Works by CHOWDHURY, Rasheduzzaman

Results: 38

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.
Published in:
Angewandte Chemie, 2021, v. 133, n. 26, p. 14778, doi. 10.1002/ange.202103711
By:
- Brasnett, Amelia;
- Pfeffer, Inga;
- Brewitz, Lennart;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
A human protein hydroxylase that accepts D-residues.
Published in:
Communications Chemistry, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42004-020-0290-5
By:
- Choi, Hwanho;
- Hardy, Adam P.;
- Leissing, Thomas M.;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Ge, Wei;
- Markoulides, Marios;
- Scotti, John S.;
- Gerken, Philip A.;
- Thorbjornsrud, Helen;
- Kang, Dahye;
- Hong, Sungwoo;
- Lee, Joongoo;
- McDonough, Michael A.;
- Park, Hwangseo;
- Schofield, Christopher J.
Publication type:
Article
Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.
Published in:
ChemBioChem, 2018, v. 19, n. 21, p. 2262, doi. 10.1002/cbic.201800246
By:
- Abboud, Martine I.;
- Chowdhury, Rasheduzzaman;
- Leung, Ivanhoe K. H.;
- Lippl, Kerstin;
- Loenarz, Christoph;
- Claridge, Timothy D. W.;
- Schofield, Christopher J.
Publication type:
Article
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.
Published in:
Angewandte Chemie International Edition, 2012, v. 51, n. 27, p. 6672, doi. 10.1002/anie.201202000
By:
- Demetriades, Marina;
- Leung, Ivanhoe K. H.;
- Chowdhury, Rasheduzzaman;
- Chan, Mun Chiang;
- McDonough, Michael A.;
- Yeoh, Kar Kheng;
- Tian, Ya-Min;
- Claridge, Timothy D. W.;
- Ratcliffe, Peter J.;
- Woon, Esther C. Y.;
- Schofield, Christopher J.
Publication type:
Article
Evidence for a Stereoelectronic Effect in Human Oxygen Sensing.
Published in:
Angewandte Chemie International Edition, 2009, v. 48, n. 10, p. 1784, doi. 10.1002/anie.200805427
By:
- Loenarz, Christoph;
- Mecinović, Jasmin;
- Chowdhury, Rasheduzzaman;
- McNeill, Luke A.;
- Flashman, Emily;
- Schofield, Christopher J.
Publication type:
Article
Mechanistic and structural studies of KDM‐catalysed demethylation of histone 1 isotype 4 at lysine 26.
Published in:
FEBS Letters, 2018, v. 592, n. 19, p. 3264, doi. 10.1002/1873-3468.13231
By:
- Walport, Louise J.;
- Hopkinson, Richard J.;
- Chowdhury, Rasheduzzaman;
- Zhang, Yijia;
- Bonnici, Joanna;
- Schiller, Rachel;
- Kawamura, Akane;
- Schofield, Christopher J.
Publication type:
Article
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Published in:
Nature, 2014, v. 510, n. 7505, p. 422, doi. 10.1038/nature13263
By:
- Chowdhury, Rasheduzzaman;
- Sekirnik, Rok;
- Brissett, Nigel C.;
- Krojer, Tobias;
- Ho, Chia-hua;
- Ng, Stanley S.;
- Clifton, Ian J.;
- Ge, Wei;
- Kershaw, Nadia J.;
- Fox, Gavin C.;
- Muniz, Joao R. C.;
- Vollmar, Melanie;
- Phillips, Claire;
- Pilka, Ewa S.;
- Kavanagh, Kathryn L.;
- von Delft, Frank;
- Oppermann, Udo;
- McDonough, Michael A.;
- Doherty, Aidan J.;
- Schofield, Christopher J.
Publication type:
Article
Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.884399
By:
- Zhou, Yu;
- Li, Xin;
- Shen, Ru;
- Wang, Xiangzhu;
- Zhang, Fan;
- Liu, Suxing;
- Li, Di;
- Liu, Jian;
- Li, Puhui;
- Yan, Yinfa;
- Dong, Ping;
- Zhang, Zhigao;
- Wu, Heping;
- Zhuang, Linghang;
- Chowdhury, Rasheduzzaman;
- Miller, Matthew;
- Issa, Mena;
- Mao, Yuchang;
- Chen, Hongli;
- Feng, Jun
Publication type:
Article
The oxygenase Jmjd6 - a case study in conflicting assignments.
