Works by Butovsky, Oleg

Results: 57

Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57684-y

By:

McKinsey, Gabriel L.;
Santander, Nicolas;
Zhang, Xiaoming;
Kleemann, Kilian L.;
Tran, Lauren;
Katewa, Aditya;
Conant, Kaylynn;
Barraza, Matthew;
Waddell, Kian;
Lizama, Carlos O.;
La Russa, Marie;
Koo, Ji Hyun;
Lee, Hyunji;
Mukherjee, Dibyanti;
Paidassi, Helena;
Anton, E. S.;
Atabai, Kamran;
Sheppard, Dean;
Butovsky, Oleg;
Arnold, Thomas D.

Publication type:

Article

Regulatory T Cells and Their Derived Cytokine, Interleukin-35, Reduce Pain in Experimental Autoimmune Encephalomyelitis.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 12, p. 2326, doi. 10.1523/JNEUROSCI.1815-18.2019

By:

Duffy, Samuel S.;
Keating, Brooke A.;
Perera, Chamini J.;
Lees, Justin G.;
Tonkin, Ryan S.;
Makker, Preet G. S.;
Carrive, Pascal;
Butovsky, Oleg;
Moalem-Taylor, Gila

Publication type:

Article

Sex‐dependent APOE4 neutrophil‐microglia interactions drive cognitive impairment in Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.087776

By:

Butovsky, Oleg

Publication type:

Article

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25115-3

By:

Moreira, Thais G.;
Mangani, Davide;
Cox, Laura M.;
Leibowitz, Jeffrey;
Lobo, Eduardo. L. C.;
Oliveira, Mariana A.;
Gauthier, Christian D.;
Nakagaki, Brenda N.;
Willocq, Valerie;
Song, Anya;
Guo, Lydia;
Lima, David C. A.;
Murugaiyan, Gopal;
Butovsky, Oleg;
Gabriely, Galina;
Anderson, Ana C.;
Rezende, Rafael M.;
Faria, Ana Maria C.;
Weiner, Howard L.

Publication type:

Article

Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts.

Published in:

Brain Pathology, 2018, v. 28, n. 6, p. 791, doi. 10.1111/bpa.12583

By:

Zrzavy, Tobias;
Machado‐Santos, Joana;
Christine, Sheren;
Baumgartner, Christoph;
Weiner, Howard L.;
Butovsky, Oleg;
Lassmann, Hans

Publication type:

Article

Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time.

Published in:

Brain Pathology, 2017, v. 27, n. 5, p. 590, doi. 10.1111/bpa.12441

By:

Muth, Christiane;
Schröck, Katharina;
Madore, Charlotte;
Hartmann, Kristin;
Fanek, Zain;
Butovsky, Oleg;
Glatzel, Markus;
Krasemann, Susanne

Publication type:

Article

Vaccination with Dendritic Cells Pulsed with Peptides of Myelin Basic Protein Promotes Functional Recovery from Spinal Cord Injury.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 25, p. 8808, doi. 10.1523/JNEUROSCI.23-25-08808.2003

By:

Hauben, Ehud;
Gothilf, Amalia;
Cohen, Avl;
Butovsky, Oleg;
Nevo, Uri;
Smirnov, Igor;
Yoles, Eti;
Akselrod, Solange;
Schwartz, Michal

Publication type:

Article

CX3CR1-CCR2-dependent monocyte-microglial signaling modulates neurovascular leakage and acute injury in a mouse model of childhood stroke.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 10, p. 1919, doi. 10.1177/0271678X18817663

By:

Faustino, Joel;
Chip, Sophorn;
Derugin, Nikita;
Jullienne, Amandine;
Hamer, Mary;
Haddad, Elizabeth;
Butovsky, Oleg;
Obenaus, Andre;
Vexler, Zinaida S

Publication type:

Article

Microglia in the aged brain develop a hypoactive molecular phenotype after surgery.

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03307-0

By:

Yin, Zhuoran;
Leonard, Anna K.;
Porto, Carl M.;
Xie, Zhongcong;
Silveira, Sebastian;
Culley, Deborah J.;
Butovsky, Oleg;
Crosby, Gregory

Publication type:

Article

Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.

