
Xu, Zhimin;
Tawfik, Amany;
Sun, Ye;
Weintraub, Neal L.;
Fulton, David J.;
Hong, Mei;
Dong, Zheng;
Smith, Lois E. H.;
Caldwell, Ruth B.;
Sodhi, Akrit;
Huo, Yuqing

Publication type:

Article

Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02700-5

By:

Zaidi, Syed A. H.;
Lemtalsi, Tahira;
Xu, Zhimin;
Santana, Isabella;
Sandow, Porsche;
Labazi, Leila;
Caldwell, Robert W.;
Caldwell, Ruth B.;
Rojas, Modesto A.

Publication type:

Article

Endothelial nitric oxide synthase is a site of superoxide synthesis in endothelial cells treated with glyceryl trinitrate.

Published in:

2000

By:

Kaesemeyer, Wayne H;
Ogonowski, Alison A;
Jin, Liming;
Caldwell, Ruth B;
Caldwell, Robert W;
Kaesemeyer, W H;
Ogonowski, A A;
Jin, L;
Caldwell, R B;
Caldwell, R W

Publication type:

journal article

Role of L-arginine in the vascular actions and development of tolerance to nitroglycerin.

Published in:

2000

By:

Abou-Mohamed, Gamal;
Kaesemeyer, Wayne H;
Caldwell, Ruth B;
Caldwell, Robert W;
Abou-Mohamed, G;
Kaesemeyer, W H;
Caldwell, R B;
Caldwell, R W

Publication type:

journal article

Toxicity and Cellular Uptake of Gold Nanorods in Vascular Endothelium and Smooth Muscles of Isolated Rat Blood Vessel: Importance of Surface Modification.

Published in:

Small, 2012, v. 8, n. 8, p. 1270, doi. 10.1002/smll.201101948

By:

Alkilany, Alaaldin M.;
Shatanawi, Alia;
Kurtz, Timothy;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Netrin-1 is a novel regulator of vascular endothelial function in diabetes.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186734

By:

Toque, Haroldo A.;
Fernandez-Flores, Aracely;
Mohamed, Riyaz;
Caldwell, Ruth B.;
Ramesh, Ganesan;
Caldwell, R. William

Publication type:

Article

Correction: Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway.

Published in:

2017

By:

El-Remessy, Azza B.;
Franklin, Telina;
Ghaley, Nagla;
Yang, Jinling;
Brands, Michael W.;
Caldwell, Ruth B.;
Behzadian, Mohamed Ali

Publication type:

Correction Notice

Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-β.

Published in:

Glia (0894-1491), 1998, v. 24, n. 2, p. 216, doi. 10.1002/(SICI)1098-1136(199810)24:2<216::AID-GLIA6>3.0.CO;2-1

By:

Behzadian, M. Ali;
Wang, Xi-Liang;
Shabrawey, Mohammed;
Caldwell, Ruth B.

Publication type:

Article

Angiostatic role or astrocytes: Suppression of vascular endothelial cell growth by TGF-β and other inhibitory factor(s).

Published in:

Glia (0894-1491), 1995, v. 15, n. 4, p. 480, doi. 10.1002/glia.440150411

By:

Behzadian, M. Ali;
Wang, Xi-Liang;
Jiang, Baoen;
Caldwell, Ruth B.

Publication type:

Article

Astrocytes modulate retinal vasculogenesis: Effects on endothelial cell differentiation.

Published in:

Glia (0894-1491), 1995, v. 15, n. 1, p. 1, doi. 10.1002/glia.440150102

By:

Jiang, Baoen;
Alibezhadian, M.;
Caldwell, Ruth B.

Publication type:

Article

Müller cell changes precede vascularization of the pigment epithelium in the dystrophic rat retina.

Published in:

Glia (0894-1491), 1990, v. 3, n. 6, p. 464, doi. 10.1002/glia.440030605

By:

Roque, Rouel S.;
Caldwell, Ruth B.

Publication type:

Article

Superior colliculus neurons which project to the cat lateral posterior nucleus have varying morphologies.

Published in:

Journal of Comparative Neurology, 1981, v. 203, n. 1, p. 53, doi. 10.1002/cne.902030106

By:

Caldwell, Ruth B.;
Mize, R. Ranney

Publication type:

Article

Serum Opens Tight Junctions and Reduces ZO-1 Protein in Retinal Epithelial Cells.

Published in:

Journal of Neurochemistry, 1997, v. 69, n. 2, p. 859, doi. 10.1046/j.1471-4159.1997.69020859.x

By:

Chang, Chih-wei;
Wang, Xiliang;
Caldwell, Ruth B.

Publication type:

Article

Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 12, p. 8589, doi. 10.1007/s12035-019-01691-w

By:

Palani, Chithra D.;
Fouda, Abdelrahman Y.;
Liu, Fang;
Xu, Zhimin;
Mohamed, Eslam;
Giri, Shailedra;
Smith, Sylvia B.;
Caldwell, Ruth B.;
Narayanan, S. Priya

Publication type:

Article

Protection against Doxorubicin-Induced Cardiotoxicity through Modulating iNOS/ARG 2 Balance by Electroacupuncture at PC6.