Published in:
2015
By:
- Böttger, Angelika;
- Islam, Md. Saiful;
- Chowdhury, Rasheduzzaman;
- Schofield, J.;
- Wolf, Alexander
Publication type:
Case Study
Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen.
Published in:
Biochemical Journal, 2014, v. 463, n. 3, p. 363, doi. 10.1042/BJ20140779
By:
- TARHONSKAYA, Hanna;
- CHOWDHURY, Rasheduzzaman;
- LEUNG, Ivanhoe K. H.;
- LOIK, Nikita D.;
- MCCULLAGH, James S. O.;
- CLARIDGE, Timothy D. W.;
- SCHOFIELD, Christopher J.;
- FLASHMAN, Emily
Publication type:
Article
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Published in:
Nature Communications, 2017, v. 8, n. 4, p. 14773, doi. 10.1038/ncomms14773
By:
- Kawamura, Akane;
- Münzel, Martin;
- Kojima, Tatsuya;
- Yapp, Clarence;
- Bhushan, Bhaskar;
- Goto, Yuki;
- Tumber, Anthony;
- Katoh, Takayuki;
- King, Oliver N. F.;
- Passioura, Toby;
- Walport, Louise J.;
- Hatch, Stephanie B.;
- Madden, Sarah;
- Müller, Susanne;
- Brennan, Paul E.;
- Chowdhury, Rasheduzzaman;
- Hopkinson, Richard J.;
- Suga, Hiroaki;
- Schofield, Christopher J.
Publication type:
Article
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Published in:
Nature Communications, 2016, v. 7, n. 8, p. 12673, doi. 10.1038/ncomms12673
By:
- Chowdhury, Rasheduzzaman;
- Leung, Ivanhoe K. H.;
- Tian, Ya-Min;
- Abboud, Martine I.;
- Ge, Wei;
- Domene, Carmen;
- Cantrelle, François-Xavier;
- Landrieu, Isabelle;
- Hardy, Adam P.;
- Pugh, Christopher W.;
- Ratcliffe, Peter J.;
- Claridge, Timothy D. W.;
- Schofield, Christopher J.
Publication type:
Article
Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.
Published in:
Nature Communications, 2016, v. 7, n. 6, p. 11974, doi. 10.1038/ncomms11974
By:
- Walport, Louise J.;
- Hopkinson, Richard J.;
- Chowdhury, Rasheduzzaman;
- Schiller, Rachel;
- Ge, Wei;
- Kawamura, Akane;
- Schofield, Christopher J.
Publication type:
Article
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132004
By:
- Chan, Mun Chiang;
- Atasoylu, Onur;
- Hodson, Emma;
- Tumber, Anthony;
- Leung, Ivanhoe K. H.;
- Chowdhury, Rasheduzzaman;
- Gómez-Pérez, Verónica;
- Demetriades, Marina;
- Rydzik, Anna M.;
- Holt-Martyn, James;
- Tian, Ya-Min;
- Bishop, Tammie;
- Claridge, Timothy D. W.;
- Kawamura, Akane;
- Pugh, Christopher W.;
- Ratcliffe, Peter J.;
- Schofield, Christopher J.
Publication type:
Article
Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.
Published in:
FEBS Journal, 2011, v. 278, n. 7, p. 1086, doi. 10.1111/j.1742-4658.2011.08022.x
By:
- Yang, Ming;
- Chowdhury, Rasheduzzaman;
- Ge, Wei;
- Hamed, Refaat B.;
- McDonough, Michael A.;
- Claridge, Timothy D. W.;
- Kessler, Benedikt M.;
- Cockman, Matthew E.;
- Ratcliffe, Peter J.;
- Schofield, Christopher J.
Publication type:
Article
SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12449-1
By:
- Song, Chunying;
- Liu, Dong;
- Liu, Suxing;
- Li, Di;
- Horecny, Ivana;
- Zhang, Xinzhu;
- Li, Puhui;
- Chen, Lei;
- Miller, Matthew;
- Chowdhury, Rasheduzzaman;
- Issa, Mena;
- Shen, Ru;
- Yan, Yinfa;
- Zhang, Fengqi;
- Zhang, Lei;
- Zhang, Limin;
- Bai, Chang;
- Feng, Jun;
- Zhuang, Linghang;
- Zhang, Rumin
Publication type:
Article
Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10028-y
By:
- Chowdhury, Rasheduzzaman;
- Abboud, Martine I.;
- Wiley, James;
- Tumber, Anthony;
- Markolovic, Suzana;
- Schofield, Christopher J.