Published in:

2020

By:

Roy, Ethan R.;
Wang, Baiping;
Ying-wooi Wan;
Chiu, Gabriel;
Cole, Allysa;
Zhuoran Yin;
Propson, Nicholas E.;
Yin Xu;
Jankowsky, Joanna L.;
Zhandong Liu;
Lee, Virginia M.-Y.;
Trojanowski, John Q.;
Ginsberg, Stephen D.;
Butovsky, Oleg;
Hui Zheng;
Wei Cao;
Wan, Ying-Wooi;
Yin, Zhuoran;
Xu, Yin;
Liu, Zhandong

Publication type:

journal article

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 9, p. 3063, doi. 10.1172/JCI62636

By:

Butovsky, Oleg;
Siddiqui, Shafiuddin;
Gabriely, Galina;
Lanser, Amanda J.;
Dake, Ben;
Murugaiyan, Gopal;
Doykan, Camille E.;
Wu, Pauline M.;
Gali, Reddy R.;
Iyer, Lakshmanan K.;
Lawson, Robert;
Berry, James;
Krichevsky, Anna M.;
Cudkowicz, Merit E.;
Weiner, Howard L.

Publication type:

Article

Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 4, p. 905, doi. 10.1172/JCI26836

By:

Butovsky, Oleg;
Landa, Gennady;
Kunis, Gilad;
Ziv, Yaniv;
Avidan, Hila;
Greenberg, Nadav;
Schwartz, Adi;
Smirnov, Igor;
Pollack, Ayala;
Jung, Steffen;
Schwartz, Michal

Publication type:

Article

Characterisation of Immune and Neuroinflammatory Changes Associated with Chemotherapy-Induced Peripheral Neuropathy.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170814

By:

Makker, Preet G. S.;
Duffy, Samuel S.;
Lees, Justin G.;
Perera, Chamini J.;
Tonkin, Ryan S.;
Butovsky, Oleg;
Park, Susanna B.;
Goldstein, David;
Moalem-Taylor, Gila

Publication type:

Article

Dark microglia: A new phenotype predominantly associated with pathological states.

Published in:

Glia (0894-1491), 2016, v. 64, n. 5, p. 826, doi. 10.1002/glia.22966

By:

Bisht, Kanchan;
Sharma, Kaushik P.;
Lecours, Cynthia;
Gabriela Sánchez, Maria;
El Hajj, Hassan;
Milior, Giampaolo;
Olmos‐Alonso, Adrián;
Gómez‐Nicola, Diego;
Luheshi, Giamal;
Vallières, Luc;
Branchi, Igor;
Maggi, Laura;
Limatola, Cristina;
Butovsky, Oleg;
Tremblay, Marie‐Ève

Publication type:

Article

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

Published in:

Glia (0894-1491), 2015, v. 63, n. 9, p. 1606, doi. 10.1002/glia.22831

By:

Verheijden, Simon;
Beckers, Lien;
Casazza, Andrea;
Butovsky, Oleg;
Mazzone, Massimiliano;
Baes, Myriam

Publication type:

Article

The microbiota restrains neurodegenerative microglia in a model of amyotrophic lateral sclerosis.

Published in:

Microbiome, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40168-022-01232-z

By:

Cox, Laura M.;
Calcagno, Narghes;
Gauthier, Christian;
Madore, Charlotte;
Butovsky, Oleg;
Weiner, Howard L.

Publication type:

Article

Depletion of microglia and inhibition of exosome synthesis halt tau propagation.

Published in:

Nature Neuroscience, 2015, v. 18, n. 11, p. 1584, doi. 10.1038/nn.4132

By:

Asai, Hirohide;
Ikezu, Seiko;
Tsunoda, Satoshi;
Medalla, Maria;
Luebke, Jennifer;
Haydar, Tarik;
Wolozin, Benjamin;
Butovsky, Oleg;
Kügler, Sebastian;
Ikezu, Tsuneya

Publication type:

Article

Corrigendum: Identification of a unique TGF-β-dependent molecular and functional signature in microglia.