Published in:

Oxidative Medicine & Cellular Longevity, 2021, p. 1, doi. 10.1155/2021/6628957

By:

Wang, Jingya;
Yao, Lin;
Wu, Xiaoli;
Guo, Qi;
Sun, Shengxuan;
Li, Jie;
Shi, Guoqi;
Caldwell, Ruth B.;
Caldwell, R. William;
Chen, Yongjun

Publication type:

Article

Protein Kinase C-α and Arginase I Mediate Pneumolysin-Induced Pulmonary Endothelial Hyperpermeability.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2012, v. 47, n. 4, p. 445, doi. 10.1165/rcmb.2011-0332OC

By:

Lucas, Rudolf;
Guang Yang;
Gorshkov, Boris A.;
Zemskov, Evgeny A.;
Sridhar, Supriya;
Umapathy, Nagavedi S.;
Jezierska-Drutel, Agnieszka;
Alieva, Irina B.;
Leustik, Martin;
Hossain, Hamid;
Fischer, Bernhard;
Catravas, John D.;
Verin, Alexander D.;
Pittet, Jean-Francois;
Caldwell, Ruth B.;
Mitchell, Timothy J.;
Cederbaum, Stephen D.;
Fulton, David J.;
Matthay, Michael A.;
Caldwell, Robert W.

Publication type:

Article

Pharmacological Modulation of β-Catenin Preserves Endothelial Barrier Integrity and Mitigates Retinal Vascular Permeability and Inflammation.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 22, p. 7145, doi. 10.3390/jcm12227145

By:

Rudraraju, Madhuri;
Shan, Shengshuai;
Liu, Fang;
Tyler, Jennifer;
Caldwell, Ruth B.;
Somanath, Payaningal R.;
Narayanan, S. Priya

Publication type:

Article

Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 425, doi. 10.3390/jcm9020425

By:

Shosha, Esraa;
Fouda, Abdelrahman Y.;
Narayanan, S. Priya;
Caldwell, R. William;
Caldwell, Ruth B.

Publication type:

Article

Pharmacological Inhibition of Spermine Oxidase Reduces Neurodegeneration and Improves Retinal Function in Diabetic Mice.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 340, doi. 10.3390/jcm9020340

By:

Liu, Fang;
Saul, Alan B.;
Pichavaram, Prahalathan;
Xu, Zhimin;
Rudraraju, Madhuri;
Somanath, Payaningal R.;
Smith, Sylvia B.;
Caldwell, Ruth B.;
Narayanan, S. Priya

Publication type:

Article

Role of Arginase 2 in Murine Retinopathy Associated with Western Diet-Induced Obesity.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 317, doi. 10.3390/jcm9020317

By:

Atawia, Reem T.;
Bunch, Katharine L.;
Fouda, Abdelrahman Y.;
Lemtalsi, Tahira;
Eldahshan, Wael;
Xu, Zhimin;
Saul, Alan;
Elmasry, Khaled;
Al-Shabrawey, Mohamed;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

L-citrulline protects from kidney damage in type 1 diabetic mice.

Published in:

Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00480

By:

Romero, Maritza J.;
Lin Yao;
Sridhar, Supriya;
Bhatta, Anil;
Huijuan Dou;
Ramesh, Ganesan;
Brands, Michael W.;
Pollock, David M.;
Caldwell, Ruth B.;
Cederbaum, Stephen D.;
Head, C. Alvin;
Bagi, Zsolt;
Lucas, Rudolf;
Caldwell, Robert W.

Publication type:

Article

Arginase 1 mediates increased blood pressure and contributes to vascular endothelial dysfunction in deoxycorticosterone acetate-salt hypertension.

Published in:

Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00219

By:

Toque, Haroldo A.;
Nunes, Kenia P.;
Rojas, Modesto;
Bhatta, Anil;
Yao, Lin;
Xu, Zhimin;
Romero, Maritza J.;
ClintonWebb, R.;
Caldwell, Ruth B.;
Caldwell, R. William

Publication type:

Article

Arginase as a mediator of diabetic retinopathy.

Published in:

Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00173

By:

Patel, Chintan;
Rojas, Modesto;
Priya Narayanan, S.;
Wenbo Zhang;
Zhimin Xu;
Tahira Lemtalsi;
Kanjana Jittiporn;
William Caldwell, R.;
Caldwell, Ruth B.

Publication type:

Article

Suppression of myeloid PFKFB3-driven glycolysis protects mice from choroidal neovascularization.

Published in:

2022

By:

Liu, Zhiping;
Mao, Xiaoxiao;
Yang, Qiuhua;
Zhang, Xiaoyu;
Xu, Jiean;
Ma, Qian;
Zhou, Yaqi;
Da, Qingen;
Cai, Yongfeng;
Sopeyin, Anu;
Dong, Zheng;
Hong, Mei;
Caldwell, Ruth B.;
Sodhi, Akrit;
Huo, Yuqing

Publication type:

journal article

Modulation of VEGF production by pH and glucose in retinal Müller cells.

Published in:

Current Eye Research, 1998, v. 17, n. 9, p. 875, doi. 10.1076/ceyr.17.9.875.5134

By:

Brooks, Steven E.;
Gu, Xiaolin;
Kaufmann, Paul M.;
Marcus, Dennis M.;
Caldwell, Ruth B.

Publication type:

Article

Lectin-Ferritin Binding on Spontaneously Diabetic and Control Rat Retinal Microvasculature.

Published in:

Current Eye Research, 1989, v. 8, n. 3, p. 271, doi. 10.3109/02713688908997569

By:

Fitzgerald, Malinda E. C.;
Caldwell, Ruth B.

Publication type:

Article

Filipin and digitonin studies of cell membrane changes during junction breakdown in the dystrophic rat retinal pigment epithelium.

Published in:

Current Eye Research, 1987, v. 6, n. 3, p. 515, doi. 10.3109/02713688709025208

By:

Caldwell, Ruth B.

Publication type:

Article