Works by Cai, Demin

Results: 49

Probiotic Lactobacillus johnsonii Reduces Intestinal Inflammation and Rebalances Splenic Treg/Th17 Responses in Dextran Sulfate Sodium-Induced Colitis.

Published in:

Antioxidants, 2025, v. 14, n. 4, p. 433, doi. 10.3390/antiox14040433

By:

Liu, Hao-Yu;
Li, Shicheng;
Ogamune, Kennedy Jerry;
Yuan, Peng;
Shi, Xinyu;
Ennab, Wael;
Ahmed, Abdelkareem A.;
Kim, In Ho;
Hu, Ping;
Cai, Demin

Publication type:

Article

Dietary Organic Zinc Supplementation Modifies the Oxidative Genes via RORγ and Epigenetic Regulations in the Ileum of Broiler Chickens Exposed to High-Temperature Stress.

Published in:

Antioxidants, 2024, v. 13, n. 9, p. 1079, doi. 10.3390/antiox13091079

By:

Adam, Saber Y.;
Muniyappan, Madesh;
Huang, Hao;
Ennab, Wael;
Liu, Hao-Yu;
Ahmed, Abdelkareem A.;
Sun, Ming-an;
Dessie, Tadelle;
Kim, In Ho;
Hu, Yun;
Luo, Xugang;
Cai, Demin

Publication type:

Article

Hepatic Anti-Oxidative Genes CAT and GPX4 Are Epigenetically Modulated by RORγ/NRF2 in Alphacoronavirus-Exposed Piglets.

Published in:

Antioxidants, 2023, v. 12, n. 6, p. 1305, doi. 10.3390/antiox12061305

By:

Gu, Haotian;
Liu, Yaya;
Zhao, Yahui;
Qu, Huan;
Li, Yanhua;
Ahmed, Abdelkareem A.;
Liu, Hao-Yu;
Hu, Ping;
Cai, Demin

Publication type:

Article

Lactoferrin Restores the Deoxynivalenol-Impaired Spermatogenesis and Blood–Testis Barrier Integrity via Improving the Antioxidant Capacity and Modifying the Cell Adhesion and Inflammatory Response.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 152, doi. 10.3390/antiox12010152

By:

Li, Zhaojian;
Zhao, Yahui;
Zong, Qiufang;
Hu, Ping;
Bao, Wenbin;
Liu, Hao-Yu;
Cai, Demin

Publication type:

Article

Zinc intake ameliorates intestinal morphology and oxidative stress of broiler chickens under heat stress.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1308907

By:

Ping Hu;
Kaiqi Li;
Xiaoxu Peng;
Tongjia Yao;
Chuyang Zhu;
Haotian Gu;
Hao-Yu Liu;
Ming-an Sun;
Yun Hu;
Wael Ennab;
Xugang Luo;
Demin Cai

Publication type:

Article

Curcumin derived from medicinal homologous foods: its main signals in immunoregulation of oxidative stress, inflammation, and apoptosis.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1233652

By:

Ping Hu;
Kaiqi Li;
Xiao-Xu Peng;
Yufei Kan;
Tong-Jia Yao;
Zi-Yu Wang;
Zhaojian Li;
Hao-Yu Liu;
Demin Cai

Publication type:

Article

Maternal high-protein diet modulates hepatic growth axis in weaning piglets by reprogramming the IGFBP-3 gene.

Published in:

European Journal of Nutrition, 2020, v. 59, n. 6, p. 2497, doi. 10.1007/s00394-019-02097-z

By:

Cong, Rihua;
Qu, Xiaoli;
Zhang, Hui;
Hu, Yongling;
Ye, Silin;
Cai, Demin;
Li, Xian;
Liu, Hao-Yu

Publication type:

Article

Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation.

Published in:

European Journal of Nutrition, 2018, v. 57, n. 3, p. 991, doi. 10.1007/s00394-017-1383-5

By:

Pan, Shifeng;
Jia, Yimin;
Yang, Xiaojing;
Cai, Demin;
Liu, Zhiqing;
Song, Haogang;
Zhao, Ruqian

Publication type:

Article

Epigenetic and SP1-mediated regulation is involved in the repression of galactokinase 1 gene in the liver of neonatal piglets born to betaine-supplemented sows.

Published in:

European Journal of Nutrition, 2017, v. 56, n. 5, p. 1899, doi. 10.1007/s00394-016-1232-y

By:

Cai, Demin;
Yuan, Mengjie;
Liu, Haoyu;
Han, Zhengqiang;
Pan, Shifeng;
Yang, Yang;
Zhao, Ruqian

Publication type:

Article

Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets.