Published in:

Nature Neuroscience, 2014, v. 17, n. 9, p. 1286, doi. 10.1038/nn0914-1286d

By:

Butovsky, Oleg;
Jedrychowski, Mark P;
Moore, Craig S;
Cialic, Ron;
Lanser, Amanda J;
Gabriely, Galina;
Koeglsperger, Thomas;
Dake, Ben;
Wu, Pauline M;
Doykan, Camille E;
Fanek, Zain;
Liu, LiPing;
Chen, Zhuoxun;
Rothstein, Jeffrey D;
Ransohoff, Richard M;
Gygi, Steven P;
Antel, Jack P;
Weiner, Howard L

Publication type:

Article

Identification of a unique TGF-β-dependent molecular and functional signature in microglia.

Published in:

Nature Neuroscience, 2014, v. 17, n. 1, p. 131, doi. 10.1038/nn.3599

By:

Butovsky, Oleg;
Jedrychowski, Mark P;
Moore, Craig S;
Cialic, Ron;
Lanser, Amanda J;
Gabriely, Galina;
Koeglsperger, Thomas;
Dake, Ben;
Wu, Pauline M;
Doykan, Camille E;
Fanek, Zain;
Liu, LiPing;
Chen, Zhuoxun;
Rothstein, Jeffrey D;
Ransohoff, Richard M;
Gygi, Steven P;
Antel, Jack P;
Weiner, Howard L

Publication type:

Article

Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39857-9

By:

Abou-El-Hassan, Hadi;
Rezende, Rafael M.;
Izzy, Saef;
Gabriely, Galina;
Yahya, Taha;
Tatematsu, Bruna K.;
Habashy, Karl J.;
Lopes, Juliana R.;
de Oliveira, Gislane L. V.;
Maghzi, Amir-Hadi;
Yin, Zhuoran;
Cox, Laura M.;
Krishnan, Rajesh;
Butovsky, Oleg;
Weiner, Howard L.

Publication type:

Article

The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes.

Published in:

2022

By:

West, Phillip K.;
McCorkindale, Andrew N.;
Guennewig, Boris;
Ashhurst, Thomas M.;
Viengkhou, Barney;
Hayashida, Emina;
Jung, So Ri;
Butovsky, Oleg;
Campbell, Iain L.;
Hofer, Markus J.

Publication type:

journal article

Weekly Vaccination with Copaxone (Glatiramer Acetate) as a Potential Therapy for Dry Age-Related Macular Degeneration.

Published in:

Current Eye Research, 2008, v. 33, n. 11/12, p. 1011, doi. 10.1080/02713680802484637

By:

Landa, Gennady;
Butovsky, Oleg;
Shoshani, Johai;
Schwartz, Michal;
Pollack, Ayala

Publication type:

Article

Sex‐specific transcriptome of spinal microglia in neuropathic pain due to peripheral nerve injury.

Published in:

Glia (0894-1491), 2022, v. 70, n. 4, p. 675, doi. 10.1002/glia.24133

By:

Fiore, Nathan T.;
Yin, Zhuoran;
Guneykaya, Dilansu;
Gauthier, Christian D.;
Hayes, Jessica P.;
D'Hary, Aaron;
Butovsky, Oleg;
Moalem‐Taylor, Gila

Publication type:

Article

Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01439-z

By:

Shi, Haoshen;
Yin, Zhuoran;
Koronyo, Yosef;
Fuchs, Dieu-Trang;
Sheyn, Julia;
Davis, Miyah R.;
Wilson, Jered W.;
Margeta, Milica A.;
Pitts, Kristen M.;
Herron, Shawn;
Ikezu, Seiko;
Ikezu, Tsuneya;
Graham, Stuart L.;
Gupta, Vivek K.;
Black, Keith L.;
Mirzaei, Mehdi;
Butovsky, Oleg;
Koronyo-Hamaoui, Maya

Publication type:

Article

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07295-7

By:

Lund, Harald;
Pieber, Melanie;
Parsa, Roham;
Han, Jinming;
Grommisch, David;
Ewing, Ewoud;
Kular, Lara;
Needhamsen, Maria;
Espinosa, Alexander;
Nilsson, Emma;
Överby, Anna K.;
Butovsky, Oleg;
Jagodic, Maja;
Zhang, Xing-Mei;
Harris, Robert A.