Publication type:
Article
Publisher Correction: JMJD5 is a human arginyl C-3 hydroxylase.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04196-7
By:
- Wilkins, Sarah E.;
- Islam, Md. Saiful;
- Gannon, Joan M.;
- Markolovic, Suzana;
- Hopkinson, Richard J.;
- Wei Ge;
- Schofield, Christopher J.;
- Chowdhury, Rasheduzzaman
Publication type:
Article
JMJD5 is a human arginyl C-3 hydroxylase.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03410-w
By:
- Wilkins, Sarah E.;
- Islam, Md. Saiful;
- Gannon, Joan M.;
- Markolovic, Suzana;
- Hopkinson, Richard J.;
- Wei Ge;
- Schofield, Christopher J.;
- Chowdhury, Rasheduzzaman
Publication type:
Article
Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 26, p. 14657, doi. 10.1002/anie.202103711
By:
- Brasnett, Amelia;
- Pfeffer, Inga;
- Brewitz, Lennart;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Inhibition of JMJD6 by 2‐Oxoglutarate Mimics.
Published in:
ChemMedChem, 2022, v. 17, n. 1, p. 1, doi. 10.1002/cmdc.202100398
By:
- Islam, Md. Sailful;
- Thinnes, Cyrille C.;
- Holt‐Martyn, James P.;
- Chowdhury, Rasheduzzaman;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Published in:
ChemMedChem, 2021, v. 16, n. 13, p. 2082, doi. 10.1002/cmdc.202100133
By:
- Figg, William D.;
- McDonough, Michael A.;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Zhang, Zhihong;
- Holt‐Martyn, James P.;
- Krajnc, Alen;
- Schofield, Christopher J.
Publication type:
Article
Structure‐Activity Relationship and Crystallographic Studies on 4‐Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors.
Published in:
ChemMedChem, 2020, v. 15, n. 3, p. 270, doi. 10.1002/cmdc.201900557
By:
- Holt‐Martyn, James P.;
- Chowdhury, Rasheduzzaman;
- Tumber, Anthony;
- Yeh, Tzu‐Lan;
- Abboud, Martine I.;
- Lippl, Kerstin;
- Lohans, Christopher T.;
- Langley, Gareth W.;
- Figg, William;
- McDonough, Michael A.;
- Pugh, Christopher W.;
- Ratcliffe, Peter J.;
- Schofield, Christopher J.
Publication type:
Article
ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site.
Published in:
ChemMedChem, 2008, v. 3, n. 4, p. 569, doi. 10.1002/cmdc.200700233
By:
- Mecinović, Jasmin;
- Chowdhury, Rasheduzzaman;
- Liénard, Benoît M. R.;
- Flashman, Emily;
- Buck, Matthew R. G.;
- Oldham, Neil J.;
- Schofield, Christopher J.
Publication type:
Article
Cover Picture: ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site (ChemMedChem 4/2008).
Published in:
ChemMedChem, 2008, v. 3, n. 4, p. 509, doi. 10.1002/cmdc.200890014
By:
- Mecinović, Jasmin;
- Chowdhury, Rasheduzzaman;
- Liénard, Benoît M. R.;
- Flashman, Emily;
- Buck, Matthew R. G.;
- Oldham, Neil J.;
- Schofield, Christopher J.
Publication type:
Article
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
Published in:
EMBO Reports, 2011, v. 12, n. 5, p. 463, doi. 10.1038/embor.2011.43
By:
- Chowdhury, Rasheduzzaman;
- Yeoh, Kar Kheng;
- Tian, Ya-Min;
- Hillringhaus, Lars;
- Bagg, Eleanor A;
- Rose, Nathan R;
- Leung, Ivanhoe K H;
- Li, Xuan S;
- Woon, Esther C Y;
- Yang, Ming;
- McDonough, Michael A;
- King, Oliver N;
- Clifton, Ian J;
- Klose, Robert J;
- Claridge, Timothy D W;
- Ratcliffe, Peter J;
- Schofield, Christopher J;
- Kawamura, Akane
Publication type:
Article
Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.
Published in:
Proteins, 2010, v. 78, n. 6, p. 1398, doi. 10.1002/prot.22653
By:
- Iqbal, Aman;
- Arunlanantham, Haren;
- Brown, Tom;
- Chowdhury, Rasheduzzaman;
- Clifton, Ian J.;
- Kershaw, Nadia J.;
- Hewitson, Kirsty S.;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor.