Published in:

European Journal of Nutrition, 2016, v. 55, n. 3, p. 1307, doi. 10.1007/s00394-015-0949-3

By:

Jia, Yimin;
Gao, Guichao;
Song, Haogang;
Cai, Demin;
Yang, Xiaojing;
Zhao, Ruqian

Publication type:

Article

Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.

Published in:

European Journal of Nutrition, 2015, v. 54, n. 7, p. 1201, doi. 10.1007/s00394-014-0799-4

By:

Li, Xi;
Sun, Qinwei;
Li, Xian;
Cai, Demin;
Sui, Shiyan;
Jia, Yimin;
Song, Haogang;
Zhao, Ruqian

Publication type:

Article

Melatonin Modulates ZAP70 and CD40 Transcripts via Histone Modifications in Canine Ileum Epithelial Cells.

Published in:

Veterinary Sciences, 2025, v. 12, n. 2, p. 87, doi. 10.3390/vetsci12020087

By:

Hong, Jian;
Adam, Saber Y.;
Wang, Shiqi;
Huang, Hao;
Kim, In Ho;
Ahmed, Abdelkareem A.;
Liu, Hao-Yu;
Cai, Demin

Publication type:

Article

The Immunotherapy and Immunosuppressive Signaling in Therapy-Resistant Prostate Cancer.

Published in:

Biomedicines, 2022, v. 10, n. 8, p. N.PAG, doi. 10.3390/biomedicines10081778

By:

Xu, Pengfei;
Wasielewski, Logan J.;
Yang, Joy C.;
Cai, Demin;
Evans, Christopher P.;
Murphy, William J.;
Liu, Chengfei

Publication type:

Article

GR-mediated FTO transactivation induces lipid accumulation in hepatocytes via demethylation of m<sup>6</sup>A on lipogenic mRNAs.

Published in:

RNA Biology, 2020, v. 17, n. 7, p. 930, doi. 10.1080/15476286.2020.1736868

By:

Hu, Yun;
Feng, Yue;
Zhang, Luchu;
Jia, Yimin;
Cai, Demin;
Qian, Shu-Bing;
Du, Min;
Zhao, Ruqian

Publication type:

Article

Lithocholic Acid Alleviates Deoxynivalenol-Induced Lethal Cholesterol Metabolic Abnormalities in IPI-2I Cells.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/metabo12070659

By:

Li, Yanwei;
Gu, Fang;
Gu, Haotian;
Hu, Ping;
Liu, Hui-Xin;
Cai, Demin

Publication type:

Article

Comprehensive Annotation and Expression Profiling of C2H2 Zinc Finger Transcription Factors across Chicken Tissues.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10525, doi. 10.3390/ijms251910525

By:

Chen, Shuai;
Jiang, Jiayao;
Liang, Wenxiu;
Tang, Yuchen;
Lyu, Renzhe;
Hu, Yun;
Cai, Demin;
Luo, Xugang;
Sun, Mingan

Publication type:

Article

A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15548, doi. 10.3390/ijms232415548

By:

Li, Chenxi;
Chen, Xuan;
Hu, Jingbo;
Jiang, Daoyuan;
Cai, Demin;
Li, Yanhua

Publication type:

Article

The Circadian Physiology: Implications in Livestock Health.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2111, doi. 10.3390/ijms22042111

By:

Li, Hao;
Li, Kaiqi;
Zhang, Kexin;
Li, Yanwei;
Gu, Haotian;
Liu, Haoyu;
Yang, Zhangping;
Cai, Demin;
Brown, Gregory Michael

Publication type:

Article

Phytogenics in swine nutrition and their effects on growth performance, nutrient utilization, gut health, and meat quality: a review.

Published in:

Stress Biology, 2025, v. 5, n. 1, p. 1, doi. 10.1007/s44154-024-00209-2

By:

Madesh, Muniyappan;
Yan, Jin;
Jinan, Gao;
Hu, Ping;
Kim, In Ho;
Liu, Hao-Yu;
Ennab, Wael;
Jha, Rajesh;
Cai, Demin

Publication type:

Article

Time-restricted feeding relieves high temperature-induced impairment on meat quality by activating the Nrf2/HO-1 pathway, modification of muscle fiber composition, and enriching the polyunsaturated fatty acids in pigs.