Publication type:

Article

Acute microglia ablation induces neurodegeneration in the somatosensory system.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05929-4

By:

Rubino, Stephen J.;
Mayo, Lior;
Wimmer, Isabella;
Siedler, Victoria;
Brunner, Florian;
Hametner, Simon;
Madi, Asaf;
Lanser, Amanda;
Moreira, Thais;
Donnelly, Dustin;
Cox, Laura;
Rezende, Rafael Machado;
Butovsky, Oleg;
Lassmann, Hans;
Weiner, Howard L.

Publication type:

Article

Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.

Published in:

Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-023-00700-w

By:

Bosch, Megan E.;
Dodiya, Hemraj B.;
Michalkiewicz, Julia;
Lee, Choonghee;
Shaik, Shabana M.;
Weigle, Ian Q.;
Zhang, Can;
Osborn, Jack;
Nambiar, Aishwarya;
Patel, Priyam;
Parhizkar, Samira;
Zhang, Xiaoqiong;
Laury, Marie L.;
Mondal, Prasenjit;
Gomm, Ashley;
Schipma, Matthew John;
Mallah, Dania;
Butovsky, Oleg;
Chang, Eugene B.;
Tanzi, Rudolph E.

Publication type:

Article

Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury.

Published in:

2021

By:

Zrzavy, Tobias;
Schwaiger, Carmen;
Wimmer, Isabella;
Berger, Thomas;
Bauer, Jan;
Butovsky, Oleg;
Schwab, Jan M;
Lassmann, Hans;
Höftberger, Romana

Publication type:

journal article

Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.

Published in:

2017

By:

Zrzavy, Tobias;
Hametner, Simon;
Wimmer, Isabella;
Butovsky, Oleg;
Weiner, Howard L.;
Lassmann, Hans

Publication type:

journal article

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.

Published in:

2015

By:

Butovsky, Oleg;
Jedrychowski, Mark P;
Cialic, Ron;
Krasemann, Susanne;
Murugaiyan, Gopal;
Fanek, Zain;
Greco, David J;
Wu, Pauline M;
Doykan, Camille E;
Kiner, Olga;
Lawson, Robert J;
Frosch, Matthew P;
Pochet, Nathalie;
Fatimy, Rachid El;
Krichevsky, Anna M;
Gygi, Steven P;
Lassmann, Hans;
Berry, James;
Cudkowicz, Merit E;
Weiner, Howard L

Publication type:

journal article

Targeting mi R-155 restores abnormal microglia and attenuates disease in SOD1 mice.

Published in:

Annals of Neurology, 2015, v. 77, n. 1, p. 75, doi. 10.1002/ana.24304

By:

Butovsky, Oleg;
Jedrychowski, Mark P.;
Cialic, Ron;
Krasemann, Susanne;
Murugaiyan, Gopal;
Fanek, Zain;
Greco, David J.;
Wu, Pauline M.;
Doykan, Camille E.;
Kiner, Olga;
Lawson, Robert J.;
Frosch, Matthew P.;
Pochet, Nathalie;
Fatimy, Rachid El;
Krichevsky, Anna M.;
Gygi, Steven P.;
Lassmann, Hans;
Berry, James;
Cudkowicz, Merit E.;
Weiner, Howard L.

Publication type:

Article

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood.

Published in:

Nature Neuroscience, 2006, v. 9, n. 2, p. 268, doi. 10.1038/nn1629

By:

Ziv, Yaniv;
Ron, Noga;
Butovsky, Oleg;
Landa, Gennady;
Sudai, Einav;
Greenberg, Nadav;
Cohen, Hagit;
Kipnis, Jonathan;
Schwartz, Michal

Publication type:

Article

Excess Circulating Alternatively Activated Myeloid (M2) Cells Accelerate ALS Progression While Inhibiting Experimental Autoimmune Encephalomyelitis.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026921

By:

Vaknin, Ilan;
Kunis, Gilad;
Miller, Omer;
Butovsky, Oleg;
Bukshpan, Shay;
Beers, David R.;
Henkel, Jenny S.;
Yoles, Eti;
Appel, Stanley H.;
Schwartz, Michal

Publication type:

Article

ISDN2014_0028: REMOVED: Targeting miR‐155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS.

