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Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities.
- Published in:
- ChemMedChem, 2024, v. 19, n. 9, p. 1, doi. 10.1002/cmdc.202300667
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- Publication type:
- Article
Design, Synthesis, and Evaluation of An Anti‐trypanosomal [1,2,4]Triazolo[1,5‐a]pyrimidine Probe for Photoaffinity Labeling Studies.
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- ChemMedChem, 2024, v. 19, n. 8, p. 1, doi. 10.1002/cmdc.202300656
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- Publication type:
- Article
Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines.
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- Parasitology Research, 2023, v. 122, n. 12, p. 2751, doi. 10.1007/s00436-023-07993-2
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- Publication type:
- Article
Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolo[1,5‐a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis**.
- Published in:
- ChemMedChem, 2023, v. 18, n. 20, p. 1, doi. 10.1002/cmdc.202300193
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- Publication type:
- Article
Front Cover: Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolo[1,5‐a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis (ChemMedChem 20/2023).
- Published in:
- ChemMedChem, 2023, v. 18, n. 20, p. 1, doi. 10.1002/cmdc.202300558
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- Publication type:
- Article
Seaweeds and Corals from the Brazilian Coast: Review on Biotechnological Potential and Environmental Aspects.
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- Molecules, 2023, v. 28, n. 11, p. 4285, doi. 10.3390/molecules28114285
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- Publication type:
- Article
A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani.
- Published in:
- Pathogens, 2022, v. 11, n. 12, p. 1424, doi. 10.3390/pathogens11121424
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- Publication type:
- Article
Biomechanical interactions of Schistosoma mansoni eggs with vascular endothelial cells facilitate egg extravasation.
- Published in:
- PLoS Pathogens, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1010309
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- Publication type:
- Article
Brazilian green propolis reduces worm burden and hepatic granuloma formation in a Schistosoma mansoni experimental murine model.
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- Parasitology Research, 2022, v. 121, n. 2, p. 775, doi. 10.1007/s00436-021-07408-0
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- Publication type:
- Article
Antiparasitic Properties of Propolis Extracts and Their Compounds.
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- Chemistry & Biodiversity, 2021, v. 18, n. 9, p. 1, doi. 10.1002/cbdv.202100310
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- Publication type:
- Article
Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 5, p. 400, doi. 10.3390/ph14050400
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- Publication type:
- Article
Understanding the key processes of excellence as a prerequisite to establishing academic centres of excellence in Africa.
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- BMC Medical Education, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12909-020-02471-0
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- Publication type:
- Article
Correction to: Understanding the key processes of excellence as a prerequisite to establishing academic centres of excellence in Africa.
- Published in:
- 2021
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- Publication type:
- Correction Notice
A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discovery.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01402-5
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- Publication type:
- Article
Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.
- Published in:
- 2020
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- Publication type:
- journal article
Uncovering Biological Application of Brazilian Green Propolis: A Phenotypic Screening against Schistosoma mansoni.
- Published in:
- Chemistry & Biodiversity, 2020, v. 17, n. 9, p. 1, doi. 10.1002/cbdv.202000277
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- Publication type:
- Article
Author Correction: Caenorhabditiselegans is a useful model for anthelmintic discovery.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity.
- Published in:
- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 3, p. 1, doi. 10.1371/journal.pntd.0008150
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- Publication type:
- Article
Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fcimb.2020.00066
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- Publication type:
- Article
Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59460-y
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- Publication type:
- Article
Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty.
- Published in:
- Pharmaceuticals (14248247), 2020, v. 13, n. 2, p. 25, doi. 10.3390/ph13020025
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- Publication type:
- Article
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery.
- Published in:
- Parasites & Vectors, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13071-019-3747-6
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- Publication type:
- Article
Molecular characterization and functional analysis of the Schistosoma mekongi Ca<sup>2+</sup>-dependent cysteine protease (calpain)
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- Parasites & Vectors, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13071-019-3639-9
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- Publication type:
- Article
Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics.