Published in:

Stress Biology, 2024, v. 4, n. 1, p. 1, doi. 10.1007/s44154-024-00182-w

By:

Li, Zhaojian;
Wang, Yiting;
Yuan, Peng;
Zhu, Yanli;
Hu, Ping;
Song, Tongxing;
Liu, Rui;
Liu, Hao-Yu;
Cai, Demin

Publication type:

Article

Alternatives to antibiotics in pig production: looking through the lens of immunophysiology.

Published in:

Stress Biology, 2024, v. 4, n. 1, p. 1, doi. 10.1007/s44154-023-00134-w

By:

Liu, Hao-Yu;
Zhu, Chuyang;
Zhu, Miaonan;
Yuan, Long;
Li, Shicheng;
Gu, Fang;
Hu, Ping;
Chen, Shihao;
Cai, Demin

Publication type:

Article

Malic enzyme 3 mediated the effects of malic acid on intestinal redox status and feed efficiency in broilers.

Published in:

Journal of Animal Science & Biotechnology, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s40104-025-01163-3

By:

Jiang, Hongfeng;
Li, Genghui;
Yang, Xue;
Feng, Xiaohua;
Li, Penglin;
Yang, Huisi;
Cai, Demin;
Jiang, Qingyan;
Shu, Gang

Publication type:

Article

Malic enzyme 3 mediated the effects of malic acid on intestinal redox status and feed efficiency in broilers.

Published in:

Journal of Animal Science & Biotechnology, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s40104-025-01163-3

By:

Jiang, Hongfeng;
Li, Genghui;
Yang, Xue;
Feng, Xiaohua;
Li, Penglin;
Yang, Huisi;
Cai, Demin;
Jiang, Qingyan;
Shu, Gang

Publication type:

Article

Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets.

Published in:

Journal of Animal Science & Biotechnology, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s40104-022-00793-1

By:

Zong, Qiufang;
Qu, Huan;
Zhao, Yahui;
Liu, Haoyu;
Wu, Shenglong;
Wang, Shuai;
Bao, Wenbin;
Cai, Demin

Publication type:

Article

Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin modification in porcine liver organoids.

Published in:

Journal of Animal Science & Biotechnology, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s40104-020-00511-9

By:

Zhang, Kexin;
Li, Hao;
Xin, Zimeng;
Li, Yanwei;
Wang, Xiaolong;
Hu, Yun;
Liu, Haoyu;
Cai, Demin

Publication type:

Article

Intravenous injection of microvesicle-delivery miR-130b alleviates high-fat diet-induced obesity in C57BL/6 mice through translational repression of PPAR-γ.

Published in:

Journal of Biomedical Science, 2015, v. 22, p. 1, doi. 10.1186/s12929-015-0193-4

By:

Shifeng Pan;
Xiaojing Yang;
Yimin Jia;
Yue Li;
Rirong Chen;
Min Wang;
Demin Cai;
Ruqian Zhao

Publication type:

Article

Lithocholic acid attenuates DON-induced inflammatory responses via epigenetic regulation of DUSP5 and TRAF5 in porcine intestinal epithelial cells.

Published in:

Frontiers in Veterinary Science, 2025, p. 1, doi. 10.3389/fvets.2025.1493496

By:

Wang, Shiqi;
Peng, Xiaoxu;
Zhu, Qi;
Lu, Sichen;
Hu, Ping;
Kim, In Ho;
Liu, Hao-Yu;
Ennab, Wael;
Muniyappan, Madesh;
Cai, Demin

Publication type:

Article

Transcriptome analysis provides new insights into the response of canine intestinal epithelial cells treated by sulforaphane: a natural product of cruciferous origin.

Published in:

Frontiers in Veterinary Science, 2024, p. 1, doi. 10.3389/fvets.2024.1460500

By:

Kaiqi Li;
Jin Yan;
Shiqi Wang;
Chuyang Zhu;
Qi Zhu;
Sichen Lu;
Ping Hu;
Dessie, Tadelle;
In Ho Kim;
Ahmed, Abdelkareem A.;
Hao-Yu Liu;
Ennab, Wael;
Demin Cai

Publication type:

Article

Nuclear Receptor PPARα as a Therapeutic Target in Diseases Associated with Lipid Metabolism Disorders.

Published in:

Nutrients, 2023, v. 15, n. 22, p. 4772, doi. 10.3390/nu15224772

By:

Hu, Ping;
Li, Kaiqi;
Peng, Xiaoxu;
Kan, Yufei;
Li, Hao;
Zhu, Yanli;
Wang, Ziyu;
Li, Zhaojian;
Liu, Hao-Yu;
Cai, Demin

Publication type:

Article

Orphan Nuclear Receptor RORγ Modulates the Genome-Wide Binding of the Cholesterol Metabolic Genes during Mycotoxin-Induced Liver Injury.