Published in:

International Journal of Developmental Neuroscience, 2015, v. 47, p. 5, doi. 10.1016/j.ijdevneu.2015.04.022

By:

Butovsky, Oleg;
Jedrychowski, Mark P.;
Cialic, Ron;
Murugaiyan, Gopal;
Wu, Pauline M.;
Doykan, Camille E.;
Fanek, Zain;
Greco, David J.;
Kiner, Olga;
Lawson, Robert J.;
Frosch, Matthew P.;
Pochet, Nathalie;
Krichevsky, Anna M.;
Gygi, Steven P.;
Berry, James;
Cudkowicz, Merit E.;
Weiner, Howard L.

Publication type:

Article

Identification of a unique molecular and functional microglia signature in health and disease.

Published in:

International Journal of Developmental Neuroscience, 2015, v. 47, p. 5, doi. 10.1016/j.ijdevneu.2015.04.022

By:

Butovsky, Oleg;
Jedrychowski, Mark P.;
Moore, Craig S.;
Cialic, Ron;
Lanser, Amanda J.;
Gabriely, Galina;
Koeglsperger, Thomas;
Dake, Ben;
Wu, Pauline M.;
Doykan, Camille E.;
Fanek, Zain;
Liu, LiPing;
Chen, Zhuoxun;
Rothstein, Jeffrey D.;
Ransohoff, Richard M.;
Gygi, Steven P.;
Antel, Jack P.;
Weiner, Howard L.

Publication type:

Article

Correction to: Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy.

Published in:

2020

By:

Kempthorne, Liam;
Yoon, Hyejin;
Madore, Charlotte;
Smith, Scott;
Wszolek, Zbigniew K.;
Rademakers, Rosa;
Kim, Jungsu;
Butovsky, Oleg;
Dickson, Dennis W.

Publication type:

Correction Notice

Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00947-0

By:

Kempthorne, Liam;
Yoon, Hyejin;
Madore, Charlotte;
Smith, Scott;
Wszolek, Zbigniew K.;
Rademakers, Rosa;
Kim, Jungsu;
Butovsky, Oleg;
Dickson, Dennis W.

Publication type:

Article

Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0735-1

By:

Hartmann, Kristin;
Sepulveda-Falla, Diego;
Rose, Indigo V. L.;
Madore, Charlotte;
Muth, Christiane;
Matschke, Jakob;
Butovsky, Oleg;
Liddelow, Shane;
Glatzel, Markus;
Krasemann, Susanne

Publication type:

Article

Does Inflammation in an Autoimmune Disease Differ from Inflammation in Neurodegenerative Diseases? Possible Implications for Therapy.

Published in:

Journal of NeuroImmune Pharmacology, 2006, v. 1, n. 4, p. 4, doi. 10.1007/s11481-005-9010-2

By:

Schwartz, Michal;
Butovsky, Oleg;
Kipnis, Jonathan

Publication type:

Article

Differential contribution of microglia and monocytes in neurodegenerative diseases.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 5, p. 809, doi. 10.1007/s00702-017-1795-7

By:

Baufeld, Caroline;
O’Loughlin, Elaine;
Calcagno, Narghes;
Madore, Charlotte;
Butovsky, Oleg

Publication type:

Article

Xenon gas (Xe) treatment to restore microglial functions in Alzheimer's disease (AD).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076467

By:

Brandao, Wesley N;
Yin, Zhuoran;
Kleemann, Kilian;
Zhang, Xiaoming;
Rosenzweig, Neta;
Jain, Nimansha;
Jones, Mathew Blurton;
Holtzman, David M.;
Ilin, Ilya;
Weiner, Howard L;
Butovsky, Oleg

Publication type:

Article

APOE4 impairs microglia‐astrocyte response in Alzheimer's disease by inducing TGFβ‐mediated checkpoints.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076510

By:

Butovsky, Oleg;
Yin, Zhuoran;
Rosenzweig, Neta;
Kleemann, Kilian;
Zhang, Xiaoming;
Brandao, Wesley N;
Margeta, Milica;
Schroeder, Caitlin M;
Silveira, Sebastian;
Gauthier, Christian;
Mallah, Dania;
Pitts, Kristen;
Durao, Ana;
Herron, Shawn;
Shorey, Hannah;
Cheng, Yiran;
Barry, Jen‐Li;
Wakelin, Sam;
Rhee, Jared;
Yung, Anthony

Publication type:

Article

APOE‐4 dependent dysfunctional neutrophil‐microglia crosstalk accelerates Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075072

By:

Rosenzweig, Neta;
Kleemann, Kilian;
Grucci, Madeline;
Aronchik, Micheal;
Butovsky, Oleg

Publication type:

Article

APOE4 impairs microglia‐astrocyte response in Alzheimer's disease by inducing TGFβ‐mediated checkpoints.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076510

By:

Butovsky, Oleg;
Yin, Zhuoran;
Rosenzweig, Neta;
Kleemann, Kilian;
Zhang, Xiaoming;
Brandao, Wesley N;
Margeta, Milica;
Schroeder, Caitlin M;
Silveira, Sebastian;
Gauthier, Christian;
Mallah, Dania;
Pitts, Kristen;
Durao, Ana;
Herron, Shawn;
Shorey, Hannah;
Cheng, Yiran;
Barry, Jen‐Li;
Wakelin, Sam;
Rhee, Jared;
Yung, Anthony

Publication type:

Article

APOE‐4 dependent dysfunctional neutrophil‐microglia crosstalk accelerates Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075072

By:

Rosenzweig, Neta;
Kleemann, Kilian;
Grucci, Madeline;
Aronchik, Micheal;
Butovsky, Oleg

Publication type:

Article

Treatment of Alzheimer's disease by modulation of microglial neuroinflammation by nasal anti‐CD3 mAb.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068761

By:

Weiner, Howard L;
Lopes, Juliana;
Zhang, Xiaoming;
Baufeld, Caroline;
Rezende, Rafael;
Selkoe, Dennis J;
Butovsky, Oleg

Publication type:

Article

APOE4 Impairs Microglia Response to Neurodegeneration in Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.063641

By:

Rosenzweig, Neta;
Yin, Zhuoran;
Madore, Charlotte;
Butovsky, Oleg

Publication type:

Article

P1‐216: SEX‐SPECIFIC PERTURBATIONS IN CEREBRAL AMYLOIDOSIS AND MICROGLIA PHENOTYPES IN ANTIBIOTIC‐TREATED APPSWE/PS1L166P TRANSGENIC MICE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P319, doi. 10.1016/j.jalz.2019.06.771

By:

Dodiya, Hemraj B.;
Kuntz, Thomas;
Shaik, Shabana M.;
Baufeld, Caroline;
Leibowitz, Jeffrey;
Zhang, Xulun;
Gottel, Neil;
Zhang, Xiaoqiong;
Butovsky, Oleg;
Gilbert, Jack A.;
Sisodia, Sangram S.

Publication type:

Article

MICROGLIAL EXOSOMES PROPAGATE TAU PROTEIN FROM THE ENTORHINAL CORTEX TO THE HIPPOCAMPUS: AN EARLY PATHOPHYSIOLOGY OF ALZHEIMER’S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P339, doi. 10.1016/j.jalz.2016.06.624

By:

Ikezu, Tsuneya;
Ikezu, Seiko;
Varnum, Megan;
Wolozin, Benjamin;
Butovsky, Oleg;
Kügler, Sebastian;
Medalla, Maria;
Luebke, Jennfier;
Haydar, Tarik F.

Publication type:

Article

P-009: T cell-based vaccination of AD-transgenic mice induces plaque clearance, hippocampal neurogenesis and improves learning and memory abilities: A key role of microglial activation that express IGF-I

Published in:

2007

By:

Koronyo, Maya;
Butovsky, Oleg;
Kunis, Gilad;
Ophir, Eran;
Landa, Gennady;
Cohen, Hagit;
Schwartz, Michal

Publication type:

Abstract