- Published in:
- PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0217019
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- Publication type:
- Article
Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. N.PAG, doi. 10.3389/fcimb.2019.00180
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- Publication type:
- Article
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.
- Published in:
- PLoS Neglected Tropical Diseases, 2019, v. 13, n. 2, p. 1, doi. 10.1371/journal.pntd.0007129
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- Publication type:
- Article
High Throughput and Computational Repurposing for Neglected Diseases.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2558-3
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- Publication type:
- Article
A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response.
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- PLoS Neglected Tropical Diseases, 2019, v. 13, n. 1, p. 1, doi. 10.1371/journal.pntd.0007070
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- Publication type:
- Article
Brain‐Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis.
- Published in:
- ChemMedChem, 2018, v. 13, n. 17, p. 1751, doi. 10.1002/cmdc.201800404
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- Publication type:
- Article
Cysteine proteases as digestive enzymes in parasitic helminths.
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- PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005840
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- Publication type:
- Article
Cysteine proteases during larval migration and development of helminths in their final host.
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- PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005919
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- Publication type:
- Article
Effect of Phenotypic Screening of Extracts and Fractions of Erythrophleum ivorense Leaf and Stem Bark on Immature and Adult Stages of Schistosoma mansoni.
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- Journal of Parasitology Research, 2018, p. 1, doi. 10.1155/2018/9431467
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- Publication type:
- Article
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.
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- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 4, p. 1, doi. 10.1371/journal.pntd.0006446
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- Publication type:
- Article
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005680
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- Publication type:
- Article
Targeting proteasomes in infectious organisms to combat disease.
- Published in:
- FEBS Journal, 2017, v. 284, n. 10, p. 1503, doi. 10.1111/febs.14029
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- Publication type:
- Article
Sex-Biased Transcriptome of Schistosoma mansoni: Host-Parasite Interaction, Genetic Determinants and Epigenetic Regulators Are Associated with Sexual Differentiation.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 9, p. 1, doi. 10.1371/journal.pntd.0004930
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- Publication type:
- Article
Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo.
- Published in:
- Pharmaceuticals (14248247), 2016, v. 9, n. 3, p. 39, doi. 10.3390/ph9030039
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- Publication type:
- Article
Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.
- Published in:
- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 1, p. 1, doi. 10.1371/journal.pntd.0004356
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- Publication type:
- Article
Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 1, p. 1, doi. 10.1371/journal.pntd.0004357
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni.
- Published in:
- Molecules, 2015, v. 20, n. 6, p. 10873, doi. 10.3390/molecules200610873
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- Publication type:
- Article
Caenorhabditis elegans is a useful model for anthelmintic discovery.
- Published in:
- Nature Communications, 2015, v. 6, n. 6, p. 7485, doi. 10.1038/ncomms8485
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
The QDREC web server: determining dose--response characteristics of complex macroparasites in phenotypic drug screens.
- Published in:
- 2015
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- Publication type:
- Product Review
Anthelmintic Drug Discovery: Into the Future.
- Published in:
- Journal of Parasitology, 2015, v. 101, n. 2, p. 125, doi. 10.1645/14-703.1
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- Publication type:
- Article
Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 6, p. 1, doi. 10.1371/journal.pntd.0002949
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- Publication type:
- Article
Regulation of <i>Schistosoma mansoni</i> Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 6, p. 1, doi. 10.1371/journal.pntd.0002949
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- Publication type:
- Article
Trypsin- and Chymotrypsin-Like Serine Proteases in Schistosoma mansoni – 'The Undiscovered Country'.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 3, p. 1, doi. 10.1371/journal.pntd.0002766
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- Publication type:
- Article
Trypsin- and Chymotrypsin-Like Serine Proteases in <i>Schistosoma mansoni</i> – ‘The Undiscovered Country’.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 3, p. 1, doi. 10.1371/journal.pntd.0002766
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- Publication type:
- Article
Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087594
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- Publication type:
- Article