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Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 7, p. 3047, doi. 10.1172/JCI73469
By:
- Henderson, Ashley G.;
- Ehre, Camille;
- Button, Brian;
- Abdullah, Lubna H.;
- Li-Heng Cai;
- Leigh, Margaret W.;
- DeMaria, Genevieve C.;
- Matsui, Hiro;
- Donaldson, Scott H.;
- Davis, C. William;
- Sheehan, John K.;
- Boucher, Richard C.;
- Kesimer, Mehmet
Publication type:
Article
Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia.
Published in:
Journal of Physiology, 2007, v. 580, n. 2, p. 577, doi. 10.1113/jphysiol.2006.126086
By:
- Button, Brian;
- Picher, Maryse;
- Boucher, Richard C.
Publication type:
Article
Airway Epithelial Nucleotide Release Contributes to Mucociliary Clearance.
Published in:
Life (2075-1729), 2021, v. 11, n. 5, p. 430, doi. 10.3390/life11050430
By:
- van Heusden, Catharina;
- Grubb, Barbara R.;
- Button, Brian;
- Lazarowski, Eduardo R.;
- Grygorczyk, Ryszard;
- Boudreault, Francis
Publication type:
Article
TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis.
Published in:
2020
By:
- Danahay, Henry;
- Lilley, Sarah;
- Fox, Roy;
- Charlton, Holly;
- Sabater, Juan;
- Button, Brian;
- McCarthy, Clive;
- Collingwood, Steve;
- Gosling, Martin;
- Danahay, Henry L;
- Collingwood, Stephen P
Publication type:
journal article
The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis.
Published in:
2015
By:
- Anderson, Wayne H;
- Coakley, Raymond D;
- Button, Brian;
- Henderson, Ashley G;
- Zeman, Kirby L;
- Alexis, Neil E;
- Peden, David B;
- Lazarowski, Eduardo R;
- Davis, C William;
- Bailey, Summer;
- Fuller, Fred;
- Almond, Martha;
- Qaqish, Bahjat;
- Bordonali, Elena;
- Rubinstein, Michael;
- Bennett, William D;
- Kesimer, Mehmet;
- Boucher, Richard C
Publication type:
journal article
The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 2, p. 182, doi. 10.1164/rccm.201412-2230oc
By:
- Anderson, Wayne H.;
- Coakley, Raymond D.;
- Button, Brian;
- Henderson, Ashley G.;
- Zeman, Kirby L.;
- Alexis, Neil E.;
- Peden, David B.;
- Lazarowski, Eduardo R.;
- Davis, C. William;
- Bailey, Summer;
- Fuller, Fred;
- Almond, Martha;
- Qaqish, Bahjat;
- Bordonali, Elena;
- Rubinstein, Michael;
- Bennett, William D.;
- Kesimer, Mehmet;
- Boucher, Richard C.
Publication type:
Article
IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis.
Published in:
2019
By:
- Gang Chen;
- Ling Sun;
- Takafumi Kato;
- Kenichi Okuda;
- Martino, Mary B.;
- Abzhanova, Aiman;
- Lin, Jennifer M.;
- Gilmore, Rodney C.;
- Batson, Bethany D.;
- O'Neal, Yvonne K.;
- Volmer, Allison S.;
- Hong Dang;
- Yangmei Deng;
- Randell, Scott H.;
- Button, Brian;
- Livraghi-Butrico, Alessandra;
- Kesimer, Mehmet;
- Ribeiro, Carla M. P.;
- O'Neal, Wanda K.;
- Boucher, Richard C.
Publication type:
journal article
CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium.
Published in:
PLoS Biology, 2009, v. 7, n. 7, p. 1, doi. 10.1371/journal.pbio.1000155
By:
- Liqun Zhang;
- Button, Brian;
- Gabriel, Sherif E.;
- Burkett, Susan;
- Yu Yan;
- Skiadopoulos, Mario H.;
- Yan Li Dang;
- Vogel, Leatrice N.;
- McKay, Tristan;
- Mengos, April;
- Boucher, Richard C.;
- Collins, Peter L.;
- Pickles, Raymond J.
Publication type:
Article
Airway surface liquid pH is not acidic in children with cystic fibrosis.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00532-5
By:
- Schultz, André;
- Puvvadi, Ramaa;
- Borisov, Sergey M.;
- Shaw, Nicole C.;
- Klimant, Ingo;
- Berry, Luke J.;
- Montgomery, Samuel T.;
- Thien Nguyen;
- Kreda, Silvia M.;
- Kicic, Anthony;
- Noble, Peter B.;
- Button, Brian;
- Stick, Stephen M.
Publication type:
Article
Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype.
Published in:
2016
By:
- Button, Brian;
- Anderson, Wayne H.;
- Boucher, Richard C.
Publication type:
journal article
Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33053-2
By:
- Rogers, Troy D.;
- Ostrowski, Lawrence E.;
- Livraghi-Butrico, Alessandra;
- Button, Brian;
- Grubb, Barbara R.
Publication type:
Article
Regional Differences in Mucociliary Clearance in the Upper and Lower Airways.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.842592
By:
- Rogers, Troy D.;
- Button, Brian;
- Kelada, Samir N. P.;
- Ostrowski, Lawrence E.;
- Livraghi-Butrico, Alessandra;
- Gutay, Mark I.;
- Esther Jr., Charles R.;
- Grubb, Barbara R.
Publication type:
Article
Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.
Published in:
Science Translational Medicine, 2023, v. 15, n. 699, p. 1, doi. 10.1126/scitranslmed.abo7728
By:
- Mikami, Yu;
- Grubb, Barbara R.;
- Rogers, Troy D.;
- Dang, Hong;
- Asakura, Takanori;
- Kota, Pradeep;
- Gilmore, Rodney C.;
- Okuda, Kenichi;
- Morton, Lisa C.;
- Sun, Ling;
- Chen, Gang;
- Wykoff, Jason A.;
- Ehre, Camille;
- Vilar, Juan;
- van Heusden, Catharina;
- Livraghi-Butrico, Alessandra;
- Gentzsch, Martina;
- Button, Brian;
- Stutts, M. Jackson;
- Randell, Scott H.
Publication type:
Article
Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways.
Published in:
Science Signaling, 2013, v. 6, n. 279, p. 1, doi. 10.1126/scisignal.2003755
By:
- Button, Brian;
- Okada, Seiko F.;
- Frederick, Charles Brandon;
- Thelin, William R.;
- Boucher, Richard C.
Publication type:
Article

Found: 14