Published in:

Nutrients, 2021, v. 13, n. 8, p. 2539, doi. 10.3390/nu13082539

By:

Li, Kaiqi;
Li, Hao;
Zhang, Kexin;
Zhang, Jinying;
Hu, Ping;
Li, Yanwei;
Gu, Haotian;
Liu, Hao-Yu;
Yang, Zhangping;
Cai, Demin

Publication type:

Article

Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition.

Published in:

Nutrients, 2019, v. 11, n. 6, p. 1350, doi. 10.3390/nu11061350

By:

Liu, Hao-Yu;
Walden, Tomas B.;
Cai, Demin;
Ahl, David;
Bertilsson, Stefan;
Phillipson, Mia;
Nyman, Margareta;
Holm, Lena

Publication type:

Article

Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.

Published in:

Nutrients, 2016, v. 8, n. 10, p. 646, doi. 10.3390/nu8100646

By:

Demin Cai;
Mengjie Yuan;
Haoyu Liu;
Shifeng Pan;
Wenqiang Ma;
Jian Hong;
Ruqian Zhao

Publication type:

Article

Targeted inhibition of PPARα ameliorates CLA‐induced hypercholesterolemia via hepatic cholesterol biosynthesis reprogramming.

Published in:

Liver International, 2022, v. 42, n. 6, p. 1449, doi. 10.1111/liv.15199

By:

Liu, Hao‐Yu;
Hu, Ping;
Li, Yanwei;
Sun, Ming‐An;
Qu, Huan;
Zong, Qiufang;
Gu, Haotian;
Chen, Xiaobo;
Bao, Wenbin;
Cai, Demin

Publication type:

Article

The Metabolic Pathway of Bile Secretion Is Vulnerable to Salmonella enterica Exposure in Porcine Intestinal Epithelial Cells.

Published in:

Animals (2076-2615), 2024, v. 14, n. 5, p. 789, doi. 10.3390/ani14050789

By:

Cai, Jiajia;
Chen, Xiaolei;
Xu, Chao;
Zhu, Xiaoyang;
Wang, Haifei;
Wu, Shenglong;
Cai, Demin;
Fan, Hairui

Publication type:

Article

Correction: Jin et al. Effects of Zinc Source and Level on the Intestinal Immunity of Xueshan Chickens under Heat Stress. Animals 2023, 13 , 3025.

Published in:

2023

By:

Jin, Jian;
Xue, Mengxiao;
Tang, Yuchen;
Zhang, Liangliang;
Hu, Ping;
Hu, Yun;
Cai, Demin;
Luo, Xugang;
Sun, Ming-an

Publication type:

Correction Notice

Effects of Zinc Source and Level on the Intestinal Immunity of Xueshan Chickens under Heat Stress.

Published in:

Animals (2076-2615), 2023, v. 13, n. 19, p. 3025, doi. 10.3390/ani13193025

By:

Jin, Jian;
Xue, Mengxiao;
Tang, Yuchen;
Zhang, Liangliang;
Hu, Ping;
Hu, Yun;
Cai, Demin;
Luo, Xugang;
Sun, Ming-an

Publication type:

Article

Hypermethylation of Sp1 Binding Site Suppresses Hypothalamic POMC in Neonates and May Contribute to Metabolic Disorders in Adults: Impact of Maternal Dietary CLAs.

Published in:

Diabetes, 2014, v. 63, n. 5, p. 1475, doi. 10.2337/db13-1221

By:

Xiaomei Zhang;
Ran Yang;
Yan Jia;
Demin Cai;
Bo Zhou;
Xiaoli Qu;
Huihua Han;
Liang Xu;
Linfeng Wang;
Yanan Yao;
Guoqing Yang

Publication type:

Article

Co‐option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA‐induced hepatic steatosis.