Published in:
Angewandte Chemie, 2013, v. 125, n. 6, p. 1744, doi. 10.1002/ange.201208046
By:
- Yang, Ming;
- Hardy, Adam P.;
- Chowdhury, Rasheduzzaman;
- Loik, Nikita D.;
- Scotti, John S.;
- McCullagh, James S. O.;
- Claridge, Timothy D. W.;
- McDonough, Michael A.;
- Ge, Wei;
- Schofield, Christopher J.
Publication type:
Article
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.
Published in:
Angewandte Chemie, 2012, v. 124, n. 27, p. 6776, doi. 10.1002/ange.201202000
By:
- Demetriades, Marina;
- Leung, Ivanhoe K. H.;
- Chowdhury, Rasheduzzaman;
- Chan, Mun Chiang;
- McDonough, Michael A.;
- Yeoh, Kar Kheng;
- Tian, Ya-Min;
- Claridge, Timothy D. W.;
- Ratcliffe, Peter J.;
- Woon, Esther C. Y.;
- Schofield, Christopher J.
Publication type:
Article
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.
Published in:
Epigenetics, 2014, v. 9, n. 12, p. 1596, doi. 10.4161/15592294.2014.983381
By:
- Williams, Sophie T;
- Walport, Louise J;
- Hopkinson, Richard J;
- Madden, Sarah K;
- Chowdhury, Rasheduzzaman;
- Schofield, Christopher J;
- Kawamura, Akane
Publication type:
Article
Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-76307-8
By:
- Chowdhury, Rasheduzzaman;
- Abboud, Martine I.;
- McAllister, Tom E.;
- Banerji, Biswadip;
- Bhushan, Bhaskar;
- Sorensen, John L.;
- Kawamura, Akane;
- Schofield, Christopher J.
Publication type:
Article
Bioactivity of Extractives from Stachytarpheta urticaefolia.
Published in:
Pharmaceutical Biology, 2004, v. 42, n. 3, p. 262, doi. 10.1080/13880200490514203
By:
- Chowdhury, Rasheduzzaman;
- Rashid, Mamun Ur;
- Khan, Omar Faruk;
- Hasan, Choudhury
Publication type:
Article
Bioactivity from Toona ciliata Stem Bark.
Published in:
Pharmaceutical Biology, 2003, v. 41, n. 4, p. 281, doi. 10.1076/phbi.41.4.281.15662
By:
- Chowdhury, Rasheduzzaman;
- Hasan, Choudhury M.;
- Rashid, Mohammad A.
Publication type:
Article
Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.
Published in:
Proteins, 2023, v. 91, n. 11, p. 1510, doi. 10.1002/prot.26541
By:
- Figg, William D.;
- Fiorini, Giorgia;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-24154-0
By:
- Islam, Md. Saiful;
- Markoulides, Marios;
- Chowdhury, Rasheduzzaman;
- Schofield, Christopher J.
Publication type:
Article
Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor.
Published in:
Angewandte Chemie International Edition, 2013, v. 52, n. 6, p. 1700, doi. 10.1002/anie.201208046
By:
- Yang, Ming;
- Hardy, Adam P.;
- Chowdhury, Rasheduzzaman;
- Loik, Nikita D.;
- Scotti, John S.;
- McCullagh, James S. O.;
- Claridge, Timothy D. W.;
- McDonough, Michael A.;
- Ge, Wei;
- Schofield, Christopher J.
Publication type:
Article
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 12, p. 960, doi. 10.1038/nchembio.1093
By:
- Ge, Wei;
- Wolf, Alexander;
- Feng, Tianshu;
- Ho, Chia-hua;
- Sekirnik, Rok;
- Zayer, Adam;
- Granatino, Nicolas;
- Cockman, Matthew E;
- Loenarz, Christoph;
- Loik, Nikita D;
- Hardy, Adam P;
- Claridge, Timothy D W;
- Hamed, Refaat B;
- Chowdhury, Rasheduzzaman;
- Gong, Lingzhi;
- Robinson, Carol V;
- Trudgian, David C;
- Jiang, Miao;
- Mackeen, Mukram M;
- Mccullagh, James S
Publication type:
Article
A Convenient Synthesis of New Annelated Pyrimidines and Their Biological Importance.
Published in:
Journal of Heterocyclic Chemistry, 2014, v. 51, p. E216, doi. 10.1002/jhet.1891
By:
- Wahab Khan, M.;
- Uddin, Mohammed Kabir;
- Ali, Morshed;
- Rahman, Mohammad S.;
- Rashid, Mohammad Abdur;
- Chowdhury, Rasheduzzaman
Publication type:
Article