Published in:

Journal of Cellular Physiology, 2021, v. 236, n. 6, p. 4387, doi. 10.1002/jcp.30157

By:

Cai, Demin;
Li, Yanwei;
Zhang, Kexin;
Zhou, Bo;
Guo, Feilong;
Holm, Lena;
Liu, Hao‐Yu

Publication type:

Article

Natural products for Gut-X axis: pharmacology, toxicology and microbiology in mycotoxin-caused diseases.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1419844

By:

Kaiqi Li;
Shiqi Wang;
Wuyi Qu;
Ahmed, Abdelkareem A.;
Enneb, Wael;
Obeidat, Mohammad Diya';
Hao-Yu Liu;
Dessie, Tadelle;
In Ho Kim;
Adam, Saber Y.;
Cai, Demin

Publication type:

Article

In Ovo Injection of Betaine Affects Hepatic Cholesterol Metabolism through Epigenetic Gene Regulation in Newly Hatched Chicks.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122643

By:

Hu, Yun;
Sun, Qinwei;
Li, Xiaoliang;
Wang, Min;
Cai, Demin;
Li, Xi;
Zhao, Ruqian

Publication type:

Article

Betaine Supplementation in Maternal Diet Modulates the Epigenetic Regulation of Hepatic Gluconeogenic Genes in Neonatal Piglets.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105504

By:

Cai, Demin;
Jia, Yimin;
Song, Haogang;
Sui, Shiyan;
Lu, Jingyu;
Jiang, Zheng;
Zhao, Ruqian

Publication type:

Article

Fungi in the Gut Microbiota: Interactions, Homeostasis, and Host Physiology.

Published in:

Microorganisms, 2025, v. 13, n. 1, p. 70, doi. 10.3390/microorganisms13010070

By:

Liu, Hao-Yu;
Li, Shicheng;
Ogamune, Kennedy Jerry;
Ahmed, Abdelkareem A.;
Kim, In Ho;
Zhang, Yunzeng;
Cai, Demin

Publication type:

Article

A master regulator of cholesterol biosynthesis constitutes a therapeutic liability of triple negative breast cancer.

Published in:

2020

By:

Cai, Demin;
Zhang, Xiong;
Chen, Hong-Wu

Publication type:

Opinion

Butyrate stimulates adipose lipolysis and mitochondrial oxidative phosphorylation through histone hyperacetylation-associated β<sub>3</sub>-adrenergic receptor activation in high-fat diet-induced obese mice.

Published in:

Experimental Physiology, 2017, v. 102, n. 2, p. 273, doi. 10.1113/EP086114

By:

Jia, Yimin;
Hong, Jian;
Li, Huifang;
Hu, Yun;
Jia, Longfei;
Cai, Demin;
Zhao, Ruqian

Publication type:

Article

In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.

Published in:

Scientific Reports, 2017, p. 40251, doi. 10.1038/srep40251

By:

Hu, Yun;
Sun, Qinwei;
Liu, Jie;
Jia, Yimin;
Cai, Demin;
Idriss, Abdulrahman A.;
Omer, Nagmeldin A.;
Zhao, Ruqian

Publication type:

Article

Desmosterol: A natural product derived from macroalgae modulates inflammatory response and oxidative stress pathways in intestinal epithelial cells.

Published in:

Frontiers in Immunology, 2023, v. 13, p. 01, doi. 10.3389/fimmu.2022.1101643

By:

Huan Qu;
Qiufang Zong;
Ping Hu;
Zhaojian Li;
Haifei Wang;
Shenglong Wu;
Hao-Yu Liu;
Wenbin Bao;
Demin Cai

Publication type:

Article

C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.881289

By:

Qu, Huan;
Zong, Qiufang;
Wang, Haifei;
Wu, Shenglong;
Cai, Demin;
Bao, Wenbin

Publication type:

Article

Epithelial Heat Shock Proteins Mediate the Protective Effects of Limosilactobacillus reuteri in Dextran Sulfate Sodium-Induced Colitis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.865982

By:

Liu, Hao-Yu;
Gu, Fang;
Zhu, Cuipeng;
Yuan, Long;
Zhu, Chuyang;
Zhu, Miaonan;
Yao, Jiacheng;
Hu, Ping;
Zhang, Yunzeng;
Dicksved, Johan;
Bao, Wenbin;
Cai, Demin

Publication type:

Article

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12529-3

By:

Cai, Demin;
Wang, Junjian;
Gao, Bei;
Li, Jin;
Wu, Feng;
Zou, June X.;
Xu, Jianzhen;
Jiang, Yuqian;
Zou, Hongye;
Huang, Zenghong;
Borowsky, Alexander D.;
Bold, Richard J.;
Lara, Primo N.;
Li, Jian Jian;
Chen, Xinbin;
Lam, Kit S.;
To, Ka-Fai;
Kung, Hsing-Jien;
Fiehn, Oliver;
Zhao, Ruqian

Publication type:

Article